A study from the University of Notre Dame found that over 100,000 people were infected with COVID-19 by early March, despite only 1,514 reported cases and 39 deaths. The researchers attribute this to limited testing and gaps in surveillance during the initial phase of the epidemic.
A recent study published in the Journal of Infectious Diseases found that stay-at-home orders significantly slowed the spread of COVID-19 in the United States. The study analyzed data from 45 states with stay-at-home orders and found an average doubling time increase of 12.27 days, indicating significant slowing of disease spread.
A new study published in PLOS Medicine found that government-implemented physical distancing measures significantly slowed the spread of COVID-19 in the US. The study analyzed data from the first five months of the epidemic and found that average daily case growth rates declined after implementation, and that the number of cases double...
A multidisciplinary team from UTMB discovered a Zika virus mutation that may have contributed to the 2015/2016 epidemic and microcephaly cases. The study found that this mutation enhances mother-to-baby transmission, neurological disease, and lethality in newborn mice.
The special collection highlights RWHAP's strategies for improving HIV care, including pre-exposure prophylaxis (PrEP), data analysis, and collaborative efforts. HRSA's program serves over half a million people in the US annually, achieving high viral suppression rates.
Historical modelling analysis suggests that community-led interventions, including public hygiene initiatives and social distancing measures, played a crucial role in controlling the Typhus epidemic in the Warsaw Ghetto. The study highlights the importance of grassroots efforts in combating infectious diseases.
Research shows a correlation between epidemics in humans and local biodiversity loss, with the number of epidemics increasing as endangered species disappear. Livestock expansion worldwide exacerbates this risk, facilitating the transmission of pathogens.
Scientists charted SARS-CoV-2 transmission in Brazil, revealing that non-pharmaceutical interventions were insufficient to control the spread. The study found over 100 internationally-sourced virus introductions from Europe and estimates that more than 75% of Brazilian strains fell under three clades introduced during a specific period.
Scientists from CNRS and University of Nantes have developed a mathematical model to predict the risk of epidemic emergence based on seasonal factors. The 'winter is coming' effect suggests that pathogens introduced before unfavorable winter periods are less likely to cause large epidemics.
A new study published in PLOS Medicine suggests that combining self-imposed prevention measures like handwashing and mask-wearing with government-imposed social distancing can delay and reduce the peak of a COVID-19 epidemic. The model found that if self-imposed measures exceed 50% efficacy, large epidemics can be prevented.
A simple measuring tape could identify which Zika virus-exposed children develop neurological abnormalities. Head circumference growth trajectory is also key, with 10.5% going on to develop microcephaly in months after birth.
A scalable connectivity-aware solution is being developed by George Mason University researcher Sai Manoj Pudukotai Dinakarrao to confine the spread of COVID-19 and future epidemics. The solution aims to address epidemic model uncertainties and provide a cognitive approach for diverse demographics.
A new study found that regions with early interest in face masks had milder COVID-19 epidemics, with correlations seen in Asian countries such as Hong Kong and Taiwan. The use of face masks was linked to lower infection rates, suggesting its potential role in slowing the spread of the virus.
A new modeling study evaluates COVID-19 epidemics in lower-income countries and finds that even with reduced risk due to younger populations, limited healthcare capacity and inter-generational contact increase overall risk. Mitigation strategies are crucial to prevent health system overburdening.
Researchers surveyed commercial and residential citrus trees in Texas from 2007 to 2017, finding that the proportion of infected trees and psyllids increased exponentially over time. The study suggests that a flatter progression of citrus greening disease epidemics could be achieved through targeted protection and management strategies.
A new partnering agreement will finance a multi-centre Phase 2/3 adaptive clinical trial in Colombia, Panama, and Thailand to assess the safety and immunogenicity of the BBV87 vaccine candidate. The investment aims to accelerate the development of an effective Chikungunya vaccine for equitable access.
A Canadian study of global COVID-19 data found that temperature and latitude are not associated with the virus's spread, contrary to initial expectations. However, school closures, social distancing, and other public health measures have been shown to slow epidemic growth.
A new study published in Frontiers in Medicine found that early government intervention was crucial in limiting the spread of COVID-19 cases in Hunan province, China. The research team used a modified SIR model to compare infection trends between Hunan and Italy, finding that early measures reduced infection rates by up to 70%.
A commentary warns of a potential suicide epidemic in the US due to the COVID-19 pandemic, as gun sales skyrocket and social distancing disrupts support networks. The authors discuss ways to address this growing concern and mitigate its impact on public health.
