Cerebrovascular Disorders
Articles tagged with Cerebrovascular Disorders
Intravenous tenecteplase prior to endovascular treatment for ischemic stroke at 4.5 to 24 hours
One protein, two roles
Researchers found that Adgrl2 plays a crucial role in building both brain synapses and blood vessels, with different cell types producing distinct versions of the protein. Removing Adgrl2 from endothelial cells caused blood vessels to become leaky and lose their integrity.
Low-dose triple-pill cut risk of recurrent stroke by about 40%, global trial shows
A global trial involving 1,670 patients with intracerebral haemorrhage found that treatment with a single pill combination of three low-dose blood pressure medicines reduced the risk of another stroke by 39%. The study showed significant benefits in reducing major cardiovascular events and improving blood pressure control.
Influenza vaccine could protect against heart attack and stroke even among people who get infected
Researchers found that influenza vaccination reduced the risk of heart attack and stroke by half for those who got infected, even if they didn't get vaccinated beforehand. The study's findings suggest prioritizing influenza vaccination among high-risk populations could have significant public health impact.
Stroke: Promising GPVI inhibitor takes an important step toward clinical development
Boehringer Ingelheim and EMFRET Analytics have partnered to advance the GPVI-blocking antibody EMA601 for acute stroke treatment. The substance targets platelet surface receptor glycoprotein VI, blocking thrombosis and inflammation while preserving normal blood coagulation.
USC study identifies brain rewiring mechanism that may aid stroke recovery
Researchers discovered that stroke survivors with severe motor impairment show signs of brain 'youthfulness' in undamaged regions, suggesting the brain's ability to adapt and compensate. This finding provides new insights into neuroplasticity and may guide personalized rehabilitation strategies.
Home-based program slashes post-stroke falls rate by 33%
A new Australian study shows that a tailored, home-based program can significantly reduce the number of falls after stroke. The 'falls after stroke trial' (FAST) found that the program reduced falls by 33% over 12 months.
Functional photoacoustic microscopy reaches super-resolution by tracking red blood cells
Researchers developed a high-speed photoacoustic microscope to track red blood cells in the mouse brain, allowing for single-cell resolution imaging of microvascular structures. This enables study of cerebral small vessel disease, cognitive impairment and dementia.
Association of dual eligibility and medicare type with quality of postacute care after stroke
Patients who are dual-eligible for Medicare and Medicaid, or enrolled in Medicare Advantage plans, are less likely to receive high-quality postacute care after a stroke. This disparity highlights the need for equitable access to specialized care to improve outcomes for high-need patients.
FAU study links ultra-processed foods to greater heart attack, stroke risk
A study by Florida Atlantic University found that ultra-processed foods (UPFs) are associated with a 47% higher risk of cardiovascular disease. Researchers analyzed data from the US National Health and Nutrition Examination Survey and found that those consuming high amounts of UPFs had a significant increase in heart attack and stroke ...
Tenecteplase for acute non–large vessel occlusion 4.5 to 24 hours after ischemic stroke
Intravenous tenecteplase administered 4.5 to 24 hours after ischemic stroke non–large vessel occlusion improved functional outcomes at 90 days compared to standard care. However, it also increased the risk of symptomatic intracranial hemorrhage.
Life-course psychosocial stress and risk of dementia and stroke in middle-aged and older adults
Adverse experiences throughout life increase dementia and stroke risks, with depression as a mediating factor. Implementing life-course interventions addressing psychological trauma and mental health can reduce neurovascular disease burden.
Smoke from wildfires linked to 17,000 strokes in the US alone
Research links long-term exposure to wildfire smoke with increased risk of stroke in US adults, estimating around 17,000 annual cases. The study suggests wildfire smoke may be more harmful than pollution from other sources, and highlights the need for preventative measures.
Study finds brain care score can predict risk of stroke across racial groups
A new study from Mass General Brigham found that the Brain Care Score is a strong predictor of stroke across different racial groups in the US. Higher scores indicate healthier behaviors and lower risk of age-related brain diseases, including stroke.
Calcium in breast arteries predicts future cardiovascular disease
A new study found that calcium accumulation in breast arteries and its progression on mammograms can predict future cardiovascular disease. Women with more severe calcification and those whose calcification worsened over time had a higher risk of heart-related events, such as heart attack, stroke, and death.
