Researchers have pinpointed a single genetic code variation in African Salmonella that enables its virulence, contributing to devastating bloodstream infections. The discovery has implications for understanding and combating this dangerous strain of bacteria.
A study by the University of Waterloo found that early childhood behaviors are strong predictors of adult obesity. The research team identified four clusters of risk: Inactive Screen-Users, Moderately Active Substance Users, and two groups with healthier behaviors. Public health efforts should focus on modifying these behaviors earlier...
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African Salmonella's deadly epidemic is caused by a specific genetic change, known as a SNP, which helps the bacteria survive in the human bloodstream. The discovery could lead to new insights into other pathogens and pave the way for a vaccine against this devastating infection.
A new study found that Rhode Island's opioid addiction treatment program for inmates reduced post-incarceration drug overdose deaths by 61% and contributed to an overall 12% reduction in overdose deaths statewide. The program provides medications for addiction treatment (MAT) for those who need it, with linkage to community treatment a...
A randomized controlled trial found no significant difference in weight status among children taking part in a school-based lifestyle and healthy eating program compared to those not participating. The study suggests that wider influences from families, communities, and the food industry may have a greater impact on childhood obesity t...
Researchers analyzed daily social encounters of 1,450 residents to better understand epidemic growth. They found that age and day-to-day variation play a significant role in shaping these patterns.
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Research classifies olive varieties by their susceptibility to anthracnose, with Picual variety found to be highly resistant. Almost all Spanish cultivars are classified as susceptible or moderately susceptible, highlighting the need for farmers to choose resistant varieties.
A recent study published in Nature Scientific Reports suggests that containment measures during epidemics can make a society less resilient and more vulnerable to economic and social disruption. By limiting mobility, authorities may create greater risks than they mitigate. The study's findings highlight the need for policymakers to con...
Researchers developed a new theory identifying key individuals spreading news and viruses in epidemics by analyzing message transmission dynamics. The study predicts the influence of spreaders in networks, enabling efficient immunization strategies and identifying influential actors.
The Colorado Consortium for Prescription Drug Abuse Prevention at CU Anschutz Medical Campus receives a $1.5 million grant from the Colorado Health Foundation to advance its mission to reduce misuse and abuse of prescription drugs in Colorado.
Researchers design a mathematical model that predicts how mobility affects disease spread, finding that daily mobility reduces epidemics in large cities. The model suggests that recurring mobility helps even out population density, reducing the occurrence of epidemics.
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Conflict-induced displacement of people in eastern Ukraine has been shown to drive the spread of HIV within the country. The largest exporters of viral lineages were regions of Donetsk and Lugansk, which then spread to central and southern regions, as well as cities like Kyiv and Odessa.
Researchers from Max Planck Institute and Harvard University use ancient DNA analysis to uncover the possible cause of a devastating epidemic in Oaxaca, Mexico. The study found evidence of Salmonella enterica Paratyphi C, a pathogen that causes enteric fever, in skeletons of victims of the cocoliztli epidemic.
A commentary argues that Canada should develop a regulated program to distribute pharmaceutical-grade opioids to people at highest risk of overdose. This approach aims to provide safer alternatives to illegal sources of pain relief, reducing the protracted epidemic of overdose deaths.
A recent spike in homicide rates across the nation doesn't tell the whole story. According to a new UT Dallas study, long-term factors like segregation and poverty play a more significant role in increases than short-term fluctuations. The study found that most cities' homicide rates have remained relatively stable over time.
Researchers found that women are more likely to survive crises like famines and epidemics due to biological factors, not behavioral differences. Newborn girls are particularly hardy, outliving newborn boys by up to 50%.
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Building stronger health systems in Madagascar could significantly reduce plague outbreak severity, as recent epidemics have shown. Improvements include staffing, infrastructure, supply chain enhancements and surveillance data integration.
Experts argue that sugar may play a key role in obesity and type 2 diabetes due to its unique metabolic effects, potentially beyond just excess calories. The World Health Organization describes the twin epidemics as a 'slow-motion disaster,' but critics say current recommendations targeting only calories are insufficient.
Researchers found that dietary trehalose enhances the virulence of epidemic C. difficile lineages, leading to increased disease severity and mortality in animal models. The study suggests that trehalose may be a key trigger for the predominance of these lineages, contributing to hospital-acquired infections.
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A recent study by Hokkaido University found that the global risk of Madagascar's pneumonic plague epidemic is limited, with an estimated risk of less than 0.1 person per country between August and October. The basic reproduction number was calculated at 1.73, and case fatality risk was 5.5 percent.
