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Mortality and morbidity among individuals with hypertension receiving a diuretic, ace inhibitor, or calcium channel blocker

A secondary analysis of a randomized clinical trial found that cardiovascular disease mortality was similar among individuals with hypertension receiving diuretics, calcium channel blockers, or ACE inhibitors. However, ACE inhibitors were associated with an increased risk of stroke outcomes by 11% compared to diuretics.

SourceJAMA Network·JournalJAMA Network Open·DateDec 4, 2023

The risk of cardiovascular disease can be reduced by eating more oily fish

A new study finds that consuming more oily fish like salmon and mackerel can lower the risk of cardiovascular diseases in people with a family history. The research suggests that these fatty acids EPA/DHA play a crucial role in mitigating this risk, especially for those with close relatives who have suffered from cardiovascular disease.

SourceKarolinska Institutet·JournalCirculation·TypeObservational study·DateDec 4, 2023

CNIC and the i+12 Institute participate in the most ambitious EU project to reduce the burden of cardiovascular diseases and diabetes

The Joint Action on Cardiovascular Diseases and Diabetes (JACARDI) aims to reduce the burden of cardiovascular diseases and diabetes in EU member states through 143 pilot projects. The project will test and offer solutions throughout the patient journey, focusing on prevention, early detection, treatment, care, and self-management.

Most adults eligible for statins for prevention are not using them

According to a new study published in Annals of Internal Medicine, most adults who qualify for statin use for primary prevention are not receiving them. The study found that despite increased overall statin use over time, only 35% of eligible adults were taking statins between 2013 and 2018. The researchers suggest that innovative effo...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateDec 4, 2023

UAB researchers demonstrate how genetics play a role in the development of hypertension

A recent study published in Circulation: Genomic and Precision Medicine reveals that genetics significantly contribute to the sex differences in hypertension development. The research found that females with high genetic risk scores had a higher risk of hypertension compared to males, while low-risk females had a lower risk than males.

SourceUniversity of Alabama at Birmingham·JournalCirculation·TypeData/statistical analysis·DateDec 1, 2023

Early rhythm control, lifestyle modification and more tailored stroke risk assessment are top goals in managing atrial fibrillation

The new guideline emphasizes the importance of disease prevention, risk factor modification, and optimized therapies to manage atrial fibrillation. It also updates guidelines for catheter ablation, anticoagulants, and heart rate management, aiming to improve patient outcomes and reduce stroke risk.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateNov 30, 2023

What smoking does to oral bacteria

A study conducted by Eurac Research Institute found that cigarette use alters the oral microbiome, leading to an increased risk of periodontitis and cardiovascular disease. Quitting smoking results in a gradual increase in aerobic bacteria, which can lead to improved blood pressure regulation.

SourceEurac Research·JournalScientific Reports·TypeData/statistical analysis·DateNov 29, 2023

Coronary heart disease before age 45 may increase risk of dementia later in life

Research found a significant linear relationship between age of coronary heart disease onset and dementia, highlighting the detrimental influence of premature cardiovascular events on brain health. Adults diagnosed with coronary heart disease at a young age may be at increased risk of developing dementia, Alzheimer's disease, and vascu...

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateNov 29, 2023

Access remains the most serious barrier to cardiac rehabilitation

Despite its cost-effective prevention for recurrent events, cardiac rehabilitation remains inaccessible to many due to lack of social support, particularly in poorer countries. Home-based rehabilitation and comprehensive lifelong healthy behavioral programs may help address these barriers.

SourceElsevier·JournalCanadian Journal of Cardiology·TypeSystematic review·DateNov 28, 2023

Measuring long-term heart stress dynamics with smartwatch data

Biomedical engineers at Duke University created a new 'digital twins' framework using smartwatch data to capture personalized arterial forces over 700,000 heartbeats. This approach reduces the computational load by simulating tasks in parallel, enabling real-time tracking of cardiovascular disease progression and risk assessment.

SourceDuke University·TypeExperimental study·DateNov 27, 2023

Building a global, multi-disciplinary platform to promote women’s health: Global Centre for Asian Women’s Health

The Global Centre for Asian Women’s Health found that a Mediterranean diet rich in fruits, nuts, whole grains, and healthy fats can reduce the risk of gestational hypertension and preterm birth. The study also linked narrowing of retinal arterioles before conception to reduced fetal growth during pregnancy.

