Articles tagged with Asthma
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Research from the University of Adelaide found that pregnant women with asthma who smoke are at greater risk of complications, including preterm birth and low birth weight. The study suggests that quitting smoking during pregnancy can lead to some improvement in risks to the child.
A new University of Melbourne-led study found that heavy traffic pollution and wood smoke from heaters significantly worsen asthma symptoms in middle-aged adults. The study revealed a 80% increase in symptoms for those exposed to heavy traffic pollution and an 11% increase for those exposed to wood smoke.
Research from Boston University found that African-American women who reported frequent experiences of racism were more likely to develop adult-onset asthma. The study, which followed 38,142 women over 14 years, also discovered a significant link between increased racism and asthma incidence.
Researchers found that toll-like receptor 4 is activated by fibrinogen cleavage products, which are generated by proteinase enzymes. This activation leads to the production of pro-inflammatory cytokines and the recruitment of immune cells to the airways, resulting in asthma-like symptoms.
Researchers at LA BioMed discovered a link between maternal nicotine exposure during pregnancy and asthma in the third generation. The study found that even though the third generation was not directly exposed to nicotine or smoking, they were still more likely to develop asthma due to epigenetic modifications caused by maternal smoking.
Children's perceptions of living with asthma may differ significantly from those of their caregivers, a new study shows. The study found that both children and caregivers should be interviewed during doctor visits to ensure accurate understanding of the child's condition.
Researchers have discovered that a small protein chemokine called CCL26 plays a crucial role in the development and severity of asthma. CCL26 induces a greater migration of eosinophils in asthmatic airways compared to healthy volunteers, making it a potential target for new treatments.
A new study found that morbidly obese patients who underwent gastric bypass surgery experienced a decrease in the activity of genes tied to asthma, suggesting a potential link between obesity and asthma. The study also found higher concentrations of inflammatory compounds in obese individuals.
Researchers at VCU are studying the biology of allergic disease with a $1.8 million NIH grant. They aim to understand how mast cells respond to signals, potentially leading to new therapies for conditions like asthma and rheumatoid arthritis.
A new study found that children with higher genetic risks for asthma are not only more likely to develop the condition at a young age but also experience persistent symptoms in adulthood. Those with higher risk scores had poorer quality of life, missing work and school, and were hospitalized more often due to asthma.
A recent study suggests that genetic risk assessments could predict which children with asthma are likely to grow out of the condition. The analysis of data from a 40-year longitudinal study revealed that higher-risk genetic variants linked to asthma were associated with a greater likelihood of developing life-long-persistent asthma.
A research team at UCSF has found that exposure to nitrogen dioxide during infancy is strongly linked with later development of childhood asthma among African Americans and Latinos. The study indicates that traffic-related pollution might be a cause of the disease, calling for tightened U.S government standards for annual exposure to NO2.
A new study suggests that vitamin D deficiency may play a role in the increased allergy and asthma risk in overweight and obese adolescents. Researchers found significant correlations between the severity of obesity, adipokine levels, and biochemical measures of allergic disease.
Exercise-induced bronchoconstriction affects 10% of the population, causing symptoms like cough, wheezing, and shortness of breath. Vitamin C has been shown to halve the FEV1 decline caused by exercise in three randomized trials, indicating a potential benefit against this condition.
An Indiana University study found that a unique omega-3 supplement, Lyprinol/Omega XL, significantly improved lung function and reduced airway inflammation in asthmatics. The supplement, derived from the New Zealand green-lipped mussel, was effective in reducing symptoms and potentially improving athletic performance.
A study reveals a unique form of childhood asthma connected to impaired sphingolipid synthesis, bypassing typical allergen and inflammation pathways. This discovery may lead to precision medicine approaches for treatment.
A study of 170 parent-child dyads found that compromised lung function corresponded with poor sleep efficiency and impaired academic performance in urban schoolchildren. Family-level interventions aimed at asthma control and improving sleep quality may help improve academic performance in vulnerable populations.
A Phase IIa clinical trial found that dupilumab reduced asthma exacerbations by 87% and improved lung function, morning peak expiratory flow, and asthma symptoms. The study suggests dupilumab may be an effective treatment option for patients with persistent asthma.
A study found that exposure to nitrogen dioxide from traffic was associated with increased asthma severity levels in pregnant asthmatic women. The study used a sophisticated air pollution modeling system to assess community-level exposures, which were linked to higher risk of wheeze and asthma severity score.
A study suggests that early childhood respiratory infections, rather than analgesic use, may be driving the link between asthma and acetaminophen or ibuprofen. Researchers found a higher exposure to acetaminophen both prenatally and during infancy compared to ibuprofen.
