Research on diseases of the heart and blood vessels. Covers microvascular imaging, light exposure, cardiac imaging anxiety, and sex differences in risk.
Long-term BMI variability was a significant risk marker for adverse cardiovascular events, independent of mean BMI, across major racial and ethnic groups. The study's findings have implications for the phenotype of high BMI variability and potential preventive measures.
A free, weekly home delivery program of fresh fruits and vegetables improved participants' nutrition levels, physical activity levels, and cardiovascular disease risk factors. The 16-week program resulted in significant improvements in food insecurity, diet quality, and indicators of cardiovascular health.
Preliminary research suggests that short-term heat exposure can lead to increased inflammation and impaired immune function, making individuals more susceptible to infections. Adults older than 60 and those with existing cardiovascular disease are particularly at risk.
Research found that certain patterns of pregnancy history, including early deliveries and multiple hypertensive disorders, are associated with high risk of heart attack and stroke. Others with fewer or no complications have lower risk, suggesting other factors may also play a role in predicting cardiovascular disease mortality.
People with dementia experience declines in social well-being as their disease progresses, while caregivers become isolated due to caregiving responsibilities. Experts recommend screening for loneliness and finding ways to keep individuals socially connected to improve quality of life and reduce health outcomes.
Researchers found that Black individuals carrying genetic variants in the Titin, TTN gene have a high risk of developing atrial fibrillation, heart failure, and dilated cardiomyopathy. The study used data from the All of Us Research Program to examine the role of these genetic mutations in African ancestry individuals.
A new JAMA article highlights the need for improved decision making prior to initiating lecanemab, an FDA-approved Alzheimer’s Disease drug, due to its potential side effects on patients with cardiovascular disease. The authors advocate for advanced care planning and shared decision-making models to guide treatment decisions.
Researchers identified six novel protein biomarkers associated with incident coronary heart disease in individuals with and without type 2 diabetes. The study found that these biomarkers may offer potential new approaches to prevention and treatment of CHD.
Researchers found that people who limited their eating to less than 8 hours per day were more likely to die from cardiovascular disease compared to those who ate for 12-16 hours. This contradicts previous research suggesting short-term benefits of time-restricted eating.
Research reveals that polyphenols interact with bitter taste receptors in the gut, promoting vasorelaxation, regulating blood pressure, and influencing hormone secretion. Bitter and astringent perception of polyphenols also affects HPA axis activation, improving mood and memory function.
Bruno Scheller developed a procedure using drug-coated balloons to treat coronary and peripheral artery disease, improving patients' quality of life. The technique has been widely recognized and effective, with countless patients spared further pain and surgery.
A new study published in the Journal of the Endocrine Society found significant cardiometabolic improvements in patients who underwent bariatric surgery, including lower blood pressure and cholesterol levels. The study analyzed over 7,800 patients and showed that younger females and whites experienced greater post-surgery cardiometabol...
A study by Linköping University found that a daily intake of liquorice containing 100mg glycyrrhizic acid raised blood pressure by an average of 3.1mmHg in young healthy people. This effect was seen in all participants, but the most sensitive individuals showed increased fluid volume and heart workload.
Researchers have made progress in understanding atherosclerosis, identifying potential new approaches for early detection and therapy. The study found that TREM2 regulates the activity of macrophages, playing an important role in forming unstable plaques that increase heart attack and stroke risk.
A new study reveals that adults living in extreme poverty in LMICs have high rates of hypertension, diabetes, smoking, obesity, and dyslipidemia, yet are often untreated for these conditions. The findings challenge the common assumption that poverty protection against cardiovascular disease risk factors.
A novel risk score predicts cardiovascular complications after bone marrow transplant with high accuracy, helping guide patient selection and post-transplant management. Patients with preexisting cardiovascular conditions are more likely to experience long-term complications.
A Japanese study published in JACC: Asia found that women with depression are at a greater relative risk of developing heart-related negative health outcomes compared to men. The study identified sex-specific factors contributing to the increased CVD risk and emphasized the need for targeted prevention and treatment strategies.
Researchers found that Kupffer cells in liver respond to high cholesterol by removing excess, revealing the liver's role in regulating cholesterol levels. This discovery suggests atherosclerosis is a systemic disease affecting multiple organs.
Researchers at UVA Health System have discovered genetic clues that may help identify people at risk of cardiovascular disease, including atherosclerosis. The study identified 20 locations on chromosomes that influence protein production, shedding light on why smooth muscle cells sometimes are beneficial and sometimes harmful.
Researchers developed a wearable device for non-invasive monitoring of hemodynamic indicators like heart rate, blood pressure, and oxygen saturation. The photoacoustic imaging watch offers valuable insights into disease diagnosis and treatment.
