Articles tagged with Cardiovascular Disease
Recent studies in the New Journal of Pharmaceutical Analysis feature novel diagnostic tools, RNA sequencing-based workflows, and mechanical property evaluations to enhance cancer and cardiovascular disease treatment outcomes. These innovations aim to improve the therapeutic effect of drugs and promote personalized medicine.
A new study by CNIC researchers reveals that low-grade systemic inflammation triggered by subclinical atherosclerosis accelerates epigenetic aging in otherwise healthy young individuals. The study found a strong association between atherosclerosis progression and accelerated biological age, with potential reversibility through lifestyl...
The study analyzed data from 15 hospitals nationwide and found that nearly half of patients with symptomatic severe AS received transcatheter aortic valve replacement, while about 36% did not receive any treatment. The program aims to address healthcare disparities in AS care by identifying best practices for treating the disease.
Research presented at ENDO 2023 found women with PCOS died 47% earlier than those without the condition. They were also at higher risk for deaths due to cardiovascular disease, tumors, diabetes, and lung infections.
Peripheral artery disease (PAD) disproportionately affects Black adults, with higher rates of diagnosis and poor outcomes. Low-cost, routine testing can help reduce disparities and health care costs by identifying individuals at risk and providing preventive measures.
Researchers used a new transgenic mouse model to study the impact of oxidative stress on neurons and blood vessels, revealing that high levels of stress can cause sensory neuron degeneration and cardiac hypertrophy. This combination is associated with Friedreich's ataxia, a progressive neurodegenerative disease.
A new study found that elevated Lipoprotein(a) levels are a significant predictor of recurrent coronary heart disease (CHD) in people over 60. The study suggests current cholesterol-lowering medications may not be effective in reducing the risk of recurrent CHD, highlighting the need for novel therapeutics to target elevated Lp(a).
Researchers at Temple University Health System discovered a promising alternative to control hypertension and associated cardiovascular problems. The infused juice concentrate from the Japanese plum was found to attenuate growth-promoting signals induced by angiotensin II, reducing hypertrophy of the aorta and inflammation.
A new study from Keck Medicine of USC reveals significant racial disparities in the diagnosis and treatment of peripheral artery disease (PAD) among Black and white patients. Black patients are nearly 50% less likely to receive vascular interventions, leading to a higher risk of stroke, heart attack, or amputation.
Researchers found that light to moderate drinking reduces stress signaling in the brain, accounting for lower cardiovascular events. The study's findings suggest a potential new approach to reducing heart disease risk without the negative health effects of alcohol.
A new study published in Journal of Leukocyte Biology found that age and sex differences contribute to increased inflammation in older female mice. The research team discovered that immune cells entering areas where they shouldn
Chronic exposure to low levels of contaminant metals through household items, air, water, soil, and food increases the risk of cardiovascular disease. Monitoring environmental metal levels and testing for exposure are key steps to implement public health initiatives.
Research highlights chronic exposure to contaminant metals as a modifiable risk factor for cardiovascular disease. Monitoring environmental metal levels and testing individuals can help implement public health initiatives.
A new study published in JMIR Cardio reveals the potential of AI-QCA in analyzing coronary angiography, providing accurate measurements of coronary stenotic lesions similar to IVUS. This technology has the potential to improve patient outcomes and support clinical decision-making.
The American Heart Association invites researchers to compete in a data challenge to better understand how lipoprotein(a) levels impact cardiovascular disease and stroke risk. The winning project can receive a $40,000 cash prize.
A new metric, space syntax walkability index, is proposed to address limitations in linking cardio-metabolic risk factors to the built environment. The study found that walkability in urban areas is linked to cardio-metabolic risk factors, including blood pressure and obesity.
A new study shows that saracatinib reduces inflammation in patients with atherosclerotic cardiovascular disease by more than 90% and boosts genes that help clean up plaque deposits. The experimental cancer drug may offer an effective therapy for cases where standard treatment fails to help.
Researchers found increased levels of TMAO in abdominal aortic aneurysm (AAA) patients, which led to disease progression. Inhibiting TMAO production reduced aneurysm severity, suggesting a potential therapeutic target.
A study of US adults found that fewer than 1 in 4 use wearable devices to prevent or manage cardiovascular disease, with inconsistent daily use among those who do. This disparity may worsen health inequalities unless strategies are implemented to promote equitable adoption of these tools.
A randomized clinical trial found that peer health coaching improved mental health-related quality of life in veterans with cardiovascular disease risks. The study suggests a peer-support model integrated into primary care can lead to well-being improvements beyond blood pressure control.
