Articles tagged with Cardiovascular Disease
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The Lehigh University team created a computational model to predict the hemodynamic response of patients with AFib, helping tailor neurostimulation dosages. The model validated against clinical data and predicted accurate effects on blood pressure, heart rate, and stroke volume.
A novel post-translational modification, lactylation, plays a critical role in the pathogenesis of aortic dissection. Lactylation of mitochondrial adenosine triphosphate synthase subunit alpha impairs ATP production and increases reactive oxygen species generation.
A large international study found that utilizing sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine DES implantation for treating de novo coronary artery disease. The results showed comparable outcomes, including low rates of cardiac death and target vessel myocardial infarction.
A prospective cohort study found that individuals who accumulate their daily steps in longer bouts have a lower risk of mortality and cardiovascular disease. In sedentary participants, the association between longer stepping bouts and lower risk was more pronounced.
The American Heart Association launches a new certification program to equip healthcare providers with digital tools to manage chronic conditions remotely. The certification aims to standardize training and validate expertise in delivering care in technology-enabled clinical settings, promoting better patient engagement and outcomes.
The study found that cutting balloon angioplasty is noninferior to intravascular lithotripsy in treating calcified coronary artery disease. The procedure is also less costly, making it a reasonable strategy for managing significantly calcified lesions.
The Cardiovascular Research Foundation (CRF) has announced the 2025 SET-10 Rankings, honoring institutions whose groundbreaking research is shaping the future of cardiovascular care. The rankings recognize academic and medical institutions that are advancing the science and improving patient outcomes.
A cohort study found that night light exposure was a significant risk factor for developing cardiovascular diseases among adults over 40. Avoiding light at night may be a useful strategy for reducing the risks of cardiovascular diseases.
A new study published in The Lancet found that semaglutide, a 'weight loss' drug, can help prevent heart attacks and other major cardiac events, regardless of the amount of weight people lose. The study suggests there are multiple ways the drug benefits the heart, beyond its protective effect on cardiovascular health.
A large-scale cohort study found that stopping drinking even at low levels can lead to clinically meaningful reductions in blood pressure. Researchers analyzed data from over 359,000 adults and discovered that quantity of alcohol intake is the primary driver of blood pressure changes.
A Northwestern University study found that Chicago parents have low intake of omega-3 fatty acids, specifically EPA and DHA, with women consuming even lower amounts. This deficiency may have direct negative effects on children's health, including preterm birth risk.
The American Heart Association found that nearly 9 in 10 US adults haven't heard of CKM syndrome, a condition affecting heart disease, kidney disease, diabetes, and obesity. The association is providing resources to help people understand the connection between heart, kidney, and metabolic health.
Mike Leach, the mastermind of the air raid offense, will be recognized posthumously for his exceptional contributions to college football. The American Heart Association's Paul “Bear” Bryant Heart of a Champion Award honors Leach's larger-than-life impact on the game and communities he touched.
A recent study found that fish oil supplements can lower cardiovascular disease risk even in healthy individuals, with effects varying greatly between people. The study showed that EPA supplementation improved blood lipid profiles and reduced lipoprotein attachment to arterial walls.
Researchers found that diets rich in plant-based products of higher nutritional quality, with little or no industrial processing, were associated with a 40% lower risk of cardiovascular disease. In contrast, ultra-processed plant-based foods showed no protective effect.
This study found that GLP-1RAs and SGLT2is offer the greatest cardiovascular benefits for adults with type 2 diabetes. The magnitude of benefit depends on baseline age, atherosclerotic cardiovascular disease, heart failure, and kidney impairment.
The 2025 Cardiovascular Provider Compensation and Production Survey found a 21% increase in cardiovascular providers represented, with data from 232 programs submitted. The report highlights adaptations in care delivery, including a drop in physician FTEs per 1,000 active patients as apps assume more responsibility.
The American Heart Association has released its 2025 Coach of the Year Award watch list, featuring 28 college football coaches. The award, presented annually, recognizes coaching excellence that promotes grit, integrity, and a winning approach to both on-field performance and off-field life.
The analysis of 2024 English voting patterns suggests that poorer health is associated with higher proportions of votes for Reform UK. This finding highlights the need for policymakers to address health inequalities and improve public health.
Phillip Fulmer, legendary University of Tennessee football coach, is the recipient of the American Heart Association’s 2026 Paul “Bear” Bryant Lifetime Achievement Award. The honor recognizes his outstanding career achievements and contributions to the sport.
Researchers developed a new model to predict risk of subsequent cardiovascular events in patients with ASCVD, outperforming current guidelines. The novel scoring tools use readily available clinical factors and blood assays, enabling easier, faster clinical translation.
