Articles tagged with Cerebrovascular Disorders
Jeffrey W. Moses, MD, is recognized for advancing the field of interventional cardiovascular medicine through technical excellence and leadership. Dr. Moses has performed over 20,000 interventional procedures and made significant contributions to clinical research and educational activities in interventional vascular therapy.
A groundbreaking study found that areas of age-related damage in the brain relate to motor outcomes after a stroke, suggesting other factors are at play. White matter hyperintensities were associated with more severe motor impairment, independent of corticospinal tract damage.
Researchers at UCLA Health have developed a potential biomarker for stroke risk using a network of inflammatory molecules in the blood. The study, published in the journal Stroke, found that patients with higher concentrations of these molecules had an 84% chance of experiencing a stroke during their lifetime.
A portable robotic device has been developed to improve walking function in stroke survivors by altering gait asymmetry. The study, published in IEEE Transactions on Neural Systems and Rehabilitation Engineering, reveals that the exoskeleton can effectively train individuals to modify their walking asymmetry.
A study of 82,000 patients found a strong association between hourly heat exposure and the onset of acute ischemic stroke. The findings suggest that high ambient temperatures may contribute to an increased risk of cerebrovascular events under global warming.
A new study found that chronic exposure to PM2.5 is associated with increased risk of hospital admission for various cardiovascular conditions, particularly ischemic heart disease and cerebrovascular disease. The study suggests that lowering annual average PM2.5 levels could decrease overall cardiovascular hospitalizations by 15%.
A new study from the University of Toronto found that older Canadians with a history of stroke experienced depression during the COVID-19 pandemic. Among those with no lifetime history of depression, immigrant status and family stressors were associated with an increased risk of incident depression.
A new study found that women with migraines and long-term hot flashes or night sweats are at increased risk of heart disease and stroke. However, the research suggests that focusing on prevention and correcting unhealthy habits can help most women mitigate this risk. Women who have experienced both migraines and vasomotor symptoms for ...
Earlier anticoagulation reversal is associated with improved outcomes after intracerebral hemorrhage, supporting efforts to accelerate evaluation and treatment. This study supports intensive care strategies to improve survival rates among patients with this devastating form of stroke.
A randomized clinical trial of 1,680 patients with acute ischemic stroke due to large-vessel occlusion found no significant improvement in disability with adjunctive methylprednisolone. The study suggests that methylprednisolone may not be effective as an adjunct therapy after endovascular thrombectomy for this patient population.
A study of 352 patients found that endovascular thrombectomy benefits both directly presenting and transferred patients with large ischemic strokes, with better functional outcomes observed in those presenting directly to EVT-capable centers. Prolonged transfers worsened outcomes due to evolving ischemic change.
Intravenous thrombolysis (IVT) plus thrombectomy demonstrates significant benefits over thrombectomy alone when administered within a short timeframe after symptom onset. This study, based on individual participant data from six randomized clinical trials, found IVT before thrombectomy to be time-dependent and statistically significant.
A Kessler Foundation study found that spatial neglect affects a substantial percentage of people with traumatic brain injury, with an incidence rate of 38% post-TBI. The study also revealed that right brain damage is more likely to result in spatial neglect, highlighting the need for timely treatment and screening guidelines.
Researchers found that whole-word errors are influenced by egocentric position, while unilateral paralexias are not. A failure of selective attention also contributes to whole-word intrusion errors. The findings suggest different rehabilitative approaches are needed for each type of error.
Earlier onset of atrial fibrillation is associated with an elevated risk of subsequent all-cause dementia, Alzheimer's disease, and vascular dementia. Monitoring cognitive function among patients with atrial fibrillation, especially those younger than 65 years at diagnosis, is crucial.
A national study of approximately 3,500 women found that those with a history of stroke are more likely to believe they won't receive adequate emergency care due to their gender and race. This perception may lead to delays in treatment for stroke patients, highlighting the need for improved healthcare equity.
Researchers have successfully tested an MRI-equipped ambulance, enabling faster diagnosis of stroke patients and streamlining care. The device can provide diagnostic-quality images without radiation exposure, improving treatment outcomes.
Researchers discovered a non-invasive eye exam that can detect early signs of cognitive decline and cerebral small vessel disease, a major contributor to vascular dementia. The study found connections between altered retinal blood flow and changes in brain structure associated with the condition.
A meta-analysis found that CPAP treatment adherence is associated with a lower risk of recurrent cardiovascular events in patients with obstructive sleep apnea. Adherence to CPAP therapy may be a key factor in secondary cardiovascular prevention.
