Articles tagged with Asthma
A new study found that children with a history of food allergy are more likely to develop asthma and allergic rhinitis, with rates roughly doubling in those with peanut, milk, and egg allergies. The study analyzed data from over 1 million urban and suburban children.
Research suggests that genetic influences on asthma are more pronounced when exposed to early life environmental factors, such as viral respiratory infections. Children with a specific variant of the PAI-1 gene and a history of severe lower respiratory tract infections have an increased risk of developing asthma.
The National Institute of Allergy and Infectious Diseases has awarded BRI a five-year, $8 million grant to collaborate with UW Medicine and SCRI on immune system responses to allergens in the lungs. This study aims to inform new treatments for allergies and asthma.
A new study found that young children with mild, persistent asthma can tolerate acetaminophen without worsening their symptoms. The study, funded by the National Heart, Lung, and Blood Institute, compared acetaminophen to ibuprofen in 300 children aged 1-5 years old.
A study of 300 children with mild, persistent asthma found that acetaminophen was not associated with worsening asthma symptoms compared to ibuprofen. The results suggest that acetaminophen can be used safely in children with this condition.
A randomized trial led by Boston Children's Hospital found no difference between acetaminophen and ibuprofen in treating pain and fever in children with mild persistent asthma. The study enrolled 300 children aged 1-5 years old and showed that both medications were effective in controlling asthma symptoms.
A study led by the University of Leicester found that a new asthma pill called Fevipiprant significantly reduced symptoms and improved lung function. The drug was shown to decrease inflammation and repair airway linings, offering hope for severe asthma sufferers.
A new study finds that a child's home address can identify families at risk of severe asthma due to socioeconomic hardships. The address is linked to zip code and census data to target resource allocation.
A new study found that people with asthma living near larger or bigger fracking industry wells in Pennsylvania are 1.5-4 times more likely to experience asthma attacks. The researchers identified a significant increase in asthma attacks among patients living closer to these wells, particularly during the production phase.
A study of over 35,000 patients with asthma found that living near areas with high residential unconventional natural gas development activity was associated with a higher risk of asthma exacerbations. The study estimated air pollution and exposure metrics using distance, well characteristics, and phase duration.
Researchers at UW-Madison and Purdue University have solved the atomic structure of rhinovirus C, a cold virus linked to severe asthma and respiratory infections in children. The findings provide a foundation for future antiviral drug and vaccine development against the virus.
Researchers found significant differences in hospital practices for treating children with asthma, including varied costs and resource use. The study's template matching tool enabled a more refined comparison of hospitals' resource use at the patient level.
Researchers found a statistically significant 20% increase in childhood asthma cases exposed to the Great Smog in utero or early childhood. The study suggests a strong possibility of a causal link between early childhood exposure to air pollution and later development of adult asthma.
A new study by Children's Hospital of Philadelphia researchers found that Medicaid status has little effect on inpatient costs, length of stay, and use of intensive care units for children hospitalized for asthma. The study analyzed over 17,000 pairs of pediatric asthma patients from 40 major US children's hospitals.
Patients with asthma who use illicit drugs and have low socioeconomic status are at higher risk of requiring intensive care. Not adhering to prescribed asthma medication also increases this risk.
Researchers at the University of Queensland are testing a new drug that targets IL-33 protein to slow or reverse asthma development. The drug has shown promise in mouse model research published in the Journal of Allergy and Clinical Immunology.
Researchers have identified specific microRNAs that play a crucial role in inducing asthma, providing a potential new target for treatment. The findings suggest that regulating these miRNAs could represent a novel therapeutic approach for asthma.
Researchers at Carnegie Mellon University developed simplified patient-centered consent forms that were equally effective but more engaging than traditional lengthy forms. Video formats also improved comprehension, with participants reporting feeling more engaged in the consenting process.
Researchers developed a wearable system called Health and Environmental Tracker (HET) to monitor users' environment, heart rate, and other physical attributes to predict and prevent asthma attacks. The system uses novel sensing devices, including a spirometer, to track lung function and feed data into the system.
Research found that high arginine levels support metabolic pathways that reduce airway inflammation in asthma. Elevated arginine metabolism in human cells and mice improved mitochondrial function to offset inflammation.
Researchers at KARBio LLC and Genentech Inc. discovered that targeting human CRTh2 (hCRTh2) depletes immune cells implicated in asthma-associated inflammation, reducing cytokine production and lung inflammation in asthmatic mice. The study's findings support further exploration of hCRTh2 as a therapeutic target for asthma treatment.
