Articles tagged with Heart Disease
Researchers discovered that mitochondrial DNA (mtDNA) variants interact with nuclear DNA mutations to determine the severity of heart disease in mice. Different mtDNA variants conferred either worsened or protected heart damage, suggesting a key role for mtDNA in cardiomyopathy progression.
Researchers at Northwestern University developed a simple blood test called TimeSignature that can identify the body's precise internal time clock. The test measures gene expression markers and can be taken any time of day, allowing for more accurate diagnosis and treatment of diseases such as heart disease, diabetes, and Alzheimer's.
Scientists at Baker Heart and Diabetes Institute have identified plasma lipid biomarkers that improve upon traditional risk factors in predicting heart disease and stroke. The new blood test will use up to ten lipid markers to better diagnose heart disease, reclassifying patient risk and guiding treatment.
Researchers from the University of Bradford analyzed Anglo Saxon children's milk teeth to identify modern children at risk for conditions like diabetes and heart disease. The study found that teeth provide a more reliable indicator of diet and health than bones, revealing biomarkers for stress in early life.
Dr. Mandeep R. Mehra proposes a novel explanation for the Mona Lisa's smile and facial features, attributing them to clinical hypothyroidism. The theory is supported by visible signs of thyroid dysfunction in the painting, including thinning hair and yellow skin.
Researchers at MUSC and Ohio State University have discovered an unexpected mechanism that underlies cardiomyopathy in DMD. Inhibiting NF-κB normalizes calcium handling and significantly increases calcium gene expression, leading to improved heart function.
A new rapid imaging protocol has been developed and tested in Peru, quickly and cheaply diagnosing heart ailments in patients. The technique, which took 18 minutes and cost $150 per patient, revealed important changes in patient care and satisfied all imaging needs in 89% of patients.
A systematic review and meta-analysis found exposure to arsenic, lead, cadmium, and copper increases the risk of coronary heart disease and cardiovascular disease. The study suggests that even low doses of toxic chemicals pose a significant risk to cardiovascular health, highlighting the need for policymakers to take action to reduce p...
A comprehensive analysis of the evidence found exposure to toxic metals like arsenic, lead, copper, and cadmium to be associated with an increased risk of cardiovascular disease. The study suggests that these metals may be an independent risk factor for cardiovascular disease, even at relatively low levels of exposure.
A comprehensive analysis found associations between exposure to toxic metals and increased risk of cardiovascular disease and coronary heart disease. The study's authors call for attention to metals as a significant source of cardiovascular risk, highlighting the need for population-wide strategies to minimize exposure.
Research suggests that dairy products can protect against total mortality and cerebrovascular causes, but milk consumption increases the risk of CHD. Public health officials should revise guidelines on dairy consumption, recommending fat-free or low-fat milk.
A large study of Australian adults found that psychological distress was linked to a higher risk of heart attack and stroke. The researchers estimated that among women, high/very high psychological distress was associated with a 44 percent increased risk of stroke.
Researchers analyzed data from over 5,700 pregnant women with heart disease and found that fewer deaths occurred during pregnancy compared to previous years. However, nearly one in ten women with pulmonary arterial hypertension died during pregnancy or early post-partum. Pre-pregnancy counseling is crucial to identify high-risk patients.
A large study found that low-carbohydrate diets were associated with a 32% higher risk of all-cause death over an average 6.4-year follow-up. Risks were also increased for coronary heart disease, stroke, and cancer.
A large study found that care coordination strategies significantly reduce symptoms of depression and improve health in seniors with multiple chronic diseases. The review included 25 studies and 12,579 older adults, highlighting the potential benefits of managing co-existing chronic illnesses in a coordinated manner.
A new analysis of the LEADER trial suggests liraglutide treatment reduces the risk of death from heart attack and nonfatal stroke in people with Type 2 diabetes, regardless of their cholesterol levels. The study found that liraglutide also lowers LDL-C levels, an important marker of developing heart disease.
Research suggests that very high HDL cholesterol levels may increase the risk of heart attack and death, contrary to traditional views. The study found a U-shaped curve in the relationship between HDL cholesterol levels and cardiovascular risk, with both low and extremely high levels increasing the risk.
Guidelines recommend inducing labour or caesarean section at 40 weeks to minimize pregnancy risks, particularly for women with congenital heart disease. Women with heart disease face higher mortality risk during pregnancy compared to healthy counterparts.
The British Heart Foundation is launching a £30 million global cardiovascular challenge to identify and solve the biggest problems in heart and circulatory disease. The Big Beat Challenge will bring together world-leading researchers and innovators to accelerate breakthroughs that could transform lives across the globe.