A study of nearly 10,000 subarachnoid hemorrhage cases in Finland found significant variations in mortality rates among university hospital districts. Patients treated at Helsinki University Hospital and Oulu University Hospital had the lowest mortality rates, with a difference of 52% compared to Turku University Hospital.
Researchers tracked over 25,000 people using wearables data and found that daily living activities of at least moderate intensity can reduce major cardiac events; longer bouts lasting 5-10 minutes may have comparable health benefits.
A research team from USC Keck School of Medicine has developed a more rigorous system for conducting preclinical research on stroke treatments, identifying the strongest candidate for further study. The system uses a network of laboratories and animal models that resemble typical stroke patients to test new therapies.
The Stevens INI is expanding its health disparities research with a new award to examine vascular causes of dementia in Asian Americans. The project aims to use innovative imaging techniques and clinical translations to better understand cerebral small vessel disease (CSVD) and its impact on cognitive impairment and dementia.
Research suggests that certain gut problems, such as gastroparesis, dysphagia, and irritable bowel syndrome (IBS), may precede the development of Parkinson's disease. A nationwide medical record network study found a significant association between these conditions and an increased risk of Parkinson's diagnosis.
Research reveals that high blood pressure disrupts artery cell messaging, causing arteries to remain constricted and limiting blood flow to the brain. The study provides a potential route for developing first-ever drug treatments for vascular dementia.
Researchers found that adults who experienced violence, financial stress, or separation from parents as children were more likely to experience physical and cognitive impairments. Adverse childhood experiences can have lifelong consequences, including difficulty walking, carrying out daily activities, and problems with memory.
A new combination treatment for brain hemorrhage significantly improves survival rates and reduces disability. The INTERACT3 study shows a Care Bundle of readily available treatments can improve outcomes, particularly in low- and middle-income countries where most cases occur.
Hospitals affected by ransomware may see increased patient loads and resource strain, impacting time-sensitive care for acute stroke patients. Targeted cyberattacks can have regional disaster implications on healthcare delivery.
A team of clinicians successfully treated an aggressive vascular malformation in an infant's brain before birth, preventing potentially fatal symptoms and brain damage. The procedure marked a paradigm shift in managing vein of Galen malformation, reducing the risk of long-term disability or death.
A new study published in Neurology shows that younger brain age is associated with superior post-stroke outcomes, suggesting a potential biomarker for stroke rehabilitation. The research team used multi-site data sets and 3D brain structural MRIs to analyze the relationship between brain age and stroke recovery.
A new cell therapy has demonstrated significant benefits in improving the heart's pumping ability and reducing the risk of cardiovascular death, heart attack, or stroke in patients with chronic heart failure. The therapy, using mesenchymal precursor cells (MPCs), also showed a strong signal in reducing inflammation and improving microv...
A new study by the Cleveland Clinic found that high levels of erythritol, a popular artificial sweetener, are associated with an increased risk of heart attack and stroke. Researchers studied over 4,000 people and found those with higher blood erythritol levels were at elevated risk of experiencing a major adverse cardiac event.
A new study found that stroke patients experience a daily rhythm in cerebral blood flow regulation, with greater regulation during afternoon hours compared to morning and night times. This discovery may improve health outcomes by guiding daily activity and personal care during stroke recovery.
A new study from Duke University found that a person's race affects their inclination to ask questions, with Black women asking half as many questions as White participants. This may impact diagnosis and treatment of communication impairments resulting from right hemisphere stroke.
Researchers from Kessler Foundation are enrolling participants in a national trial testing a breakthrough device for improving recovery after stroke. The EMAGINE Stroke Recovery Trial pairs therapeutic exercise with electromagnetic stimulation to enhance brain and spinal cord function.
A new study found racial and ethnic disparities in brain aging among middle-age and older adults. In late life, Latinx and white adults experienced more pronounced brain aging, while Black adults showed accelerated brain aging in midlife.
A large stroke trial found that intensive blood pressure lowering after clot removal compromises the return of blood flow to the affected area, leading to more brain tissue deterioration and major disability. The study suggests that this increasingly common treatment strategy should be avoided in clinical practice.
A large UK Biobank study found that COVID-19 infection is associated with a heightened risk of poor cardiovascular health and death, particularly among those who require hospital admission. The risk remains elevated for some time after the initial infection.
A study found that increased prism adaptation treatment sessions improve spatial neglect symptoms, while more frequent sessions lead to greater rehabilitation gains. The authors recommend starting PAT early for optimal dosing.
