Articles tagged with Transplantation
Research on container-grown trees found that deep structural roots contribute to physiological stresses and abnormally deep roots. Remediation techniques reduced growth delays in pin oak, while littleleaf linden showed more persistent issues after three years.
Children of minority races are less likely to get kidney transplants before they need dialysis, and blacks with no health insurance face a higher risk of death while waiting for a transplant. Certain racial groups have lower rates of preemptive transplantation and are more likely to die than others
Fecal microbiota transplants have shown high efficacy in treating recurrent C. difficile infections, with a success rate of 91% in one study. The procedure has also been effective in treating Inflammatory Bowel Disease, particularly when done recurrently. Researchers found that fecal transplant is a safe and effective treatment option ...
A new study published in the American Journal of Transplantation reveals that women who undergo a kidney transplant can successfully carry a pregnancy with a live birth rate of 73.5%. However, pregnancy complications such as preeclampsia and preterm delivery are common, especially among those pregnant within two years of the transplant.
African-American donors were more likely to be related to the transplant recipient and to donate to their parents compared to Caucasian donors. The study also found that most African-American kidney donors are men and younger than white donors, which may explain why African-American children are more often able to donate to their parents.
A recent study found that public reporting of transplant centers' success rates has not improved care for patients, with wide gaps remaining between the best and worst clinics. The new method revealed that gaps persisted after public reporting was introduced in 2001, missing potential improvements in patient outcomes.
A new study from the University of Pittsburgh School of Medicine found that anti-reflux surgery can preserve lung function in patients with end-stage pulmonary disease both before and after transplantation. The procedure was associated with improved lung function, reduced episodes of acute rejection and pneumonia, and may help extend t...
A study published in JAMA found that younger black patients undergoing dialysis have significantly higher mortality rates compared to their white counterparts. The disparity is attributed to differential access to transplantation and inadequate dialysis care. Researchers emphasize the need for targeted interventions to address these di...
A new Johns Hopkins research published in JAMA finds that younger black patients on kidney dialysis face a higher risk of death compared to equally sick white counterparts. The study highlights a long-standing racial disparity in outcomes for African-American patients with end-stage kidney disease.
Researchers found that pediatric liver-transplant patients required a second vaccination to defend against the pandemic virus, as a single-dose H1N1 vaccine did not provide adequate protection. A study published in Liver Transplantation revealed that increasing time since transplant correlated with successful immune response.
A study found that children with dilated cardiomyopathy who have congestive heart failure, severe disease, increased age, and dilation of the left ventricle are at higher risk of death or transplantation. The study's findings may lead to broadened indications for heart transplantation in more children.
Patients with idiopathic pulmonary fibrosis (IPF) face a higher risk of death when accessing tertiary care centers, according to recent research. Early detection and referral methods can shorten the time from symptoms onset to referral, ultimately improving patient outcomes.
Researchers developed a new twin-head 'V' high-wire cucumber system to improve productivity in greenhouses without increasing crop start-up costs. The study showed that the twin-head system achieved similar plant growth and fruit yield as the conventional single-head system, but with lower production expenses.
Physicians at Washington University used an artificial lung to treat a two-year-old boy with severe pulmonary hypertension, saving his life. The boy, Owen Stark, was initially treated with medication and a ventilator before being placed on the life-support machine called ECMO.
A new study reveals that patients implanted with the HeartMate II left ventricular assist device (LVAD) are at a higher risk of internal bleeding than those who received an earlier model. The research found nearly 22% of patients experienced gastrointestinal bleeding, while eight percent suffered from major adverse neurological events.
A Canadian study found Aboriginal children with kidney failure were less likely to receive a kidney transplant compared to white children. The study revealed that Aboriginal children had more immune-mediated kidney diseases and shorter waiting times on dialysis before transplantation, leading to lower rates of successful transplants.
Cardiac specialists will use new guidelines to determine who should receive a mechanical heart-pumping device. The guidelines have the potential to change clinical practice patterns for patients with severe heart failure. Dr. Morgan's presentation at the ISHLT annual meeting in San Diego highlights the importance of these changes.
A study at Henry Ford Hospital found that non-cardiac surgery can be performed safely in patients with a heart device. The study looked at the management of blood-thinning medication and found no complications due to bleeding or device malfunctions.
Spanish researchers found that liver transplant recipients who quit smoking have a lower incidence of smoking-related malignancies, while active smoking increases the risk. Smoking cessation after liver transplantation reduces the incidence of malignancy, suggesting it may be a protective factor.