The Lancet study estimates that one in three people drink alcohol, with 2.2% of women and 6.8% of men dying from alcohol-related health problems each year. The risk of death increases rapidly with higher levels of consumption, offsetting any potential protective effects against cancer, injuries, and infectious diseases.
A study of 35,132 individuals found that unstable drinking patterns over time may increase heart disease risk, while consistent moderate drinking within recommended guidelines may have a cardioprotective effect. Consistency in drinking behavior is crucial for reaping the benefits.
Research suggests that moderate drinking within recommended guidelines may have a cardioprotective effect, but unstable patterns over time increase the risk of coronary heart disease. Consistency is key, and lifestyle changes, such as retirement, may also play a role in differing risks.
The American College of Cardiology recommends incorporating smoking cessation into cardiovascular care, with a focus on evidence-based treatments. Community and policy-level interventions, such as smoke-free laws and education campaigns, also play a crucial role in reducing tobacco-related heart disease risk.
Chagas disease, caused by a parasite, has spread to the US and other countries, carrying a high risk of heart disease. Early detection is critical for treatment, which can be cured with medications having a 60-90% success rate.
Researchers found that young, healthy individuals with elevated LDL cholesterol are still vulnerable to cardiovascular disease and coronary heart disease, even with a low 10-year risk. Lifestyle interventions and cholesterol-lowering medication may be necessary for these individuals to achieve healthy LDL levels.
Researchers found that treatments restoring blood flow to the lower limbs of people with critical limb ischemia can lead to longer survival and reduced healthcare costs compared to amputation. The study analyzed Medicare records of over 72,000 patients diagnosed with primary critical limb ischemia between 2010 and 2015.
Scientists developed a method to characterize the genetic contributions to traits and diseases, revealing that cognitive traits and psychiatric disorders are influenced by tens of thousands of gene variants. The study provides a 'big picture' of genetic influences, useful for designing future genetic studies.
A large international study found that individuals consuming average amounts of sodium (3-5g/day) do not face increased health risks. However, those exceeding five grams a day may experience cardiovascular events, and improving dietary quality with potassium-rich foods can mitigate this risk.
A diverse diet may actually lead to consuming more calories and increasing the risk of weight gain. Instead, experts recommend prioritizing a balanced eating pattern that emphasizes whole foods such as fruits, vegetables, whole grains, and lean proteins.
People with younger-onset type 1 diabetes have a higher risk of cardiovascular complications and premature death. The study found that those diagnosed before the age of 10 had a 30-times greater risk of serious cardiovascular outcomes than those in the general population.
A recent study published in the Journal of the American Heart Association found that older adults who spend less time sitting and more time engaged in light to vigorous physical activity benefit from healthier levels of heart and vessel disease markers. The results showed that increased physical activity was particularly beneficial for...
Research reveals that routine screening and genetic testing can identify up to 30% of relatives with an underlying genetic predisposition to developing life-threatening aortic diseases. This could lead to earlier detection and potentially save lives.
Researchers found that obese women had a thicker left ventricle, lower E/A ratio, and higher systolic blood pressure compared to normal or overweight women. These changes may explain their predisposition to preeclampsia and cardiovascular complications during pregnancy.
A new study finds that long term abstinence from alcohol and heavy drinking are associated with an increased risk of dementia. The researchers found that every 7 unit a week increase in consumption was associated with a 17% increase in dementia risk among those drinking above 14 units a week.
Unsheltered homeless adults in Boston experience significantly higher mortality rates due to noncommunicable diseases and substance use. The study found that avoiding shelters increases the risk of death among this subpopulation, highlighting the need for targeted interventions.
Research suggests that higher body mass index (BMI) can cause changes in the heart's structure and function in young adults, including thicker vessel walls and increased blood pressure. The study used genetic analysis to uncover evidence of a causal link between BMI and cardiovascular measurements.
Researchers discovered 44 chromosomal regions linked to abnormal heart rhythms, including atrial fibrillation and heart block. The study's findings could lead to better treatments and a greater understanding of the heart's electrical activity.
Death rates from heart disease, stroke, and certain cancers are higher in low- and middle-income tropical countries compared to high-income Western nations. Chronic diseases, such as diabetes and cardiovascular diseases, account for 90% of deaths in Western countries due to late diagnosis and inadequate treatments.
A new study, based on a subgroup of KEEPS participants, found no effects of hormone therapy cessation on carotid artery intima-media thickness. The results support the use of hormone therapy for menopause symptom relief or bone loss prevention, with potential benefits on heart disease reduction.
A global study found that people infected with HIV are twice as likely to suffer from heart disease, with the greatest impact in sub-Saharan Africa and Asia Pacific regions. The study highlights the need for targeted treatments to maximize resources in countries with limited healthcare funding.
