Articles tagged with Cardiovascular Disease
A new study from Tulane University found that walking more than five flights of stairs daily can cut the risk of heart disease by 20%. The study, published in Atherosclerosis, used UK Biobank data from 450,000 adults and found that stair climbing reduced cardiovascular disease risk in those with multiple risk factors.
The American Heart Association calls for building on existing research and implementing cross-sector approaches to Food Is Medicine. FIM programs aim to improve health outcomes by providing healthy food resources to treat, manage, and prevent specific chronic conditions.
A new study suggests that physiologically assessed hot flashes may be associated with greater systemic inflammation, a risk factor for heart disease. Midlife women experiencing frequent hot flashes may require focused cardiovascular disease prevention efforts.
The University of Texas at Arlington research team aims to develop a novel statistical model and machine learning algorithm to predict which patients will be cured from diseases such as cancer or cardiovascular disease. The goal is to identify patients who require additional treatments, thereby improving precision medicine.
A global comparative study assesses barriers to participation in cardiovascular rehabilitation programs for men and women, highlighting sex differences and regional variations. The study provides patients with mitigation strategies to address these barriers and improve CR utilization.
A new editorial addresses clinician burnout by proposing a unifying systems medicine model that incorporates biological, psychological, environmental, and consciousness factors. The authors suggest that Transcendental Meditation can enhance resilience and prevent burnout-related mind-body conditions.
A new study reveals that most healthcare facilities in low- and middle-income countries are unprepared to deliver services for treating cardiovascular disease risk factors, including diabetes and hypertension. However, investing in HIV care may provide a solution by improving readiness.
A significant burden of cardiovascular disease and cardiometabolic risk factors has been identified among 220,000 American Indian and Alaska Native patients with Medicare insurance. The study emphasizes the critical need for future efforts to prioritize cardiovascular health in this population.
A study published in Radiology: Cardiothoracic Imaging found that low- and middle-income countries reported persistent declines in cardiothoracic imaging procedure volumes after the COVID-19 pandemic. In contrast, high-income countries, including the US, recovered to pre-pandemic levels by 2021.
Researchers at the University of Alabama at Birmingham found that BNP levels are high in end-stage heart failure patients with cardiogenic shock, but no longer a reliable predictor of clinical outcomes after ventricular assist device (VAD) implantation. This study suggests reevaluating routine use of BNP testing for these patients.
Researchers at U of A are developing an AI-powered system to analyze cardiac images, enabling clinicians to diagnose heart disease more accurately. The project aims to reduce healthcare costs and improve patient outcomes, with potential global implications.
Researchers from Mass General Brigham find that traumatic brain injury increases risk of cardiovascular and cognitive dysfunction. Non-neurological conditions associated with TBI, such as hypertension and changes in the brain-gut connection, contribute to elevated cardiovascular risk.
A large study published in Journal of Investigative Dermatology found that patients with severe psoriasis have a high prevalence of coronary microvascular dysfunction, which is associated with increased cardiovascular risk. Psoriasis severity and duration, as well as the presence of psoriatic arthritis, are independently linked to redu...
A new electroenzymatic assembly transduction strategy-based biosensor has been developed for simultaneous detection of glucose, lactate, and cholesterol in clinical samples. The sensor exhibits high sensitivity and efficiency, with a detection time of under 30 seconds, and good agreement with laboratory results.
Climate change exacerbates cardiovascular disease through poor air quality and extreme temperatures, according to a special issue of the Canadian Journal of Cardiology. Experts review environmental influences, exposures, and practical tips for healthcare providers to mitigate these effects.
A study published in the Journal of the American Heart Association found that heavy alcohol consumption is associated with higher levels of ectopic fat, which can increase the risk of cardiovascular disease. The research team used CT scans to measure and analyze data on body fat distribution, revealing a J-shaped pattern between alcoho...
Researchers have developed an automated breath-by-breath measure to assess the severity of obstructive sleep apnea, predicting cardiovascular disease and mortality. The ventilatory burden tool provides a validated alternative to AHI, offering stable results and risk predictions.
A study of nearly 500,000 participants found that smoking shortens telomere length in white blood cells, a indicator of aging and cell regeneration. The more cigarettes smoked, the stronger the shortening effect, suggesting a link between smoking and accelerated aging.
A global study estimates that lead exposure causes 5.5 million cardiovascular deaths and loses 765 million IQ points in children under five years old annually. The economic cost of lead exposure is estimated to be $6 trillion, with the majority attributed to cardiovascular disease deaths.
Research presented at the European Respiratory Society International Congress suggests that CPAP machines can prevent deaths from heart disease and reduce cardiovascular problems in people with obstructive sleep apnea (OSA). A pilot study also found that CPAP may be more effective than a weight-loss drug in tackling clogged arteries.
