Articles tagged with Asthma
Researchers identified a genetic pathway linked to poor response to corticosteroid treatment in children with asthma. Targeting the VNN-1 pathway may offer new therapeutic strategies for difficult-to-treat patients.
Researchers created a model that predicts asthma-related emergency room visits with 75% accuracy by analyzing Twitter data and air quality sensors. The study highlights the potential of big data to address health challenges, particularly for chronic conditions like asthma and diabetes.
Researchers found asthma rates to be similarly high in urban Detroit and rural Georgia, contrary to the widely held theory that city life poses a risk factor. Poverty was identified as a common underlying cause of both conditions.
Researchers have identified a cellular receptor, CDHR3, for rhinovirus C, a cold-causing virus strongly associated with severe asthma attacks. A variant of the gene has been linked to an increased risk of childhood wheezing illnesses and asthma.
Researchers will investigate biophysical factors, environmental exposures and allergens associated with asthma control in older adults. The five-year study aims to develop interventions to improve symptoms, reduce emergency room visits and enhance overall well-being for seniors with asthma.
A study led by Massachusetts General Hospital investigators suggests that bariatric surgery can significantly reduce the risk of asthma attacks in obese patients. Significant weight reduction after surgery resulted in a half reduction in serious asthma-associated events, including emergency department visits and hospitalizations.
Researchers at Keck School of Medicine of USC have identified a crucial molecule in the survival of type 2 innate lymphoid cells, which trigger primary asthma symptoms. Targeting these molecules could lead to a cure for asthma or exacerbations caused by these cells.
Researchers found that teen girls from rural areas were more likely to have undiagnosed asthma, with a higher rate of depression among asthmatic teens. The study suggests that depression can be a barrier to diagnosis and treatment of the disease, making it essential to address this issue.
A new investigational drug, reslizumab, has been shown to reduce asthma attacks in patients who have difficulty controlling the disorder with standard medications. The study found that patients treated with reslizumab were at least 50% less likely to experience severe asthma exacerbations.
Research by Henry Ford Hospital reveals that breastfeeding and early exposure to bacteria stimulate the immune system, boosting protection against allergies and asthma. The study found distinct gut microbiome compositions in breastfed vs non-breastfed infants, with breastfed babies at lower risk of developing allergies.
A study published in Journal of Biological Chemistry identifies CCL28 as a key player in inducing asthma pathology even without a viral infection. This finding opens the door for developing potent and specific CCL28 inhibitors to prevent post-viral asthma in young children.
Researchers from INSERM have demonstrated gallopamil's clinical efficacy in treating severe asthma by reducing bronchial smooth muscle mass and airway obstruction. The study involved 31 patients with severe asthma, who showed significant improvements in BSM thickness and asthma attacks after treatment.
Researchers have identified over 30 genes with a strong impact on Immunoglobulin E, allergies, and asthma. These genes offer potential novel drug targets for treating these conditions, which affect 30% of the population.
Researchers at CU School of Medicine have identified Muc5ac, a protein involved in airway hyperreactivity, as a potential target for reducing obstruction in asthma. The study found that genetic removal of Muc5ac eliminated airway hyperreactivity, offering new hope for treating this chronic respiratory disease.
A recent epigenetic study has identified over 30 genes that predispose individuals to allergies and asthma, providing potential new drug targets. The research also found biomarkers that may predict which patients will respond to existing therapies.
A large-scale Danish study shows that premature babies are more likely to suffer from asthmatic symptoms and lung conditions in early life. However, the study found that they tend to grow better and eventually suffer no more lung conditions than others as adults.
A recent study by scientists at the University of Granada and the High Resolution Hospital in Loja reveals a moderate relation between asthma control and xerostomia severity. Inhaled corticosteroids (ICs) used to treat asthma can lead to dry mouth syndrome, which affects quality of life and mouth health.
Two UChicago research teams have received $1.7 million grants from the NIH to develop new treatments for sleep apnea and severe asthma. The projects focus on disrupting molecular processes to target breathing problems, with hopes to bring patients closer to life-changing medications.
A new study from Johns Hopkins Medicine reveals that urban living is not a significant risk factor for asthma, instead highlighting the importance of poverty, African-American race, and Puerto Rican ethnicity as potent predictors. The research found no differences in asthma rates between children living in urban areas and their suburba...
