Research on diseases of the heart and blood vessels. Covers microvascular imaging, light exposure, cardiac imaging anxiety, and sex differences in risk.
A new study by the Cleveland Clinic found that consuming foods with erythritol increases the risk of cardiovascular events such as heart attack and stroke. The artificial sweetener makes platelets more active, which can raise blood clot risks. This research adds to evidence that erythritol may not be as safe as previously thought.
The American College of Cardiology has released a new guidance on managing patients hospitalized for heart failure, recommending tailored therapy based on clinical trajectory. The updated Expert Consensus Decision Pathway aims to improve disease management and reduce mortality.
A study published in Cardiovascular Diabetology found that higher blood glucose levels at admission significantly increase the risk of a poor functional prognosis or death within three months of an ischemic stroke. The study revealed that even a 10% increase in glucose levels raises the risk by 7%, and mortality risk by 88%.
A UofL cardiologist is leading a Phase II clinical trial of a new stem cell therapy for heart failure, the first in the US to use intravenous delivery. The trial aims to determine whether one or multiple doses of mesenchymal stem cells improve health and quality of life for patients.
A five-year randomized control trial found that diets high in fruits and vegetables lower blood pressure, reduce cardiovascular risk, and improve kidney health. The study also suggests that incorporating fruits and vegetables into treatment plans can be more effective than traditional medication approaches.
Researchers analyzed data from 63,700 patients in five clinical trials to understand the impact of clonal hematopoiesis of indeterminate potential (CHIP) on heart disease. They found that patients with CHIP had a 30% higher risk of initial heart attacks but not recurrent events.
A new study finds that higher levels of six urinary metals are linked to increased cardiovascular disease and mortality in a diverse US population. The findings support the role of urinary metals as novel risk factors for CVD and all-cause mortality.
Uncontrolled hypertension is a leading cause of premature death and disability worldwide, with 54% of patients aware but only 21% actively controlled. Effective treatment requires lifestyle changes and medication, as well as regular blood pressure monitoring to adjust doses accordingly.
A new analysis found that people hospitalized for heart disease, stroke, or cardiovascular diseases are 83% more likely to be diagnosed with anxiety, depression, or other psychiatric conditions within the first year after hospitalization. Early mental health screening and intervention are crucial for patients and their loved ones.
The paper explores evolving landscape of genetics research into obesity, emphasizing both new discoveries and challenges. Researchers highlight complexity of body weight regulation and advocate for precise phenotyping methods targeting relevant and refined phenotypes related to adiposity.
Researchers at the University Hospital Bonn have established a highly efficient and cost-effective way to generate functional endothelial cells from human induced pluripotent stem cells (hiPSCs) for tests in cell culture dishes. The new method delivers endothelial cells more quickly, requires fewer additives, and is highly reproducible.
The AHA PREVENT equations could reduce eligibility for statin and antihypertensive therapy among 15.8 million US adults due to lower atherosclerotic cardiovascular disease risk predictions. This change may impact treatment guidelines and recommendations.
Research at the University of Gothenburg shows that daily activities are insufficient to prevent strokes. Exercise in free time and active transportation significantly reduce stroke risk. The study suggests promoting public health policies encouraging physical activity to improve outcomes.
A recent paper surveys advances in diabetes pathogenesis and treatment, highlighting the role of genes, environmental factors, and social determinants. The study suggests that understanding these dynamics is key to developing targeted interventions to reduce diabetes risk and manage its complications.
A new University of Michigan study found that over 82% of Americans aged 50-80 take one or more prescription medications, with 80% open to stopping certain drugs. However, researchers stress the importance of personalized guidance for deprescribing older adults, particularly those taking medication for cardiovascular disease or diabetes.
An exploratory analysis associates current or previous use of antiretroviral drug abacavir with an increased risk of major adverse cardiovascular events (MACE) in people with HIV. The study, funded by the National Institutes of Health, found no elevated MACE risk for other antiretroviral drugs included in the analysis.
A study published in Circulation found that adults aged 50-54 with severely narrowed leg arteries had a higher risk of amputation after emergency surgery than those aged 80-84. This contradicts the traditional belief that older people are at increased risk.
A new study has identified CCL27 and TNFRSF14 as genetic markers in inflammation that may contribute to stroke recurrence. These findings could lead to novel drug targets to mitigate disability and mortality after a first stroke.
A nationwide study from University of Alabama at Birmingham compares two cardiovascular health metrics, Life’s Simple 7 and Life’s Essential 8, with the well-established Pooled Cohort Equation to determine their predictive values for mortality. The researchers found that PCEs outperformed LE8 and LS7 scores in mortality risk prediction.