A new study found that heavy rainfall can indicate upcoming outbreaks of mosquito-borne viruses Zika and Chikungunya. The researchers developed a framework to predict where and when future outbreaks will occur, enabling municipalities to prepare measures to limit the spread of diseases.
A new model reveals that cooperative contagion processes can lead to more severe spread of infectious diseases, generating abrupt outbreak transitions and multi-stability. This discovery highlights the need for new containment strategies to combat epidemics in realistic systems.
Researchers are developing abuse-deterrent opioids with special coatings or infusions to make them harder to misuse, but at a higher cost. Novel painkillers and powerful opioid detectors are also being developed to help combat the crisis.
Researchers analyzed genomic data to identify the source of the seventh cholera pandemic, linking it to human-related transmission factors. The study found that the pandemic strain was introduced into Africa at least 11 times since 1970, replacing drug-susceptible populations with multidrug-resistant bacterial sublineages.
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Researchers developed a new 'rule-book' to estimate the risk of different cholera strains causing epidemics. The study found that 7PET strains from Asia repeatedly introduced into two main regions of Africa: West Africa and East/Southern Africa, leading to massive epidemics in some cases.
A study by UTHealth researchers found that a 'promiscuous' carbapenemase gene and a bacterial clone carrying an antibiotic-killing gene created the perfect storm for Colombia's antibiotic resistance epidemic. The gene spread horizontally across Gram-negative bacteria, while the clone was introduced via an infected patient from the US.
A study reconstructing climatic patterns in China from AD 1-1911 found long periods of cold and dry conditions associated with epidemic outbreaks. However, the relationship between temperature and epidemics varied across short time scales, highlighting climate's scale-dependent impacts on disease prevalence.
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Gun violence in US cities like Washington D.C. shows an endemic pattern, with clustering in certain neighborhoods rather than spreading rapidly. Researchers recommend place-based interventions targeting neighborhood features to reduce crime rates.
A 12-week course of hepatitis C drugs can be manufactured for just $50, making it cheaper than a plane ticket on many low-cost airlines. Generic copies are as effective as branded medicines, but restrictions and patent issues prevent widespread access.
African teams join forces with UK experts to develop novel treatments for malaria and sleeping sickness, as part of the £7 million Tackling Infections to Benefit Africa (Tiba) project. The initiative aims to strengthen health systems across the continent.
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A new study assesses pandemic potential in Africa prior to outbreaks, mapping vulnerabilities to mitigate the spread of Ebola and other deadly viruses. Researchers identify high-risk locations, including parts of Central African Republic, Chad, Somalia, and South Sudan, highlighting the need for targeted preparedness activities.
Researchers analyzed data from thousands of students and found a significant decline in narcissism, particularly in traits like vanity and entitlement. The average college student scores lower on the Narcissism Personality Inventory than grandparent counterparts, suggesting that age brings a decrease in narcissistic tendencies.
A study suggests that donor organs classified as 'increased risk' due to factors like drug use or incarceration are less likely to be used by transplant patients. Despite low disease transmission risks, these organs account for 1 in every 5 deceased donor organs and could lead to hundreds of additional transplants each year.
Researchers identified a single genetic change, S139N, that enabled the Zika virus to cause microcephaly in mouse models of fetal infection. This mutation made the virus more lethal to human neuron precursor cells and substantially more severe in cases of microcephaly.
A study by Northeastern University expert Marco Ajelli found that people who spend less time outdoors are less likely to contract the Zika virus. However, a small group of people who spend large amounts of time outdoors are at high risk for infection and can spread the disease quickly.
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Lesotho achieves high viral load suppression rates, while Uganda's previously expanding epidemic stabilizes due to circumcision and treatment expansions. New US strategy aims to accelerate progress in high-burden countries by 2020
A new report from The Lancet Commission highlights opportunities to improve health in Sub-Saharan Africa by seizing the workforce's growth and transforming health systems. The report emphasizes the need for prevention, public health, and primary care, as well as addressing emerging challenges like non-communicable diseases.
Conflict durations in monkey societies grow more quickly as others join, according to researchers studying dynamic conflict patterns. The first interaction sets the tone for the fight, with brief episodes likely to follow if initial interactions are brief.
Researchers found that changing routine boarding protocols could reduce the spread of disease on commercial airliners. A two-zone system where passengers board at random is suggested as a more efficient way to prevent infection.
The American Chemical Society has unveiled its annual 'Talented 12' list, showcasing young scientists working on world-changing projects. The researchers are developing alternative fuel sources, novel cancer treatments and innovative materials for everyday products.
