A new American Heart Association scientific statement highlights the disproportionate burden of cardiovascular disease on AI/AN women. The study reveals that more than 60% of these women have suboptimal heart health when pregnant, increasing their risk of heart disease later in life.
Researchers developed an AI system, Geneformer, to predict how disruptions in human gene connections cause disease. The model, trained on data from thousands of genes, can identify potential drug targets for diseases like heart disease and cancer.
Research identifies Indian Hedgehog protein as a key driver of chronic kidney disease and heart damage, offering new hope for treatments. The findings suggest that blocking the protein's actions could improve kidney function and reduce cardiovascular risk.
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Two Kessler Foundation scientists will conduct studies on upper extremity exercise after stroke and restoration of cardiovascular function in spinal cord injury populations. Dr. Shenoy Handiru's study combines transcranial electrical stimulation and wearable sensor-based exergaming to improve hand dexterity, while Dr. Einat Engel-Haber...
A study from the University of Bergen reveals that women with a first normal weight offspring and a small second offspring have an increased risk of cardiovascular mortality. The research, published in the American Journal of Epidemiology, also found reduced risk if the second offspring was large.
Two researchers will receive $1 million each for their five-year studies on new medication-based approaches to repair damaged aortas, as well as the effects of exercise on healing heart muscle and brain tissue after a heart attack or stroke. The American Heart Association's Merit Award supports innovative research with high impact.
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Researchers identified five subtypes of heart failure using machine learning, including early onset and atrial fibrillation related. These subtypes have different mortality risks, with some patients at higher risk of dying within a year after diagnosis.
Researchers investigate whether pregnant mothers' exposure to toxic metals affects kidney development in their babies, which may set the stage for chronic kidney disease. The team aims to identify key combinations of metal mixtures that could have detrimental effects on developing kidneys.
A new study published in the European Heart Journal found that plant-based diets can play a significant role in reducing blocked arteries and lowering the risk of heart and blood vessel diseases. The analysis of 30 randomised trials with over 2,300 participants showed a 14% reduction in artery-clogging lipoproteins.
Researchers found that genetic predisposition to lipids, Alzheimer's, and heart disease in the MLXIPL gene locus is shaped by exogenous exposures. Minor alleles of certain variants associated with high triglyceride levels and lower HDL-C levels, which may provide protective effects against Alzheimer's risk.
Increasing physical activity, particularly daily 20-minute walks, can improve cardiovascular health and reduce disparities in heart health. Despite this, only one in four American adults meet the recommended physical activity levels, with certain groups facing additional barriers to accessibility.
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Women with short or long menstrual cycles are at increased risk of cardiovascular disease events such as heart attack or AFib. The study analyzed data from over 58,000 women and found that irregular menstrual cycle length was associated with higher risks of CVD, independent of other factors.
A literature review found that dietary nitrate from vegetables may prevent cardiovascular disease, while nitrate from meat and water may pose a cancer risk. Experts emphasize the need for clarification in current guidelines and more research to distinguish fact from fiction.
Dr. George Dangas has been appointed as the new President of SCAI, a non-profit professional association promoting excellence in interventional cardiovascular medicine. He is an authoritative voice on nonsurgical cardiovascular and valve interventions, and will fulfill various responsibilities including acting as spokesperson for SCAI.
Researchers have developed a pharmacological treatment that improves cardiac function in patients with stiff-heart syndrome, a condition caused by amyloid protein deposition. The new drug reduces amyloid protein deposits and shows promise in reversing established disease symptoms.
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Researchers analyzed cortisol and cortisone levels in over 6,300 individuals to find a strong link between long-term hair cortisone levels and future cardiovascular disease. People with higher cortisone levels were twice as likely to experience a cardiovascular event, especially those aged 57 or younger.
A study found that semaglutide use for one year decreases the 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with overweight or obesity. The treatment also leads to significant improvements in metabolic parameters, such as blood pressure, cholesterol, and fasting glucose levels.
A new study found an initial decline in diabetes mellitus plus cardiovascular disease-related mortality, but it reversed from 2014 to 2019. The researchers emphasized the need for primary prevention of diabetes and early diagnosis to prevent cardiovascular complications and mortality.
Researchers developed a new tool to predict heart disease risk in those over 40 based on their total exposure to heart disease risk factors. The study found that black patients have a 46% greater risk of developing heart disease compared to white patients.
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A new study suggests that catching up on sleep over the weekend can help reduce the risk of hyperuricemia in postmenopausal women. This is particularly relevant for those who struggle to get sufficient sleep during the week, as excessive or inadequate sleep has been linked to various health problems.
