Articles tagged with Vaccination
A University of Alberta researcher has developed a method to treat surgical masks, making them effective against airborne viruses. By using a salt-based treatment, the mask's fibre filter can trap and kill viruses, reducing the risk of transmission.
Researchers at UTMB have developed an oral vaccine against salmonella that can be taken by mouth to protect against poisoning. The vaccine was shown to produce strong immunity in mice and holds promise for future use in humans.
Scientists develop a nanoparticle-based method for delivering therapeutic molecules into cells, enabling the induction of strong immune responses against various viruses and diseases. The technique, which harnesses electrically activated gold nanoparticles, demonstrates safety and efficacy in animal studies.
Researchers at The University of Texas Medical Branch at Galveston have developed a novel chikungunya vaccine using an insect-specific virus that doesn't affect humans. The new vaccine elicits strong immune defenses and protects mice and nonhuman primates from disease when exposed to the chikungunya virus.
A Washington State University study found that vaccinating cattle for East Coast fever increases household wealth and income, leading to more food and education. Fewer cattle deaths also enable families to send their daughters to secondary school.
A Drexel study analyzed nearly 200,000 English-language tweets about the HPV vaccine between 2014 and 2015. The results show that 39% of tweets were positive, while negative sentiments accounted for only 25%. Prevention and protection were popular topics in positive tweets, while side effects dominated negative ones.
Researchers found that liposomal lidocaine combined with parental video instruction and oral sucrose significantly reduces acute pain during vaccinations. The study involved 352 healthy infants who received scheduled vaccinations, with the best results seen for those using lidocaine cream consistently.
Researchers developed a standardized approach to analyze full costs of cholera vaccines in developing countries, revealing significant variability in costs. The analysis showed vaccine delivery costs ranging from $0.36 to $6.32 per person vaccinated, with procurement costs varying between $0.29 and $29.70.
Genetic analysis of ancient DNA reveals that the evolution of smallpox occurred far more recently than previously believed, with all available strains having an ancestor no older than 1580. Researchers found two circulating strains of the virus, variola major and minor, after English physician Edward Jenner developed a vaccine in 1796.
A modified rabies virus expressing a protein from the MERS virus protects mice against both diseases. The dual compound could lead to an effective human vaccine for Middle East Respiratory Syndrome and prevent its spread in camels.
Researchers have created two compounds that work as potential vaccines against opioid overdoses, preventing the drugs from entering the central nervous system and inducing addiction. The vaccine candidates showed promising results in mouse tests, with vaccinated mice surviving overdose fatalities at higher rates than unvaccinated mice.
A study published in Cell Reports reveals that the BCG vaccine's broad-spectrum effects could be mediated by metabolic and epigenetic changes in monocytes, leading to trained immunity. This discovery could pave the way for new therapeutic approaches to boost vaccine effectiveness.
Colorado State University's Jean Peccoud leads a multi-institutional team analyzing the nation's biomanufacturing infrastructure security. The project aims to provide specific recommendations to strengthen biomanufacturing processes and ensure data integrity.
Researchers have developed a simple and inexpensive method for stabilizing vaccines at room temperature using nanoparticles, polymers, or sugar. This approach could improve vaccine storage and distribution, especially in remote areas with limited refrigeration, reducing the cost of vaccination programs by nearly 80%.
The first licensed vaccine for the potentially life-threatening dengue virus is predicted to be most cost-effective and effective in reducing the burden of dengue disease in moderate-to-high impacted regions. Routine vaccination could reduce hospital rates by up to 25% in these areas.
A University of Arizona researcher is investigating how men perceive their role in preventing the spread of human papillomavirus (HPV). Her study found that most college-age males had heard of HPV but lacked knowledge about a vaccine that could prevent related cancers for both males and females. The researcher emphasizes the importance...
A team of CNIC scientists has characterized a cell signal called ISGylation that impairs the secretion of exosomes, which are crucial for intercellular communication. The discovery sheds light on how this signal affects exosome formation and could lead to new biomedical applications.
Vaccine producers are accused of using monopoly power to determine who lives or dies, with prices often exceeding $120 per dose in wealthy countries. Experts argue for fair pricing that takes into account research and manufacturing costs, public health importance, and collective value creation.
Researchers at TSRI developed a vaccine that blocks the pain-numbing effects of oxycodone and hydrocodone in animal models, also decreasing the risk of fatal opioid overdose. The vaccine uses the immune system's ability to recognize and neutralize invaders, potentially depriving users of euphoria.
