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Science News for April 15, 2014


How mothers help children explore right and wrong

A new study published in Developmental Psychology found that mothers' conversations with their children help them understand moral missteps and develop empathy. The study showed that these conversations have a significant impact on children's understanding of themselves as moral people, capable of both good and harm.

SourceConcordia University·JournalDevelopmental Psychology·DateApr 15, 2014

Drought hormones measured

Researchers at Carnegie Institution have developed a new method to measure abscisic acid levels in individual plant cells, shedding light on the hormone's role in plant stress responses. This breakthrough tool has the potential to improve crop yields and inform strategies for mitigating the impacts of drought and climate change.

Lifestyle determines gut microbes

Researchers analyzed the gut microbiota of Hadza hunter-gatherers, revealing a unique microbial profile that supports their adaptation to a foraging subsistence pattern. The study found differences in gut microbiota between sexes, reflecting sexual division of labor and having implications for fertility and reproductive success.

SourceMax-Planck-Gesellschaft·JournalNature Communications·DateApr 15, 2014

Can refined categorization improve prediction of patient survival in RECIST 1.1?

A recent analysis by the RECIST Working Group found that modeling target lesion tumor growth did not improve prediction of overall survival beyond other components of progression. The study also revealed that new lesions and non-target progressive disease were linked with worse overall survival in multivariate models.

SourceEuropean Organisation for Research and Treatment of Cancer·JournalEuropean Journal of Cancer·DateApr 15, 2014

Astronomers: 'Tilt-a-worlds' could harbor life

Research reveals that a planet's tilt can increase its habitability by reducing the likelihood of freezing over. The study expands the habitable zone by 10-20%, doubling the number of potentially habitable planets in the galaxy. This discovery opens up new possibilities for life beyond Earth and its neighbor planets.

SourceUniversity of Washington·JournalAstrobiology·DateApr 15, 2014

Osteoporosis risk heightened among sleep apnea patients

A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that obstructive sleep apnea raises the risk of osteoporosis, especially among women and older individuals. The study used data from Taiwan's National Health Insurance program to track 1,377 people with obstructive sleep apnea and comp...

SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateApr 15, 2014

Outcome of stroke worse for people with infection

A University of Manchester study reveals that infection after a stroke significantly worsens outcomes, with the immune system's response to the infection causing more damage. Researchers identified specific blood cells and molecules involved in this process, paving the way for potential anti-inflammatory therapies.

SourceUniversity of Manchester·JournalAnnals of Neurology·DateApr 15, 2014

Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works

Scientists have solved a decades-old medical mystery by understanding the mechanism of action of amphotericin, an antifungal drug that has been in use for over 50 years. The researchers found that most of the drug aggregates on the exterior of membranes, extracting sterols out of membranes like a sponge, leading to cell death.

The Lancet: Functional brain imaging reliably predicts which vegetative patients have potential to recover consciousness

A new study published in The Lancet found that functional brain imaging techniques, such as PET and fMRI, can reliably predict which vegetative patients have the potential to recover consciousness. The research suggests that these techniques can complement standard behavioral assessments to identify patients with a higher chance of lon...

SourceThe Lancet·JournalThe Lancet·DateApr 15, 2014

Outgoing behavior makes for happier humans

Research by Timothy Church at Washington State University found that extroverted behavior leads to more positive feelings and upbeat behavior in people from diverse cultural backgrounds. The study also showed that individuals feel more extroverted when given the freedom to choose their own behavior.

SourceWashington State University·JournalJournal of Research in Personality·DateApr 15, 2014

Researchers transplant regenerated esophagus

Researchers at Karolinska Institutet successfully transplanted a regenerated esophagus into rats, showing regeneration of nerves, muscles, epithelial cells and blood vessels. The breakthrough could improve survival and quality of life for patients with oesophageal disorders.

SourceKarolinska Institutet·JournalNature Communications·DateApr 15, 2014

UC research illuminates 'touchy' subject

Researchers at the University of Cincinnati have solved a century-long puzzle by proving that Merkel cells are the initial sites for sensing touch. Their study published in Cell journal shows that gentle touch triggers action potentials in Merkel cells, mediated by the Piezo2 receptor/ion channel.