The American College of Cardiology has launched a new education program to educate clinicians on the latest advances in heart failure management and treatment. The program aims to improve outcomes among patients with heart failure by providing education on tailored treatments for different subtypes of HF.
Researchers use AI, omics, and systems biology to design targeted drugs for cardiovascular disease pathways. The tools could transform heart drug development and save lives, but global health policy leadership is urgently needed.
A prospective cohort study found that young adults experiencing unfavorable patterns of cardiovascular health are at a marked increased risk for incident cardiovascular disease. Achieving and maintaining high cardiovascular health throughout young adulthood is crucial for preventing later-life cardiovascular disease.
Dr. Nicole Bhave has been named the ACC Annual Scientific Session vice chair and will lead the development of the educational program at ACC.27 and ACC.28. She also serves as a two-year meeting chair from ACC.29 to ACC.30.
The review highlights the critical roles of phospholipids in regulating immune cell migration, differentiation, and survival, as well as their regulatory effects on inflammation. Dysregulated phospholipid metabolism is linked to various diseases, including autoimmune disorders, cardiovascular disease, and cancer.
The American Heart Association has acquired the Cardiometabolic Center Alliance program, strengthening efforts to provide holistic management of cardiovascular, kidney, and metabolic health. This partnership aims to expand patient-centered care and improve outcomes for patients with cardiometabolic disease.
Dr. Judith Hochman will receive the 2025 Research Achievement Award for her significant research on revascularization and women's cardiovascular health. Her work has directly impacted clinical practice guidelines, particularly in ischemic heart disease.
A phase 3 clinical trial found that sotatercept significantly reduces the likelihood of worsening disease in patients with severe pulmonary hypertension when added to standard treatment within the first year after diagnosis. The medication reduced the risk of deterioration by 76% and hospitalizations by nearly half.
The American College of Cardiology has released a scientific statement on inflammation and its connection to various cardiovascular diseases, including coronary artery disease and heart failure. The statement confirms years of research confirming the importance of inflammation as an underlying contributor to CVDs.
Dr. Megan McLaughlin's research highlighted critical gaps in postpartum care for individuals with hypertensive disorders of pregnancy, a major risk factor for future cardiovascular disease. Her study confirms missed opportunities to improve long-term heart health in a high-risk population.
A prospective cohort study found an AI tool accurately assesses body composition from routine MRI, identifying patients at high cardiometabolic risk. Associations were strongest with visceral adipose tissue proportion and skeletal muscle fat fraction.
The SHC-SHG program leads to a 16% reduction in LRDs among self-employed individuals, while unemployed individuals show significant behavioral changes but not health improvements. The increase in municipal funds is found to be cost-effective, with overall medical expenses reduced by nine times the increase.
The latest Global Burden of Disease study reveals a significant increase in cardiovascular disease (CVD) burden worldwide, with CVD causing one in three deaths globally. The report estimates that 79.6% of all CVD deaths are attributable to modifiable risk factors, which has increased globally by 97.4 million since 1990.
A binational study found nearly 6 in 10 US adults and 3 in 10 Japanese adults discontinued semaglutide within 12 months of treatment. Patients with established cardiovascular disease and chronic kidney disease had higher discontinuation rates, highlighting the need for alternative treatments.
A new study found significant racial disparities in the care of patients with ST-elevation myocardial infarction (STEMI) in Florida. Hispanic and non-Hispanic Black patients were less likely to receive percutaneous coronary intervention (PCI), a recommended treatment, compared to non-Hispanic white patients. This disparity resulted in ...
The Global Burden of Disease (GBD) 2023 study presents the most up-to-date data for 204 countries and territories, highlighting trends in cardiovascular disease. The study supports progress toward the United Nations Sustainable Development Goals, particularly SDG 3.4, by providing critical health data.
New research finds that GLP-1 receptor agonists (GLP-1RAs) significantly reduce the risk of death and major cardiovascular events in psoriasis patients. GLP-1RAs also show promise in reducing alcohol and substance abuse, with a 65% lower risk of alcohol abuse.
A new machine learning model predicts heart disease risk in women by analyzing mammograms, offering a 'two-for-one' screening approach that combines breast and cardiovascular screenings. The model performs comparable accuracy to traditional risk calculators without requiring extensive clinical data.
A new AI algorithm using routine mammogram images and age can predict major cardiovascular disease risk as accurately as standard methods. The study suggests that mammography may offer a cost-effective 'two for one' effective screening option for women, leveraging existing health infrastructure.
