Research on the causes and treatment of heart disease. Covers light exposure and heart health, sex differences, heart-in-a-dish models, and cardiac risk.
Women who take antibiotics for two months or more are at increased risk of cardiovascular disease, especially in late adulthood and middle age. The study found that long-duration antibiotic use was associated with an increased risk of heart attack and stroke in women aged 60 or older.
Two proteins, glucocorticoid receptor and mineralocorticoid receptor, work together to support heart health in mice. The study's findings may lead to the development of therapeutic compounds that help people with an increased risk of a heart attack by regulating cortisol levels.
The Framingham Heart Study, the nation's longest-running cohort study, has been renewed for an additional six years and $38 million from the National Heart, Lung, and Blood Institute. Researchers will examine the elderly groups and younger cohorts to better understand aging and determinants of health and disease in older people.
A study found that a resting heart rate of 75+ beats per minute in mid-life is associated with a doubling in the risk of an early death from all causes. Men in their 50s with increased heart rates are at heightened risk of developing heart disease over the next 11 years.
Trodusquemine has shown promise in stimulating heart muscle regeneration in mice after an artificially induced heart attack, and slowing heart and skeletal muscle degeneration in a mouse DMD model. Novo Biosciences aims to develop a dosing regimen for juvenile DMD patients and define toxicity in juvenile animal models.
Research reveals that chronic diseases significantly decrease mobility in older adults without them realizing it, affecting physical activity levels. Exercise therapies tailored to the type of disease can improve physical functioning and independent living possibilities.
A new study by RAND Corporation found that graphic health warning labels on cigarette packages can deter some adults from purchasing tobacco products, particularly those with lower nicotine dependence. However, the strategy is unlikely to influence those smokers who are most addicted to nicotine.
Researchers at Yale University tested a text message intervention aimed at improving heart health in Chinese patients with heart disease. The study found that although the texts did not produce the desired outcome, patients liked the messages and wanted them to continue.
A new study published in Advances in Nutrition reveals that refined grains are not associated with increased disease risk and premature death. Refined grain intake was found to have an inverse association with total cancer deaths and a statistically significant inverse association with all-cause death rate.
Researchers found counties in expansion states had about four fewer deaths from heart disease per hundred thousand residents compared to non-expansion states. This translates to approximately 1,800 fewer deaths per year in areas that expanded Medicaid coverage under the ACA.
Researchers found that Aronia berries resistant to heat during production of cornmeal porridge, retaining antioxidant content. The study highlights the potential of super berries like Aronia for functional foods like porridge.
An observational study of over 7,500 people aged over 50 found that a quarter reported age discrimination, which was associated with fair or poor health and serious health problems. The study highlights the need to tackle ageism to improve health and wellbeing in older people.
A study published in Experimental Physiology found that shift work can have a long-term effect on the risk of heart disease and diabetes. Shift work was shown to negatively impact the breakdown of triglycerides and sugar utilization in the body, increasing the risk of these diseases.
Researchers at MUSC have shown that restoring the enzyme's ability to produce nitric oxide can help protect against heart disease in lupus patients. The study suggests that this approach could also be relevant to heart disease more broadly, by promoting endothelial cell function and reducing inflammation.
A recent publication touted genetic risk scores as a tool for identifying patients at high risk of heart disease, cancer, and diabetes. However, a new study questions the value of these scores, finding they have lower accuracy when considering individual patient factors.
A recent study published in the Journal of Aging and Health found a significant association between having five or more children and an increased risk of heart disease in adults. The research, led by Sara Hipp at the University of Hawaii at Manoa, analyzed data from nearly 25,000 participants aged 50 and older.
A study by Massachusetts General Hospital reveals that over a third of individuals in recovery have chronic physical diseases related to previous substance use. The presence of these diseases significantly reduces participants' quality of life and is associated with lower life expectancy.
Researchers found that Asian subgroups have varying risks of death from heart disease and stroke, with women losing more years due to stroke. The study identified unique risks for each subgroup, including cerebrovascular disease affecting Vietnamese and Filipino men and women, resulting in lost life expectancy.
A new cardiac-specific comorbidity index outperforms existing general indexes in predicting death after hospital admission for patients with heart disease. The index was derived from administrative data and tested on almost 19,000 cardiac patients in Alberta.
A new Australian study found that mothers who breastfeed are 34 percent less likely to die of heart disease than those who don't. Women who breastfed for up to 12 months had a lower risk of developing and dying from cardiovascular disease, with significant findings independent of socio-economic status and overall health-related lifestyle.