SourceUniversity of Cincinnati·JournalCell·DateApr 15, 2014

Breakthrough points to new drugs from nature

Researchers at Griffith University's Eskitis Institute have developed a new technique for discovering natural compounds with therapeutic potential. The new screening process involves nuclear magnetic resonance (NMR) spectroscopy and has identified a potential lead in the fight against Parkinson's disease.

SourceGriffith University·JournalAngewandte Chemie International Edition·DateApr 15, 2014

New tool advances investigations of disease outbreaks

A new computational tool in Molecular Biology and Evolution helps public health officials investigate disease outbreaks by analyzing genomic data, correctly inferring source cases and transmission clusters. The tool complements traditional epidemiology methods, providing valuable insights into outbreak dynamics.

Breaking bad mitochondria

Hepatitis C virus infects liver cells' energy centers, damaging mitochondria and recruiting proteins to eliminate damaged area. This process helps the virus persist in the body, making mitochondrial operations a potential therapeutic target.

SourceUniversity of California - San Diego·JournalProceedings of the National Academy of Sciences·DateApr 15, 2014

Computerized counseling reduces HIV-1 viral load, sexual transmission risk

New York University researchers found that computerized intervention may aid antiretroviral therapy, improving ART adherence and reducing sexual transmission risk behaviors. The study, published in the Journal of Acquired Immune Deficiency Syndromes, showed a promising intervention for increased ART adherence and safer sex.

SourceNew York University·JournalJAIDS Journal of Acquired Immune Deficiency Syndromes·DateApr 15, 2014

New method isolates immune cells for researchers to study how they ward off oral diseases

Researchers at Case Western Reserve University have developed a new method to isolate single immune cells from the mouth, allowing them to study how these cells fight diseases. The method successfully isolated over 94% of the cells, enabling researchers to gain insights into treating oral cancers and other health issues.

SourceCase Western Reserve University·JournalBiological Procedures Online·DateApr 15, 2014

Study: SSRI use during pregnancy associated with autism and developmental delays in boys

A study of nearly 1,000 mother-child pairs found prenatal SSRI exposure was nearly 3 times as likely in boys with ASD relative to typical development. Exposure during the first trimester increased risk for autism spectrum disorder (ASD), while third trimester exposure elevated risk for developmental delays (DD) in boys.

Targeting cancer with a triple threat

Researchers have created nanoparticles that can deliver three or more different chemotherapy drugs to cancer cells, offering new hope for more effective treatments. The particles are designed to release the drugs in response to specific triggering mechanisms, reducing side effects and increasing efficacy.

SourceMassachusetts Institute of Technology·JournalJournal of the American Chemical Society·DateApr 15, 2014

Chrono, the last piece of the circadian clock puzzle?

A new circadian gene named Chrono has been discovered to function as a transcriptional repressor of the negative feedback loop in the mammalian clock. Mice lacking this gene exhibit longer circadian cycles, highlighting its importance in regulating daily rhythms.

SourceRIKEN·JournalPLOS Biology·DateApr 15, 2014

Groundbreaking nationwide study finds that people of color live in neighborhoods with more air pollution than whites

A groundbreaking nationwide study found that people of color are exposed to 38% higher levels of nitrogen dioxide outdoor air pollution compared to white people. The health impacts are substantial, with an estimated 7,000 deaths from heart disease among nonwhites each year if they breathed the lower NO2 levels experienced by whites.

SourceUniversity of Minnesota·JournalPLOS ONE·DateApr 15, 2014

In child custody disputes, LGBT parents face bias in the courts, new Drexel review finds

A new review from Drexel University finds that court decisions favoring heterosexual parents over gay or lesbian parents often ignore important social science research on parenting by gay and lesbian individuals. The researchers recommend considering this research to guide policy and inform judges' decisions in complex custody cases.

SourceDrexel University·JournalPsychology of Sexual Orientation and Gender Diversity·DateApr 15, 2014