Articles tagged with Cardiovascular Disease
A retrospective cohort study of U.S. veterans found that adding a GLP1 receptor agonist to diabetes treatment reduced the risk of major adverse cardiovascular events and heart failure hospitalization by about 20% compared to DPP4 inhibitors. The study's findings will aid clinicians in choosing a diabetes drug regimen for older patients.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
Researchers at West Virginia University found that bariatric surgery significantly reduces the risk of major cardiovascular events and death in patients with NAFLD. The study included 9,374 adult patients with NAFLD and obesity, who underwent either Roux-en-Y gastric bypass or sleeve gastrectomy.
Researchers found that when FXR1 is absent, vascular smooth muscle cells proliferate more slowly, become senescent, and scar tissue development is reduced. This suggests that drugs targeting FXR1 may treat vascular proliferative diseases such as atherosclerosis, restenosis, hypertension, and abdominal aortic aneurysm.
A new study reveals delayed diagnosis of HoFH leads to premature cardiovascular disease, highlighting the need for increased lipid screening and aggressive treatment. Despite available therapies, most patients require further lipid-lowering treatments.
Scientists discovered that inhibiting microRNA-141-3p can reduce chronic inflammation, muscle loss, and bone degradation in aged mice. By blocking this tiny RNA, researchers found improvements in the spleen's immune response, lower levels of pro-inflammatory proteins, and a more youthful profile in bones and muscles.
Researchers analyzed data from over 20,000 US adults, finding that those who lost at least 5% of their body weight showed higher diet quality and more moderate physical activity. However, the study also found that many individuals relied on unsustainable non-evidence-based approaches for weight loss, highlighting the need for a paradig...
A new study published in European Journal of Preventive Cardiology reveals that non-optimal temperatures have a significant impact on global cardiovascular disease burden, contributing to nearly 1.2 million CVD deaths and 22 million disability-adjusted life years (DALYs) annually.
A new study published by Edith Cowan University found that boxing programs can improve symptoms of Parkinson's Disease, including fatigue and sleep, in early-stage patients. The program combined elements of exercise, computerized cognitive training, and socialization into a single activity.
A study found that young women are more likely to experience adverse outcomes and rehospitalization after a heart attack, with non-cardiac hospitalizations showing the most significant disparity. Researchers highlight the need for public awareness and sex-specific post-heart attack care.
Researchers have developed a 'vein-on-a-chip' device that mimics the human vein, eliminating the need for animal models in some studies. The device, which includes structures called valves and endothelial cells, allows scientists to study mechanisms of blood clot formation in a realistic manner.
The American Heart Association scientific statement rates how closely popular dietary patterns align with its guidance for heart-healthy eating. The statement evaluates 10 categories of diets, scoring them from 31 to 100 based on their alignment with the guidance, with some diets receiving high scores while others need improvement.
A new study published in the Journal of the American Heart Association found that U.S. adults who experienced workplace discrimination were more likely to develop high blood pressure. The research, which analyzed data from over 1,200 adults, suggests that work-related stress due to discrimination may be an emerging risk factor for card...
A new study comparing outcomes between Ontario and New York State found patients in Ontario more likely to die within a month of procedure due to inadequate availability and long wait times. The study suggests that improved access to TAVR may lead to better post-procedural outcomes.
A recent study published in JAMA Pediatrics reveals that individuals born preterm or large for gestational age have a significantly increased risk of developing atrial fibrillation up to middle-age. In contrast, those born small for gestational age only show an increased risk up to the age of 18.
A new study found that quality of heart failure care is equitable for 11 of 14 evidence-based clinical care measures, with no disparities in care between Black and white patients. However, the study highlights areas for improvement, including gaps in care quality and social determinants of health.
Individuals who experienced depression during pregnancy were more likely to be diagnosed with cardiovascular disease within two years after giving birth. The study found a significant higher risk of developing six major cardiovascular conditions, including heart failure and ischemic heart disease.
Using mice, researchers successfully converted scar tissue back into functioning cardiac muscle using RNAs and exosomes, offering new hope for reversing heart attack damage. The study also sheds light on the aging process's impact on cellular reprogramming.
A new study found that high consumption of sugar-sweetened beverages was associated with an elevated risk of premature death and incidence of cardiovascular disease among people with type 2 diabetes. Drinking healthier beverages like coffee, tea, and plain water was linked to lower risk of dying prematurely.
A study of over 7,000 patients found that Black and socioeconomically disadvantaged patients with vascular disease have more severe symptoms before bypass surgery and are at greater risk for amputation and other complications after the procedure. Advanced disease accounted for up to half the effect of race on odds for amputation after ...