A new study found that lesbian and bisexual women are less likely to have ideal cardiovascular health scores compared to heterosexual women. In contrast, gay and bisexual men were more likely to have ideal cardiovascular health scores. The study highlights the need for prevention strategies among sexual minority adults in France.
A recent French study reveals lesbian and bisexual women have worse cardiovascular health scores than heterosexual women, while gay and bisexual men tend to have better scores. Rural-residing sexual minority men also experience poorer cardiovascular health compared to heterosexual men.
A new Northwestern Medicine study found young adult cancer survivors (18-39 years old) are 2.6 times more likely to develop heart failure when treated with anthracyclines. The incidence is highest among leukemia and other specific cancer types.
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A UK study of over 420,000 adults reveals that those with existing cardiovascular disease and overweight or obesity are five times more likely to suffer a stroke and four times more likely to have a heart attack than those with extreme obesity. The study highlights the substantial impact of living with both conditions on individuals, p...
A new study found that managing cardiovascular disease (CVD) risk factors can help preserve physical function in older adults. The research, led by Dr. Shivani Sahni, showed that vascular measures are associated with grip strength and change in gait speed.
The statement highlights enormous inequities in stroke care, leading to significant gaps in functional outcomes for historically disenfranchised groups. Upstream interventions, such as policy changes and place-based initiatives, are crucial to address these disparities.
Mortality rates from diabetes and cardiovascular disease increased significantly from 2014 to 2019, with patients with diabetes mellitus disproportionately affected. Researchers emphasize the need for better population-level control of diabetes to positively impact life expectancy.
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TVT 2023 will feature 15 Late-Breaking Clinical Science studies highlighting advances in transcatheter aortic valve replacement and mitral, tricuspid, and left atrial appendage occlusion therapies. The meeting aims to guide the selection of patients who will benefit from these procedures and define optimal treatment strategies.
A study by UMC Utrecht shows that corona patients can measure their blood oxygen levels at home using a pulse oximeter, feeling safe and experiencing more control. This method does not increase GP visits or hospitalization but contributes to relieving caregivers and keeping healthcare affordable.
A new study found that being overweight or obese during early and middle adulthood increases the risk of gastrointestinal cancers in later life. The research also suggests that frequent aspirin use does not modify this increased risk.
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A retrospective cohort study of U.S. veterans found that adding a GLP1 receptor agonist to diabetes treatment reduced the risk of major adverse cardiovascular events and heart failure hospitalization by about 20% compared to DPP4 inhibitors. The study's findings will aid clinicians in choosing a diabetes drug regimen for older patients.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
A University of Gothenburg study shows that increased physical activity, with four hours of weekly exercise, doubles the chances of recovering well by six months after a stroke. Men and people with normal cognition tend to maintain an active lifestyle more often, leading to better recovery outcomes.
Recent cluster analyses identify novel risk stratification concepts to better implement precision medicine in clinical practice. Metabolically unhealthy individuals, regardless of weight, face a higher CVD risk compared to obese, metabolically healthy peers.
Researchers at West Virginia University found that bariatric surgery significantly reduces the risk of major cardiovascular events and death in patients with NAFLD. The study included 9,374 adult patients with NAFLD and obesity, who underwent either Roux-en-Y gastric bypass or sleeve gastrectomy.
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Scientists discovered that inhibiting microRNA-141-3p can reduce chronic inflammation, muscle loss, and bone degradation in aged mice. By blocking this tiny RNA, researchers found improvements in the spleen's immune response, lower levels of pro-inflammatory proteins, and a more youthful profile in bones and muscles.
Researchers analyzed data from over 20,000 US adults, finding that those who lost at least 5% of their body weight showed higher diet quality and more moderate physical activity. However, the study also found that many individuals relied on unsustainable non-evidence-based approaches for weight loss, highlighting the need for a paradig...
A new study published in European Journal of Preventive Cardiology reveals that non-optimal temperatures have a significant impact on global cardiovascular disease burden, contributing to nearly 1.2 million CVD deaths and 22 million disability-adjusted life years (DALYs) annually.
A new study published by Edith Cowan University found that boxing programs can improve symptoms of Parkinson's Disease, including fatigue and sleep, in early-stage patients. The program combined elements of exercise, computerized cognitive training, and socialization into a single activity.
Researchers found that when FXR1 is absent, vascular smooth muscle cells proliferate more slowly, become senescent, and scar tissue development is reduced. This suggests that drugs targeting FXR1 may treat vascular proliferative diseases such as atherosclerosis, restenosis, hypertension, and abdominal aortic aneurysm.