Research reveals significant increases in ESRD incidence among patients with lupus nephritis, particularly in younger populations and African Americans. Despite advances in treatment, outcomes have not improved over a decade, highlighting the need for further research to identify modifiable risk factors and interventions.
The current US kidney allocation system prioritizes wait time over post-transplant survival, leading to higher repeat transplantation rates. Researchers propose ranking kidneys by potential post-transplant survival and matching them with candidates who have the longest expected survival.
A study published in the Clinical Journal of the American Society Nephrology found that kidney transplant recipients who engage in little physical activity face increased risks of dying prematurely. The research suggests that patients need to exercise to fend off an early death and maintain heart health, which is crucial for these indi...
Researchers found a significant association between IL28B genotypes and interferon-based antiviral treatment outcomes, as well as graft inflammation caused by hepatitis C virus (HCV). The presence of G-allele serves as a marker for severe HCV-induced graft inflammation and predictor of unsuccessful treatment.
Researchers tracked corneal transplant success in young patients and found substantial improvement in vision for most children with keratoconus. The study revealed that infants had lower success rates due to related illnesses, while older children fared better.
The AAAS has awarded four researchers with the Joshua E. Neimark Memorial Travel Assistance Award to study stem cell transplantation, sustainable growth, women in academia, and conservation science. The winners will attend the 2011 Annual Meeting of the American Association for the Advancement of Science.
A study published in Hepatology found that HIV-infected patients with liver cancer have a higher risk of dropping off the transplantation wait list compared to HIV-negative patients. Despite this, overall survival and recurrence-free survival rates are not significantly affected following liver transplantation.
A new study found that patients who return to dialysis after a kidney transplant failure can survive just as well on home dialysis as hospital dialysis. However, only 18% of these patients choose the home version due to concerns and limited education about its benefits.
A study published in Liver Transplantation found that over half of liver transplant patients develop metabolic syndrome, a condition associated with obesity, hypertension, and diabetes. This increases their risk for cardiovascular disease and mortality, but not necessarily mortality itself.
Researchers have found that paper mulches can be an effective alternative to traditional polyethylene mulches in commercial vegetable production. Four types of paper mulches were compared with black plastic mulch and found to control weeds as well as or better than polyethylene in some situations.
A randomized controlled trial found that a lung protective strategy increased the number of lungs eligible for donation by nearly doubling it compared to conventional ventilation. This method included lower tidal volumes and higher positive end-expiratory pressure levels.
Research shows that moderate drinking can help prevent diabetes and premature death in kidney transplant recipients, but excessive weight may be detrimental. On the other hand, low dialysis calcium levels have been linked to an increased risk of sudden cardiac arrest among patients on dialysis.
A centralized reference pool could help employers and workers by providing a legal safe harbor for employees and allowing them access to references while also enabling recourse through a neutral third party. This system would promote the flow of accurate information with low transaction costs, making labor markets more efficient.
A study found that a common transmissible strain of Pseudomonas aeruginosa is prevalent among cystic fibrosis patients in Canada, particularly in those infected with strain A, which is associated with a higher risk of death or lung transplantation. The study suggests cross-infection between CF centers in the UK and Canada.
A new study published in Liver Transplantation found that obese children have a higher mortality risk after primary liver transplantation, while severely thin pediatric patients face an early mortality risk within the first year. The study suggests post-metabolic syndrome may contribute to late morbidity and mortality.
A recent study led by St. Michael's nephrologist Dr. Ramesh Prasad has found that South Asian patients are more than twice as likely to suffer a heart attack after a kidney transplant compared to Caucasian, black and East Asian men and women.
Italian researchers found that liver transplant candidates with a strong religious connection had better post-transplant survival rates. The study also revealed that religiosity can prolong life span in individuals undergoing liver transplantation.
A recent study found that South Asian kidney transplant recipients experience a significantly higher risk of heart problems post-transplant. The research identified ethnicity as a key risk factor for cardiovascular events in this population, highlighting the need for tailored care and registry categories.
Researchers have identified a gene likely responsible for Fuchs corneal dystrophy, an inheritable genetic disorder causing corneal transplant operations. The TCF4 gene variation significantly increases the risk of developing the disease.
Researchers successfully reshaped the gut microbiome of rats, inducing long-term changes that could lead to new treatments for intestinal diseases. The study found that transplantation alone was sufficient to introduce new species into the intestinal microbial composition.
A Henry Ford Hospital study found that the Donor Risk Index does not significantly impact liver transplant outcomes on a small scale. Hepatitis C was shown to remain a major contributor to poor graft survival in transplant patients. The study confirms this finding despite large-scale data suggesting otherwise, highlighting the importan...
