A new method developed by Joana Goncalves-Sa's group can predict the onset of seasonal flu epidemics with accuracy, allowing health services to prepare and respond more promptly. The method integrates data from various sources, including official influenza incidence rates and Google searches, to identify changes in case numbers.
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Research suggests that cannabinoids in medical marijuana could alleviate heroin withdrawal symptoms and cravings. A specific compound, cannabidiol, shows promise in reducing anxiety related to cravings and restoring neurobiological damage.
A global partnership, CEPI, aims to create vaccines for emerging infectious diseases with a $460m initial investment from governments and foundations. The Coalition will target MERS-CoV, Lassa, and Nipah viruses, as well as Ebola and Zika, to develop safe and effective vaccines that can be deployed rapidly to contain outbreaks.
Research using 20,000 virus samples and weather statistics found that cold weeks precede flu outbreaks. Cold and dry weather allows aerosol particles to remain airborne, increasing the spread of viruses.
A study found that over half of Brazilian women aged 18-39 avoided pregnancy due to the Zika epidemic. The authors urge the government to review reproductive health policies and improve access to safe and effective contraceptives.
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A widely publicized initiative has placed over 95% of individuals with substance-use disorders into detoxification or treatment programs. The Gloucester Police Department's Angel Program has filled a needed gap in accessing substance-use treatment services, with 376 people seeking help in the first year.
Researchers developed algorithms to track Ebola epidemic spread, revealing that most infected individuals stayed within their districts. The study's findings suggest using this method could inform effective control measures for new emerging epidemics.
Researchers at the University of São Paulo developed a platform that analyzes clinical samples to diagnose infection by 416 viruses found in tropical regions. The tool is designed for reference laboratories and can detect pathogens with the potential to cause epidemics in humans.
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Researchers have found a strong association between El Niáo-Southern Oscillation conditions and observed weather in Sri Lanka, leading to exacerbated dengue epidemics. The study used the Oceanic Niño Index to quantify data associations and found an increasing relative risk of dengue with increasing rainfall and temperatures.
A Stanford-led study identified 14 individuals in Sierra Leone who had Ebola antibodies but no symptoms, contradicting previous assumptions about the disease's severity. The research suggests that 25% of Ebola infections were minimally symptomatic, and public health efforts may not have been effective in containing the virus.
A new study from Oxford University reveals that the first month after infection is crucial in controlling drug-related HIV spread. Researchers found that needle exchange programmes and harm reduction measures are essential in targeting transmissions within this period.
The use of prescription opioids in Canada has increased steadily over the past 20 years, leading to a rise in overdose deaths and addiction. Experts propose several interventions, including guidelines for prescribing, limited dosages, electronic monitoring systems, and access to evidence-based treatment.
Researchers discovered a non-virulent variant of Vibrio cholerae O1 strain in Haitian aquatic environments dating back to the 1500s, sparking concerns about its potential virulence through gene transfer with toxigenic strains. The study sheds light on the history of the pathogen and highlights the need for increased surveillance.
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The University of Pittsburgh Graduate School of Public Health recommends distributing naloxone to inmates upon release from jail and improving overdose data collection to combat the opioid epidemic. The policy focuses on vulnerable populations such as veterans, inmates, and school children.
Researchers reconstructed the origins of the AIDS pandemic in unprecedented detail by recovering genetic material from 40-year-old serum samples. The study suggests that HIV emerged in New York City around 1970 and spread rapidly across North America, with the city serving as a critical hub for the epidemic.
A new study proves that Gaétan Dugas was one of many thousands infected in the years before HIV was recognized. The term 'Patient Zero' was created inadvertently in the earliest years of investigating AIDS, and Dugas's global defamation is attributed to this mistake.
A recent survey of US adolescents found that most teens vape for flavorings rather than nicotine in e-cigarettes. The study suggests that efforts to curb vaping among teens focusing on nicotine may be ineffective and that alternative approaches may be more effective.
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Researchers cloned an epidemic strain of Zika virus, creating a model to test strategies for stopping the pandemic. The clone is used for developing a live but attenuated vaccine to create long-term immunity.
Researchers in Delaware are using geo-mapping to identify neighborhoods with high rates of fentanyl and opiate prescriptions, finding that women and people over 50 years old are prescribed these medications at higher rates than men. These 'hot spots' tend to be rural areas, suggesting a shift away from the urban drug problem narrative.
A new Brown University study projects that treating 2,000 Rhode Islanders for hepatitis C virus infection per year could reduce cases by 90 percent and prevent over 70 percent of expected liver-related deaths by 2030. The analysis found that doubling the number treated annually could reduce death rates by less than 20 percent.