Researchers found that purified ginger components can work synergistically with beta-agonists to relax airway smooth muscle and improve breathing. The most effective component was 6-shogaol, which dissolves F-actin filaments and inhibits phosphodiesterase4D.
Researchers have identified a potential new risk factor for obstructive sleep apnea: asthma. The study, which followed 1,500 participants over eight years, found that patients with asthma were 1.70 times more likely to develop sleep apnea. Childhood-onset asthma was associated with an even stronger link to sleep apnea.
A study published in Medical Mycology found that nearly 5 million asthmatics with allergic bronchopulmonary aspergillosis (ABPA) could significantly benefit from antifungal treatment. Clinical studies have shown a response rate of 60% with oral antifungal drugs, improving symptoms and asthma control.
The American Thoracic Society has released new official guidelines for the diagnosis and management of exercise-induced bronchoconstriction (EIB), a common condition affecting subjects with and without asthma. The guidelines provide practical guidance for clinicians, including treatment recommendations and preventive measures.
A study by Georgia Tech found that daily text messages about symptoms and asthma knowledge improved pulmonary function and understanding among pediatric patients with asthma. The results suggest that awareness and knowledge are crucial to proactive behavior, leading to better clinical outcomes.
A study by Harvard Medical School found that losing health insurance leads to poor asthma management among young adults, who are more likely to use emergency rooms and struggle with accessing medical care. The researchers emphasize the need for addressing social factors and creating transition plans from pediatric to adult care.
A study analyzing emergency admissions for asthma among adults in England found a significant annual 5% drop following the introduction of the country's smoking ban in 2007. The study, published in Thorax, confirms the value of public health interventions and attributes the association to reduced secondhand smoke exposure.
A recent study has identified a combination of genes and wheezing illness caused by human rhinovirus infection as a key predictor of childhood asthma. Children with a specific genetic variation and history of wheezing were nearly four times more likely to develop asthma by age 6.
Researchers found moderate evidence supporting the use of sublingual immunotherapy to improve asthma symptoms and decrease medication use by over 40% in treated patients. The treatment also showed promise for reducing symptoms of allergic rhinitis and conjunctivitis, with no reported episodes of anaphylaxis or death.
New research estimates that 14% of chronic childhood asthma is caused by exposure to traffic pollution near busy roads. The findings are comparable to the burden associated with passive smoking, highlighting the importance of clean air for all.
OzoneMap is a free mobile app that provides real-time air quality reports for the greater Houston area. It features a map of the city with colored clouds illustrating ozone levels, allowing users to select from three different maps and access information on health effects.
A new study confirms that children of mothers with obesity are four times more likely to experience frequent wheezing during the first 14 months of life. This finding suggests a potential intergenerational link between maternal obesity and asthma, highlighting the importance of weight management before pregnancy.
Researchers found that stimulating bitter taste receptors in some airway cells can lead to improved treatments for asthma attacks. Bitter substances act by shutting down calcium channels, allowing bronchodilation and ending the asthma attack.
A recent study published in The Lancet Respiratory Medicine found that a single inhaler therapy using beclometasone/formoterol combination is more effective in preventing asthma attacks than the traditional combination of corticosteroid and rapid-onset long-acting β2 agonist. This approach reduces hospital admissions and healthcare cos...
Researchers found an association between early childhood BPA exposure and elevated risk for asthma in young children. Post-natal exposure was associated with increased risk of wheeze and asthma, while BPA exposure during pregnancy had an inverse association with risk of wheeze at age 5.
Researchers identified a molecule called lipoxin A4 that plays a crucial role in resolving airway inflammation in asthma. This discovery provides new direction for developing next-generation asthma therapies to decrease chronic inflammation.
A new study investigates the role of protein kinase C (PKC) in airway smooth muscle contraction, revealing its potential as a therapeutic target for treating asthma and chronic obstructive pulmonary disease (COPD). The research suggests that PKC activation could contribute to airway hyperresponsiveness and exacerbate lung diseases.
Babies born by C-section are five times more likely to develop allergies when exposed to common allergens. The study suggests that early childhood exposure to microorganisms affects the immune system's development and onset of allergies.
Researchers found a once-a-month injection of omalizumab highly effective in treating teens and adults with chronic idiopathic urticaria. The treatment reduced symptoms by 53% after three months, offering a fast and safe alternative to antihistamines.
Research shows that asthma sufferers in the UK are putting their lives at risk by relying on short-acting bronchodilators instead of preventive medication. The main reasons for this behaviour include cost and stigma, with many young adults feeling embarrassed to use inhalers in public.