Researchers at University of Cambridge found link between chronic inflammation and increased risk of depression and heart disease. Inflammation-related proteins IL-6 and CRP were identified as biomarkers for depression.
A new study by University of Central Florida researcher Ramon Hinojosa reveals that veterans are more prone to cardiovascular morbidity and conditions earlier than non-veterans, possibly due to modern warfare, diet changes and increased rates of obesity and mental illness.
A study of over 27,000 heart attack patients found an increase in heat-induced heart attacks in recent years, particularly among individuals with diabetes or hyperlipidaemia. Climate change is suspected to be a contributing factor, but the exact mechanism behind these deaths remains unclear.
A new scientific study found a 30-year gap between countries with the highest and lowest ages at which people experience health problems equivalent to those of an average 65-year-old. The United States ranked 54th, between Iran (69.0 years) and Antigua and Barbuda (68.4 years).
Research suggests that yo-yo dieting may increase women's heart disease risk by making it harder to control various risk factors. Women who experienced weight cycling reported lower scores on the American Heart Association's Life's Simple 7 score.
The study found that activity of the ActRII pathway increases with aging and heart failure, leading to cardiac dysfunction. Inhibiting this pathway can improve cardiac function in animal models of heart failure, suggesting a potential new treatment strategy for the deadly disease.
Preliminary research found that adding high-quality plant-based foods to a diet decreases the risk of deaths from heart disease. A 10-point increase in score on a healthy plant-based diet scale was associated with a 10% lower risk of cardiovascular disease death.
Researchers developed a microrobot that can reach accurate locations of cardiovascular disease, such as Chronic Total Occlusion, and move towards desired directions inside complicated blood vessels. This innovation increases the success rate of treatment and shortens surgery time.
A recent study published at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2019 reveals that young women in the US tend to worry more about stress and mood disorders than their heart health. The research, which surveyed 331 young women ages 15-24, found that only ...
A Rutgers study found that smokers perceive snus as less harmful for lung cancer and heart disease but more harmful for oral cancer. The researchers suggest that quitting tobacco is the best course of action, while switching to snus may reduce risks for non-quitters.
Researchers at Clemson University developed a targeted nano therapy that destroyed calcium buildup in arteries without causing side effects. The therapy mimics a human's chronic kidney disease and has the potential to benefit thousands of patients.
Researchers created a bioreactor to study heart tissue's mechanics in sync with the body's beats, revealing changes in force similar to those observed in living hearts. The device allows for adjustment of contraction parameters to mimic normal or disease conditions, enabling studies on high blood pressure's effects on heart cells.
Research highlights psychosocial stress and its impact on cardiovascular disease in women, particularly younger women and ethnic minorities. The unpredictability schema may contribute to heightened CVD risk in women, emphasizing the need for targeted prevention strategies.
The article highlights the challenges in predicting and stratifying cardiovascular risk in women due to sex-specific factors, traditional risk models' flaws, and inadequate representation of women in CVD research. This has led to a persistent gap in awareness, diagnosis, and treatment of ischemic heart disease in women.
Peripartum cardiomyopathy (PPCM) is a disorder where heart failure develops during or after pregnancy. Recent studies suggest angiogenic imbalance plays a key role, with soluble fms-like tyrosine kinase-1 (sFlt1) and prolactin being important factors. The latest IPAC study recommendations are also referenced.
The study examines the relationship between obstructive sleep apnea (OSA) and cardiovascular disease (CVD) in women, highlighting sex differences and conflicting evidence. The authors argue that more studies are needed to better understand OSA's impact on CVD outcomes in women, leading to personalized care.
UVA is expanding its telehealth capacity to help patients manage chronic conditions like diabetes, prediabetes, and heart disease. The initiative includes remote monitoring, screenings, home rehabilitation programs, and training for healthcare providers.
A study of 1.7 million Chinese adults found 10% at high heart disease risk, yet only 3% taking statins or aspirin for prevention. The low uptake is attributed to a lack of awareness among patients and providers in China.
Diabetes mellitus increases risk of stable ischemic heart disease, with trial data showing no benefit from nuclear stress tests or cardiac computed tomography. Revascularization for SIHD also does not reduce mortality or myocardial infarction rates in diabetic patients without symptoms.
The article highlights the need for a practical approach to defining the elderly population and provides an evidence-based review of diagnostic and therapeutic implications of advanced age in ischemic heart disease. This knowledge gap affects risk-benefit ratios of pharmacotherapies and percutaneous coronary interventions.