Researchers at the University of Cincinnati have developed a new at-home test that uses saliva to detect early signs of gingivitis, the earliest form of gum disease. The device can identify periodontal disease caused by bacteria in saliva, providing an opportunity for consumers to protect their oral health.
Researchers found that people with high blood pressure while lying flat on their backs had a higher risk of heart attack, stroke, and premature death. The study suggests that measuring blood pressure in different body positions may help identify cardiovascular disease risk.
Jessica Faulkner, a physiologist at the Medical College of Georgia, has been awarded the Harry Goldblatt Award from the American Heart Association's Hypertension Council. Her research focuses on the role of leptin in preeclampsia and obesity-associated cardiovascular disease in women.
A recent study found a three-fold increase in obesity-related heart disease deaths in the US between 1999 and 2020. The study highlights racial disparities, particularly among Black women, who faced the highest rates of obesity-related cardiovascular mortality.
A comprehensive review of over 70 years of menopause science emphasizes the need for more research into symptom timeline and treatment effectiveness. The authors advocate for holistic, individualized approaches addressing physical and mental health impacts of menopause.
A recent study from Mayo Clinic found that exercise test abnormalities, such as low functional aerobic capacity, predicted non-cardiovascular causes of death like cancer, alongside cardiovascular-related deaths. The study's findings suggest that clinicians should focus on data beyond ECG results to identify patients at risk.
This review summarizes six common RNA modifications, including m6A, m5C, m1A, m7G, Ψ, and A-to-I editing, which play crucial roles in various human diseases. The authors discuss the mechanisms of these modifications and their targeting by small molecule inhibitors.
A study found that high intake of certain emulsifiers (E460-E468, E471, E472) is associated with increased risk of cardiovascular disease. The researchers suggest that these findings have important public health implications and may contribute to re-evaluation of food additive regulations.
A 4-month randomized controlled trial found that daily intake of resistant starch can lower liver triglycerides and liver enzymes associated with liver injury and inflammation. The treatment group had a different microbiota composition and functionality compared to the control group, leading to improved liver conditions.
A meta-analysis found that direct oral anticoagulants (DOACs) reduced dementia risk in Asian atrial fibrillation (AFib) patients compared to traditional blood thinners like warfarin. The benefit may reverse with increased age, necessitating further study.
A nationally representative study found that at least one out of five prescriptions for commonly prescribed generic medications were cheaper through Amazon Prime or GoodRx Gold discount cards compared to actual out-of-pocket payments made by patients. The findings highlight the disproportionately higher frequency of out-of-pocket payme...
A new study by Yale researchers found that despite reductions in fine particulate air pollution, racial and ethnic minorities still experience disproportionately high rates of cardiovascular disease-related deaths. The study found that Black people face the highest burden, with a mortality rate 4.59 times higher than white people in 2001.
Autophagy helps protect cardiomyocytes from damage caused by anthracycline drugs like Doxorubicin. The study found that a protein regulator called ER-phagy alleviates Dox-induced cardiomyopathy, promoting cell survival.
Researchers found that Dectin-1 stimulation induced a unique immune signature in HIV-positive older adults, characterized by increased levels of IL-12, TNF-α, and IFN-α. This signature may contribute to the pro-inflammatory environment associated with HIV and aging.
Researchers at State University of Campinas found that coconut oil supplementation led to significant alterations in food intake, weight gain, and anxious behavior in mice. The study suggests that long-term consumption of coconut oil can contribute to the development of obesity and associated comorbidities.
A new CNIC study confirms that controlling traditional cardiovascular risk factors can prevent Alzheimer's disease and dementia. Maintaining a low cardiovascular risk is linked to preserved cerebral glucose metabolism, indicating better brain health.
A recent clinical trial led by Professor Holger Thiele found that ECLS does not reduce 30-day mortality after cardiogenic shock, but is associated with more complications. The study involved 420 patients and compared ECLS therapy with standard intensive care unit treatment.
A new study found that people who received free produce prescriptions experienced increased fruit and vegetable consumption, leading to improved body mass index, blood sugar, and blood pressure levels. This research suggests that produce prescription programs may be an effective way to address food insecurity and promote health.
A global analysis of 2.3 million people reveals women are diagnosed and treated late for cardiac issues, with alarming rise in heart attacks among younger women. Non-traditional symptoms like vomiting, jaw pain, and abdominal pain are more common in women.
A study by the British Heart Foundation found that in England and Scotland, the average distance to a 24/7 accessible defibrillator is over 1.8km in deprived areas, highlighting alarming health inequalities. Researchers are urging urgent action to improve access to these lifesaving devices.