Researchers found that people whose depression symptoms improved after psychological treatment had a lower risk of developing cardiovascular disease over three years. The association was strongest in younger adults and suggested that accessing psychological therapy could have long-term physical health benefits.
A Mayo Clinic study found that people with severe obesity and a genetic pathway variant are at increased risk of developing hypertension. The research identified 168 carriers of the MC4R variant, who had a higher risk of hypertension compared to noncarriers.
A UK Biobank study found that cancer survivors may be at long-term increased risk of cardiovascular disease, regardless of traditional risk factors. Those with previous breast or blood cancers were found to have the greatest risk, with significant changes in heart size and function detected on MRI scans.
Spanish footballer Iker Casillas was awarded an EHRA Gold Medal for his efforts in raising awareness about heart health and reducing preventable deaths. The award aims to highlight the importance of recognizing warning signs of a heart attack and seeking immediate medical attention.
A team of UCF College of Medicine researchers created a digital topographical map of the cardiac sympathetic neural network, controlling heart rate and 'fight-or-flight' response. The map will guide treatments like neuromodulation therapy for hypertension, sleep apnea, and heart failure.
Researchers found that removing ovaries during a benign hysterectomy increases the risk of hospitalization for cardiovascular disease in premenopausal women, but not necessarily for cancer. The study supports current recommendations to conserve ovaries in premenopausal patients at low risk for ovarian cancer.
Researchers used a novel machine-learning technique called causal forest, which found that treating individuals with high estimated benefits provided better population health outcomes than the traditional high-risk approach. This approach targets those with high blood pressure and could lead to more effective treatment strategies.
A new study found that sedentary time increases cardiac mass by 3.8g/m2.7, while moderate-to-vigorous physical activity results in a smaller increase of 1.2g/m2.7. Light physical activity shows no effect on cardiac mass but improves cardiac function.
A new study from Uppsala University found that patients can experience twice as much improvement in blood pressure by changing medication as they would by doubling their current dose. The study, involving 280 patients and testing four different blood pressure-lowering drugs, challenges the conventional strategy of recommending equally ...
A daily statin medication reduced the risk of major adverse cardiovascular events by 35% among people living with HIV. The NIH study, REPRIEVE, enrolled over 7,700 volunteers and found that pitavastatin calcium lowered cardiovascular risk without increasing adverse drug events.
The new American Heart Association scientific statement emphasizes the importance of including non-biological factors and social determinants in CVD risk assessment for women. These factors include economic stability, neighborhood safety, education level, and access to quality healthcare, which disproportionately affect women from dive...
Researchers from Karolinska Institutet found that people with obesity due to genetic predisposition have a lower risk of cardiovascular disease. The study analyzed data from over 15,000 twins and medical registries, suggesting that genetics may play a role in mitigating the risk of cardiovascular disease.
Researchers found decreased lung injury, coughing up blood, and mortality rates after balloon pulmonary angioplasty between 2013 and 2022. The minimally invasive procedure is now considered a safer option for inoperable CTEPH patients.
A new proteomic risk model developed by Penn Medicine researchers is more accurate than existing clinical models for predicting cardiovascular risk among chronic kidney disease patients. The model uses nearly 5,000 proteins and identified specific proteins that can help identify individuals at high risk of future cardiovascular events.
Researchers at TUM have developed a method to create mini-hearts in Petri dishes using stem cells. The resulting organoids mimic the earliest stages of human heart development and can be used to investigate congenital heart defects, potentially leading to new treatment methods.
Researchers found that statin users can engage in moderate-intensity exercise without exacerbating muscle injury or symptoms. The study's findings are reassuring for people experiencing muscle pain or fatigue from statins and provide important guidance for maintaining physical activity and heart health.
A new study published in The European Heart Journal – Digital Health found that smart watch data can predict a higher risk of developing heart failure and irregular heart rhythms. Researchers used machine learning to analyze ECG recordings from wearable devices and identified extra beats as indicators of increased cardiovascular risk.
Researchers successfully add purified curcumin to probiotic yogurt, preserving its dissolved form and enhancing its health properties. The study shows that the curcumin inhibits yeast, fungi, and bacteria growth while maintaining the recommended levels of beneficial lactic acid bacteria.
Studies found that certain T cells in human blood can produce acetylcholine, regulating blood pressure and inflammation. Higher levels of these immune cells were associated with reduced risk of death in seriously ill patients.
Researchers compared seven dietary programmes, finding Mediterranean programmes lower risk of mortality, non-fatal heart attacks, and stroke. Low fat programmes also showed benefits for mortality and non-fatal heart attacks, but with less pronounced effects.
