Indoor air pollution wreaks havoc on children's lungs
A study found that household air pollution was twice as great in homes with children suffering from asthma and allergies. Volatile organic compounds also increased in these households.
Asthma
Research on asthma and respiratory disease. Covers brain-structure links, prevention trials, weight-loss drugs, and exercise for symptom control.
Does father really know best? Maybe not when it comes to controlling asthma
A recent study by the American College of Allergy, Asthma and Immunology (ACAAI) found that teenagers with asthma have higher health literacy levels than their caregivers. Additionally, a study on YouTube videos for asthma control revealed that most popular videos provide low-quality information, while videos from healthcare providers ...
Asthma vs. COPD, similar symptoms -- Different causes and treatment
Asthma and chronic obstructive pulmonary disease (COPD) share similar symptoms, but the conditions have different causes and require unique treatment strategies. Accurate diagnosis is crucial to provide effective management for patients with overlapping characteristics of asthma and COPD.
Allergy sufferers are allergic to treatment more often than you'd think
An allergic response to a medication for allergies can often go undiagnosed due to its initial purpose of reducing inflammation. Patients experiencing worsening symptoms or an unresponsive rash may be reacting to the medication itself or one of its components, such as antibiotics or antifungals.
Genetic damage caused by asthma shows up in circulating blood stream, too
Asthma is a widespread disease that causes genetic damage in peripheral blood, leading to oxidative stress and DNA damage. The study found four types of systemic effects, including protein damage, which can result in unstable chromosomes and increase the risk of other diseases.
Surgery for sleep apnea improves asthma control
A large study found that surgery for sleep apnea significantly improves asthma control in children, with a 30% reduction in acute asthma exacerbations and a 38% decrease in severe asthma attacks. The study suggests that early identification and treatment of obstructive sleep apnea may help reduce asthma severity and improve outcomes.
Adenotonsillectomy and childhood asthma
A study found that adenotonsillectomy significantly decreased acute asthma exacerbations and episodes of status asthmaticus in children with asthma. The procedure may help alleviate underlying asthma severity by addressing related obstructive sleep apnea.
Asthma patients reduce symptoms and improve lung function with shallow breaths, more CO2
Researchers found that asthma patients who practiced shallower breaths and paired it with biofeedback significantly reduced their symptoms and improved lung function. The study also showed that this method can lead to better long-term lung health and reduced dependence on emergency medication.
Study recommends integrating housing data with health data to improve patient medical care
Researchers found that children hospitalized for asthma are nearly twice as likely to be rehospitalized if they live in areas with high housing code violations. Integrating housing data with health data can help target patients for medical interventions and improve healthcare delivery at the population and patient level.
Breathe easier: Get your D
Researchers found that Vitamin D-deficient asthmatics are at a higher risk of an asthma attack and that boosting levels may help manage acute episodes. The study analyzed medical records of nearly four million people and found significant immunomodulatory effects of Vitamin D on asthma.
Adverse drug reactions in children following use of asthma medications
A recent study found that asthma medications are associated with more and more serious adverse drug reactions in children, especially compared to clinical trials. The European ADR database shows a high share of serious ADRs in this population, highlighting the need for improved prescribing and monitoring practices.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalInternational Journal of Clinical Pharmacy·DateOct 27, 2014
Cigarette purchases, accompany prescription refills at pharmacies
Patients using medication for asthma/COPD, high blood pressure, or oral contraceptives often purchase cigarettes while filling prescriptions. Study data reveals a significant co-purchase rate of cigarettes with these medications, highlighting the need to prevent cigarette purchasing by individuals at greatest risk.
Study finds inconsistent achievement of guidelines for acute asthma care in hospital EDs
A study by Massachusetts General Hospital found that hospitals struggled to meet guidelines for asthma care, particularly those with weaker scientific evidence. The study suggests that overcrowding and crowding may contribute to the decline in meeting non-level-A recommendations.
SourceMassachusetts General Hospital·JournalJournal of Allergy and Clinical Immunology·DateOct 17, 2014
Asthma risk varies with ethnic ancestry among Latinos, UCSF team finds
The study found that Native American ancestry is associated with a lower asthma risk, while African ancestry is linked to a higher risk in Latino children. Lung function on average was also lower among children with greater African ancestry, even without asthma.
SourceUniversity of California - San Francisco·JournalJournal of Allergy and Clinical Immunology·DateOct 6, 2014
Study finds potential new target to treat asthma attacks brought on by colds
Researchers have identified a molecular mechanism that could explain why the common cold can bring on life-threatening asthma attacks. A small molecule called IL-25 may play a central role in triggering these attacks, and blocking it could potentially produce a much greater therapeutic effect.