Researchers at the University of Virginia Health System are developing a technique to 'paint' tiny nanoparticles on transplanted veins to prevent blockages, potentially sparing patients from repeated surgeries. This approach could significantly reduce the number of vascular reconstructions performed annually in the US.
A new study found that more than half of American Indian teens had high levels of cholesterol, with nearly two-thirds of young adults experiencing the same issue. The study suggests a need for early screening and treatment to prevent premature heart disease.
A new poll suggests that more than half of people aged 50-80 taking aspirin don't have cardiovascular disease, raising concerns about the effectiveness of routine aspirin use. Guidelines now focus on those with a history of cardiovascular issues or high risk due to personal health and family history.
Researchers aim to address LVAD shortcomings, reducing blood damage and clotting risk through innovative designs and coatings. A novel flexible stented blood inlet and slippery hydrophilic coatings will be used to prevent flow stasis and clot formation.
A study funded by the National Institutes of Health found that more than 70% of American Indian young adults aged 20-39 and 50% of teens have abnormal or high cholesterol. High LDL cholesterol was linked to plaque buildup and cardiovascular events, emphasizing the need for early screenings and culturally relevant education.
A large population-based study found that taking 9000 to 10000 steps daily reduces death and cardiovascular disease risk in highly sedentary individuals. The optimal number of steps per day to counteract high sedentary time is between 4000 and 4500 steps/day, lowering mortality risk by 39% and incident CVD risk by 21%.
Women with complicated pregnancies are 2-5 times more likely to die of cardiovascular diseases later in life. A study found that a woman's total pregnancy history at 40 years of age is strongly associated with ASCVD mortality.
A study by the University of Exeter found that substituting meat for Quorn lowers bad cholesterol by 10-percent. This reduction is comparable to switching to a Mediterranean or vegan diet and has significant implications for heart health.
A large international clinical trial found that standard tools underestimate cardiovascular event risk in people with HIV, particularly in high-income regions and those with detectable viral loads. The study highlights the need for updated screening tools to provide precision care for the diverse population living with HIV.
The new guidelines recognize the aorta as an independent organ, bundling its treatment with other specialties. This holistic approach improves treatment outcomes for patients with aortic rupture and other serious diseases.
A modelling study suggests that mandatory menu calorie labelling in England could prevent approximately 730 deaths from cardiovascular disease between 2022 and 2041. If extended to all food businesses, this number could increase to around 9,200 deaths.
A new study found that frequent cannabis use is associated with a higher risk of heart attack and stroke, even after controlling for tobacco use and other cardiovascular risk factors. The study analyzed data from over 430,000 adults in the US and found that smoking cannabis was significantly linked to cardiovascular risks.
A new American Heart Association scientific statement highlights the value of AI technology in improving cardiovascular disease patient outcomes. Despite its potential, AI applications face gaps and challenges, including robust clinical validation and addressing biases.
A study analyzing ELSA data found that osteoporosis, heart disease, and poor hearing increased frailty risk in men, while high fibrinogen levels, diabetes, and stroke were linked to higher risks in women. This highlights the importance of gender-specific action plans and intervention for older people.
Researchers identified six blood biomarkers associated with increased cardiovascular risk in patients with rheumatoid arthritis. These biomarkers improved the ability to predict arterial inflammation, an indicator of cardiovascular risk, compared to standard clinical indices.
A study by UC San Francisco researchers found that daily cannabis users had a 25% increased risk of heart attack and a 42% increased risk of stroke compared to non-users. The study also found significant cardiovascular risks associated with cannabis use, including coronary heart disease and the combination of heart attack and stroke.
A new study published in the Journal of the American Heart Association found that older women who sat for 11.7 hours or more per day increased their risk of death by 30 percent. The study used machine-learned algorithm CHAP to examine total sitting time and length of sitting bouts.
New research reveals women's cardiovascular disease risks differ by age, lifestyle factors, and mental health conditions. Studies show sedentary behavior increases risk of death from all causes, while preeclampsia is linked to diet, highlighting need for targeted prevention strategies.
A recent Mayo Clinic study found that daylight saving time has a minimal impact on heart health. Researchers analyzed data from 36 million adults and found a slight increase in cardiovascular events during the spring and fall transitions, but this was deemed clinically insignificant.
A new study finds that everyday discrimination can drive unhealthy coping behaviors like smoking, leading to increased heart disease risk. Research highlights the importance of considering multiple identities when studying health disparities and creating interventions.
Researchers developed scSNV-seq to investigate genetic changes affecting gene activity and disease development. The technique accurately assesses the impact of thousands of DNA mutations in cells, providing crucial insights for developing targeted therapies.