A large-scale study found rare genetic mutations in three genes (GRASP, GSDMB, and MTHFR) associated with asthma risk, but only in specific ethnicities. These findings suggest gaps in the current understanding of asthma genetics.
Participants with asthma had a higher risk of developing obstructive sleep apnea compared to those without asthma. Asthma duration was also found to be related to the development of new OSA and habitual sleepiness.
Researchers found that the common cold virus, rhinovirus, replicates more efficiently in cooler temperatures, such as inside the nose. The study suggests that lower body temperature impairs the innate immune response to the virus, making it easier for the virus to replicate.
A new UTMB study found that most patients using epinephrine autoinjectors incorrectly, with only 16% using the device properly. Inhaler users also made significant mistakes, with 63% missing three or more steps. Improving patient training is crucial to maximize medication effectiveness.
Scientists are exploring how bitter compounds cause airway constriction and searching for potential new treatments using a slime mould model. The study aims to identify cellular mechanisms that could reverse or prevent asthma attacks.
A new study by the University of Exeter Medical School found that residents in energy-efficient social housing may have a greater risk of developing asthma. The presence of mould doubled this risk, highlighting the need for residents to properly ventilate their homes to prevent health issues.
A new study published in the European Respiratory Journal suggests that toddlers who share a bed with their parents are more likely to develop asthma in later childhood. Researchers found an association between bed-sharing at two years old and increased wheezing symptoms in early childhood.
A senior GP argues that UK government plans to extend diagnosis targets in primary care to six other conditions are problematic and unscientific. The data on which they are based is flawed, leading to potential overdiagnosis and unnecessary tests and treatments.
Researchers at Karolinska Institutet have found no causal link between antibiotics and childhood asthma, contradicting previous studies. The study of half a million children suggests that respiratory infections may increase the risk of asthma, regardless of antibiotic treatment.
Research suggests respiratory infections play a key role in childhood asthma development. The link between paracetamol exposure and asthma is weakened when respiratory infections are considered.
Research found that people with asthma had a 27% higher incidence of Crohn's disease, while those with COPD had a 55% higher incidence compared to the general population. The study highlights the importance of early detection and treatment of bowel diseases in airway patients.
Research at Mayo Clinic reveals that patients with active asthma are at a twofold risk of having a heart attack. Patients with inactive asthma were not found to be at an increased risk, highlighting the need for better control of asthma symptoms and medication use.
Research studies presented at the American Heart Association's Scientific Sessions 2014 found that people with active asthma are more likely to experience a heart attack. Participants in the Multi-Ethnic Study of Atherosclerosis (MESA) who required daily medications for asthma were 60% more likely to have a cardiovascular event.
A new program has been shown to reduce asthma symptoms and hospitalizations in low-income children by training their parents over the phone. The peer coaching model, which was tested in a two-year trial, resulted in significant reductions in ER visits and hospitalizations among families with Medicaid insurance.
A new study suggests that individuals with more severe asthma may be more motivated to lose weight, making them a key target for intervention. Gender tailoring of weight loss programs could also enhance success rates among adults with asthma.
The University of Wisconsin-Madison will continue its Inner-City Asthma Consortium research with a $70 million, seven-year grant from the National Institute of Allergy and Infectious Diseases. The project aims to reduce asthma severity in inner-city children and develop effective treatments.
Asthma and chronic obstructive pulmonary disease (COPD) share similar symptoms, but the conditions have different causes and require unique treatment strategies. Accurate diagnosis is crucial to provide effective management for patients with overlapping characteristics of asthma and COPD.
A study found that household air pollution was twice as great in homes with children suffering from asthma and allergies. Volatile organic compounds also increased in these households.
A recent study by the American College of Allergy, Asthma and Immunology (ACAAI) found that teenagers with asthma have higher health literacy levels than their caregivers. Additionally, a study on YouTube videos for asthma control revealed that most popular videos provide low-quality information, while videos from healthcare providers ...
An allergic response to a medication for allergies can often go undiagnosed due to its initial purpose of reducing inflammation. Patients experiencing worsening symptoms or an unresponsive rash may be reacting to the medication itself or one of its components, such as antibiotics or antifungals.
A study found that adenotonsillectomy significantly decreased acute asthma exacerbations and episodes of status asthmaticus in children with asthma. The procedure may help alleviate underlying asthma severity by addressing related obstructive sleep apnea.