Researchers found that women with higher-quality cardiovascular fat during midlife had stronger long-term memory and lower inflammation, while those with lower-quality fat had worsening working memory. The study suggests that taking care of heart health during menopause may protect brain health and reduce dementia risk.
A new study published in Hypertension found that oral estrogen hormone therapy may increase the risk of high blood pressure in women, while transdermal and vaginal formulations appeared to have a lower impact. The research involved over 112,000 women aged 45 years and older who took estrogen-only hormone therapy.
A new study by the University of Utah Health reveals that people with higher cardiovascular disease risk are more likely to develop musculoskeletal disorders. The study suggests prioritizing cardiovascular health can help prevent these conditions and improve quality of life.
Researchers at Lund University have mapped the location where atherosclerotic plaques rupture, identifying an enzyme marker that could predict patients at risk of myocardial infarction or stroke. The study's findings may lead to preventive treatments and new therapies.
Researchers at the University of Arizona studied the impact of grief on heart function and found a significant association between grief severity and elevated systolic blood pressure response. Grief can cause a marked rise in blood pressure, increasing the risk of cardiac events.
A new American Heart Association scientific statement highlights the disproportionate burden of cardiovascular disease on AI/AN women. The study reveals that more than 60% of these women have suboptimal heart health when pregnant, increasing their risk of heart disease later in life.
Researchers developed an AI system, Geneformer, to predict how disruptions in human gene connections cause disease. The model, trained on data from thousands of genes, can identify potential drug targets for diseases like heart disease and cancer.
Research identifies Indian Hedgehog protein as a key driver of chronic kidney disease and heart damage, offering new hope for treatments. The findings suggest that blocking the protein's actions could improve kidney function and reduce cardiovascular risk.
A new study published in the Journal of the American Heart Association found that elevated levels of two protein biomarkers associated with heart damage were linked to undetected or symptomless cardiovascular disease in adults with Type 2 diabetes. The study analyzed health information and blood samples from over 10,300 adults and foun...
Researchers at UBC Okanagan found that a low-carb breakfast can significantly reduce blood sugar swings and improve glucose control. Participants who followed a low-carb breakfast plan showed lower glycemic variability and some were able to reduce their glucose-lowering medication.
Two Kessler Foundation scientists will conduct studies on upper extremity exercise after stroke and restoration of cardiovascular function in spinal cord injury populations. Dr. Shenoy Handiru's study combines transcranial electrical stimulation and wearable sensor-based exergaming to improve hand dexterity, while Dr. Einat Engel-Haber...
A study from the University of Bergen reveals that women with a first normal weight offspring and a small second offspring have an increased risk of cardiovascular mortality. The research, published in the American Journal of Epidemiology, also found reduced risk if the second offspring was large.
Researchers identified five subtypes of heart failure using machine learning, including early onset and atrial fibrillation related. These subtypes have different mortality risks, with some patients at higher risk of dying within a year after diagnosis.
Two researchers will receive $1 million each for their five-year studies on new medication-based approaches to repair damaged aortas, as well as the effects of exercise on healing heart muscle and brain tissue after a heart attack or stroke. The American Heart Association's Merit Award supports innovative research with high impact.
Researchers investigate whether pregnant mothers' exposure to toxic metals affects kidney development in their babies, which may set the stage for chronic kidney disease. The team aims to identify key combinations of metal mixtures that could have detrimental effects on developing kidneys.
Increasing physical activity, particularly daily 20-minute walks, can improve cardiovascular health and reduce disparities in heart health. Despite this, only one in four American adults meet the recommended physical activity levels, with certain groups facing additional barriers to accessibility.
Women with short or long menstrual cycles are at increased risk of cardiovascular disease events such as heart attack or AFib. The study analyzed data from over 58,000 women and found that irregular menstrual cycle length was associated with higher risks of CVD, independent of other factors.
A new study published in the European Heart Journal found that plant-based diets can play a significant role in reducing blocked arteries and lowering the risk of heart and blood vessel diseases. The analysis of 30 randomised trials with over 2,300 participants showed a 14% reduction in artery-clogging lipoproteins.
Researchers found that genetic predisposition to lipids, Alzheimer's, and heart disease in the MLXIPL gene locus is shaped by exogenous exposures. Minor alleles of certain variants associated with high triglyceride levels and lower HDL-C levels, which may provide protective effects against Alzheimer's risk.