Canadian healthcare leaders call for re-establishment of a national hypertension control program to reduce deaths and disabilities. The program aims to provide population-scale prevention methods, proven to save lives and reduce healthcare costs. Experts highlight the need for collaboration with governments and healthcare providers.
The Almodóvar lab is studying the link between HIV and pulmonary hypertension, a condition that increases pressure in lung arteries. By examining the interactions between different cell types and using a humanized mouse model, researchers hope to propose novel therapies to prevent lung diseases in people with HIV.
A new study reveals that genetic variants associated with hypertension can increase the risk of high blood pressure from as early as three years old. By analyzing health data from large population studies, researchers found that these genetic factors can significantly affect blood pressure levels throughout life and even beyond adulthood.
A recent study from Brigham and Women's Hospital found that a glycan biomarker of IgG is an important predictor for cardiovascular diseases. The research team discovered that the sugar coatings on IgG were directly related to the risk of a CVD event, most likely through inflammatory effects.
A study found that 2-methylbutyrylcarnitine (2MBC), a gut microbial metabolite, exacerbates thrombosis and is accumulated in COVID-19 patients. Elevated 2MBC levels are associated with increased blood clot risk, suggesting a potential mechanism linking gut microbiota dysbiosis to cardiovascular disease.
A Swedish study of over 9,000 men found that those who were physically fit in adolescence had a lower risk of atherosclerosis nearly 40 years later. The researchers used advanced imaging technology to examine plaques in the coronary arteries and found associations with both good cardiorespiratory fitness and muscle strength in youth.
New research from the University of California San Diego found that men with a higher area of abdominal muscle have a greater risk of cardiac trouble. Men with the densest muscle in their abdominal cavity had about one quarter the risk of coronary heart disease later on.
A new study found that severe maternal grief, particularly the loss of a partner or child, is associated with an increased risk of heart failure in children up to middle age. The research suggests that prenatal stress may lead to adverse changes in mental and physical health, impacting fetal heart development.
A study published in PLOS ONE found that raised blood pressure has been the leading risk factor for death in Australia for three decades, contributing to at least 44% of cardiovascular disease (CVD) deaths. The research highlights the importance of prioritizing blood pressure control efforts in public health agendas.
A new study found that chronic exposure to PM2.5 is associated with increased risk of hospital admission for various cardiovascular conditions, particularly ischemic heart disease and cerebrovascular disease. The study suggests that lowering annual average PM2.5 levels could decrease overall cardiovascular hospitalizations by 15%.
A one-year interdisciplinary therapy program reduced inflammation and cardiometabolic risk in obese adolescents, improving insulin resistance and weight management. The semi-intensive model produced better results than previous intensive models, reversing hyperlipidemia and promoting energy balance.
A new study suggests that finasteride, a common hair loss and prostate drug, may also lower cholesterol levels and reduce cardiovascular disease risk in men. In mice, the researchers found significant correlations between finasteride use and lower cholesterol levels, as well as reduced inflammation and atherosclerosis progression.
A recent study by Cleveland Clinic researchers discovered a connection between elevated niacin levels and an increased risk of heart disease. The study found that high levels of 4PY, a breakdown product from excess niacin, were strongly linked to the development of heart attacks and strokes.
Researchers discovered that consuming over 22% of daily calories from protein can lead to increased activation of immune cells contributing to atherosclerotic plaque formation. Leucine, an amino acid found in animal-derived foods, plays a disproportionate role in driving pathological pathways linked to atherosclerosis.
A major new study reveals that heart attack survivors are at high risk of developing further serious health conditions, including heart failure, kidney disease, and depression. The research found that up to a third of patients developed heart or kidney failure, and 38% died within nine years.
Rats fed high-fructose diets exhibit disturbances in autonomic nervous and cardiovascular systems, increasing risk of chronic diseases like diabetes and obesity. Fructose consumption by parents is also associated with impaired physiological regulation of their offspring's cardiovascular system.
A new American Heart Association scientific statement emphasizes the need for increased awareness of heart disease as a major health risk for women, particularly those with pregnancy complications. Early detection and treatment of risk factors may help prevent future heart attack, heart failure, and stroke.
The new advisory highlights the dramatic advances in understanding and treatment of cardiovascular diseases over the past century. These advancements have saved millions of lives and reduced heart disease death rates by more than half since 1950.
A new study found that physical activity levels are insufficient to counter the increased risk of cardiovascular disease associated with consuming sugar-sweetened beverages. Even moderate consumption can lead to higher cardiovascular disease risk, emphasizing the need to limit these drinks' omnipresence in the food environment.