Researchers found that asthma patients who practiced shallower breaths and paired it with biofeedback significantly reduced their symptoms and improved lung function. The study also showed that this method can lead to better long-term lung health and reduced dependence on emergency medication.
Asthma is a widespread disease that causes genetic damage in peripheral blood, leading to oxidative stress and DNA damage. The study found four types of systemic effects, including protein damage, which can result in unstable chromosomes and increase the risk of other diseases.
A large study found that surgery for sleep apnea significantly improves asthma control in children, with a 30% reduction in acute asthma exacerbations and a 38% decrease in severe asthma attacks. The study suggests that early identification and treatment of obstructive sleep apnea may help reduce asthma severity and improve outcomes.
Researchers found that children hospitalized for asthma are nearly twice as likely to be rehospitalized if they live in areas with high housing code violations. Integrating housing data with health data can help target patients for medical interventions and improve healthcare delivery at the population and patient level.
Researchers found that Vitamin D-deficient asthmatics are at a higher risk of an asthma attack and that boosting levels may help manage acute episodes. The study analyzed medical records of nearly four million people and found significant immunomodulatory effects of Vitamin D on asthma.
A recent study found that asthma medications are associated with more and more serious adverse drug reactions in children, especially compared to clinical trials. The European ADR database shows a high share of serious ADRs in this population, highlighting the need for improved prescribing and monitoring practices.
Patients using medication for asthma/COPD, high blood pressure, or oral contraceptives often purchase cigarettes while filling prescriptions. Study data reveals a significant co-purchase rate of cigarettes with these medications, highlighting the need to prevent cigarette purchasing by individuals at greatest risk.
A study by Massachusetts General Hospital found that hospitals struggled to meet guidelines for asthma care, particularly those with weaker scientific evidence. The study suggests that overcrowding and crowding may contribute to the decline in meeting non-level-A recommendations.
The study found that Native American ancestry is associated with a lower asthma risk, while African ancestry is linked to a higher risk in Latino children. Lung function on average was also lower among children with greater African ancestry, even without asthma.
Researchers have identified a molecular mechanism that could explain why the common cold can bring on life-threatening asthma attacks. A small molecule called IL-25 may play a central role in triggering these attacks, and blocking it could potentially produce a much greater therapeutic effect.
A new OSU study found that using a gas stove with ventilation reduces the risk of childhood asthma, wheezing, and bronchitis. Children who lived in homes with ventilation were 32-44% less likely to have these respiratory issues.
Researchers at UTHealth will assess the asthma risk in healthcare workers in Texas over the last 10 years. The study aims to determine if changes in hospital practices and awareness have affected the prevalence of asthma among healthcare professionals.
Research found that workers experiencing high levels of job insecurity were more likely to develop asthma. The study, based on a German survey, indicates a potential link between psychological stress and new onset asthma.
Researchers found a 72% and 78% increase in childhood asthma risk among children exposed to butylbenzyl phthalate (BBzP) and di-n-butyl phthalate (DnBP), respectively, during pregnancy. Prenatal exposure to these phthalates can lead to inflammation and oxidative stress, increasing the risk of asthma.
A study found that combination therapy with long-acting beta-agonists (LABAs) and inhaled corticosteroids (ICSs) is associated with a lower risk of death or COPD hospitalization among older adults with COPD, particularly those with asthma. The therapy also showed promise for patients without asthma.
Researchers in Australia found that airborne dust particles stimulate inflammatory responses in airway cells, contributing to asthma development and worsening. The study suggests larger particles derived from dust may have important adverse effects on human health.
Research found that socioeconomic status significantly affects childhood asthma outcomes, with poor consequences concentrated among economically disadvantaged children. Family environment and parental stress play a crucial role in managing asthma, highlighting the need for social and emotional supports.
A new study found that people with asthma have a similar immune response to respiratory viruses as those without asthma, suggesting another aspect of the immune system is at play. The researchers compared the key immune response to viruses in the lungs and breathing passages, finding no significant differences.
According to a Northwestern Medicine study, only one in four students with asthma and half of children with food allergies have emergency health management plans in place at school. This underutilization leaves schools inadequately prepared to handle medical emergencies and puts the most vulnerable students at risk.
A study of over 13,000 men found that non-allergic asthma was significantly more common in children whose fathers smoked before conception. The risk of asthma increased with the duration and age of paternal smoking.