Articles tagged with Asthma
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A new study found that kids with asthma who make 5 acute care visits have a 87% probability of future emergency department visits. Early treatment and controlled asthma management significantly reduce asthma attacks and ED visits.
A study by American College of Allergy, Asthma, and Immunology (ACAAI) found that patients who were told they had a penicillin allergy but tested negative could safely take the drug. Researchers examined records of 15 patients who received intravenous penicillin without adverse reactions.
Biologics target the cells and pathways that cause allergic inflammation linked to asthma. New treatments have improved breathing and reduced asthma attacks in people with severe uncontrolled asthma.
Two case studies illustrate how allergists can solve unexpected allergic responses, such as a woman with dry, chapped lips caused by kissing a corpse and another with chronic contact dermatitis from hair dye.
A new study found no significant difference in allergies between children who were breastfed and those formula-fed. The study examined 194 patients aged 4-18 years old with hay fever and similar numbers of kids with asthma, eczema, and food allergy.
A team of psychologists and engineers from SMU and the University of Maryland have received a $2 million NIH grant to create a wearable device for pediatric asthma patients that monitors air quality and identifies individual triggers. The device aims to alert patients before an attack, improving treatment outcomes.
A program combining home repairs, training, and comprehensive care significantly reduces childhood asthma symptoms and emergency department visits in low-income urban public housing. Removing asthma triggers such as mold and pests from these homes helps address the disproportionate impact of childhood asthma on minority communities.
Exposure to dogs or farm animals during a child's first year of life is associated with a lower risk of childhood asthma. Children exposed to these animals at age six had a significantly reduced risk of developing asthma.
A Swedish study found that children growing up with dogs have a lower risk of developing asthma, with a 15% reduction compared to those without dogs. The study analyzed over one million children and controlled for confounding factors.
Researchers found that adding a long-acting beta-agonist (LABA) to an inhaled corticosteroid (ICS) did not improve asthma control in black adults, contradicting national treatment recommendations. Genetic variants were also not associated with differential responses to therapy.
A Mayo Clinic study found stepping down daily asthma medicines can be done safely and at less cost for patients with stable asthma. Patients who stepped down their medicines saved an average of $34 per month compared to those who maintained the same level, without increased costs or reduced quality of life.
Researchers found that a 12-week supervised aerobic exercise program improved asthma control, reduced short-acting bronchodilator usage, and depressive symptoms in patients with confirmed asthma. The study suggests that aerobic exercise could be an adjunct to current pharmacological therapy for adult asthma patients with poor control.
A new study found that residents of green public housing experienced fewer 'sick building' symptoms and lower asthma outcomes compared to those in traditionally constructed low-income housing. The researchers also found improved indoor environmental quality, including better ventilation and reduced exposure to pollution sources.
A study published in BMJ Open Respiratory Research found that regular physical activity can significantly reduce asthma symptoms. The research, led by Concordia University, suggests that even moderate exercise such as walking or yoga can have a positive impact on asthma control.
Asthma and other allergies can be aggravated by artificial scents in hospitals, affecting vulnerable patients. Implementing a scent-free policy promotes patient safety and well-being.
Researchers at UBC and BC Children's Hospital found that acquiring four specific gut bacteria can protect infants from developing asthma. The study analyzed fecal samples from over 300 children and confirmed the finding in mice, opening the door to probiotic treatments for premature babies.
Researchers have developed an informatics platform to crowdsource data on pediatric asthma triggers, combining air quality and environmental exposure data with clinical information. The system aims to help doctors tailor recommendations for patients based on real-time pollutant exposure.
A new study found that grandmothers who smoked during pregnancy significantly increase the risk of asthma in their grandchildren. The research used data from the Swedish Registry and included over 44,000 grandmothers from 1982 to 1986. Asthma risk was increased by 10-22%.
Researchers have defined three distinct types of severe asthma using biological data, enabling the development of tailored drugs and improved treatment. The study's findings aim to provide personalized medicine for severe asthma sufferers.
A study by Mrs Lee Koh found that walking on side-street routes instead of main roads can reduce peaks in harmful air pollution. By avoiding busy streets, individuals can minimize their short-term and long-term exposure to black carbon particulate matter, a major component of urban air pollution.
A recent study by Mayo Clinic Children's Research Center found that kids with asthma who are exposed to secondhand smoke are twice as likely to be hospitalized for an asthma flare. The study analyzed data from over 430,000 children and strengthens the link between secondhand smoke exposure and increased asthma symptoms.