Measles can spread quickly in schools, with one infected child potentially infecting up to 27 others on average. High vaccination rates are necessary to prevent transmission, and historical data from a 1904 outbreak supports this finding.
A recent UBC study found significant variations in kindergarten vaccination rates across Metro Vancouver, with some areas having rates as low as 60%. The study used Vancouver Coastal Health data and analyzed the impact of location, school type, and other factors on vaccine coverage.
Portland State University has been awarded a $100,000 grant by the Bill & Melinda Gates Foundation to develop a new method for stabilizing stool samples. This technology could improve diagnosis and treatment of intestinal parasites in developing countries.
A DNA-based Zika vaccine generated robust antigen-specific antibody and T cell immune responses that protected against infection, brain damage, and death. The vaccine was also neuroprotective, preventing the disease from spreading to the brain in animal models.
Researchers at Georgia Tech developed a unified approach to study behavior's impact on the environment, proposing an 'oscillating tragedy of the commons' that considers co-evolution of actions and environment. Cooperation can prevent tragedies, especially when incentives are aligned with environmental conditions.
The first of five clinical trials for an investigational Zika vaccine began at the Walter Reed Army Institute of Research, testing the safety and ability of the ZPIV vaccine to generate an immune system response. The Phase 1 trial aims to enroll 75 people aged 18-49 with no prior flavivirus infection.
A new U-M vaccine using siderophore molecules prevents E. coli growth in mouse bladders and kidneys, offering hope for a treatment against UTIs. The approach has shown success in mice but is still years away from human trials.
A new study found that patients with rare primary immunodeficiency disorders may be susceptible to serious side effects from the rubella vaccine. The study analyzed data from 14 patients and found that 7 had evidence of persistent rubella virus in their granulomas, leading to skin damage and ulcers.
A vaccine against cutaneous leishmaniasis has been developed using sand fly saliva, which induced antibodies in mice and reduced parasite levels. The study also found lower antibody levels in humans with active cutaneous leishmaniasis.
A team of scientists analyzed TB bacterial strains and found they can be genetically subdivided into generalists with worldwide distribution and specialists with localized ecological niches. Generalists have a slightly increased diversity of antigens, allowing them to adapt more specifically to different human populations.
A study of over 300,000 births found no significant link between Tdap vaccination during pregnancy and microcephaly or structural birth defects. The researchers concluded that the findings support routine Tdap administration during pregnancy.
New research from York University and Xi'an Jiaotong University finds that vaccinating against dengue fever can increase the spread of Zika. The study used mathematical modeling to investigate the effect of dengue vaccination on Zika outbreaks.
Researchers identified 17 cases of subacute sclerosing panencephalitis (SSPE) in California between 1998 and 2016, most developed symptoms after getting measles as infants before being vaccinated. Vaccinating everyone against measles can prevent SSPE, which is fatal and has no cure.
Researchers at the University of Alabama at Birmingham have found that neonatal vaccination with certain bacteria can prevent adult asthma in mice. The protective effect is due to the selection of specific immune system B cells that produce IgA antibodies, which bind and inhibit allergens before triggering asthma.
A WSU-led research team found that a commonly used rabies vaccine produces the same protective antibodies in dogs after being stored for six months at warmer temperatures. This could lead to improved vaccination coverage in hard-to-reach areas of Africa and Asia, reducing the likelihood of rabies returning to communities.
A Rochester Institute of Technology researcher is developing a comprehensive model for affordable vaccines in low-income countries through a three-year grant. The model aims to simulate a coordinated vaccine market that balances affordability with sustainability and profit.
A recent study by Emory Vaccine Center-India collaboration reveals insights into CD8 T cells' role in fighting dengue virus infection. The research shows that these immune cells expand massively but keep cytokine production under control, retaining the ability to kill virus-infected cells.
A new study by Michigan State University researchers demonstrates that digital scans of a young child's fingerprint can be correctly recognized one year later, allowing for proper medical care. The technique has the potential to save millions of lives by tracking vaccination records and providing lifelong identity.
Three different candidate Zika vaccines have been found to protect rhesus monkeys against the disease in trials. The vaccines, tested in preclinical trials, were found to be effective at warding off infection by the Zika virus strain circulating in Brazil and Puerto Rico.
A study finds that Payment by Results (PbR) can lead to ineffective aid distribution due to a lack of accurate data. PbR may reward performance for improvements that would have happened anyway, highlighting the need for robust data sources.
Researchers from UTMB have developed three new potential vaccines against the plague that protect animals from developing pneumonic plague as late as four to five months after vaccination. The vaccines were engineered by deleting and modifying genes in Yersinia pestis bacteria, resulting in safe vaccine candidates.