A UC Riverside-led research team found that obesity causes chronic changes in the brain, leading to reduced connections between neurons and lower testosterone levels. The study suggests that the primary site of obesity's effects on reproductive function is the brain, rather than the testes or pituitary gland.
A new study published in Hypertension journal suggests that both 30-year and 10-year risk predictions should be considered when making high blood pressure treatment decisions. The researchers compared two risk prediction tools and found that long-term, 30-year risk may be more important than short-term, 10-year risk for informing medic...
A systematic review published in Nutrients highlights the positive health outcomes associated with pulse consumption. The study found that eating more pulses reduces the risk of type 2 diabetes and heart disease.
A recent study published in Nature Medicine confirms the health benefits of a diet high in unsaturated plant fats, such as the Mediterranean diet. The research used lipidomics to measure diet-related fat changes in the blood and link them to disease risk.
Researchers found increased liver oxidative stress and impaired antioxidant defenses in a DS murine model. The study suggests potential therapeutic strategies targeting oxidative stress and lipid metabolism to prevent or mitigate liver-related complications.
A study by Michigan Medicine found that older women over 65 who require complex heart surgery are more likely to be treated at low-quality hospitals, where they also die in greater numbers. The sex disparity in mortality doubled from high-quality to low-quality hospitals.
Research suggests that metabolically healthy obese individuals have a significantly lower risk of cardiovascular disease and death compared to those with metabolic unhealthy obesity. Fat distribution plays a crucial role in defining metabolic health, according to a recent review article.
Researchers at Wake Forest University School of Medicine have been awarded a five-year, $27 million grant from the National Institute on Aging to study the connections between heart health and brain health. The study will examine how cardiovascular disease contributes to Alzheimer's disease and other dementias.
A recent analysis found that nearly half of US counties lack a cardiologist, exacerbating rural-urban health disparities. Counties without cardiologists tend to be more rural, socioeconomically disadvantaged, and experience higher cardiovascular mortality rates.
A recent study found that for every same increase of BMI, fat mass and type 2 diabetes risk are increased in taller people. The authors hypothesize that the cardiometabolic risk of a higher BMI may be underestimated in taller grown populations worldwide.
A Swedish researchers have created a questionnaire test that quickly identifies individuals at high risk of heart attack. The test has been shown to be as accurate as blood tests and blood pressure measurements, detecting 65% of those at the highest risk of cardiovascular disease.
Cutting processed meat intake by 30% reduces the risk of diabetes, cardiovascular disease, and colorectal cancer. The study found that this reduction would lead to over 350,000 fewer diabetes cases and tens of thousands fewer cardiovascular disease and colorectal cancer cases.
Researchers found that facial temperatures are associated with chronic illnesses like diabetes and high blood pressure. They discovered specific regions of the face where temperatures correlate with age and health, including the nose, eyes, and cheeks.
An Italian study found that adherence to the Mediterranean Diet after a cancer diagnosis is associated with reduced mortality, especially from cardiovascular disease. Participants who followed a high-Mediterranean-Diet pattern had a 32% lower risk of mortality compared to those with lower adherence.
A new American Heart Association scientific statement highlights the benefits of palliative care in managing symptoms and improving quality of life for people with cardiovascular disease. Palliative care complements standard cardiovascular care by reducing physical symptoms, emotional distress, and assisting patients in making decision...
A new study found that strawberry intake significantly influenced flow-mediated dilation, suggesting a dose-response toward higher CVD risk reduction. The study also suggested a 8-times reduced CVD risk with daily strawberry consumption compared to the control group.
Between 2013 and 2023, private equity firms acquired 41 outpatient cardiology practices, corresponding to 342 clinic sites. The study highlights the critical need to monitor the effects of private equity acquisitions on quality of care and outcomes for patients with cardiovascular disease.
A six-year study found that consuming diets more closely aligned with the Mediterranean and DASH diets can lower levels of harmful blood markers and reduce cardiovascular disease risk. These dietary patterns emphasize plant-based foods, healthy fats, lean proteins, and low intake of processed foods and sugars.
Research from Michigan Medicine found that female patients with atrial fibrillation and tricuspid regurgitation are less likely to receive simultaneous procedures during cardiac surgery, despite guideline recommendations. This disparity may be related to perceived higher risk among women.
Black participants with greater access to green spaces had up to 35% lower odds of calcification, while those near a river had 32% lower odds. These findings highlight the potential benefits of environmental policies promoting public health and addressing racial and neighborhood-related health disparities.
Researchers at the Lewis Katz School of Medicine will investigate how injured heart cells communicate with other cells throughout the body using microvesicles known as exosomes. The study aims to understand how specific molecules, such as microRNAs, facilitate communication pathways between cells in the heart and vasculature.