Childhood asthma linked to lack of ventilation for gas stoves, OSU study shows
A new OSU study found that using a gas stove with ventilation reduces the risk of childhood asthma, wheezing, and bronchitis. Children who lived in homes with ventilation were 32-44% less likely to have these respiratory issues.
UTHealth researchers to assess asthma risk in health care workers
Researchers at UTHealth will assess the asthma risk in healthcare workers in Texas over the last 10 years. The study aims to determine if changes in hospital practices and awareness have affected the prevalence of asthma among healthcare professionals.
Job loss fears may boost first-time asthma risk
Research found that workers experiencing high levels of job insecurity were more likely to develop asthma. The study, based on a German survey, indicates a potential link between psychological stress and new onset asthma.
Phthalates heighten risk for childhood asthma
Researchers found a 72% and 78% increase in childhood asthma risk among children exposed to butylbenzyl phthalate (BBzP) and di-n-butyl phthalate (DnBP), respectively, during pregnancy. Prenatal exposure to these phthalates can lead to inflammation and oxidative stress, increasing the risk of asthma.
SourceColumbia University's Mailman School of Public Health·JournalEnvironmental Health Perspectives·DateSep 17, 2014
Combination therapy for COPD associated with better outcomes
A study found that combination therapy with long-acting beta-agonists (LABAs) and inhaled corticosteroids (ICSs) is associated with a lower risk of death or COPD hospitalization among older adults with COPD, particularly those with asthma. The therapy also showed promise for patients without asthma.
Long-term effects of childhood asthma influenced by socioeconomic status
Research found that socioeconomic status significantly affects childhood asthma outcomes, with poor consequences concentrated among economically disadvantaged children. Family environment and parental stress play a crucial role in managing asthma, highlighting the need for social and emotional supports.
Airborne particles beyond traffic fumes may affect asthma risk
Researchers in Australia found that airborne dust particles stimulate inflammatory responses in airway cells, contributing to asthma development and worsening. The study suggests larger particles derived from dust may have important adverse effects on human health.
Study sheds light on asthma and respiratory viruses
A new study found that people with asthma have a similar immune response to respiratory viruses as those without asthma, suggesting another aspect of the immune system is at play. The researchers compared the key immune response to viruses in the lungs and breathing passages, finding no significant differences.
Father's smoking prior to conception could increase asthma risk for baby
A study of over 13,000 men found that non-allergic asthma was significantly more common in children whose fathers smoked before conception. The risk of asthma increased with the duration and age of paternal smoking.
Input from a psychologist can help improve asthma symptoms
A new study suggests that addressing psychological needs can help alleviate severe asthma symptoms. The research found a 42% reduction in hospital days among patients who received psychological support after experiencing an asthma exacerbation.
Researchers improve severe asthma care through new, antibody-based treatment
Researchers developed an antibody-based drug, mepolizumab, to replace steroid-based treatments for patients with severe eosinophilic asthma. The new treatment has improved outcomes and reduced side effects in these patients, offering a more personalized approach to asthma care.
Too many kids with asthma, food allergies lack school emergency plans
According to a Northwestern Medicine study, only one in four students with asthma and half of children with food allergies have emergency health management plans in place at school. This underutilization leaves schools inadequately prepared to handle medical emergencies and puts the most vulnerable students at risk.
Sleeping on animal fur in infancy found to reduce risk of asthma
A new study found that sleeping on animal fur in the first three months of life may reduce the risk of asthma in later childhood. The research, presented at the European Respiratory Society International Congress, suggests that exposure to animal skin and fur could have a protective effect against asthma and allergies.
Flour identified as the main cause of occupational asthma in France
A new study in France has found that flour is the main cause of occupational asthma, affecting 20% of cases. The study also reveals higher incidence rates among skilled and unskilled workers, particularly those working in food product manufacturing.
Electronic nose can detect sub-groups of asthma in children
A new study found that an electronic nose can identify distinct sub-groups of asthma in children, differing in age and symptoms. This discovery may enable healthcare professionals to tailor treatment to each individual, improving diagnosis and outcomes.
Indoor mold poses health risk to asthma sufferers
A new study published in the Journal of Allergy and Clinical Immunology has found that indoor mold can lead to breathing problems and increase the likelihood of developing asthma. The research highlights the importance of adequate heating, ventilation, and home maintenance to reduce mold growth and its effects on health.