A national study by UC San Francisco found that basic home blood pressure cuffs and smartphone-connected devices have no significant difference in improving blood pressure control. After six months, patients who used basic cuffs had a lower blood pressure reduction compared to those using Bluetooth-enabled devices.
Researchers tested a core-strengthening program using the AllCore360º to improve trunk function, balance, and mobility after stroke. The study showed promising effects on functional outcomes, including improved lateral control of posture and standardized treatment dosage.
Residents in predominantly Black communities are more likely to live near a hospital with a certified stroke center but face lower chances of receiving optimal treatment. The study also reveals significant disparities in access to stroke centers based on income and geographic location.
Researchers found a potential association between COVID-19 vaccines and an increased risk of coagulation disorders and coronary artery disease events. The study analyzed data from Norway, Finland, and Denmark to investigate this connection.
Researchers at the University of Strathclyde recommend delaying clinical trials for gel-based treatments for stroke due to current limitations. The study highlights gaps in knowledge regarding interactions with human stroke tissue and scaling up gel volume.
A study by researchers at UCSF found that e-cigarette use costs the US $15 billion annually in healthcare expenditures, with each user paying around $2,000 extra per year compared to non-users. The study, published in Tobacco Control, highlights the growing concern over health care costs associated with e-cigarette use.
A modified cardiac rehabilitation program has been shown to reduce mortality rates among stroke survivors by 76%. The program, which includes medically supervised exercise and therapy, improves functional capacity, mobility, self-care, and cognition. This finding has the potential to change the future of stroke care.
New research reveals that women with strokes often exhibit generalized symptoms such as confusion and weakness, potentially leading to delayed diagnoses. Women also face worse post-stroke outcomes, including increased institutionalization rates, compared to men.
A new analysis reveals that salt substitutes are not only effective in reducing stroke risk but also cost-saving, with costs outweighing the cost of the intervention. The study found a 14% reduction in stroke risk and 13% reduction in strokes and heart attacks combined.
Researchers developed a user-centered virtual reality system to engage stroke survivors with spatial neglect in intensive therapy, showing promising results. The system uses head-mounted displays and hand-tracking technology to deliver standardized treatment in an engaging environment.
A new study published in the Journal of the American Geriatrics Society found that more intensive hypertension treatment can delay or prevent strokes in older adults. The analysis of nine clinical trials involving 38,779 adults aged 66-84 showed a significant reduction in stroke risk with more aggressive treatment.
Researchers analyzed fMRI studies on healthy individuals and stroke survivors to understand the neural mechanisms underlying prism adaptation therapy. The study found differences in brain activity patterns between healthy individuals and those with spatial neglect, suggesting a shift in spatial processing to the left hemisphere.
Researchers at University of California San Francisco have catalogued over 40 previously unknown cell types in the human brain's blood vessels. These findings connect hemorrhagic stroke with novel immune cells, offering new targets for therapies.
A new study by the University of California - San Francisco found an association between increased drinking and hospital visits for atrial fibrillation in a large population. The study linked acute alcohol consumption with a higher risk of new-onset AF in previously undiagnosed individuals.
Researchers found that delirium and spatial neglect are associated with widespread dysfunction of brain networks, including arousal, attention, and spatial orientation. This imbalance may contribute to chronic cognitive decline after stroke.
A new contrast agent has been developed to detect and image blood clots noninvasively, using a targeted approach to find clots anywhere in the body. The agent was tested in patients with atrial fibrillation and showed promising results.
Researchers identify key neurons and signaling pathway regulating female activity before ovulation. Discoveries could lead to new treatments for menopause that sidestep estrogen and reactivates the circuit with CRISPRa technology.
A systematic review found spatial neglect to be prevalent among 29% of unilateral stroke survivors, with higher rates in right brain strokes and ecological assessments. This condition impairs cognitive and motor functions, slowing rehabilitation progress and increasing risk for injury.
The CAPTIVA trial will enroll 1,683 patients with symptomatic intracranial arterial stenosis and determine if two new prospective therapies are more effective than aspirin plus clopidogrel at reducing the risk of a second stroke. Intensive medical management and lifestyle modifications will also be provided to all patients.
A new study by the University of California, San Francisco found that consuming even one alcoholic drink can significantly increase the risk of atrial fibrillation. The research involved tracking 100 patients with documented AF and found that those who consumed more alcohol had higher odds of experiencing an AF episode.
Researchers found that a mobile interventional stroke team treated patients faster and with better outcomes than standard care. Patients treated by the MIST team were more likely to be functionally independent at 90 days post-stroke.