Muvalaplin, an oral small molecule inhibitor, significantly lowered lipoprotein(a) (Lp[a]) levels in a first-in-human phase 1 study. The treatment showed promise in reducing Lp[a] levels by up to 65% without tolerability concerns.
The Texas Heart Institute has received a five-year, $2 million grant from the National Institutes of Health to advance organ bioengineering. The project aims to develop transplantable bioartificial hearts to combat end-stage heart failure.
Atrial fibrillation patients in the UK are now 50% less likely to die from heart attacks and strokes than at the start of the millennium. The study revealed significant health inequalities, with socioeconomically deprived patients facing a higher risk of mortality.
Researchers have been awarded $600K each to lead projects improving healthcare access for underserved populations, including Black women and rural/minority communities. These projects will use innovative strategies such as at-home blood pressure monitoring and telemedicine-assisted testing to address health disparities.
Research led by Vesna D. Garovic reveals that pre-eclampsia causes accelerated aging in women, leading to increased risks of cardiovascular and kidney disease. Women with a history of pre-eclampsia are more likely to develop chronic conditions at a younger age.
Researchers found that severe COVID-19 survivors exhibit elevated muscle sympathetic nerve activity in response to mental stress, which accelerates heartbeat and increases blood pressure. This exaggerated reaction, combined with impaired vasodilation, poses a significant risk for cardiovascular complications.
Researchers found that telomere shortening, a biomarker of cellular aging, accelerated in untreated obstructive sleep apnea patients. However, continuous positive airway pressure (CPAP) attenuated this damage. The study suggests that CPAP can reduce inflammation and oxidative stress, leading to slower aging.
The study found that racial and ethnic disparities in cardiometabolic diseases persisted despite social risk factors adjustments. Individuals with a more favorable social risk factor profile had lower rates of lifestyle risk factors and cardiometabolic diseases.
The Texas Heart Institute has been awarded $1.14 million by the NIH to develop a novel, first-in-class drug for treating atherosclerotic cardiovascular disease. The goal of this research is to target lingering inflammation in patients with cardiovascular disease.
A new study found that catheter ablation significantly lowers the incidence of cardiovascular events and death in very old patients with nonvalvular atrial fibrillation. The researchers compared 208 patients who underwent AF ablation with those who received medical therapy only, finding a lower risk of both cardiovascular events and de...
A new study found that daily aspirin use could reduce cardiovascular deaths globally, yet fewer than half of people worldwide who have had a heart attack or stroke take the medication. The study showed significant variations in aspirin use among countries, with higher rates in high-income countries.
A new study found that a simple blood test can predict the risk of progressive heart and kidney disease in people with Type 2 diabetes. The test measures levels of four biomarkers, which fell after treatment with canagliflozin, a type 2 diabetes medicine.
Researchers identified a link between high white blood cells in saliva and compromised flow-mediated dilation, an early indicator of poor arterial health. The study suggests that low levels of oral inflammatory load may have an impact on cardiovascular health.
Chronic disease medications impair the body's ability to regulate core temperature, increasing the risk of heat-related illness in elderly patients. Exercise and improved fitness levels can help mitigate these effects, but bodily impairments from chemotherapy and medications may limit exercise capacity.
A new study finds that people who adhere to a Mediterranean lifestyle have a lower risk of all-cause and cancer mortality. The study, led by La Universidad Autónoma de Madrid and Harvard T.H. Chan School of Public Health, analyzed data from 110,799 participants and found an inverse association between adherence to the Mediterranean lif...
A recent study at UC Irvine found that semaglutide medication can lead to significant weight loss and reduce cardiovascular risk in 93 million U.S. adults. The medication may prevent up to 1.5 million heart attacks and strokes over 10 years, resulting in 43 million fewer obese people.
Researchers investigate how exposure to endocrine-disrupting chemicals in plastics may increase atherosclerosis and CVD risk, particularly in children. The study aims to establish a novel therapeutic target for chemical-induced CVD and explore gene-EDC interactions.
A large US study found that social determinants of health are a major factor contributing to higher cardiovascular disease mortality rates in Black individuals compared to Whites. The study analyzed data from over 50,000 adults and found significant associations between social factors such as unemployment and food insecurity with CVD m...
A new study from Tulane University found that Black adults are 54% more likely to die of cardiovascular disease than White Americans, largely due to social factors. The study's lead author suggests that addressing unemployment, low income, and lack of a partner can help reduce this disparity.
A new scientific statement from the American Heart Association highlights the importance of shared decision-making in cardiovascular care. Key findings include improved patient understanding, acceptance, and satisfaction when healthcare teams involve patients in decision-making processes.