Rituals can help older people remember to take their asthma meds
A study found that storing medication in the bathroom and incorporating it into daily routines can improve adherence to prescribed inhalers. The research identified six strategies that aid elderly asthmatics in managing their condition, providing clinicians and care coaches with useful ideas to support patients.
Drugs used to treat lung disease work with the body clock
Scientists from The University of Manchester discovered that drugs used to treat asthma and pneumonia become ineffective due to the body's natural circadian rhythm. The study found that cells lining the lung airways have their own internal clock, which regulates inflammation in the lungs.
In asthma, it's not just what you smell, but what you think you smell
New research from the Monell Center reveals that believing an odor is harmful can lead to increased airway inflammation in asthmatics. Airway inflammation remained elevated 24 hours later, making asthmatics more sensitive to other triggers.
LJI develops new approach to identify genes poised to respond in asthma patients
A study by La Jolla Institute for Immunology identifies new genetic neighborhoods active in diseased cells, highlighting 33 genes that could be targeted with drug treatments. The research uses a novel approach to find specific genes associated with asthma, which may lead to more effective treatments.
Researchers uncover new knowledge about our intestines
Researchers have mapped 500 unknown microorganisms in human intestines and 800 bacteriophages that attack them. This new understanding could lead to more targeted treatments for diseases like type 2 diabetes, asthma, and obesity.
Deployment-related respiratory symptoms in returning veterans
A study of 50 returning veterans found that non-specific respiratory symptoms were common, with evidence of airway hyperreactivity in 36% of patients. Underlying mental health and sleep disorders were present in 66% of the patients. Airway hyperreactivity was seen in both asthma and nonspecific cases.
SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateJul 1, 2014
Genetic evidence that body mass increases the risk of asthma in mid-childhood
A study found that higher body mass index (BMI) and fat mass are associated with an increased risk of asthma in mid-childhood. The research, published in PLOS Medicine, used Mendelian randomization to assess the causal effect of BMI on childhood asthma.
Air pollution controls linked to lower death rates in North Carolina
A study by Duke University researchers found a strong association between improved air quality and declining death rates from emphysema, asthma, and pneumonia in North Carolina. The study analyzed data from 1993-2010 and found that reductions in sulfur dioxide, carbon monoxide, and fine particulates were significantly correlated with l...
Controlling ragweed pollen in Detroit: A no-mow solution for Motown?
A University of Michigan study found that occasional mowing creates conditions for ragweed to thrive, while leaving vacant lots unmowed reduces hay fever triggers. The researchers recommend regular or no mowing to reduce ragweed pollen exposure.
Mexican genetics study reveals huge variation in ancestry
A comprehensive genetic study of the Mexican population identified tremendous genetic diversity reflecting thousands of years of separation, explaining health factors such as differing rates of breast cancer and asthma. The study provides an explanation for misdiagnoses and incorrect treatment based on ethnic heritage.
Newborns exposed to dirt, dander and germs may have lower allergy and asthma risk
A new study confirms that children who live in homes with high levels of roach and mouse allergens and pollutants have higher overall allergy and asthma rates. However, those who encounter such substances before their first birthdays seem to benefit rather than suffer from them.
Early exposure to certain bacteria may protect toddlers from wheezing
A NIH-funded study found that early life exposure to specific combinations of allergens and bacteria protects against wheezing and allergic disease. The Urban Environment and Childhood Asthma (URECA) study revealed that cockroach, mouse, and cat exposure during the first year of life is associated with a lower risk of recurrent wheezing.
SourceNIH/National Institute of Allergy and Infectious Diseases·JournalJournal of Allergy and Clinical Immunology·DateJun 6, 2014
Common cholesterol drug greatly alters inflammatory response to common cold
Researchers discovered that statins can alter the inflammatory response to rhinovirus, a common cause of the cold, in individuals with asthma. This finding suggests that statins may help prevent or reduce asthma symptoms resulting from colds, and could lead to further research into novel asthma control strategies.
SourceFederation of American Societies for Experimental Biology·JournalJournal of Leukocyte Biology·DateJun 2, 2014
New study finds inhaler reminders dramatically improve asthma controller adherence
A new study found that reminders and feedback significantly improve medication adherence among asthma patients, leading to better asthma control. The study used an electronic inhaler monitor to track patient behavior and compared the effects of two interventions: daily reminders and personalized discussions with doctors.