For patients with stable ischemic heart disease, aggressive risk factor modification and optimized medical management are crucial. Novel agents like ivabradine improve treatment options for symptom control in patients unresponsive to current treatments.
Researchers have developed a new technique to simultaneously measure blood clotting and the formation of free radicals, shedding light on their role in blood vessel damage and disease development. The discovery could lead to better treatments for conditions like heart disease, stroke, and vascular dementia.
This special issue of Cardiovascular Innovations and Applications Journal covers key aspects of stable ischemic heart disease, including contemporary management strategies and epidemiology. The collection of reviews and commentary provides insights into the latest research and clinical practices for this condition.
A study of 81,714 postmenopausal women found that drinking multiple diet drinks daily was associated with a higher risk of stroke, especially small artery strokes. The research highlights the potential health risks of artificially sweetened beverages and recommends limiting their use.
Researchers at Baylor College of Medicine have made a groundbreaking finding that enables the reprogramming of adult cardiomyocytes to promote heart tissue regeneration. By manipulating the genetic mechanisms that prevent cardiomyocyte proliferation, scientists have successfully opened up possibilities for treating heart disease.
A new study suggests that coeliac disease permanently replaces 'tissue-healing' T cells with 'pro-inflammatory' T cells in the bowel, causing chronic inflammation and potentially contributing to other intestinal disorders. The research has implications for gut health in affected patients.
Researchers found that PTSD is associated with an increased risk of cardiovascular disease, but a combination of physical disorders and psychiatric conditions may explain the association. Veterans with PTSD are 41% more likely to develop circulatory and heart disease than those without PTSD.
Researchers discovered a previously unknown mechanism between the brain, bone marrow, and blood vessels that appears to protect against hardening of arteries when sleep is healthy. Disrupted sleep leads to increased inflammation and atherosclerosis in mice, highlighting the importance of quality sleep for cardiovascular health.
Researchers at Johns Hopkins Medicine have discovered a molecular switch that regulates mTORC1 activity, slowing its action and preventing abnormal heart enlargement. This discovery has potential implications for treating heart disease, diabetes, kidney, lung, cancer, and autoimmune disorders.
A new review highlights the importance of identifying premenopausal women with elevated risk factors, such as ovarian dysfunction and pregnancy complications. These women should be screened early for cardiovascular disease and receive close follow-up and lifestyle modifications.
A study published in the Journal of the American Geriatrics Society found that depression symptoms are linked to an increased risk of death in older adults. The research suggests that heart disease and stroke may play a role in this connection, but preventing heart disease is not enough to prevent or delay death.
A new noninvasive technique has been developed to simulate repairs to the heart's mitral valve with high levels of accuracy. This will enable surgeons to provide patient-specific treatments, potentially reducing recurrence rates after surgery.
Researchers found that all Brexit scenarios would reduce fruit and veg intake, with a no-deal Brexit being the most damaging. This led to an estimated 12,400 additional CVD deaths in England between 2021 and 2030.
A no-deal Brexit is predicted to result in the greatest price hikes for imported fruits and vegetables, leading to a substantial drop in intake. This could contribute to an estimated 12,400 extra cardiovascular deaths over the next decade in England.
A new study finds that offspring whose mothers had complicated pregnancies may be at greater risk of heart disease later in life. The research suggests that the prenatal environment can directly influence long-term cardiovascular health. Antioxidant therapy during pregnancy could potentially protect against heart disease in offspring.
A longitudinal study of 2,256 participants found that moderate to high financial stress increased the risk of developing heart disease in African Americans. The study suggests a possible relationship between financial stress and heart disease, which clinicians should be aware of.
The study found that participants who slept less than six hours were 27% more likely to have atherosclerosis compared to those who slept seven to eight hours. Poor quality sleep also increased the risk of atherosclerosis, with participants waking during the night or experiencing frequent movements during sleep being at higher risk.
A study published in The Lancet reveals that consuming at least 25g to 29g of dietary fibre per day can reduce the risk of non-communicable diseases such as coronary heart disease, stroke, type 2 diabetes, and colorectal cancer by 16-24%. Whole grains also show promise in reducing mortality rates and incidence of these diseases.
A new study published in PLOS Medicine found that individuals with two or more chronic diseases incur significantly higher healthcare costs compared to those with a single disease. The study analyzed data from New Zealand and estimated the annual health expenditure per person for six non-communicable disease classes.
Research suggests that abdominal obesity may have evolved as a protective mechanism against infections in individuals who experienced poor fetal nutrition. This study proposes that the hallmark of obesity, visceral adipose tissue, provides immunity against abdominal infections.