A study published in PLOS Medicine found that maternal health services in rural Liberia suffered a significant impact during the Ebola epidemic, with facility-based deliveries decreasing by approximately 8%. The researchers noted that fear of transmission in health facilities was a major factor contributing to this decline.
A new study shows that substituting sick workers with healthy ones can explosively accelerate the spread of some epidemics, contradicting standard mass-action models. The researchers' dynamic network model indicates that a sudden reduction in replacement rates can lead to a significant increase in disease prevalence.
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The Ebola epidemic led to a significant decline in child and maternal health in Liberia, with a 30% reduction in facility-based deliveries. The study found that fear of Ebola transmission in healthcare facilities was the primary factor contributing to this decline.
Researchers propose that women in Zika-affected countries can safely conceive during the 'trough' of low mosquito activity, reducing the risk of birth defects. This approach could prevent thousands of cases per year, especially in Brazil and Puerto Rico.
The yellow fever virus, transmitted by Aedes aegypti mosquitoes, is a significant public health threat to the Americas. The recent resurgence of YFV in Africa and Asia, combined with vaccine shortages, highlights the need for urgent measures to prevent infection and control its spread.
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Researchers project up to 93 million people at risk of Zika infection, including 1.6 million childbearing women, due to herd immunity. The projections highlight the potential scale of the epidemic and emphasize the importance of addressing it before it spreads too far.
Researchers estimate that up to 90 million infections could result from the initial stages of the spread of Zika in Latin America and the Caribbean. The team's projections suggest Brazil is expected to have the largest total number of infections due to its size and suitability for transmission.
A recent model-based study suggests that the current Zika epidemic in Latin America will likely peak within three years, with subsequent herd immunity preventing future outbreaks. The authors also emphasize the importance of targeted mosquito control measures, which may actually hinder herd immunity.
A new study from Imperial College London predicts that the current Zika epidemic in Latin America will burn itself out within two to three years due to herd immunity. The team's analysis also concludes that large-scale transmission is unlikely to restart for at least another ten years.
A new study suggests that despite advances in HIV treatment, the epidemic continues among gay men globally due to inadequate access to preventive measures like PrEP. Stigma and discrimination also play a significant role in the spread of the disease.
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The 1976 Ebola outbreak highlighted the importance of rapid clinical recognition, international notification, and specimen provision. Researchers recommend strengthened preparation, detection, response, control mechanisms, and international cooperation to manage future outbreaks promptly.
Researchers found that microcephaly screening alone is insufficient to detect all cases of Zika virus in newborns. The study suggests that signs and symptoms of brain abnormalities should also be included in screening criteria.
Researchers found that Zika virus infection can persist for up to 70 days in pregnant monkeys, whereas non-pregnant animals clear the virus within 10 days. The study suggests that immune systems of mothers-to-be may be compromised, allowing the virus to linger.
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States with robust prescription drug monitoring programs saw a significant reduction in opioid-related overdose deaths, with an average of 1.55 fewer deaths per 100,000 population compared to states without such programs. Implementing these programs could prevent over 600 additional overdose deaths nationwide.
The prevalence of obesity in the US has increased among women, with a significant rise between 2005 and 2014, while rates for men have remained stable. Obesity affects over 38% of adults in the US, with class 3 obesity affecting around 7.7% of both sexes.
A new tool by Japanese researchers predicts the risk of Zika virus importation and local transmission for 189 countries, identifying subtropical and tropical nations as high-risk. Countries with a history of dengue and other mosquito-borne diseases face the greatest risk of infection.
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The WHO has convened an emergency committee due to the risk of a YF outbreak in unvaccinated populations in Asia. The World Health Organization is concerned about the limited supply of vaccine, but experts warn that this poses a strong risk of epidemics.
A global early warning system for infectious diseases is proposed to use computer models to forecast disease risk and inform targeted responses. This system could shift the paradigm from reactive to pre-emptive management of risk, minimizing damages and improving global health security.
A study published in Virus Evolution found that unconventional transmission routes like semen and breast milk contributed to the tail-end of the Ebola epidemic in Sierra Leone. The research used real-time sequencing of Ebola virus genomes to track the source of infection for some final cases.
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A global health emergency is looming due to the rapid spread and potential future outbreaks of yellow fever, say Georgetown University professors. The ongoing epidemic, particularly in Angola, has led to a significant shortage of vaccines and calls for an urgent international response.
