Articles tagged with Cardiovascular Disease
A new study published in the Journal of the American Heart Association found that older women who sat for 11.7 hours or more per day increased their risk of death by 30 percent. The study used machine-learned algorithm CHAP to examine total sitting time and length of sitting bouts.
The new guidelines recognize the aorta as an independent organ, bundling its treatment with other specialties. This holistic approach improves treatment outcomes for patients with aortic rupture and other serious diseases.
A modelling study suggests that mandatory menu calorie labelling in England could prevent approximately 730 deaths from cardiovascular disease between 2022 and 2041. If extended to all food businesses, this number could increase to around 9,200 deaths.
A new study found that frequent cannabis use is associated with a higher risk of heart attack and stroke, even after controlling for tobacco use and other cardiovascular risk factors. The study analyzed data from over 430,000 adults in the US and found that smoking cannabis was significantly linked to cardiovascular risks.
A new American Heart Association scientific statement highlights the value of AI technology in improving cardiovascular disease patient outcomes. Despite its potential, AI applications face gaps and challenges, including robust clinical validation and addressing biases.
A study analyzing ELSA data found that osteoporosis, heart disease, and poor hearing increased frailty risk in men, while high fibrinogen levels, diabetes, and stroke were linked to higher risks in women. This highlights the importance of gender-specific action plans and intervention for older people.
Researchers identified six blood biomarkers associated with increased cardiovascular risk in patients with rheumatoid arthritis. These biomarkers improved the ability to predict arterial inflammation, an indicator of cardiovascular risk, compared to standard clinical indices.
New research reveals women's cardiovascular disease risks differ by age, lifestyle factors, and mental health conditions. Studies show sedentary behavior increases risk of death from all causes, while preeclampsia is linked to diet, highlighting need for targeted prevention strategies.
A recent Mayo Clinic study found that daylight saving time has a minimal impact on heart health. Researchers analyzed data from 36 million adults and found a slight increase in cardiovascular events during the spring and fall transitions, but this was deemed clinically insignificant.
Canadian healthcare leaders call for re-establishment of a national hypertension control program to reduce deaths and disabilities. The program aims to provide population-scale prevention methods, proven to save lives and reduce healthcare costs. Experts highlight the need for collaboration with governments and healthcare providers.
A new study finds that everyday discrimination can drive unhealthy coping behaviors like smoking, leading to increased heart disease risk. Research highlights the importance of considering multiple identities when studying health disparities and creating interventions.
Researchers developed scSNV-seq to investigate genetic changes affecting gene activity and disease development. The technique accurately assesses the impact of thousands of DNA mutations in cells, providing crucial insights for developing targeted therapies.
A recent study from Brigham and Women's Hospital found that a glycan biomarker of IgG is an important predictor for cardiovascular diseases. The research team discovered that the sugar coatings on IgG were directly related to the risk of a CVD event, most likely through inflammatory effects.
A study found that 2-methylbutyrylcarnitine (2MBC), a gut microbial metabolite, exacerbates thrombosis and is accumulated in COVID-19 patients. Elevated 2MBC levels are associated with increased blood clot risk, suggesting a potential mechanism linking gut microbiota dysbiosis to cardiovascular disease.
The Almodóvar lab is studying the link between HIV and pulmonary hypertension, a condition that increases pressure in lung arteries. By examining the interactions between different cell types and using a humanized mouse model, researchers hope to propose novel therapies to prevent lung diseases in people with HIV.
A new study reveals that genetic variants associated with hypertension can increase the risk of high blood pressure from as early as three years old. By analyzing health data from large population studies, researchers found that these genetic factors can significantly affect blood pressure levels throughout life and even beyond adulthood.
A Swedish study of over 9,000 men found that those who were physically fit in adolescence had a lower risk of atherosclerosis nearly 40 years later. The researchers used advanced imaging technology to examine plaques in the coronary arteries and found associations with both good cardiorespiratory fitness and muscle strength in youth.
A new study found that chronic exposure to PM2.5 is associated with increased risk of hospital admission for various cardiovascular conditions, particularly ischemic heart disease and cerebrovascular disease. The study suggests that lowering annual average PM2.5 levels could decrease overall cardiovascular hospitalizations by 15%.
A one-year interdisciplinary therapy program reduced inflammation and cardiometabolic risk in obese adolescents, improving insulin resistance and weight management. The semi-intensive model produced better results than previous intensive models, reversing hyperlipidemia and promoting energy balance.
New research from the University of California San Diego found that men with a higher area of abdominal muscle have a greater risk of cardiac trouble. Men with the densest muscle in their abdominal cavity had about one quarter the risk of coronary heart disease later on.