The TCT AI Lab equips clinicians with skills to integrate AI into clinical practice, advancing precision, efficiency, and patient outcomes. The initiative is made possible by a generous grant from the Jon DeHaan Foundation.
Researchers identified a long non-coding RNA called CARMN as a surprising new treatment target for chronic limb-threatening ischemia. The study found that blocking the protein HHIP, controlled by CARMN, improves blood flow and tissue healing in patients with CLTI.
An AI algorithm based on routine mammogram images plus age can predict a woman's risk of major cardiovascular disease with high accuracy. The algorithm leverages existing health infrastructure and offers a cost-effective 'two for one' screening option.
Dr. Collet joins CRF to accelerate integration of cutting-edge research into clinical practice and expand global leadership in cardiovascular education. He will lead efforts to unify translational science, technological innovation, and education.
High consumption of ultra-processed foods is associated with higher levels of systemic inflammation and a greater risk of cardiovascular disease. The study found that individuals who consumed the most ultra-processed foods had significantly higher levels of high-sensitivity C-reactive protein, a key marker of inflammation.
Researchers found that neutrophil protein Relmy pokes holes in heart cells, promoting dangerous heart rhythms and cell death. The study suggests targeting immune cells may help prevent sudden cardiac death and arrhythmias.
A large sample of U.S. children born between 1959 and 1966 showed a consistent association between higher blood pressure at age 7 and greater risk of premature cardiovascular disease mortality. The findings are supported by similar associations found in siblings, reducing concerns about confounding factors.
A study published in Annals of Translational Medicine found that intense light therapy can lower troponin levels and increase ANGPTL4 protein, protecting heart tissue. The treatment may reduce the risk of myocardial injuries after non-cardiac surgery, which affects 20% of patients and increases one-year mortality rates.
Researchers found that methotrexate significantly lowers systolic blood pressure in people with rheumatoid arthritis. The study suggests that this could be a new benefit of the drug beyond its usual role in treating inflammation, and may also provide protection against heart disease.
A new hypothesis proposes that transformation of adipokine molecules in excess internal fat tissue is the primary cause of heart failure with preserved ejection fraction (HFpEF). Drugs targeting fat tissue, not the heart, can alleviate HFpEF symptoms.
Researchers found that women with high hsCRP levels had a significantly increased lifetime risk of coronary heart disease, stroke, and major cardiovascular events. Statin therapy can help reduce risk among these individuals by 38%.
A subanalysis of the LoDoCo2 trial found that low-dose colchicine slows the growth of clonal hematopoiesis, a common acquired gene mutation linked to cardiovascular disease and cancer. Colchicine was associated with significantly attenuated clonal growth in TET2-mutated CH.
Researchers have successfully treated damage caused by heart attacks in non-human primates using gene therapy, restoring both strength and rhythm of the damaged hearts. The treatment improved heart function in pathological conditions with no adverse effects observed.
A new online calculator helps doctors determine the most effective treatment plan for each patient based on their blood pressure needs. By categorizing treatments as low, moderate, or high intensity, the tool enables personalized treatment plans and potentially improves patient outcomes.
A new study found that automatic chest compression devices can effectively perform CPR on a floating manikin, reaching depths of up to 53mm. This finding contradicts current NASA emergency protocols and suggests space agencies may need to reconsider their guidelines for treating cardiac arrest in space.
Late-breaking clinical trials and science at TCT 2025 will present pivotal data on novel therapies, devices, and techniques aimed at preventing and treating cardiovascular conditions. The symposium delivers high-impact findings that shape clinical practice and enhance outcomes for patients with heart and vascular disease.
The American College of Cardiology recommends flu, COVID-19, RSV vaccinations and others for adults with heart disease to reduce risks of infection, hospitalization, and death. Vaccination has been shown to be highly effective in reducing these risks, yet only 30% of primary care physicians assess patients' vaccination status.
A new study found that genetic variants in the IL6 gene are associated with a reduced lifetime risk of coronary heart disease, stroke, and peripheral artery disease. These variants also reduce the risk of pneumonia and sepsis, countering fears about impaired immune response.
A new study found that younger men with type 2 diabetes are more likely to experience worse cardiovascular disease and mortality outcomes compared to those with type 1 diabetes. In contrast, women with type 1 diabetes face poorer health outcomes across all ages, particularly due to longer exposure to high blood sugar levels and less ag...
Research shows that cardiovascular health scores among older adults with high blood pressure, stroke, or heart failure decreased significantly. The study analyzed data from the US National Health and Nutrition Examination Survey, finding that physical activity and blood pressure scores were low for those with cardiovascular disease.