A study of 417,494 older adults with COPD, asthma, or both found a significant increase in nontuberculous mycobacteria pulmonary disease among current and former inhaled corticosteroid users. Researchers identified fluticasone as a potential contributor to the increased risk.
Parents of children with asthma who experienced a teachable moment and received motivational smoking cessation counseling were more than twice as likely to quit smoking. Long-term in-home and telephone counseling also improved quit rates and reduced hospitalizations and missed school days due to asthma.
A study of 701 Canadian adults found that 30% of those diagnosed with asthma did not have current asthma after medication withdrawal. Careful testing revealed no evidence of airflow obstruction or bronchial hyper-reactivity in 37.5% of subjects.
Nearly half of patients with severe asthma had very poorly controlled symptoms over a decade, associated with comorbidities and poorer lung function. Persistent VPC asthma was linked to higher disease burden, compromised lung function, and lower medication adherence.
A study published in the New England Journal of Medicine found a link between persistent childhood asthma and chronic obstructive pulmonary disease (COPD) in early adulthood. Children with low lung function at a young age were more likely to develop COPD later in life, regardless of treatment or smoking exposure.
A nationwide clinical study aims to prevent and cure asthma in children at high risk, using a bacterial extract as treatment. The study enrolls over 1,000 babies from 6 to 18 months old and documents whether they develop fewer asthma symptoms than those receiving a placebo.
The Maryland Climate and Health Profile report highlights the state's vulnerability to climate change, with extreme weather events increasing the risk of foodborne illnesses, heart attacks, and severe asthma attacks. The report projects higher rates of these health issues in future decades, particularly among coastal communities.
Researchers found that increased asthma-related tweets correlated with higher rates of emergency department visits and hospitalizations. The study used real-time Twitter data to predict asthma emergencies, suggesting a potential tool for early intervention and prevention.
A University of Maryland School of Public Health study found that extreme heat and heavy rainfall increase the risk of asthma hospitalization in Maryland. The study showed a 23% increase in hospitalizations during summer months, particularly among children.
A study published in Annals of Emergency Medicine found that dexamethasone was effective in treating mild to moderate asthma in ER patients with only slightly higher relapse rates compared to a 5-day course of prednisone. The single-dose medication eliminates prescription adherence barriers such as forgetfulness and cost.
A new Cochrane Review suggests that yoga may have a beneficial effect on symptoms and quality of life in people with asthma. However, the effects on lung function and medication use are uncertain. Researchers found some moderate quality evidence that yoga exercise reduces the impact of asthma on people's quality of life.
A study found that a house dust mite immunotherapy tablet improved time to first moderate or severe asthma exacerbation when added to maintenance medications. The treatment reduced the risk of exacerbations and increased allergen-specific antibodies.
Researchers at Penn and Rutgers have identified a biological pathway that explains why current asthma therapies don't work well in many cases. The discovery highlights the potential for targeting non-inflammatory aspects of asthma, with neuropeptide Y emerging as a key player.
Researchers have identified a biological pathway in mice that explains the ineffectiveness of current asthma therapies. The discovery highlights the role of neuropeptide NPY in airway hyper-responsiveness and constriction. Inhibiting NPY activity may help alleviate asthma symptoms, providing hope for millions of patients.
Researchers at Penn State College of Medicine have identified new asthma biomarkers in blood that can predict asthma with 91% accuracy. The discovery may lead to the development of a diagnostic blood test and more targeted treatments for asthma.
Dr. Harissios Vliagoftis has been appointed as the GSK-CIHR Chair in Airway Inflammation, focusing on protease-activated receptor 2 (PAR2) research to help patients with asthma breathe easier. His work aims to develop biomarkers and treatments that can minimize discomfort and side effects.
A USC study found that improved air quality in the Los Angeles region has led to a significant reduction in respiratory symptoms among children, including bronchitic symptoms. The study tracked 4,602 children over 20 years and found a 16-32% decrease in these symptoms, even among those without asthma.
A study in Southern California found significant reductions in bronchitic symptoms among children due to decreases in air pollution levels. The analysis of 4,602 children aged 5-18 years revealed a proportional association between improved air quality and decreased respiratory issues, particularly among those with asthma.
A study published by the American College of Chest Physicians found that bronchial thermoplasty improves asthma quality of life for severe refractory asthmatics, regardless of their demographic factors. The procedure was shown to be effective in reducing resource utilization and improving patient outcomes.