A new study found that severe maternal grief, particularly the loss of a partner or child, is associated with an increased risk of heart failure in children up to middle age. The research suggests that prenatal stress may lead to adverse changes in mental and physical health, impacting fetal heart development.
A study published in PLOS ONE found that raised blood pressure has been the leading risk factor for death in Australia for three decades, contributing to at least 44% of cardiovascular disease (CVD) deaths. The research highlights the importance of prioritizing blood pressure control efforts in public health agendas.
A new study suggests that finasteride, a common hair loss and prostate drug, may also lower cholesterol levels and reduce cardiovascular disease risk in men. In mice, the researchers found significant correlations between finasteride use and lower cholesterol levels, as well as reduced inflammation and atherosclerosis progression.
Researchers discovered that consuming over 22% of daily calories from protein can lead to increased activation of immune cells contributing to atherosclerotic plaque formation. Leucine, an amino acid found in animal-derived foods, plays a disproportionate role in driving pathological pathways linked to atherosclerosis.
A recent study by Cleveland Clinic researchers discovered a connection between elevated niacin levels and an increased risk of heart disease. The study found that high levels of 4PY, a breakdown product from excess niacin, were strongly linked to the development of heart attacks and strokes.
A major new study reveals that heart attack survivors are at high risk of developing further serious health conditions, including heart failure, kidney disease, and depression. The research found that up to a third of patients developed heart or kidney failure, and 38% died within nine years.
Rats fed high-fructose diets exhibit disturbances in autonomic nervous and cardiovascular systems, increasing risk of chronic diseases like diabetes and obesity. Fructose consumption by parents is also associated with impaired physiological regulation of their offspring's cardiovascular system.
A new American Heart Association scientific statement emphasizes the need for increased awareness of heart disease as a major health risk for women, particularly those with pregnancy complications. Early detection and treatment of risk factors may help prevent future heart attack, heart failure, and stroke.
The new advisory highlights the dramatic advances in understanding and treatment of cardiovascular diseases over the past century. These advancements have saved millions of lives and reduced heart disease death rates by more than half since 1950.
A new study found that physical activity levels are insufficient to counter the increased risk of cardiovascular disease associated with consuming sugar-sweetened beverages. Even moderate consumption can lead to higher cardiovascular disease risk, emphasizing the need to limit these drinks' omnipresence in the food environment.
Researchers have developed a new gene mapping technique that reveals how genetic alterations in cells lining blood vessels contribute to coronary artery disease. The technique, called Variant-to-Gene-to-Program (V2G2P), identifies biological mechanisms driving CAD risk by linking genetic variants to gene expression and function.
A recent analysis found a strong link between air pollution and mortality from cardiovascular diseases worldwide. In low-income countries, household air pollution caused significantly more stroke-related deaths than outdoor air pollution.
Researchers discovered that women with high-risk HPV infection have a significantly increased risk of blocked arteries, heart disease, and stroke. The study highlights the importance of monitoring cardiovascular health in patients with high-risk HPV, particularly those with obesity or other risk factors.
A new study published in the American Heart Association journal Hypertension found that tirzepatide significantly lowered systolic blood pressure levels in nearly 500 adults with obesity. The results suggest treating obesity with this weight loss medication may be an effective strategy for preventing or treating high blood pressure.
A five-year study shows that bariatric surgery maintains normal blood pressure levels without medications, while reducing BMI compared to medical therapy alone. Participants who underwent bariatric surgery had fewer medications and lower blood pressure rates than those on medication alone.
Researchers have discovered a new treatment that enhances the body's natural defences against atherosclerosis in patients with rheumatoid arthritis. Treating arthritic mice with RvT4 reduces blood vessel inflammation by re-programming macrophages to release stored lipids.
A study published at the American Stroke Association's International Stroke Conference 2024 found that treating people with ischemic stroke with intravenous injections of a combination of biologically active components of ginkgo biloba during the first two weeks after the stroke improved early cognitive recovery. The treatment, called ...
A new study found that abdominal aortic calcification is associated with rapid weight loss in older women, leading to higher risks of falls, fractures, and mortality. The researchers hope this discovery will lead to changes in treatment approaches for rapid weight loss in older adults.
The American Heart Association has outlined three target needs for improving cardiac arrest outcomes by 2030: increasing bystander CPR rates, defibrillation, and survival after cardiac arrest. The goal is to double survivorship to 20% through increased access to lifesaving care in underrepresented communities.
