Articles tagged with Methadone
Researchers have discovered that methadone has surprising killing power against leukemia cells, including those resistant to chemotherapy and radiation. The agent activates the mitochondrial pathway, inducing apoptosis in cancer cells without harming non-leukemic blood cells.
Researchers found that 77% of methadone users with low levels had no significant cardiac abnormalities, while 60% of non-methadone users had identifiable evidence of cardiac disease. The study suggests a link between methadone and sudden cardiac death, potentially necessitating additional safeguards before therapy.
A study at McGill University Health Centre shows that combining methadone with innovative case management can provide relief for patients with chronic pain. The program, which includes regular phone calls and a pain diary, resulted in 57% of patients being satisfied or very satisfied after nine months.
A new study from British Columbia found that Aboriginal people with heroin addiction are less likely to use methadone maintenance therapy. Compared to non-Aboriginal counterparts, Aboriginal participants were significantly lower rates of methadone use throughout the follow-up period.
A new study has identified dihydrocodeine as an equally effective alternative to expensive methadone treatment for heroin addiction. The prescription painkiller is cheaper, safer and less toxic, with estimated annual costs of £713 compared to £1,500 for methadone.
Researchers from NDRI found that offering innovative vocational programs with active outreach and support resulted in higher participation among unemployed methadone patients. Most 'needy' patients became more engaged when offered vocational counseling, leading to reduced relapse rates.
A study analyzing data from over 7,250 patients in Zurich found a significant decrease in new heroin users between 1990 and 2002. The incidence of heroin use dropped from 850 to 150, while the overall number of heroin dependents only declined by 4% per year.
A new study found that effective methadone doses vary widely among patients, with some achieving abstinence on as little as 1.5 mg and others requiring up to 191.2 mg. Patients with posttraumatic stress disorder, depression, or a history of previous detoxifications from heroin tend to require higher doses.
A study by Yale University researchers found office-based buprenorphine treatment reaches individuals who are unable to use methadone, with key demographic differences including age, sex, and employment status. The treatment has shown success in reaching patients with lower rates of injection drug use and hepatitis C infection.
A study found that only 12% of jails continued methadone treatments for withdrawal, while 48% failed to provide appropriate detoxification methods. The lack of coordination between jails and community clinics is a major concern.
A new treatment option for heroin addiction has shown a promising 75% success rate in reducing opiate use, according to a recent study. The combination of buprenorphine and intensive psychosocial therapy was found to be effective in preventing relapse and reducing criminal activity among patients.
A study by Dr. Steven L. Batki found that methadone treatment significantly improved the completion of TB therapy in opioid-dependent patients with latent TB infection. Patients receiving standard or minimal methadone treatment had higher completion rates compared to those receiving routine care.
A study examines the potential of pharmacogenomic testing to help drug-treatment centers select suitable treatment regimens for opiate-addicted patients. The research investigates genetic polymorphisms affecting opioid metabolism, aiming to improve pain management and drug-abuse treatment.
A six-month study found that 82% of stable methadone patients remained clinically stable under primary care physician treatment. Patients reported higher satisfaction rates and physicians felt confident in providing this type of care.
A recent study found that treatments like levomethadyl acetate (LAAM) and buprenorphine were more effective in treating heroin addiction than low-dose methadone. The study showed significant reductions in heroin use for patients on LAAM, buprenorphine, or high-dose methadone.
Expansion of methadone programs would reduce the spread of HIV to the general population, resulting in significant health benefits. The study estimated that expansion of methadone treatment capacity would cost between $8,200 and $10,900 for every quality-adjusted life year gained.
A new study published in the Journal of the American Medical Association found that longer-term methadone maintenance therapy significantly surpasses short-term detoxification and psychosocial counseling. The study revealed higher treatment retention rates and lower heroin use rates among participants in the MMT group compared to those...
A UCSF study compared methadone maintenance with a 180-day detoxification program and found that methadone maintenance resulted in lower heroin use rates and fewer drug-related HIV risk behaviors. The study suggests that pharmacological tools are needed to combat heroin addiction.
A NIDA-supported survey found that two-thirds of NYC clinicians are willing to provide methadone maintenance treatment in their offices. This could expand access to treatment for the 600,000 diagnosed heroin addicts in the US who currently receive fewer than 20% of treatment.
Researchers found that high-dose methadone (80-100mg) resulted in a sharper reduction in illicit opioid use compared to moderate doses (40-50mg), with some patients requiring even higher doses for optimal benefit. The study, conducted at Johns Hopkins Medicine, underscores the need for more consistent treatment dosages nationwide.
A new Johns Hopkins study suggests better ways of taking LAAM, a drug similar to methadone, by increasing dosage frequency and reducing side effects. The study found significant reductions in heroin use among participants, with over 80% staying with the treatment, and increased patient adherence due to its longer-acting benefits.