A new study confirms the success of Boot Camp Translation, a patient-engagement method that translates complex medical guidelines into locally relevant language. The process has improved cancer testing, asthma management and hypertension control in various communities across the US.
A St. Michael's Hospital study found that women with low or high body mass indexes who smoked and drank had a two-fold higher risk of being diagnosed with asthma. The research included data from approximately 175,000 people aged 18 to 44 across 51 countries.
Asthma diagnosis has swung too far in the opposite direction, with inhalers prescribed for unnecessary reasons due to side effects such as growth suppression and increased risk of respiratory infections. Key findings highlight the need for accurate diagnosis using breathing tests and objective documentation.
Researchers at the University of Leicester have identified a new biochemical process that controls lung function and contraction during asthma. Disrupting this process can prevent airway narrowing and maintain normal lung function.
Research from Australia suggests that women with PCOS report a higher prevalence of asthma, which is also linked to excess weight. The study found that PCOS status and body mass index were independently associated with asthma.
A new study suggests that polycystic ovary syndrome (PCOS) is associated with asthma and excess weight in reproductive-age women. The research found a higher prevalence of asthma among PCOS patients compared to those without the condition, as well as an increased risk of asthma among overweight and obese individuals.
A new study from the University of Kansas suggests that a mother's increased vitamin D levels during the second trimester may lower her child's chance of developing asthma. The research found that increased sunlight exposure, which is where Americans get most of their vitamin D, reduces the risk of asthma in children.
A study of over 8,000 adults reveals that those with chronic health conditions are more likely to experience psychological distress and functional impairment if they live in poor or middle-income households. The findings highlight the importance of integrated care models to address physical and mental health concerns.
A study found that planned repeat C-sections are not associated with worse long-term health outcomes in children compared to vaginal births after cesarean sections. The only consistent difference was a slightly elevated risk for hospitalization with asthma in children born by C-section, but this was deemed clinically insignificant.
A new digital 'map' detailing different mechanisms contributing to asthma development could help researchers redefine the disease. The AsthmaMap allows personalized treatment by targeting specific asthma subgroups.
Researchers have identified a new target for treating asthma, finding that nociceptin reduces both immune response and airway constriction. This discovery offers a potential new approach to preventing or reducing established asthma attacks.
Researchers are developing a network of advanced sensors to detect particulate matter and pollen in metropolitan areas, providing real-time data for improved public health. The project aims to create an open-access platform for mapping pollution levels and supporting remediation efforts.
Researchers found a strong association between asthma symptoms and stress levels in teens, with waking up in the middle of the night and shortness of breath being key indicators. The study's lead author suggests that managing asthma is crucial for reducing stress and anxiety in young patients.
Pregnant women with asthma may be at greater risk of preterm birth due to exposure to high levels of traffic-related air pollutants like nitrogen oxides and carbon monoxide. Early exposure, particularly in the months leading up to conception and during early pregnancy, was found to increase preterm birth risk by nearly 30%.
Women with asthma experienced a significantly longer median total time to pregnancy (32.2 months vs 55.6 months) compared to those without asthma. Additionally, the birth rate was lower among asthmatic women, with fewer successful conceptions (39.6% vs 60.4%).
Research by the University of British Columbia found that babies born to mothers exposed to air pollution from traffic had a higher risk of developing asthma before age six. The study, which included over 65,000 children in Metro Vancouver, linked increased exposure to traffic-related pollutants with an increased risk of asthma.
Research found a consistent link between prenatal paracetamol exposure and asthma development, with the strongest association seen in children who had been exposed for multiple complaints. The study, the largest of its kind, also found no strong evidence for an association between maternal or paternal paracetamol use outside pregnancy.
A new study confirms that school reopenings are a primary driver of asthma exacerbations in children, with cold viruses being largely to blame. The research found a significant correlation between the timing of school starts and hospitalizations, highlighting the importance of preventive measures during peak viral transmission periods.
Babies born to mothers exposed to air pollution from traffic sources during pregnancy have an increased risk of developing asthma before the age of 5 years. Exposure to nitrogen dioxide and carbon monoxide, two markers of traffic-related air pollution, was found to increase this risk.
A new perspective article suggests a shift towards precision medicine, identifying 'treatable traits' in each patient to tailor management. This approach aims to improve patient outcomes by recognizing the clinical and biological complexity of airway diseases.