Researchers at Michigan Technological University provide a detailed overview of Zika's history, transmission modes, and risks, including sexual transmission and miscarriage risks. The study also highlights the connection between dengue virus infection and Zika virus exacerbation.
A modeling study suggests that supplementary vaccination campaigns triggered by measles outbreaks could prevent 28,613 cases over 15 years in high-incidence settings. Vaccination campaigns prompted by serological surveys could prevent more cases, but would need to occur annually in high-incidence settings.
A new study by Thomas Jefferson University shows that community outreach workers may help increase hepatitis B vaccine uptake among Asian Americans, reducing the risk of liver cancer. The program involved lay health workers who provided personalized calls to encourage vaccinations.
A UC Riverside-led study reveals that mother's milk contributes to the development of a baby's own immune system by transferring maternal immune cells. This process, known as 'maternal educational immunity,' enables the baby to gain immunity against infectious agents through exposure to its mother's environment.
IDRI aims to develop a safe and effective Zika vaccine using RNA-based technology, which can be rapidly manufactured without requiring egg growth or bacteria cultivation. The institute plans to leverage the Zika virus's own machinery for expression of immunogenic proteins.
A new Global Burden of Diseases study reveals that while improvements in sanitation and nutrition have led to longer lifespans, significant health challenges like obesity, high blood sugar, and alcohol abuse threaten progress. The study shows that many countries face health challenges despite income growth and education increases.
Researchers created a patented vaccine to combat Fusobacterium necrophorum infection, which affects sheep and cattle with liver abscesses and calf diphtheria.
Researchers develop a portable biological factory platform that can produce pharmaceuticals, specialized therapies, and experimental biomolecules using freeze-dried molecular components. The technology is applied in various fields, including vaccine production and designer antibody development.
Researchers at the University of Pittsburgh School of Medicine have developed two successful Zika vaccines that protect against neurological damage in newborn mice. The microneedle array vaccine showed significant protection, while the adenovirus-based vaccine was used as a proof-of-principle vaccine to test the envelope protein antigen.
The European region is the most skeptical about vaccine safety, with seven countries ranking low in confidence. A global survey of nearly 66,000 people across 67 countries found that public trust in vaccines is precarious and influenced by concerns over side effects and scientific debates.
Researchers in Northwestern China report ongoing transmission of rabies, highlighting challenges in reservoir animals such as dogs and wild foxes. The study emphasizes the need for oral vaccines for these animals, citing limited evidence on vaccination dosing and scheduling.
A new analysis of the world's first marketed dengue virus vaccine (Dengvaxia) provides critical insights for policymakers in dengue-affected countries. The study found that seropositive recipients gained a substantial benefit from vaccination, being 90% less likely to be hospitalized after contracting dengue.
Researchers find that a widely available dengue vaccine could worsen the disease in some settings, particularly in low-transmission areas. The vaccine has shown to reduce illness and hospitalization by 20-30% in high-transmission countries but may increase these rates in locations with lower transmission.
A new study suggests that the dengue vaccine can prime the immune system to make future infections more severe, particularly in people who have never been exposed before. The research recommends testing individuals before vaccination to minimize risks and maximize benefits.
Researchers tested an oral rabies vaccine in wild populations of Ethiopian wolves, with promising results. The trials found that 86% of vaccinated wolves had sufficient levels of protective antibodies, and all but one were alive 14 months later.
A Brazilian study found that some cases of Zika virus may be misreported as dengue, leading to an underestimate of the epidemic's size. The researchers analyzed blood samples from 800 people treated for suspected dengue and found over 100 positive for Zika.
New research investigates how personality characteristics influence friendship patterns and attitudes towards vaccines. Studies also reveal the impact of spontaneous trait inferences on social media.
A 20-year study shows that probiotic supplementation in newborns can provide long-term protection against allergies. Meanwhile, a new vaccine for cat allergies lasts 8 times longer than existing ones, while research on dairy farm kids' immunity to milk allergies may lead to an asthma vaccine.
A study found that parents are more likely to support laws requiring HPV vaccination for school entry if their state offers opt-out provisions. However, the study's lead author warned that such opt-out provisions may weaken the vaccine requirements' effectiveness.
A national survey found that 21% of parents support HPV vaccination requirements without opt-outs, increasing to 57% when opt-outs are included. Despite the vaccine's effectiveness in preventing cervical cancer, many parents lack knowledge and are hesitant to vaccinate their children.