The American College of Physicians task force recommends counseling and pharmaceutical interventions to help adults and pregnant women quit smoking. Behavioral therapy or medications with FDA approval are recommended for nonpregnant adults, while pregnant women receive only behavioral interventions.
A major European study has identified key characteristics of severe asthma, which will help develop new treatments. Patients with severe asthma experience daily symptoms despite high doses of treatment and are more likely to be hospitalized.
Researchers analyzed data from Australia's 2006-2007 wildfires and found exposure to wildfire smoke was associated with increased hospital emergency department visits for asthma. Fine particulates in wildfire smoke are easily inhaled and remain deep in the lungs, causing harmful health effects.
Researchers at VIB discovered that exposure to farm dust reduces the severity of allergic reactions in mice. In humans, a deficiency in the protective protein A20 is found in those who suffer from allergies and asthma. The study paves the way for the development of an asthma vaccine.
Researchers identified three distinct groups of asthma patients characterized by different genes in airways, with Th2 and Th17 pathways reciprocally regulated. Blocking both pathways simultaneously may demonstrate better efficacy than targeting either alone.
A new article from the American College of Allergy, Asthma and Immunology recommends using epinephrine for all severe allergic reactions, regardless of symptom certainty. Experts stress that delays can have severe consequences, making epinephrine the most effective tool in combatting anaphylaxis.
Asthmatics are particularly sensitive to sulfur dioxide, which can cause airway irritation even at low concentrations. Scientists still don't know why asthmatics lack the ability to produce interleukin-10, a protein that stops inflammatory processes.
Researchers have discovered a stress pathway in immune cells that play a role in certain forms of asthma. The IRE1α/XBP1 pathway helps eosinophils, a type of immune cell implicated in asthma, develop and survive. This finding suggests a potential new therapeutic target for treating asthma.
A nationwide study finds that fine particulate matter, known as PM2.5, surge on July 4 due to fireworks, with concentrations 42% higher than usual on average. The study's results will help improve air quality predictions and raise awareness about the health risks of particle pollution.
Researchers from the University of Pittsburgh School of Medicine have discovered a unique immune response feature in patients with severe asthma, which may lead to new treatments. The study found that boosting levels of secretory leukocyte protease inhibitor (SLPI) reduces airway hyper-reactivity in animal models.
Researchers identified clusters where higher numbers of children who developed asthma were born in Toronto, suggesting early life factors at the neighbourhood level are relevant to childhood asthma. Air pollution during pregnancy and shortly after birth was found to be related to developing asthma later in childhood.
A recent UC Davis study highlights the need for improved primary care support structures to address high pediatric asthma rates in California. The research found that nearly 10% of state children suffer from asthma, with low flu vaccination rates and limited access to primary care providers contributing to these rates.
A new study found that older asthma patients, particularly those over 30, are more likely to experience treatment failure. The risk of treatment failure increases proportionally with age above 30 and is associated with lower lung function measurements and longer duration of asthma.
A study by the University of Arizona's BIO5 Institute has identified potential protective compounds in dust samples from Amish farming communities. The findings suggest that these natural environmental products could be transformed into medicines to promote lung health and prevent asthma. The research aims to understand the biological ...
Research suggests that aerobic exercise can curb asthma symptoms and improve quality of life by reducing bronchial hyperresponsiveness and inflammatory response. The study found significant improvements in symptom-free days, worsening symptom bouts, and quality of life scores among participants with moderate to severe asthma.
A Canadian study found weight loss reduced asthma severity by normalizing or improving airway hyperresponsiveness and quality of life in obese adults. The study supports treating comorbid obesity in individuals with asthma.
A study by researchers from the University of Seville found that high concentrations of fine particles (PM2.5) in urban areas increase hospital admissions for children with respiratory illnesses such as bronchiolitis, pneumonia, asthma, and bronchitis. Reducing PM2.5 levels to the recommended WHO threshold could lead to a daily saving ...
A new study from Northwestern University finds that soy supplements do not improve lung function for patients with asthma. Lifestyle and diet may play a role in managing the disease, rather than relying on individual strategies like increasing soy consumption.
A randomized trial of nearly 400 children and adults with poorly controlled asthma found that supplementation with soy isoflavone did not improve lung function or clinical outcomes. The study suggests that this supplement should not be used for patients with poorly controlled asthma.
