Articles tagged with Cardiovascular Disease
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Scientists have created mirror-image cyclodextrins in the laboratory, which could make it easier to formulate and deliver complex medications. These discoveries may also lead to improved treatment of cardiovascular diseases caused by atherosclerotic plaques.
A new study found that Americans are eating better, but disparities in diet quality persist among marginalized communities. The proportion of adults with poor dietary quality decreased from 48.8% to 36.7% between 1999 and 2020, while those with intermediate diet quality increased.
A cohort study found that more than 1 in 5 adults did not recover within 3 months of SARS-CoV-2 infection. The risk of recovery was lower among women and those with preexisting cardiovascular disease, but higher among vaccinated individuals during the Omicron variant wave.
A new review paper explores the mechanistic links between peripheral vascular dysfunction, cerebral vascular dysfunction, and reduced brain health with aging. The study suggests that targeting fundamental aging mechanisms may be a promising strategy to reduce dementia risk.
Researchers have discovered a better way to identify those at high risk of potential heart attacks and strokes by adding genetic information to health checks. The study found that combining clinical risk scores with polygenic risk scores significantly improves identification rates, especially among younger people.
Zhen Yan and his team found thousands of molecular alterations in bodies after various durations of endurance exercise training, which have implications for human health. The study revealed that exercise can be a potent protection against diseases such as nonalcoholic fatty liver disease and inflammatory bowel disease.
The Pennington Biomedical Research Center is conducting a clinical trial to better understand lipedema. Participants will undergo comprehensive assessments and imaging techniques to help advance medical knowledge related to chronic disease. Compensation of up to $475 is offered for participation in the three-month study.
Research finds that Huntington’s disease damages microscopic blood vessels in the brain, affecting coordination between neuronal activity and oxygenation. The study uses non-invasive measurement techniques to monitor disease progression and evaluate potential treatments.
A new study led by Penn State researchers found that daily consumption of beetroot juice may improve blood vessel function and reduce future heart disease risk in postmenopausal women. Beetroot juice contains high levels of nitrate, which helps blood vessels expand and improves circulation.
A new risk equation could lead to a significant reduction in statin prescriptions, with 28.3 million adults potentially eligible instead of 45.4 million under current guidelines. The PREVENT equations incorporate recent insights into the biology of cardiovascular disease and remove race as a factor.
A cohort study found lower moderate to vigorous physical activity levels linked to increased cardiovascular disease or mortality in normoglycemic Hispanic and non-Hispanic adults. Adults with prediabetes may gain from reducing sedentary behavior and improving lifestyle factors beyond exercise alone
A recent study published in JAMA Network Open found a positive association between heavy lifetime cannabis use and cardiovascular disease mortality among female participants. The study suggests that long-term cannabis use may have negative effects on mortality rates, highlighting the need for further research.
A recent study from the Women's Health Initiative found that both obesity and metabolic syndrome increase breast cancer risk, but in distinct ways for different subtypes. The research highlights the importance of controlling waist circumference and metabolic conditions to reduce breast cancer risk.
A recent Cleveland Clinic-led study found that high levels of the sugar alcohol xylitol are associated with an increased risk of cardiovascular events like heart attacks and strokes. The research team identified a link between xylitol consumption and elevated platelet activity, which can lead to blood clots and thrombosis.
Research from the University of Illinois has found a link between per- and polyfluoroalkyl substances (PFAS) and cardiovascular diseases in postmenopausal women. The study reveals how PFAS chemicals interact with pro-inflammatory pathways, providing potential explanations for the increased risk.
By 2050, at least 61% of US adults (184 million people) are projected to have some type of cardiovascular disease, with total costs tripling to $1.8 trillion. Population shifts, high blood pressure, and obesity will drive this increase.
Researchers found a significant association between carpal tunnel syndrome and the risk of developing heart failure and amyloidosis. Individuals with carpal tunnel syndrome were at a 13% higher risk of heart failure and a threefold higher risk of amyloidosis compared to those without the condition.
A study by the University of Michigan Health Frankel Cardiovascular Center found that only 23% of heart attack patients received dietary counseling within 90 days of hospitalization. Nutrition counseling, often provided by registered dietitian nutritionists, may reduce cardiovascular risk for patients.
Two new studies show that people with narcolepsy have a significantly higher risk of cardiovascular disease and adverse cardiac events. The research found a 77% increased risk of any cardiovascular disease and an 82% increased risk of major adverse cardiovascular events.
Research reveals a three times greater risk for metabolic-dysfunction-associated steatotic liver disease in women with moderate-to-severe vasomotor symptoms compared to those with mild symptom severity. The study highlights the importance of addressing hot flashes and night sweats to assess cardiovascular health.