Older age, chronic kidney disease and cerebrovascular disease linked with increased risk for paralysis and death after West Nile virus infection
A study published in JAMA Network Open found that older adults with chronic kidney disease or cerebrovascular disease are at double the risk for developing neuroinvasive West Nile virus infection, which can lead to paralysis and death. The study identified several risk factors, including male sex, immune suppressants, and multiple scle...
Heavy energy drink intake may pose serious stroke risk, doctors warn
A case report warns that heavy energy drink consumption may pose a serious stroke risk due to high caffeine and sugar content. The study highlights the potential cardiovascular risks associated with energy drinks and proposes increased regulation of sales and advertising campaigns to protect public health.
New study overturns assumptions about AFib treatment in sleep apnea patients
A new Tulane University study suggests that catheter ablation delivers major benefits for patients diagnosed with both atrial fibrillation and obstructive sleep apnea, significantly lowering the risks of heart failure and death. The study found a 40% drop in major cardiovascular events and a 70% decline in all-cause mortality.
US burden of disorders affecting the nervous system
A cross-sectional study found that US population faces significant challenges with nervous system disorders, impacting 180.3 million people, mainly due to stroke, Alzheimer's disease, diabetic neuropathy, and migraine conditions.
Poorer heart health in middle age linked to increased dementia risk
A new study found that middle-aged people with higher levels of cardiac troponin I in their blood were more likely to develop dementia in later life. The study also found that damage to the brain seen in people with dementia accumulates slowly over decades before symptoms develop.
USC-Caltech study moves novel tool to measure brain blood flow closer to the clinic
Researchers from USC Neurorestoration Center and Caltech created a simple, noninvasive device using laser technology to measure brain blood flow. The tool has already been tested with humans in small proof of concept studies demonstrating its utility for assessing stroke risk and detecting brain injury.
Research Spotlight: Mapping overlooked challenges in stroke recovery
Stroke survivors' lived experiences reveal key factors that shape their physical and emotional wellbeing during recovery. The study highlights the importance of integrating lived experiences in stroke research to improve care models.
AI body composition measurements can predict cardiometabolic risk
A new study found that AI tool accurately captures details in just three minutes from a body scan, highlighting the potential of using AI to repurpose data from routine scans. Visceral adipose tissue volume and fat deposits in muscle are strongly associated with diabetes and cardiovascular disease risk.
Vascular disease is an overlooked contributor to dementia, UNM researcher finds
A UNM researcher has identified 10 disease processes that contribute to vascular-based brain injury, including effects of nano- and microplastics. The findings suggest a potential half of Alzheimer's patients may also have vascular disease, paving the way for new classification and treatment approaches.
Revised diagnostic criteria for vascular cognitive impairment and dementia—The VasCog-2-WSO criteria
The VasCog-2-WSO criteria update provide operationalization and guidance on neuroimaging and fluid biomarkers for VCID diagnosis. This new standard aims to facilitate diagnostic consistency among clinicians and researchers worldwide.
Stem cell transplant for stroke leads to brain cell growth and functional recovery in mice
A study led by Keck School of Medicine of USC found that a stem cell transplant performed one week after an ischemic stroke in mice led to significant brain cell growth and functional recovery. The treated mice showed improved fine motor skills, gait, and reduced inflammation compared to untreated mice.
Stem cells repair mouse brains post-stroke
Stem cell transplantation has been shown to reverse stroke damage in mice by regenerating neurons and restoring motor functions. The treatment also improved blood-brain barrier integrity, reduced inflammation, and promoted new blood vessel formation.
Inflammation may explain why women with no standard modifiable risk factors have heart attacks and strokes
Researchers found that women with high hsCRP levels had a significantly increased lifetime risk of coronary heart disease, stroke, and major cardiovascular events. Statin therapy can help reduce risk among these individuals by 38%.
In utero brain surgery for Vein of Galen Malformation shows continued promise in new JAMA report
New data published in JAMA provides further evidence for fetal embolization as a potential treatment for Vein of Galen Malformation. Outcomes show a dramatic reduction in mortality to 43% and no neurodevelopmental delay among treated patients.
Stroke center certification and within-hospital racial disparities in treatment
A cohort study found that stroke center certification decreases racial disparities in treatment for white patients within the same hospital, but such disparities remain for Black patients. This suggests continued systemic inequalities in stroke care settings.