Vitamin E in canola and other oils hurts lungs
A new Northwestern University study reveals that high gamma-tocopherol levels, found in soybean, corn, and canola oils, are associated with decreased lung function and increased asthma risk. In contrast, alpha-tocopherol, found in olive and sunflower oils, is linked to better lung function.
Higher health insurance cost-sharing impacts asthma care for low-income kids
Parents in low-income families with lower health insurance cost-sharing were less likely to delay or avoid taking their children to see a doctor. Many parents also reduced medication use and delayed visits due to financial stress, affecting their child's asthma care and control.
Intake of dietary methyl donors in the first trimester affects asthma risk in children
A study of over 1,000 mother-child pairs found that maternal intake of folate and other methyl donors during the first trimester was associated with a lower risk of childhood asthma. Only dietary vitamin B12 and choline were linked to reduced asthma prevalence.
Air pollution exposure in second trimester may increase asthma risk in children
A study found that exposure to particulate air pollution during the second trimester of pregnancy increases the risk of developing asthma in early childhood, particularly among non-obese mothers. The research suggests that timing of exposure may be crucial in understanding this relationship.
QVAR real-world study to be presented at annual ATS International Conference
A real-world study evaluating the benefit of treating asthma with small particle treatments like QVAR compared to larger particle treatments revealed interesting differences in asthma exacerbation outcome rates. The study found that initiating dosing with small versus large particle ICS treatments can impact asthma control rates.
Vitamin D supplementation does not improve asthma treatment, symptoms
A new study found that vitamin D supplementation did not reduce the rate of treatment failure or exacerbation of symptoms in adults with persistent asthma and low vitamin D levels. The study suggests that therapeutic vitamin D3 supplementation may not be an effective strategy for improving outcomes in patients with symptomatic asthma.
Study finds limited benefit for vitamin D in asthma treatment
Research at Washington University School of Medicine found that vitamin D supplements had a limited benefit for asthma treatment. Patients who achieved sufficient blood levels of vitamin D showed improved asthma control, including reduced treatment failures and asthma attacks.
Repeated preschool wheeze may set the stage for long-term damage in lung function
A new study found that repeated preschool wheezing can lead to long-term damage in lung function by the age of 6 years. Children with recurrent symptoms are particularly at risk, even if asthma symptoms seem to disappear temporarily. The study suggests that early intervention and treatment with inhaled corticosteroids may prevent this ...
UH Rainbow to study African-Americans' response to asthma medications
Researchers at UH Rainbow will evaluate treatment guidelines for African American children and young adults with asthma, exploring differences in response to asthma therapies compared to Caucasians. The study aims to identify the best add-on therapy based on patient age.
The Lancet and The Lancet Respiratory Medicine: Controlling, diagnosing, and preventing asthma
The Lancet and The Lancet Respiratory Medicine publish review articles on outdoor air pollution, asthma genetics, and preschool wheeze diagnosis to improve asthma control, prognosis, and personalized treatment approaches.
New discovery: Molecule links asthma and cancer and could aid in developing new treatments
Researchers discovered microRNA-10a regulates human airway smooth muscle cell growth and inhibits PI3 kinase, a master regulator of cell proliferation. This finding offers a new approach to treating both asthma-induced muscle thickening and cancerous tumor growth.
SourceFederation of American Societies for Experimental Biology·JournalThe FASEB Journal·DateMay 1, 2014
The key to easy asthma diagnosis is in the blood
A team of University of Wisconsin-Madison researchers has developed a faster, cheaper and more accurate tool for diagnosing even mild cases of asthma. The handheld technology uses neutrophil cell function in a single drop of blood to diagnose asthma.
SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateApr 15, 2014
Enzyme revealed as promising target to treat asthma and cancer
Researchers at Johns Hopkins Kimmel Cancer Center have identified SGK1 enzyme as a potential target for treating asthma and boosting the effects of certain cancer therapies. The enzyme's role in regulating immune system T cells suggests that blocking it could inhibit asthma symptoms and enhance cancer treatment.
Smoking bans cut premature births and childhood asthma attacks
Banning smoking in public places has been shown to cut premature births by 10% globally, according to a comprehensive study published in The Lancet. The research also found a 10% fall in hospital attendances for childhood asthma attacks in regions with anti-smoking laws.
Air pollution from traffic increases odds of hospital readmission for asthma
A new study finds that air pollution from traffic dramatically increases the odds of hospital readmission for asthma among white children. In contrast, black children were not found to have increased risk despite having higher rates of asthma readmission overall.
SourceCincinnati Children's Hospital Medical Center·JournalThe Journal of Pediatrics·DateMar 27, 2014