A new study reveals how accumulation of IMAT drives diseases such as muscle loss, type 2 diabetes, and cardiovascular disease. Regular exercise and healthy diet can prevent and reverse IMAT accumulation.
Researchers found that GLP-1 receptor agonists and SGLT-2 inhibitors lower the risk of major cardiovascular events, such as heart attacks, and severe liver complications compared to other diabetes treatments. These medications also showed no significant increase in severe adverse events.
A comprehensive study found that living with obesity for 10 years or more significantly increases the risk of heart attacks and strokes. The research, published at ENDO 2024, analyzed data from over 109,000 participants and revealed a 25-60% increased risk in younger adults.
A Korea University study reveals that gastrectomy decreases the risk of major adverse cardiovascular events in patients with gastric cancer. The research analyzed data from 2004 to 2013 and found a significantly lowered risk of cardiovascular disease in those who underwent gastrectomy.
Researchers found that 6% of patients with heart failure progressed to dialysis within a year, highlighting the need for integrating heart and kidney care. The study emphasizes prioritizing kidney function assessment in all patients with heart failure and promoting systemic changes to manage both conditions simultaneously.
A new study found that higher lifestyle scores associated with better heart health can lead to a younger biological age and lower risk of heart disease and stroke. The study used DNA methylation levels as a biomarker to estimate biological age.
A study of 2,814 men found that cardiovascular health in older age was worse for fathers compared to nonfathers, despite lower death rates. Fathers may have a more robust social support system and lower rates of depressive symptoms contributing to these findings.
A study found that statin therapy significantly reduces the risk of cardiovascular disease (CVD) and all-cause mortality in adults aged 60 years and older, including those over 85. Statins also did not increase the risk for adverse events such as myopathies and liver dysfunction.
The DRIVE-RM consortium, led by UMC Utrecht, aims to develop smart materials that assist the body in healing and regenerate tissues and organs using regenerative medicine. The project focuses on treating chronic diseases such as heart failure, kidney failure, and worn joints.
Research highlights varied associations between social isolation and mortality risk across demographic groups, including socioeconomic disparities. The study emphasizes the importance of considering sociodemographic heterogeneity in understanding the impact of social isolation on health outcomes.
Researchers at CU Anschutz Medical Campus identified key elements to improve diagnosis and treatment of coronary heart disease (CHD) in women, addressing the common misdiagnosis of heart attacks. The new guidelines provide recommendations to help clinicians better address sex-specific symptoms and treatments.
A large register-based study found that young adults with low stress resilience are more likely to develop psoriasis later in life. The study, based on data from over 1.6 million Swedish men, showed a significant link between stress resilience and the risk of developing severe cases of psoriasis.
A study of 14,399 women found that both step-based and time-based exercise targets were associated with lower risks of early death and cardiovascular disease. The research suggests that individuals should choose a goal aligned with their personal preferences rather than focusing on specific metrics.
A new American Heart Association scientific statement reveals significant gaps in the application of obesity research to patient care, with widespread adoption varying by healthcare professional and institution. The statement emphasizes the need for better implementation of evidence-based treatments and strategies, such as lifestyle mo...
Treatment with bisoprolol did not reduce self-reported COPD exacerbations, contradicting previous expectations. Researchers found bisoprolol effective for cardiovascular conditions but noted physician reluctance to prescribe it for COPD patients.
The Global Burden of Diseases study reveals a 49.4% increase in global disability-adjusted life years (DALYs) attributable to metabolism-related risk factors between 2000 and 2021. High blood pressure, high blood sugar, and high BMI are key contributors to poor health and early death.
A Danish-Spanish collaboration is launching the REACT initiative to develop early detection and prevention methods for atherosclerosis. The project aims to identify new means to detect atherosclerosis at earlier stages and at a younger age, enabling precision treatment and prevention.
Global life expectancy is forecasted to increase from 73.6 years in 2022 to 78.1 years in 2050, with a convergence of increased life expectancy across geographies. The trend is largely driven by public health measures that have prevented and improved survival rates from cardiovascular diseases, COVID-19, and other communicable diseases.
The IV-Lab project aims to develop a miniaturized, implantable multi-sensors device to monitor blood vessel health. The device will integrate multiple sensors measuring blood pressure, vessel deformation, and cardiovascular biomarkers, enabling timely and personalized treatment for patients with cardiovascular diseases.
A new study published in Journal of the American Geriatrics Society found that greater community mobility is significantly associated with better cognitive function in individuals aged 52 and older. The association was strongest among those at low risk for atherosclerotic cardiovascular disease.