A literature review found that dietary nitrate from vegetables may prevent cardiovascular disease, while nitrate from meat and water may pose a cancer risk. Experts emphasize the need for clarification in current guidelines and more research to distinguish fact from fiction.
Researchers have developed a pharmacological treatment that improves cardiac function in patients with stiff-heart syndrome, a condition caused by amyloid protein deposition. The new drug reduces amyloid protein deposits and shows promise in reversing established disease symptoms.
Dr. George Dangas has been appointed as the new President of SCAI, a non-profit professional association promoting excellence in interventional cardiovascular medicine. He is an authoritative voice on nonsurgical cardiovascular and valve interventions, and will fulfill various responsibilities including acting as spokesperson for SCAI.
Researchers analyzed cortisol and cortisone levels in over 6,300 individuals to find a strong link between long-term hair cortisone levels and future cardiovascular disease. People with higher cortisone levels were twice as likely to experience a cardiovascular event, especially those aged 57 or younger.
A study found that semaglutide use for one year decreases the 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with overweight or obesity. The treatment also leads to significant improvements in metabolic parameters, such as blood pressure, cholesterol, and fasting glucose levels.
A new study suggests that catching up on sleep over the weekend can help reduce the risk of hyperuricemia in postmenopausal women. This is particularly relevant for those who struggle to get sufficient sleep during the week, as excessive or inadequate sleep has been linked to various health problems.
A new study found that lesbian and bisexual women are less likely to have ideal cardiovascular health scores compared to heterosexual women. In contrast, gay and bisexual men were more likely to have ideal cardiovascular health scores. The study highlights the need for prevention strategies among sexual minority adults in France.
A recent French study reveals lesbian and bisexual women have worse cardiovascular health scores than heterosexual women, while gay and bisexual men tend to have better scores. Rural-residing sexual minority men also experience poorer cardiovascular health compared to heterosexual men.
A new study found an initial decline in diabetes mellitus plus cardiovascular disease-related mortality, but it reversed from 2014 to 2019. The researchers emphasized the need for primary prevention of diabetes and early diagnosis to prevent cardiovascular complications and mortality.
Researchers developed a new tool to predict heart disease risk in those over 40 based on their total exposure to heart disease risk factors. The study found that black patients have a 46% greater risk of developing heart disease compared to white patients.
A UK study of over 420,000 adults reveals that those with existing cardiovascular disease and overweight or obesity are five times more likely to suffer a stroke and four times more likely to have a heart attack than those with extreme obesity. The study highlights the substantial impact of living with both conditions on individuals, p...
A new Northwestern Medicine study found young adult cancer survivors (18-39 years old) are 2.6 times more likely to develop heart failure when treated with anthracyclines. The incidence is highest among leukemia and other specific cancer types.
The statement highlights enormous inequities in stroke care, leading to significant gaps in functional outcomes for historically disenfranchised groups. Upstream interventions, such as policy changes and place-based initiatives, are crucial to address these disparities.
A new study found that managing cardiovascular disease (CVD) risk factors can help preserve physical function in older adults. The research, led by Dr. Shivani Sahni, showed that vascular measures are associated with grip strength and change in gait speed.
TVT 2023 will feature 15 Late-Breaking Clinical Science studies highlighting advances in transcatheter aortic valve replacement and mitral, tricuspid, and left atrial appendage occlusion therapies. The meeting aims to guide the selection of patients who will benefit from these procedures and define optimal treatment strategies.
Mortality rates from diabetes and cardiovascular disease increased significantly from 2014 to 2019, with patients with diabetes mellitus disproportionately affected. Researchers emphasize the need for better population-level control of diabetes to positively impact life expectancy.
A new study found that being overweight or obese during early and middle adulthood increases the risk of gastrointestinal cancers in later life. The research also suggests that frequent aspirin use does not modify this increased risk.
A study by UMC Utrecht shows that corona patients can measure their blood oxygen levels at home using a pulse oximeter, feeling safe and experiencing more control. This method does not increase GP visits or hospitalization but contributes to relieving caregivers and keeping healthcare affordable.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
A University of Gothenburg study shows that increased physical activity, with four hours of weekly exercise, doubles the chances of recovering well by six months after a stroke. Men and people with normal cognition tend to maintain an active lifestyle more often, leading to better recovery outcomes.
Recent cluster analyses identify novel risk stratification concepts to better implement precision medicine in clinical practice. Metabolically unhealthy individuals, regardless of weight, face a higher CVD risk compared to obese, metabolically healthy peers.