Researchers from Cardiff University have discovered hundreds of fungal particles in the lungs of asthma sufferers and healthy individuals alike. The study reveals that asthma patients have a distinct array of fungal species not present in healthy lungs, potentially leading to new treatment avenues.
A large study found that one in 20 cases of pre-eclampsia may be linked to increased levels of ozone during the first three months of pregnancy. Mothers with asthma are more vulnerable, and ozone exposure was associated with a higher risk of premature birth and pre-eclampsia.
New research reveals that exposure to air pollution and cockroach allergen early in life can increase the risk of developing an asthma-related cockroach allergy by age 7. Children with a common mutation in the GSTM gene are especially vulnerable to this increased risk.
A new study from Imperial College London found that cleaning jobs are strongly associated with an increased risk of developing asthma. Researchers tracked over 9,000 people born in Britain and found that nine percent developed asthma by age 42, with workplace risks responsible for one in six cases.
A new study found a substantial reduction in childhood asthma hospital admissions after the introduction of smoke-free legislation in England, with a 12.3% decrease in the first year. The law led to an equivalent of 6,802 fewer hospital admissions over the first three years.
A study of 7,500 British adults found strong links between jobs involving cleaning and cleaning agents and the development of adult asthma. Exposure to low-risk agents increased asthma risk by 20%, while high-risk exposure tripled it.
A study of 13,000 adults in Sweden, Norway, Denmark, Iceland, and Estonia found that plumbers and spray painters were at high risk of developing new-onset asthma due to workplace exposure. The study identified high-risk substances and occupations, highlighting the need for primary prevention measures.
Obese individuals are more prone to asthma due to the regulation of airway diameter by leptin. Leptin therapy may provide a new treatment option for body weight-associated asthma, with existing drugs targeting parasympathetic signaling already available.
The World Allergy Organization Journal is transitioning to BioMed Central's open access publishing platform, increasing global accessibility to allergy research. This move aims to improve knowledge-sharing and dissemination of research in the field of allergy, asthma, and clinical immunology.
People with asthma are at a higher risk of developing pulmonary embolism, with severe cases nearly 9 times more common than in the general population. Mild-moderate asthma increases the risk by 3.5 times, highlighting the importance of increased awareness and prevention among doctors
Asthmatic children in NYC asthma hotspots experience more frequent exercise-induced wheeze and ER visits than those in lower-asthma areas. Parents and physicians should be aware of the need for medication, such as bronchodilator inhalers, before exercise.
A new study by Boston University School of Medicine found that African-American women who suffered abuse before age 11 had a greater likelihood of developing adult-onset asthma. The study followed 28,456 women and found an increased incidence of asthma among those who experienced physical abuse during childhood.
The University of Texas Medical Branch at Galveston has received a five-year, $7.6 million grant to explore the role of respiratory viral infections and allergy in asthma development. Researchers will investigate four inter-related projects centering on airway inflammation and lung function.
A recent study published in Human Reproduction found that children born after infertility treatment have a higher risk of developing asthma. At the age of five, these children were two to four times more likely to experience asthma, wheezing, and take anti-asthmatic medication compared to those conceived naturally.
Research from USC finds that expectant mothers' beliefs about family roles predict higher birthweights and lower asthma rates in their children. The study suggests that cultural values can provide tangible physical health benefits.
A recent study published by the American College of Allergy, Asthma and Immunology suggests that pesticides used for water purification can lead to food allergies. The research found a correlation between high levels of dichlorophenol-containing pesticides and weakened food tolerance in individuals.
Researchers have designed new drugs that inhibit excess mucus production in airway cells, a major cause of death in respiratory conditions like asthma and COPD. The drugs target the MAPK13 protein, which is involved in the mucus pathway and can reduce mucus production by 100 fold.
Research linked health, housing, benefits, and education data for over 12,000 children, finding no detrimental effect of asthma on educational performance. Social adversity, mental health problems, and special educational needs were significantly linked to poorer test scores.
A study by University of Cincinnati researchers found that anxiety sensitivity significantly impeded the quitting efforts of smokers with asthma. Participants with higher anxiety sensitivity reported increased self-control as a motivation to quit, but also experienced temporary increases in anxiety symptoms, making it harder for them t...
A study of nearly 4,000 women found that respiratory symptoms like wheezing, shortness of breath, and cough change throughout the menstrual cycle, varying by body mass index, asthma, and smoking status. These patterns suggest a link between hormonal changes and respiratory symptoms through the menstrual cycle.