A new school-based program helps reduce absenteeism among urban minority children with asthma. The program, called Building Bridges for Asthma Care, identifies children with inadequately controlled asthma and provides support to help manage their disease and stay in school.
Researchers at Johns Hopkins Medicine found that men with a history of asthma are 29% less likely to be diagnosed with lethal prostate cancer. Overall, asthmatic men were 36% less likely to die from the disease.
A new study found that nearly 22% of children with asthma also demonstrate a sensitivity to peanuts, which can lead to increased morbidity and mortality. The study suggests that peanut sensitivity screening may be beneficial for these children, especially when controlling wheezing and coughing is difficult.
A US study found that spirometry was underutilized for asthma diagnosis and management in adults from 2001 to 2011, despite national guidelines recommending its use. The test provides accurate measurements of air volumes and flows, playing a vital role in asthma diagnosis and management.
A new study suggests pharmacies can reduce asthma-related illnesses by dispensing more asthma controller medications. Pharmacies located in high utilization census tracts dispense more rescue medications than controller medications.
Researchers identified a genetic pathway linked to poor response to corticosteroid treatment in children with asthma. Targeting the VNN-1 pathway may offer new therapeutic strategies for difficult-to-treat patients.
Researchers created a model that predicts asthma-related emergency room visits with 75% accuracy by analyzing Twitter data and air quality sensors. The study highlights the potential of big data to address health challenges, particularly for chronic conditions like asthma and diabetes.
Researchers found asthma rates to be similarly high in urban Detroit and rural Georgia, contrary to the widely held theory that city life poses a risk factor. Poverty was identified as a common underlying cause of both conditions.
Researchers have identified a cellular receptor, CDHR3, for rhinovirus C, a cold-causing virus strongly associated with severe asthma attacks. A variant of the gene has been linked to an increased risk of childhood wheezing illnesses and asthma.
Researchers will investigate biophysical factors, environmental exposures and allergens associated with asthma control in older adults. The five-year study aims to develop interventions to improve symptoms, reduce emergency room visits and enhance overall well-being for seniors with asthma.
A study led by Massachusetts General Hospital investigators suggests that bariatric surgery can significantly reduce the risk of asthma attacks in obese patients. Significant weight reduction after surgery resulted in a half reduction in serious asthma-associated events, including emergency department visits and hospitalizations.
Researchers at Keck School of Medicine of USC have identified a crucial molecule in the survival of type 2 innate lymphoid cells, which trigger primary asthma symptoms. Targeting these molecules could lead to a cure for asthma or exacerbations caused by these cells.
Researchers found that teen girls from rural areas were more likely to have undiagnosed asthma, with a higher rate of depression among asthmatic teens. The study suggests that depression can be a barrier to diagnosis and treatment of the disease, making it essential to address this issue.
A new investigational drug, reslizumab, has been shown to reduce asthma attacks in patients who have difficulty controlling the disorder with standard medications. The study found that patients treated with reslizumab were at least 50% less likely to experience severe asthma exacerbations.
Research by Henry Ford Hospital reveals that breastfeeding and early exposure to bacteria stimulate the immune system, boosting protection against allergies and asthma. The study found distinct gut microbiome compositions in breastfed vs non-breastfed infants, with breastfed babies at lower risk of developing allergies.
A study published in Journal of Biological Chemistry identifies CCL28 as a key player in inducing asthma pathology even without a viral infection. This finding opens the door for developing potent and specific CCL28 inhibitors to prevent post-viral asthma in young children.
Researchers from INSERM have demonstrated gallopamil's clinical efficacy in treating severe asthma by reducing bronchial smooth muscle mass and airway obstruction. The study involved 31 patients with severe asthma, who showed significant improvements in BSM thickness and asthma attacks after treatment.
Researchers have identified over 30 genes with a strong impact on Immunoglobulin E, allergies, and asthma. These genes offer potential novel drug targets for treating these conditions, which affect 30% of the population.
Researchers at CU School of Medicine have identified Muc5ac, a protein involved in airway hyperreactivity, as a potential target for reducing obstruction in asthma. The study found that genetic removal of Muc5ac eliminated airway hyperreactivity, offering new hope for treating this chronic respiratory disease.
A recent epigenetic study has identified over 30 genes that predispose individuals to allergies and asthma, providing potential new drug targets. The research also found biomarkers that may predict which patients will respond to existing therapies.