Global experts call for international assistance as African nations battle COVID-19 and HIV. The authors argue that success in one country is limited if epidemics continue elsewhere.
Italian researchers used a spatial model to analyze the impact of mobility restrictions on COVID-19 transmission. The study found that restrictive measures reduced hospitalizations by 45% and avoided 200,000 cases.
The study highlights the disproportionate impact of COVID-19 on displaced populations, who are often stigmatized and blamed for disease spread. The authors share lessons learned from past epidemics to inform a more effective, inclusive COVID-19 response.
A new modelling paper from Ontario indicates that dynamic physical distancing measures can reduce COVID-19 transmission while providing periodic psychological and economic relief. The study shows that modulating response measures can prevent ICU overloads without overwhelming the healthcare system.
A modelling study suggests that relaxing control measures in regions outside Hubei province could lead to a second wave of COVID-19 infection, with cases potentially exceeding 1 and resulting in higher health and economic loss. The study advises policymakers to fine-tune control measures using real-time monitoring of transmissibility a...
A new mathematical model, developed by researchers at Carnegie Mellon University and Princeton University, uses information theory to improve epidemiological predictions. The model takes into account the evolutionary changes of both disease and information, allowing for more accurate predictions of epidemic spread.
Researchers analyzed China's control measures during the first 50 days of the COVID-19 epidemic and found that they may have prevented over 700,000 infections outside of Wuhan. The study suggests that these measures successfully broke the chain of transmission by preventing contact between infectious and susceptible people.
A modified Grunow-Finke assessment tool (mGFT) has been validated against previous outbreaks, outlining 11 criteria for determining if an outbreak is of unnatural origin. The tool helps identify unusual strain patterns, genetic manipulation, and peculiar geographic distribution, indicating potential artificial origin.
A new mathematical model developed by Princeton and Carnegie Mellon researchers improves epidemic tracking by accounting for disease mutations. The model provides critical insights into the effects of countermeasures, such as quarantines, on epidemic spread.
A global consortium of researchers found that travel restrictions were most useful during the initial phase of the COVID-19 outbreak and again as local transmission became established. Provinces that acted early to contain imported cases fared best in preventing outbreaks.
The article highlights the potential for COVID-19 to evolve into a chronic condition similar to influenza, with links to cardiovascular disease. Researchers warn of the risk of reemergence or emergence of other coronaviruses due to genetic recombination.
Researchers estimate that extending school and workplace closures in Wuhan until April would delay a second wave of cases until later in the year, relieving pressure on health services. Physical distancing measures are likely to be most effective if staggered return to work commences at the beginning of April.
Researchers found that white men between 30 and 39 are most at risk of fatal overdoses, followed by black men ages 30 to 39. The study identified 12 clusters or hot zones across Ohio where opiate-related mortalities are highest.
Researchers analyzed public genome sequence data to determine the origins of SARS-CoV-2. They found no evidence that the virus was engineered or created in a laboratory, supporting natural evolution as its origin.
A new study found that news exposure closely linked with public attention to Zika in the US during the 2016 outbreak. The analysis showed synchronized patterns of Wikipedia page views with mentions of the virus in web and national TV news.
A Brazilian study found that consuming contaminated water with saxitoxin worsens Zika neurotoxicity, tripling cell mortality and causing microcephaly-like malformations. This research highlights the public health problem of low water quality in the Northeast region, exacerbating the effects of arbovirus diseases.
Researchers stress that individual actions, such as self-isolation and social distancing, are key in controlling the pandemic. Governments can also take measures like banning large events and ensuring healthcare provision, but these must be balanced with economic considerations.
Researchers from Rice University and the University of Michigan created a model to predict the severity of multipathogen epidemics based on within-host pathogen interactions. The study used zooplankton as a model organism and found that altering the order of infection can change the course of an epidemic.
Researchers at the University of São Paulo, Adolfo Lutz Institute, and Oxford University have published the complete genome sequence of SARS-CoV-2 in Brazil. The study reveals differences between the genomes of viruses isolated from two Brazilian patients, suggesting internal transmission is occurring in European countries.
Researchers at Carnegie Mellon University developed a mathematical theory that takes into account evolutionary changes in pathogens or information. This theory was tested against thousands of computer-simulated epidemics and found to be more accurate than traditional models.
A Dartmouth-led study found that counteracting myths about Zika in Brazil actually reduced the accuracy of people's other beliefs about the disease. Information intended to correct misperceptions may have unintended effects on public health campaigns.