Researchers at Sanford Burnham Prebys have identified a group of proteins called AJSZ that help solve a known problem in cellular reprogramming. By blocking the activity of these proteins, they were able to reduce scarring on the heart and induce a 50% improvement in overall heart function in mice that have undergone a heart attack.
A new AI tool analyzed food consumption data from over 600 residents in long-term care homes, revealing a need for improved dietary habits. The study suggests that a diet rich in whole grains, plant-based proteins, and plain fruits and vegetables can help reduce inflammation and improve clinical outcomes.
A team of researchers from Ohio University discovered that CIDEC protein improves vascular and metabolic dysfunction, reducing insulin resistance and lipid levels in high-fat diet-induced mice. The study contributes to understanding the role of the vascular endothelium in regulating systemic metabolism.
Research highlights that intensive behavioral weight loss programs significantly reduce cardiovascular disease and Type 2 diabetes risk factors, which persist for at least five years. Participants who lost weight through such programs had lower risk factors compared to those in less intensive or no weight loss programs.
Three pre-clinical studies published in Journal of Pharmaceutical Analysis explore the molecular mechanisms underlying cardiovascular and neurological diseases, providing new avenues for therapeutic strategies.
A cohort study of over 9,000 persons found that asymptomatic middle-aged individuals with subclinical coronary atherosclerosis are at an 8-fold increased risk for myocardial infarction. The study highlights the importance of identifying and addressing obstructive coronary artery disease in patients without known cardiovascular disease.
A study published in Lasers in Surgery and Medicine suggests that light therapy, known as photobiomodulation (PBM), can improve heart function and reduce the thickness of the cardiac wall in middle-aged mice. The research also found improved neuromuscular coordination and a significant survival rate among mice with severe heart disease.
A new American Heart Association scientific statement provides guidance on interpreting incidental genetic variants associated with cardiovascular disease risk. The statement aims to determine whether a variant truly carries a health risk and suggests next steps for individuals and healthcare professionals.
A study of global clinical practice guidelines found close alignment in recommending daily intake of fruits, vegetables, legumes, and whole grains for treating and preventing major chronic diseases. The findings aim to increase clinician confidence in providing optimal care.
A new study found that Hispanic, Black, and low-socioeconomic status smokers are less likely to use e-cigarettes as a quit-smoking tool and more likely to believe e-cigarettes pose greater harm than cigarettes. This perception may prevent e-cigarette uptake among these populations, exacerbating racial and health disparities in smoking.
The Lp(a) Discovery Project will develop clinical standards for optimal patient care through a new screening measure and quality improvement interventions. The three-year project aims to fill knowledge gaps around Lp(a) and encourage better treatments to reduce cardiovascular risk.
UConn researchers have developed simple measurements and equations that better predict fat distribution in individuals based on their sex and ethnicity. The tools account for differences in body composition between ethnic populations and women and men, providing a more accurate assessment of obesity-related health risks.
A 29-year study found that being fit reduces the risk of death from cardiovascular disease in men with high blood pressure. High fitness levels attenuate, but do not eliminate, the increased risk of cardiovascular mortality in individuals with elevated blood pressure.
The study found that statin use for primary prevention was low among all racial and ethnic groups, despite varying levels of 10-year ASCVD risk. Improving access to care may help increase equitable use of primary prevention statins in Black and Hispanic adults.
A clinical trial found that moderate salt restriction reduced blood pressure and depressive symptoms without adverse effects in patients with primary aldosteronism. The study suggests a feasible approach to improving care for these patients and may also benefit those with essential hypertension.
A new study finds that smokeless tobacco products increase the risk of developing peripheral artery disease by two-fold compared to non-users. The study analyzed data from 14,344 participants and found a significant association between smokeless tobacco use and PAD, with a rate of 4.4 cases per 1,000 person years.
The VALOR-QI program will provide a blueprint for quality care improvement, focusing on high-risk patients and addressing health equity gaps. It will offer education, staff training, monitoring, and other steps to achieve better compliance with cholesterol management.
A new study published in the European Heart Journal shows that using waist-to-height ratio instead of BMI provides a clearer picture of patient outcomes in heart failure. The researchers found that greater adiposity is associated with worse outcomes, including high rates of hospitalization and reduced health-related quality of life.
A real-world analysis found that high-risk Americans who fail to reach guideline-recommended LDL-C levels experience a 44% higher rate of cardiovascular events. The study, presented at the AMCP Conference, used data from over 300 million Americans and compared those who met and maintained recommended targets with those who did not.
A study by Tokyo Medical and Dental University reveals that chronic kidney disease promotes vascular calcification by altering signaling molecules in blood vessel walls. The researchers identified four microRNAs that target a key pathway driving calcification, providing potential biomarkers and therapeutic targets for both diseases.