Research suggests that climate change and resulting water shortages are linked to an increase in chronic kidney disease caused by dehydration and heat stress. The study found that rural hot communities are disproportionately affected, with risks increasing for cognitive dysfunction, malnutrition, and other conditions.
The 2013-2014 sea star wasting epidemic had a significant impact on the Oregon coast population, with up to 80% of sea stars dying during the outbreak. However, by spring 2015, the population was recovering in numbers, with study sites having up to 300 times as many new sea stars as in 2014.
The California sudden oak death epidemic cannot be stopped, but its impact can be reduced by starting control measures earlier. Mathematical modeling shows that targeting the 'wave-front' of the disease and 'front-loading' the budget are more effective methods of control.
A team of doctors analyzed brain scans of 23 babies born with microcephaly associated with Zika, revealing severe brain damage and abnormalities. The study found extremely severe brain calcification, malformations of cortical development, and delayed myelination in most cases.
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A warming climate is expanding Europe's seasonal window for mosquito-borne dengue fever, posing a significant global health concern. The study found that increased temperatures will intensify the ability of Aedes mosquitoes to transmit the disease, putting much of Europe at risk of seasonal outbreaks by the end of the century.
Researchers from the University of Cambridge found that diagnostic tests are crucial for forecasting major epidemics. The study shows that precise estimates of infected individuals cannot be inferred from data based on symptomatic cases alone, highlighting the need for reliable diagnostic tests to detect presymptomatic infections.
Researchers used cryo-electron microscopy to analyze the Zika virus strain isolated from an infected patient in French Polynesia. The analysis revealed that Zika's structure is similar to other flaviviruses, but with a slight difference in a region important for binding to antibodies and host receptors.
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Researchers found Mycoplasma pneumoniae infections in over half of hospitalized children with pneumonia in Beijing, predicting an ongoing epidemic. The study may help clinicians slow the spread of the disease.
Researchers propose a novel framework to uncover hidden patterns of transmission and identify super spreaders in epidemics. Asymptomatic carriers can play a significant role in spreading diseases, and understanding their contribution is crucial for targeted interventions.
A study by Georgia State University researchers found that healthcare providers' concerns about prescription drug abuse can lead to changes in prescribing and dispensing practices. The survey of nearly 6,000 health professionals revealed a majority were very concerned, but some dentists were relatively unconcerned.
A new policy report in Science issues recommendations for responding to infectious disease epidemics, citing the Ebola crisis as a framework. The report proposes rebuilding local health care infrastructures and improving international response capabilities.
A new analysis of deformed wing virus shows that the Varroa mite has spread globally due to human trade, contributing to an endemic to epidemic shift. The study provides insights into worldwide transmission routes and dynamics of DWV.
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Researchers at Institut Pasteur in French Guiana have sequenced the complete genome of the Zika virus, showing almost complete homology with strains responsible for the 2013-2014 Pacific epidemic. The analysis provides a major starting point for understanding how the virus behaves and shedding light on its impact.
A review analysis suggests that patient location and travel mapping limitations contributed to the Ebola epidemic's spread. Employing community members in mapping and education could have helped contain the outbreak.
A study develops new methods to detect the onset of critical transitions in infectious disease epidemics, such as malaria. The method identifies the critical slowing-down period in human cases, suggesting that eradicating the disease could be anticipated even without a full understanding of the underlying mechanisms.
A recent study by Dr. Anthony Griffiths reveals that the Ebola virus has a high frequency of spontaneous mutation, which could prove useful for developing therapies. Increasing the mutation rate may make the virus non-viable, providing a potential therapeutic tool against the disease.
A new mathematical model helps researchers predict the spread of dengue fever in urban areas by analyzing neighborhood conditions and human travel patterns. The SIR-Network model reveals that central neighborhoods are crucial hubs for transmission, emphasizing the need for countermeasures before epidemics peak.
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Researchers found that South Africa reduced childhood deaths associated with HIV but failed to meet the MDG4 goal due to its narrow definition. The country's progress is deemed a 'success' when considering overall child mortality levels, despite not meeting the target.
A York University study found that vaccination strategies should be adjusted based on region-specific characteristics, such as age demographics and virus transmission rates. Early vaccination leads to better public health outcomes, including reduced infection rates, hospitalizations, and stress on healthcare systems.
A novel statistical model mapped the spread of the 2014-2015 Ebola outbreak in Sierra Leone, providing the most detailed picture to date. The analysis suggests two critical opportunities to control the epidemic and identifies two critical points where intervention could have been more effective.
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