A study has found that sclerostin plays a beneficial role in reducing arterial calcification and promoting cell survival in patients with type 2 diabetes. The protein's cardioprotective function may have significant implications for therapeutic strategies in this patient population.
A international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The standout biomarker was N-terminal pro b-type natriuretic peptide (NT-proBNP), which is currently used to monitor heart failure status in patients.
A recent survey found that 51% of Americans are unaware that heart disease is the leading cause of death in the US. This lack of knowledge can be deadly, with nearly half of adults having some form of cardiovascular disease.
A study combines retinal imaging, genetics, and big data to estimate the likelihood of developing eye and systemic diseases. The researchers identified significant associations between retinal layer thickness and increased risk of various diseases, including ocular, neuropsychiatric, cardiac, metabolic, and pulmonary diseases.
New research confirms a concerning trend erasing a decade of progress in reducing mortalities from heart disease and stroke. The US cardiovascular disease death rate rose by 9.3% from 2020 to 2022, with over 228,000 more CVD deaths than expected if pre-2020 trends continued.
The study found that APOE4 carriers have elevated LDL cholesterol levels, increasing their risk of developing subclinical atherosclerosis. In contrast, APOE2 carriers have lower cholesterol and reduced atherosclerosis prevalence.
Research finds that stable caregiver relationships in childhood may increase optimal heart health, while adversity and abuse can lead to poor cardiovascular health. Lower income as an adult may also introduce additional adversity, making the relationship between caregiver-child adversity difficult to see.
Research reveals that stable and supportive caregiving during childhood can protect cardiovascular health later in life, contrary to previous findings on childhood adversity. The study analyzed over 2,000 participants and found that each additional unit score of caregiver warmth was associated with 11.7% higher odds of cardiovascular h...
A new study by UCL researchers found that financial stress is detrimental to biological health, disrupting the communication between immune and neuroendocrine systems. This can lead to disease, including cardiovascular disease, depression, and schizophrenia.
A study of 481,000 individuals found that those who predominantly sit at work had a higher risk of all-cause and cardiovascular disease mortality. Engaging in an additional 15-30 minutes of physical activity per day could help reduce this risk to levels similar to those who don't sit
A study published in Science Advances identifies a mitochondrial protein called MCJ as the first therapeutic target to preserve cardiac function in pulmonary hypertension. Modulating MCJ levels can activate a signaling pathway essential for adaptation to low oxygen levels, protecting the heart.
Participants with diabetes remission had a 33% lower rate of CKD and a 40% lower rate of CVD compared to those without remission. The magnitude of risk reduction was greatest for participants with longer-term remission.
Researchers developed an AI-driven algorithm that accurately predicts death and complications after percutaneous coronary intervention (PCI). The tool uses patient feedback to provide a patient-centered, individualized risk prediction score.
Researchers at Iowa State University found that a combination of aerobic and resistance exercises reduces cardiovascular disease risks as much as aerobic-only regimens. The study, which involved 406 participants, showed significant decreases in body fat percentage across all exercise groups compared to the no-exercise control group.
A new study found that young adults who reported higher stress as adolescents were more likely to have high blood pressure, obesity, and other cardiometabolic risk factors. This highlights the importance of stress management from an early age to prevent these health issues.
Chronic kidney disease and cardiovascular disease significantly worsen prognosis for severely burned patients. The study analyzed data from 1,193 patients and found that nearly half did not survive their burns with impaired kidney function. Researchers highlight the need to integrate these findings into burn treatment scores.
This special issue highlights promising research projects developing scalable digital technology solutions for improved heart and brain health. Smartphone-based assessments and point-of-care echocardiography have shown promise in diverse populations, including those with latent rheumatic heart disease and dementia.
Researchers have shown that combining poverty with chronic inflammation worsens health outcomes, increasing heart disease and cancer mortality rates. The study analyzed data from nearly 95 million adults and found a synergistic effect of poverty and inflammation on mortality.
Rheumatoid arthritis patients who underwent a single session of aerobic exercise experienced temporary reductions in blood pressure at rest and under stress. The study, conducted at the University of São Paulo, demonstrates the benefits of moderate-intensity walking for cardiovascular management and blood pressure control.
UAB researchers have created a 3D, three-layer nanomatrix vascular sheet that mimics human atherosclerosis, enabling high-throughput drug screening. The model replicates key features of the disease and has been validated with two classic atherosclerosis drugs.
Researchers found a decade-long decline in blood lead levels among American Indian adults was correlated with long-term cardiovascular health benefits, including reduced systolic blood pressure. The study suggests that even small decreases in blood lead levels can have meaningful health outcomes.