A study found that volunteer-based outreach programs, such as door-to-door canvassing in Liberia, can effectively spread valuable information and change public practices during epidemics. The program improved health outcomes, increased public trust in government institutions, and led to more people following control measures.
New research reveals that opioid-related deaths may be 28% higher than reported due to incomplete death records. The study found that almost 72% of unclassified drug overdoses involved prescription opioids, heroin, or fentanyl.
African countries with strong preparedness and detection capabilities are better equipped to handle a potential outbreak, while those with lower scores face significant risks of nondetection and local spread.
A Zika virus strain in northeastern Brazil was particularly damaging to the developing brain, causing microcephaly in over 80% of cases. Researchers found that this strain led to neurodegeneration and smaller brains, but other factors such as environmental viruses may have also played a role.
Researchers at Umeå University reviewed 12 studies on coronavirus transmissibility, finding it to be significantly higher than WHO estimates. The reproduction number calculated from these studies ranges from 2.79 to 3.28, indicating a high risk of rapid spread.
Scientists have developed a new model to predict the speed of epidemics in networks, providing insights into the trajectory and rate of global spread. The analysis assesses each node's likelihood of infection by a certain time, enabling more accurate forecasting of epidemic dynamics.
A new modelling study estimates that up to 75,800 individuals in Wuhan may have been infected with 2019-nCoV by January 25, 2020. The researchers also suggest that multiple major Chinese cities might have already imported dozens of cases of 2019-nCoV infection from Wuhan.
Researchers at the University of Rochester found that parents' consistent bedtime enforcement is associated with longer sleep duration and better mental health outcomes for teenagers. The study suggests that even without pre-bedtime conflict, parents' role in setting bedtimes yields positive results.
A nationwide nicotine vaping prevention program, CATCH My Breath, will be assessed for its effectiveness in delaying e-cigarette use among sixth to eighth grade students. The study aims to address the growing youth vaping epidemic and its long-term health hazards.
A commentary published in the American Journal of Public Health argues that existing metrics are insufficient to track the public health response to HIV in the US. Newer metrics are needed to inform and evaluate efforts aimed at reducing new HIV infections by 75% and 90% over the next five and ten years, respectively.
A study by Princeton University researchers found that climate change could lead to more frequent and earlier outbreaks of RSV respiratory infection in North America. The virus' spread is influenced by humidity and rainfall, which are expected to shift northward due to changing weather patterns.
Researchers highlight the need to address comorbidities such as heart disease, kidney disease, and certain cancers associated with HIV. Effective treatment strategies and clinical trials are crucial to reducing the burden of these conditions on individuals and the healthcare system.
The US is experiencing several simultaneous opioid epidemics, including prescription drug, heroin, synthetic opioids, and a syndemic in counties where the crisis first erupted. These distinct challenges require varied policy responses.
A study from the University of Georgia found that over 90% of opioid-related hospitalizations are among patients with two or more chronic diseases, highlighting the association between chronic disease and opioid misuse. Researchers argue that prioritizing chronic disease prevention could alleviate the opioid epidemic.
Scientists developed a new simulation tool to analyze the spread of disease in seed systems, identifying key villages for surveillance and management. This approach can be applied to other plant diseases, such as cassava mosaic disease in Southeast Asia.
A team of researchers from EPFL and MIT used mobile phone location data to study the spread of dengue fever in Singapore. Their findings showed that even low levels of mobility can cause an epidemic to spread, emphasizing the need for effective spatial distribution models.
A team of scientists has developed new ways to forecast dengue infections by combining disease and climate data. The project aimed to predict maximum weekly cases, the week of peak cases, and total season cases, but models still struggle to accurately predict epidemics.
The study assesses the performance of dengue forecasting models across 8 seasons in Peru and Puerto Rico, revealing improved accuracy late in the season. The results provide a framework for refining future epidemic forecasting models, improving predictive skill over time.
A new study from the University of Pennsylvania School of Nursing used a mystery shopper methodology to evaluate the quality of HIV/STI testing services for young men who have sex with men. The results showed variable performance across cities and testing sites, emphasizing the need to improve these services.
Researchers used drone and satellite imagery to map snail habitats in the Lower Senegal River Basin, finding that non-emergent vegetation was a stronger predictor of human infection than host snail counts. Removing this vegetation may benefit snail control efforts, reducing schistosomiasis transmission risk near human water-contact sites.