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A team of scientists used whole genome sequencing to identify the cause of a respiratory disease that affected almost 77,000 native Icelandic horses in 2010. The researchers found that the gram-positive bacterium Streptococcus zooepidemicus was the culprit behind the outbreak.
Experts argue that working 24-hour shifts may not negatively impact patient care, but can lead to burnout. The medical profession must address the issue of sleep deprivation and its effects on doctors' wellbeing and patient safety.
The second Swaziland HIV Incidence Measurement Survey (SHIMS2) reveals significant progress in combating the HIV epidemic, with a doubling of population viral load suppression since 2011. The survey found nearly half fewer new HIV infections among adults aged 18-49 years compared to 2011.
A new study published in the International Journal of Epidemiology found that drug-related deaths have skyrocketed among middle-aged white men, increasing by over 25-fold between 1980 and 2014. The researchers argue that economic insecurities and an 'obesogenic' environment are contributing factors, rather than 'despair deaths'.
A recent study conducted in São Paulo, Brazil found that prior dengue infection does not intensify Zika disease severity. The research involved 65 individuals who contracted Zika virus during the 2016 epidemic, and analyzed their viral loads, finding no significant difference between those with prior dengue exposure and those without.
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Family physicians are well-qualified to treat addiction due to their focus on relationships, communities, and team-based care. Primary care physicians must be responsible for the initial and longitudinal care of patients with substance use disorders, and specialized services must be widely available and accessible.
A study published in The Lancet Diabetes & Endocrinology found that diabetes prevalence is increasing among low socio-economic backgrounds living in urban areas of affluent states in India. Diabete's rates are higher among people from low socio-economic status, especially in cities with poor access to healthcare.
Researchers analyzed 174 Zika virus genomes from patient and mosquito samples to reconstruct the virus's spread across South and Central America. The study suggests that Zika was circulating in Brazil around February 2014, months before local cases were detected.
Researchers used genome sequencing to track Zika virus spread across Brazil, discovering it was present a year before first confirmed cases. The study's findings have significant public health implications and could improve responses to future outbreaks.
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A study of schoolchildren found that overweight and obese kids drink more sugar sweetened soft drinks than their normal weight peers. The researchers suggest taxing such drinks could reduce consumption, particularly in children, and have the potential to impact the scale of childhood obesity.
Psychologist Robert Gatchel's research highlights how patients' irrational beliefs about chronic pain can impact treatment outcomes and pain management. His work suggests that a more comprehensive approach to treatment is needed, incorporating lifestyle habits, attitudes, and social support systems.
A new management approach developed by an international team of researchers, including the University of Warwick, helps to streamline outbreak decision-making. The approach identifies two effective strategies: reducing transmission rates at funerals and in communities, such as educating people about disease transmission.
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A new study models HIV incidence, prevalence, and mortality to determine feasible targets for ending the US AIDS epidemic. Achieving a reduction of 12,000 new infections by 2025 could mark an important turning point in the epidemic, with significant declines in HIV transmission rates and related deaths.
New research from Johns Hopkins Bloomberg School of Public Health reveals that the US could see a significant decline in HIV infections and prevalence if critical milestones are met. By 2025, annual new infections could drop to 12,000, marking a turning point for the epidemic.
A new USC-led study suggests that the prescription opioid epidemic is creating a heroin epidemic, which may lead to an injection drug use epidemic. The study found that individuals born in the 1980s and 1990s are more likely to progress from first illicit drug use to drug injection than previous generations.
A new computer model assesses real-time Zika epidemic risk in US cities by combining population dynamics, historical infection rates, socioeconomics, and mosquito density. The model predicts that certain counties in Texas have the highest risk of Zika transmission, while others have nearly no risk.
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A computational analysis led by Johns Hopkins Bloomberg School of Public Health researchers estimates that even a mild Zika outbreak in the US could result in $183 million in medical costs and productivity losses. A more severe outbreak could cost over $1 billion, with increased risks of birth defects and Guillain-Barré syndrome.
Hepatitis C patients with substance use disorders face barriers to care, including lack of access to conventional healthcare and fear of stigmatization. Innovative approaches, such as integrated screening and treatment in methadone clinics and telehealth techniques, are being developed to improve outcomes for this population
An international effort analyzed 1,610 Ebola virus genomes from the 2013-2016 West African epidemic, revealing insights into factors that sped or slowed the outbreak. The study found that cities played a major role in the magnitude of the epidemic and that distance between cities was key to sparing nearby regions from severe epidemics.
A point/counterpoint debate examines two approaches to controlling the opioid epidemic: increasing regulation of physician prescribing practices or better educating patients and doctors. The discussion highlights the importance of finding a balance between regulating opioid use and providing alternative pain management options.