Researchers discovered a step-by-step process of calcification in aortic valves, revealing two defense mechanisms: osteopontin and collagen fibers. The study provides new insights into understanding cardiovascular calcification and potential therapeutic applications.
Researchers found a 30% decline in UK coronary heart disease rates over two decades, but this was offset by rising rates of other cardiovascular conditions. The decline primarily benefited older age groups, with little improvement seen in younger or more deprived populations.
A study of over 4,500 healthy adults aged 60 and older found that nearly 28% had some form of heart valve disease, with age being the main risk factor. The majority of cases were mild, but the study highlights the need for more research into screening methods to identify and manage the disease in the elderly population.
The WVU researchers developed a non-invasive, at-home sleep apnea detection device that uses artificial intelligence technology to measure oxygen levels in the blood. Early detection can help prevent worsening of underlying comorbid conditions and reduce healthcare costs, according to Dr. Sunil Sharma.
Adults who consume more pulses show better diet quality and lower added sugar levels. Greater pulse intake is also associated with favorable weight-related outcomes and a reduced risk of elevated blood pressure.
Research from The Hospital for Sick Children found that certain subgroups of adolescents with depression have an even higher risk of developing CVD. The study identified four distinct groups of adolescents with depression, two of which demonstrated higher CVD risk, including a subgroup with dyslipidemia despite being healthy.
A cohort study of 10,634 participants reveals that childhood risk factors are associated with adult cardiovascular disease. The study highlights the importance of intervening in childhood to reduce the incidence of adult CVD, particularly for body mass index (BMI) and low-density lipoprotein cholesterol.
New research from Edith Cowan University found that dietary nitrate may play a role in preventing cardiovascular disease, dementia, and diabetes. Moderate to high intakes of plant and vegetable sourced nitrate were associated with a lower risk of all-cause, CVD-related, and cancer-related mortality.
Researchers found that hospitals that implemented standardized protocols from the American Heart Association and American Stroke Association saw significant reductions in stroke treatment times. The protocols, which include specific limits on time between symptom onset and hospital arrival, helped medical teams respond more quickly to ...
Researchers are exploring inflammation caused by COVID-19 as a trigger for Long Covid, a condition characterized by persistent symptoms like fatigue, brain fog, and shortness of breath. The study aims to identify potential causes and treatments for Long Covid, with findings that could lead to enhanced immune function in patients.
A new study reveals that micro- and nanoplastics may boost the risk of non-communicable diseases such as cancer, diabetes, and cardiovascular disease. The tiny particles are absorbed into the human body through food, air, and other sources, potentially leading to increased inflammation and severity of these conditions.
Researchers developed two clinical ageing clocks, PCAge and LinAge, that use blood tests, a urine test, and a health questionnaire to estimate future mortality risk. These clocks show significant predictive efficacy in characterising individual future ageing trajectories.
Researchers studied cancer survivors under 25 who had cancer since 1958 and found they were three times more likely to develop cancer later in life. Socioeconomic factors also played a role in survival rates, with lower education levels and foreign backgrounds increasing risk.
A study found that overexpressing a gene responsible for amino acid transport in the placenta can cause fetal growth to increase by 27%, while also providing insights into pregnancy complications like IUGR and obesity. The research has therapeutic implications, potentially informing treatments to prevent or treat these conditions.
Research published in the European Heart Journal found that women diagnosed with perinatal depression are more likely to develop cardiovascular disease. The study included data from around 600,000 women and found a strong link between perinatal depression and risks of high blood pressure, ischemic heart disease, and heart failure.
A new study published in JACC: CardioOncology found that air pollution significantly increases cardiovascular disease and mortality in cancer patients, contributing to health disparities. Short-term exposure to high pollution levels rapidly impacts cancer patients' cardiovascular health.
A recent study by the American College of Cardiology reveals significant disparities in cardiovascular care and mortality rates among Black Americans. The study found that Black Americans have suffered over 800,000 excess deaths due to higher cardiovascular disease death rates compared to White Americans.
Scientists have created mirror-image cyclodextrins in the laboratory, which could make it easier to formulate and deliver complex medications. These discoveries may also lead to improved treatment of cardiovascular diseases caused by atherosclerotic plaques.
A new study found that Americans are eating better, but disparities in diet quality persist among marginalized communities. The proportion of adults with poor dietary quality decreased from 48.8% to 36.7% between 1999 and 2020, while those with intermediate diet quality increased.
A cohort study found that more than 1 in 5 adults did not recover within 3 months of SARS-CoV-2 infection. The risk of recovery was lower among women and those with preexisting cardiovascular disease, but higher among vaccinated individuals during the Omicron variant wave.