New discovery reveals the spinal cord’s role in bladder control
A USC research team has made a groundbreaking discovery about the human spinal cord's role in bladder control. The study used functional ultrasound imaging to observe real-time changes in blood flow dynamics during bladder filling and emptying, revealing areas where activity is correlated with bladder pressure.
Neurodegeneration and stroke after GLP-1RAs in diabetes and obesity
A cohort study found that GLP-1RAs like semaglutide and tirzepatide lower risk of dementia, stroke, and all-cause mortality in adults with type 2 diabetes and obesity. The findings suggest potential neuroprotective benefits beyond glycemic control.
Common sugar substitute shown to impair brain cells, boost stroke risk
A new study suggests that erythritol, commonly used in low-carb products, can alter the function of brain microvascular endothelial cells, leading to increased risk of stroke. The sugar substitute was found to constrict blood vessels and reduce the production of natural clot-busting compounds.
Hidden danger: Study maps rise of cardiovascular-kidney-metabolic syndrome in the U.S.
A recent study by Tarang Parekh reveals that 80% of US adults show signs of CKM syndrome, which increases the risk for cardiovascular disease. The condition progresses in stages, with stage 4 being the most dire, characterized by clinical CVD diagnoses such as heart failure and kidney failure.
Early blood-thinning treatment safe and effective for stroke patients
A new study published in The Lancet found that starting direct oral anticoagulants within four days of a stroke significantly reduces the risk of another stroke due to bleeding or artery blockage. Early treatment also did not increase the risk of bleeding into the brain.
Virtual reality could help stroke survivors regain movement
A Cochrane review found that virtual reality (VR) can help stroke survivors regain arm movement and increase therapy time. VR may also improve balance and reduce activity limitations, but effects on mobility and quality of life are uncertain.
OneCareAI, BSC's new spin-off to transform stroke prevention through AI and smartwatches
OneCareAI applies AI and supercomputing to detect early stroke risk from ECG data obtained with smartwatches, offering a non-invasive solution for personalized risk assessments. The technology has the potential to be extended to other cardiovascular diseases, opening opportunities for scalability.
Less frequent stroke monitoring is safe, effective, and frees up resources, study finds
Researchers found that halving vital sign and neurological function checks in low-risk patients after acute ischemic stroke treatment does not compromise care or recovery. The approach also frees up nursing time and intensive care resources, improving hospital capacity.
TCT 2025 Career Achievement Award to be presented to Stephan Windecker, MD
Stephan Windecker, a world-renowned cardiologist, will be honored with the TCT 2025 Career Achievement Award for his extraordinary contributions to interventional cardiology. His extensive research has shaped clinical practice worldwide and influenced the future of cardiovascular medicine.
New USC study identifies key brain networks behind post-stroke urinary incontinence
A new USC-led study using fMRI reveals the neural mechanisms that contribute to urinary incontinence in stroke survivors. The research found significant differences in brain activity during voluntary versus involuntary bladder contractions, presenting potential pathways for targeted therapies.
Could the falcine sinus hold the key to vein of Galen outcomes?
Researchers found larger falcine sinus diameters associated with higher risks of developmental delays, neurological issues and mortality in infants born with VOGM. Fetal MRI can help predict short- and intermediate-term outcomes, enabling early intervention and better care for high-risk patients.
Landmark review maps complex interactions between sex hormones and neurological health
A comprehensive review published in Brain Medicine maps out the extensive influence of reproductive hormones on neurological health and disease. The study examines how sex hormones affect a broad spectrum of neurological conditions, including vascular disorders, movement disorders, epilepsy, multiple sclerosis, and Alzheimer's disease.
A new approach to detecting Alzheimer’s disease
Researchers at Lancaster University have developed a new method to detect Alzheimer's disease by analyzing changes in brain oxygenation dynamics and neuronal function. The study found that individuals with Alzheimer's disease exhibit altered respiratory frequency, which may be an early indicator of the condition.
Adult children of divorced parents at higher risk of stroke
A recent study by researchers from the University of Toronto found that older adults who experienced parental divorce during childhood have a 60% higher odds of stroke. The study controlled for known risk factors and still showed a strong association between parental divorce and stroke.
Blood transfusions for brain bleeding: Large trial in aneurysmal subarachnoid hemorrhage patients adds to debate about optimal threshold
A large trial has found no major difference in clinical outcomes between restrictive and liberal blood transfusion strategies for critically ill patients with aneurysmal subarachnoid hemorrhage. The study suggests that integrating these results with other research can provide a deeper understanding of the optimal threshold.