SourceNational University of Singapore, Yong Loo Lin School of Medicine·JournalAmerican Journal of Obstetrics and Gynecology·TypeSystematic review·DateNov 26, 2023

Younger people are more vulnerable to the effects of cardiovascular risk associated with high blood cholesterol and hypertension

A new study reveals that younger people are more vulnerable to the effects of high blood cholesterol and hypertension, atherosclerosis can be reversed if risk factors are controlled early enough. The study suggests aggressive control of cardiovascular risk factors at younger ages.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalJournal of the American College of Cardiology·TypeRandomized controlled/clinical trial·DateNov 20, 2023

Study reveals link between neighborhood environmental burden and risk of cardiovascular disease

A national study found that exposure to environmental hazards in neighborhoods is associated with poor cardiovascular health, particularly among socioeconomically disadvantaged communities. The study used the Environmental Justice Index to assess cumulative environmental burden and its impact on cardiovascular risk factors and diseases.

SourceBeth Israel Deaconess Medical Center·JournalJAMA Cardiology·DateNov 15, 2023

Neighborhood environmental burden and cardiovascular health

A study of US neighborhoods found a strong association between environmental burden and higher rates of cardiovascular risk factors and diseases. Socially vulnerable neighborhoods showed the strongest associations, highlighting the need for initiatives to address poor environmental conditions and improve cardiovascular health.

SourceJAMA Network·JournalJAMA Cardiology·DateNov 13, 2023

Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke

Scientists at the University of Leicester have made a groundbreaking discovery about how cholesterol in our diet is absorbed into our cells. The research, published in Science, highlights the role of two proteins called Aster B and Aster C in transporting cholesterol from the intestine to the bloodstream.

SourceUniversity of Leicester·JournalScience·TypeExperimental study·DateNov 13, 2023

Semaglutide delivers 20 percent reduction in major adverse cardiovascular events in patients with obesity but no history of diabetes

A 20% reduction in major adverse cardiovascular events has been observed for patients with obesity but no history of diabetes taking semaglutide. This study marks a significant milestone, demonstrating the cardiovascular benefits of semaglutide beyond its weight loss effects.

SourcePennington Biomedical Research Center·JournalNew England Journal of Medicine·DateNov 13, 2023

Decline in estimated glomerular filtration rate after dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

Patients with heart failure treated with dapagliflozin experienced frequent initial estimated glomerular filtration rate declines, but without increased cardiovascular or kidney event risks. The study suggests that sodium-glucose cotransporter-2 inhibitors can be safely continued in patients experiencing eGFR decline.

SourceJAMA Network·JournalJAMA Cardiology·DateNov 12, 2023

International clinical trial finds that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity who don’t have diabetes

A recent clinical trial found that semaglutide significantly reduced cardiovascular events in adults with overweight or obesity who do not have diabetes. The medication was shown to lower the risk of death from cardiovascular causes, nonfatal heart attacks, and strokes by 20% compared to placebo.

SourceCleveland Clinic·JournalNew England Journal of Medicine·DateNov 11, 2023

Increasing workplace flexibility associated with lower risk of cardiovascular disease

A new study found that workplaces implementing flexible work arrangements can reduce employees' cardiometabolic risk, equivalent to a reduction of 5-10 years in age-related changes. The intervention had no negative impact on productivity and was particularly beneficial for low- and middle-wage workers.

SourceHarvard T.H. Chan School of Public Health·JournalAmerican Journal of Public Health·TypeRandomized controlled/clinical trial·DateNov 8, 2023

Molecule tested at University of São Paulo, in Brazil, proves able to mitigate heart failure

Researchers at the University of São Paulo have tested a synthetic molecule called AD-9308, which has shown potential in treating heart failure by activating the enzyme aldehyde dehydrogenase 2. The study found that the molecule improved mitochondrial filtration, eliminating cellular pollutants and boosting heart function by up to 40%.

Study in JAMA Cardiology finds coating on aspirin does not impact effectiveness or safety for cardiovascular patients

A recent study in JAMA Cardiology analyzed data from 15,000 patients and found that enteric coating on aspirin does not change its effectiveness or safety for secondary prevention of cardiovascular events. The study suggests that patients can choose the aspirin formulation that suits them best.

SourceOchsner Health System·JournalJAMA Cardiology·TypeRandomized controlled/clinical trial·DateNov 6, 2023

Chinese Medical Journal study analyzes recent global and national trends of atherosclerosis

A recent study analyzing global and national trends of atherosclerosis found an increasing trend in incidence from 1990 to 2019, driven by adults aged 20–54. The burden of the disease is particularly concerning in low- and middle-income countries, where it is rising significantly due to lifestyle factors and aging populations.

SourceCactus Communications·JournalChinese Medical Journal·TypeData/statistical analysis·DateNov 2, 2023