New research from the American Heart Association found that regular physical activity can reduce the risk of first and recurrent heart attacks, even in areas with moderate-to-high levels of traffic pollution. Moderate cycling for four or more hours per week cut the risk of recurrent heart attack by 31 percent.
A new study found that low-carb diets can improve artery flexibility in women, even if men lose weight more, suggesting a potential benefit for pre-diabetic women. This improvement in artery flexibility reduces the risk of developing serious heart conditions.
A nationally representative study found that cardiovascular mortality rates increased rapidly in rural India and surpassed urban areas between 2000 and 2015. Younger adults, particularly those born after 1970, are at the highest risk of death due to heart problems caused by narrowing of the heart's arteries.
A new study found that post-traumatic stress disorder (PTSD) in blue-collar workers who responded to the World Trade Center plane attack on September 11, 2001, may increase their risk of heart attack and stroke. The study, published in Circulation: Cardiovascular Quality and Outcomes Journal, included over 6,800 non-firefighter workers...
A new grant will explore the use of genome editing to modify human pluripotent stem cells for cardiac treatment. This approach could lead to unlimited production of cardiac cells in the lab for therapy, reducing the need for heart donors.
A new study found Indonesia's life expectancy increased by eight years between 1990 and 2016, but non-communicable diseases have dramatically risen. The 'double burden' poses significant health challenges, with heart disease, diabetes, and injuries taking a toll on the population.
A new study found that middle-aged individuals with high fitness are 56% less likely to die from heart disease after a depression diagnosis. Dr. Madhukar Trivedi recommends steps to boost exercise success, including consistency, tracking progress, and varying exercises.
A new study published in LGBT Health found that bisexual men have a higher risk for heart disease compared to heterosexual men, with increased rates of mental distress, obesity, and elevated blood pressure. Researchers highlight the importance of tailored screening and prevention strategies to reduce heart disease risk in bisexual men.
Researchers used gene editing and stem cell technologies to predict genetic variants associated with hypertrophic cardiomyopathy, a condition that can lead to sudden cardiac death. The study showed promise for improving the accuracy of gene variant interpretation and diagnostic testing.
Researchers found that positive results for glucose and HbA1c in one blood sample are a highly accurate predictor of diabetes and major complications. The study suggests a single blood sample may be sufficient to diagnose diabetes, potentially reducing the need for repeat tests.
A pooled analysis of 2 million people aged 42-77 from Europe to Asia suggests marriage protects against heart disease/stroke. Being single, divorced, or widowed increases cardiovascular risk, with divorce associated with a 35% higher risk of developing heart disease.
A web-based tool called KardioKompassi provided personalized genetic risk information to patients and doctors, leading to significant changes in smoking cessation and weight loss rates. The results showed that nearly 90% of participants made better health care choices after receiving their genomic data.
A new clinical trial found that combining wearable devices with financial incentives and personalized goal-setting significantly increased physical activity levels among ischemic heart disease patients. After financial incentives were stopped, the incentive group continued to increase their physical activity.
A clinical trial by University of Pennsylvania School of Medicine shows that combining wearable devices with financial incentives and personalized goal-setting increases physical activity levels in heart disease patients. The study found a significant increase in step counts, totaling about 100 miles more than the average patient in co...
The adult ventricular septum plays a crucial role in both the right and left ventricles' performance. Advanced imaging techniques reveal its mechanical patterns, which may help predict adverse cardiovascular events.
An observational study tracking over 100000 men and women found that job strain is associated with a higher risk of premature death in men with coronary heart disease, stroke, or diabetes. Despite achieving treatment targets, men experiencing job strain had a 68% greater risk of death compared to those with no job strain.
New research suggests that regular exercise has a greater impact on blood vessels in middle-aged men compared to post-menopausal women. Arterial stiffness and blood pressure improved with brisk walking, but were higher in women after exercise.
A new review published in Progress in Cardiovascular Diseases found that plant-based diets can prevent and reverse atherosclerosis, reducing the risk of cardiovascular disease by 40%. Plant-based diets are rich in fiber and phytonutrients, which reduce inflammation and oxidative stress, while animal products are high in saturated fat a...
A new study by the American Heart Association found that high protein diets may be associated with a small increased risk of heart failure in middle-aged men. The study followed 2,441 men over an average of 22 years and found that those who consumed more protein had a slightly higher risk of developing heart failure.
A study of over 2,800 postmenopausal women found that a higher proportion of male to female sex hormones was associated with a significant increase in cardiovascular disease risk. The researchers suggest that having a more male-like hormone profile may affect heart disease risk independent of other risk factors.