A new trend in managing benign biliary strictures is emerging with the use of a removable covered SEMS. The stent, made of nitinol wire, imparts an outward radial force on the biliary duct to establish patency and has a radio-opaque string for easy retrieval.
Researchers suggest treatments used on liver cancers beyond Milan criteria be applied to all patients with HCC listed for transplantation. Ablation and waiting can control tumors, allowing time to determine tumor biology and reducing recurrence rates.
A study found significant variability in 5-year patient survival rates for lung transplantation centers in the US, with risks of death ranging from 30% lower to 70% higher. Despite controlling for procedural volume, center performance remained significant, suggesting true differences in quality of care.
Liver transplant patients receiving cyclosporine for immunosuppression are at higher risk of developing de novo cancer, particularly those transplanted in recent years and younger than 50. The study found a significant association between C2 monitoring and increased early de novo cancer risk.
A new study published in Restoration Ecology reveals that coral transplantation is an effective and affordable solution for reef restoration. The research team transplanted elkhorn coral fragments onto a damaged reef in the British Virgin Islands, achieving significant growth and survival rates over four years.
Researchers at UCLA Medical Center found antiviral therapy during compensated cirrhosis to be the most cost-effective approach for treating HCV patients with advanced liver disease. Treatment initiated before progression to more advanced liver disease resulted in improved survival and decreased costs compared to other strategies.
A recent study found that extending hepatitis C treatment for liver transplant patients beyond current standards results in high clearance rates of the virus from the blood. The study also showed a low relapse rate, with only two patients out of 66 eligible for treatment experiencing relapse.
A study investigated transplanting practices during container production of lacebark elm, finding that planting at grade during initial production phase resulted in greater growth. Trees planted below or above grade showed reduced growth in subsequent phases, with those planted at or below grade performing better in the landscape.
Results from two French studies presented at the International Liver CongressTM 2010 show that early liver transplantation can be proposed to non-respondents to steroids, while treatment with combined corticoids plus N-acetyl cysteine (C+NAC) increases survival rates in patients with acute alcoholic hepatitis. The studies add to growin...
A new clinical prediction index can calculate survival for patients with end-stage kidney disease, helping clinicians and patients decide between transplantation or dialysis. The index has been proven to accurately predict mortality among eligible patients.
A study found that sirolimus-based immunosuppression significantly increases survival rates for post-transplant liver cancer patients, while radiofrequency ablation shows promise for very early-stage HCC treatment.
A new study by Henry Ford Hospital finds regadenoson to be a safe alternative to conventional medication used in cardiac nuclear stress tests for heart transplant patients. The drug did not cause adverse side effects such as low blood pressure or heart block, and showed no signs of these conditions.
Scientists have created a bandage that slowly releases nitric oxide, increasing blood flow in laboratory rats. The technology has potential applications for treating diabetic patients and preserving donated organs, suggesting improved outcomes in both conditions.
Researchers at Henry Ford Hospital conducted a study showing that skin transplant surgery is safe and effective in treating vitiligo. The treated area regained an average of 52% of its natural skin color, with some patients experiencing up to 74% regrowth.
Scientists have developed a new bandage that slowly releases nitric oxide, increasing blood flow and regulating body functions. The material is made from zeolites embedded in a water-repellent polymer and has potential applications in therapeutic socks for diabetic patients and organ preservation.
A recent study found that repeated liver stiffness measurements can accurately detect severity of fibrosis in patients with hepatitis C recurrence after a liver transplant. Slow 'fibrosers' progressed at the same rate as non-HCV LT patients, while rapid 'fibrosers' showed significant fibrosis and portal hypertension early on.
Patients with a rare, deadly disease experienced significant reduction in breathlessness using treprostinil, shifting from Class III to Class II NYHA functional class. The treatment improved walking distance and reduced Borg scores, offering substantial improvement in daily capabilities.
A study of 160 kidney transplant patients found that social support was lower in the later transplant period, while medication side effects had a significant impact on quality of life. Researchers highlight the need for more social support and interventions to alleviate medication side effects.
A new study published in the American Journal of Roentgenology found that combining triple-drug TACE with a liver transplant significantly increased long-term survival rates for patients with unresectable liver cancer. The median survival time for patients who underwent the procedure was over 112 months.
A new study reveals that sleep apnea is associated with an increased risk of high blood pressure, heart disease, and stroke in kidney transplant patients. The condition was found to be present in one in four individuals and more than doubled the risk of cardiovascular complications.