A study published in Circulation found that revascularization significantly enhances the health-related quality of life (HRQoL) for patients with chronic limb-threatening ischemia. Patients who underwent endovascular intervention (Endo) showed slight statistical superiority over those who received surgical bypass (Bypass) in some HRQoL...
A review of 49 studies suggests vegetarian and vegan diets are associated with lower risk of cardiovascular diseases, cancer, and death. However, the authors note that remaining knowledge gaps must be addressed before making large-scale diet recommendations.
Scientists have developed a functional model of thoracic aortic aneurysm using human cells in laboratory rats, offering new avenues for drug development and effective screening. The model successfully mimics dilation of the human aorta and has potential applications for treating this potentially fatal condition.
Researchers at UC Santa Cruz discovered a secondary population of platelets that appears with aging, exhibiting hyperreactive behavior and unique molecular properties. This 'shortcut' pathway bypasses normal differentiation processes, producing problematic cells that can cause blood clotting diseases.
Scientists have discovered 17 new genes involved in clonal haematopoiesis, a process associated with ageing linked to increased risks of blood cancers. The findings highlight the clinical significance of these genes in driving mutant blood cell clones, offering new avenues for studying disease development and promoting healthier ageing.
Researchers found beneficial effects of Sacubitril/Valsartan in reducing inflammation, cardiac fibrosis, and preventing arrhythmias post-MI. The drug has shown promise in mitigating these effects and promoting healthier scar formation.
The 2024 AHA/ACC Guideline on the Management of Lower Extremity Peripheral Artery Disease aims to improve patient outcomes by emphasizing timely diagnosis and treatment. Coordinated care among a multispecialty team is crucial in reducing the risk of amputation, heart attack, stroke, and death for individuals with PAD.
A systematic review and meta-analysis found that low testosterone levels are associated with increased risk of all-cause mortality and cardiovascular death. Men with very low testosterone concentrations had a significantly higher risk of cardiovascular death, regardless of other hormone levels.
A plant-based diet is associated with a 47% lower risk of prostate cancer progression in men. Eating one or two extra servings of healthy foods daily can significantly reduce the disease's worsening chances.
Cardiovascular biomarkers strongly associated with cardiovascular events and mortality. Adding biomarkers to established risk factors improved heart failure and mortality prediction, but only slightly enhanced atherosclerotic disease risk prediction.
The V142I transthyretin variant is associated with substantial risk for heart failure hospitalization and death in Black individuals, particularly those with reduced ejection fraction. Further investigation into the complex interplay between the variant, ancestry, social determinants of health, and biological factors is warranted.
A genetic variant present in 3-4% of self-identified Black individuals increases the risk for heart failure and death. Carriers of the V142I variant are at significantly increased risk for heart failure beginning in their 60s, with an increased risk for death beginning in their 70s.
Researchers discovered that IL-6 signaling in CD4-positive T cells promotes pulmonary hypertension development and progression. Treating mice with IL-6 inhibitors improved symptoms and decreased damage to the lungs and heart.
The Academic Payvider model enhances value-based care by fostering improved coordination, reduced insurance hassles, and increased staff attention. This joint approach between payers and providers aims to drive complex care down through innovative reimbursement structures.
A study published in JAMA Pediatrics reveals that children diagnosed with hypertension are at a higher risk of major adverse cardiac events later in life. Improved detection, follow-up, and control of pediatric hypertension may reduce the risk of adult cardiovascular disease.
Researchers developed a non-invasive imaging technique to visualize cardiac micro-vessels in high resolution, enabling better understanding of cardiovascular diseases. The study improves diagnosis and treatment of conditions like microvascular coronary disease and cardiomyopathies.
Jeffrey W. Moses, MD, is recognized for advancing the field of interventional cardiovascular medicine through technical excellence and leadership. Dr. Moses has performed over 20,000 interventional procedures and made significant contributions to clinical research and educational activities in interventional vascular therapy.
Researchers found that over 130,000 people in Denmark live with atrial fibrillation, with a 20% increase in new cases each year. The study reveals heart failure is the most common complication, with a risk of death twice as high as stroke after diagnosis.
Menopausal hormone therapy is appropriate to treat vasomotor symptoms in early menopause without contraindications. WHI evidence does not support routine supplementation with calcium plus vitamin D or a low-fat diet for preventing fractures and breast/colorectal cancer, respectively.
Researchers found that cranberry extracts can stimulate beneficial bacteria in the gut, reducing inflammation and improving the prognosis of chronic diseases. The study suggests that cranberries may be a useful addition to a balanced diet in preventing or managing conditions like diabetes and cardiovascular disease.