People with migraine at high risk of depression during pandemic
A recent longitudinal study from the University of Toronto reveals that older adults with migraine are at a substantial increase in risk of depression during the pandemic. Increased family conflict, difficulties in accessing healthcare, and caregiving responsibilities were associated with higher risks of depression among this population.
What’s chubby enough for lower disability after stroke?
A recent study published in Topics in Stroke Rehabilitation found that slightly overweight stroke survivors (BMI 22.1-27.5 kg/m²) have a lower risk of sustaining disabilities compared to those with normal weight. The research suggests that a higher-than-normal BMI may be beneficial for recovering from a stroke with less disability.
New research confirms that young adults can also have large vessel occlusion strokes thought to happen in older adults, given the rise of stroke risk factors in younger adults
New research confirms that young adults are at risk for large vessel occlusion acute ischemic strokes, which were previously thought to occur mainly in older adults. The study found that nearly 20% of a cohort of 1,200 young adult patients had these strokes, highlighting the need for regular check-ups and prompt treatment.
Native Hawaiian and Pacific Islander adults have third highest cardiovascular death rate in the U.S.
A nationwide mortality data study found Native Hawaiian Pacific Islander (NHPI) adults have the third highest cardiovascular death rate in the US, with approximately 40% of deaths attributed to coronary heart disease. The study highlights a need for focused interventions to promote cardiovascular health among NHPI adults.
USC-Caltech team tests new noninvasive tool to predict stroke risk
A team of researchers from USC and Caltech developed a new noninvasive tool to measure brain blood pressure, assessing stroke risk through changes in blood flow and volume during a stress test. The affordable, portable device has the potential to transform stroke care by providing more reliable data than existing questionnaires.
Stroke recovery: It’s in the genes
Researchers found specific gene variants associated with behavioral health outcomes after a stroke. The study suggests that genetic differences may predict stroke recovery trajectory, enabling personalized medicine approaches for individualized treatment.
Chronic loneliness may increase stroke risk among older adults
A new study by Harvard T.H. Chan School of Public Health found that chronic loneliness may significantly raise the risk of stroke among older adults. The research suggests that loneliness, experienced chronically, plays an important role in stroke incidence and is associated with a higher risk of long-term disability and mortality.
International experts reach consensus on the labeling of spatial neglect
A consensus has been reached by an international team of rehabilitation researchers and clinicians on the standardized labeling of spatial neglect, a common disorder following neurological injury. The panel adopted 'spatial neglect' as the standard term for the disorder, aiming to improve diagnosis, treatment, and research.
Very early blood pressure control confers both benefits and harms in acute stroke
A new study found that very early blood pressure lowering treatment can improve outcomes for patients with intracerebral hemorrhage, but worsen outcomes for those with ischemic stroke. Rapid diagnosis of the type of stroke is crucial in harnessing the benefits of this treatment.
TCT® 2024 Master Operator Award to be presented to Jeffrey W. Moses, MD
Jeffrey W. Moses, MD, is recognized for advancing the field of interventional cardiovascular medicine through technical excellence and leadership. Dr. Moses has performed over 20,000 interventional procedures and made significant contributions to clinical research and educational activities in interventional vascular therapy.
New study reveals age-related brain changes influence recovery after stroke
A groundbreaking study found that areas of age-related damage in the brain relate to motor outcomes after a stroke, suggesting other factors are at play. White matter hyperintensities were associated with more severe motor impairment, independent of corticospinal tract damage.
A blood test for stroke risk? Study finds network of inflammatory molecules may act as biomarker for risk of future cerebrovascular disease
Researchers at UCLA Health have developed a potential biomarker for stroke risk using a network of inflammatory molecules in the blood. The study, published in the journal Stroke, found that patients with higher concentrations of these molecules had an 84% chance of experiencing a stroke during their lifetime.
Robotic hip exoskeleton shows promise for helping stroke patients regain their stride
A portable robotic device has been developed to improve walking function in stroke survivors by altering gait asymmetry. The study, published in IEEE Transactions on Neural Systems and Rehabilitation Engineering, reveals that the exoskeleton can effectively train individuals to modify their walking asymmetry.
Hourly heat exposure and acute ischemic stroke
A study of 82,000 patients found a strong association between hourly heat exposure and the onset of acute ischemic stroke. The findings suggest that high ambient temperatures may contribute to an increased risk of cerebrovascular events under global warming.