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A new study reveals delayed diagnosis of HoFH leads to premature cardiovascular disease, highlighting the need for increased lipid screening and aggressive treatment. Despite available therapies, most patients require further lipid-lowering treatments.
A study found that young women are more likely to experience adverse outcomes and rehospitalization after a heart attack, with non-cardiac hospitalizations showing the most significant disparity. Researchers highlight the need for public awareness and sex-specific post-heart attack care.
The American Heart Association scientific statement rates how closely popular dietary patterns align with its guidance for heart-healthy eating. The statement evaluates 10 categories of diets, scoring them from 31 to 100 based on their alignment with the guidance, with some diets receiving high scores while others need improvement.
Researchers have developed a 'vein-on-a-chip' device that mimics the human vein, eliminating the need for animal models in some studies. The device, which includes structures called valves and endothelial cells, allows scientists to study mechanisms of blood clot formation in a realistic manner.
A new study published in the Journal of the American Heart Association found that U.S. adults who experienced workplace discrimination were more likely to develop high blood pressure. The research, which analyzed data from over 1,200 adults, suggests that work-related stress due to discrimination may be an emerging risk factor for card...
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A new study comparing outcomes between Ontario and New York State found patients in Ontario more likely to die within a month of procedure due to inadequate availability and long wait times. The study suggests that improved access to TAVR may lead to better post-procedural outcomes.
A recent study published in JAMA Pediatrics reveals that individuals born preterm or large for gestational age have a significantly increased risk of developing atrial fibrillation up to middle-age. In contrast, those born small for gestational age only show an increased risk up to the age of 18.
A study of over 7,000 patients found that Black and socioeconomically disadvantaged patients with vascular disease have more severe symptoms before bypass surgery and are at greater risk for amputation and other complications after the procedure. Advanced disease accounted for up to half the effect of race on odds for amputation after ...
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A new study found that quality of heart failure care is equitable for 11 of 14 evidence-based clinical care measures, with no disparities in care between Black and white patients. However, the study highlights areas for improvement, including gaps in care quality and social determinants of health.
Individuals who experienced depression during pregnancy were more likely to be diagnosed with cardiovascular disease within two years after giving birth. The study found a significant higher risk of developing six major cardiovascular conditions, including heart failure and ischemic heart disease.
Using mice, researchers successfully converted scar tissue back into functioning cardiac muscle using RNAs and exosomes, offering new hope for reversing heart attack damage. The study also sheds light on the aging process's impact on cellular reprogramming.
A new study found that high consumption of sugar-sweetened beverages was associated with an elevated risk of premature death and incidence of cardiovascular disease among people with type 2 diabetes. Drinking healthier beverages like coffee, tea, and plain water was linked to lower risk of dying prematurely.
A UK Biobank study found that cancer survivors may be at long-term increased risk of cardiovascular disease, regardless of traditional risk factors. Those with previous breast or blood cancers were found to have the greatest risk, with significant changes in heart size and function detected on MRI scans.
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Researchers found that people whose depression symptoms improved after psychological treatment had a lower risk of developing cardiovascular disease over three years. The association was strongest in younger adults and suggested that accessing psychological therapy could have long-term physical health benefits.
A Mayo Clinic study found that people with severe obesity and a genetic pathway variant are at increased risk of developing hypertension. The research identified 168 carriers of the MC4R variant, who had a higher risk of hypertension compared to noncarriers.
A team of UCF College of Medicine researchers created a digital topographical map of the cardiac sympathetic neural network, controlling heart rate and 'fight-or-flight' response. The map will guide treatments like neuromodulation therapy for hypertension, sleep apnea, and heart failure.
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Researchers found that removing ovaries during a benign hysterectomy increases the risk of hospitalization for cardiovascular disease in premenopausal women, but not necessarily for cancer. The study supports current recommendations to conserve ovaries in premenopausal patients at low risk for ovarian cancer.
Spanish footballer Iker Casillas was awarded an EHRA Gold Medal for his efforts in raising awareness about heart health and reducing preventable deaths. The award aims to highlight the importance of recognizing warning signs of a heart attack and seeking immediate medical attention.
Researchers used a novel machine-learning technique called causal forest, which found that treating individuals with high estimated benefits provided better population health outcomes than the traditional high-risk approach. This approach targets those with high blood pressure and could lead to more effective treatment strategies.
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A new study found that sedentary time increases cardiac mass by 3.8g/m2.7, while moderate-to-vigorous physical activity results in a smaller increase of 1.2g/m2.7. Light physical activity shows no effect on cardiac mass but improves cardiac function.