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Causes of death in rheumatoid arthritis patients

Rheumatoid arthritis patients have higher mortality rates due to complications from the disease and its treatment. Cardiovascular and respiratory conditions, including pneumonia, are major contributors to these deaths.

SourceWiley·JournalArthritis Care & Research·DateMar 7, 2018

A trip to the mountains despite a heart condition?

High-altitude exposure affects cardiovascular systems differently for various individuals. Experts recommend maximum altitudes and caution when taking medications. Hiking can have a positive effect on disease progression and psychological well-being for those following guidelines.

SourceEurac Research·JournalEuropean Heart Journal·DateFeb 20, 2018

The American Stroke Association receives $11.1 million gift from the Henrietta B. and Frederick H. Bugher Foundation to fund targeted research network in hemorrhagic stroke

The American Heart Association/American Stroke Association has received a $11.1 million gift from the Henrietta B. and Frederick H. Bugher Foundation to fund targeted research in hemorrhagic stroke. The centers will employ precision medicine, data analysis, and core collaborative research to prevent and treat this type of stroke.

More than 100,000 switches

A research team led by Dr. Ralf Gilsbach and Prof. Dr. Lutz Hein from the University of Freiburg has mapped out the gene regulators in the DNA of human cardiac muscle cells for the first time. They discovered over 100,000 gene switches that control gene activity, providing insight into mechanisms misdirected in heart disease.

SourceUniversity of Freiburg·JournalNature Communications·DateJan 29, 2018

Heart cells sense stiffness by measuring contraction forces and resting tension simultaneously

Researchers at Queen Mary University of London discovered a new mechanism by which heart cells sense stiffness, involving both contraction forces and resting tension. The study found increased resting tension in heart cells after a heart attack or disease, leading to abnormal mechanosensing and signalling that contributes to heart fail...

SourceQueen Mary University of London·JournalDevelopmental Cell·DateJan 25, 2018

Women who have gestational diabetes in pregnancy are at higher risk of future health issues

Research found that women diagnosed with GDM were over 20 times more likely to develop type 2 diabetes, nearly twice as likely to develop hypertension, and almost twice as likely to develop ischemic heart disease. The study highlights the need for targeted risk factor management to improve long-term metabolic and cardiovascular outcomes.

SourceUniversity of Birmingham·JournalPLOS Medicine·DateJan 16, 2018

Gestational diabetes points toward heightened risk of heart disease

A retrospective cohort study found that women diagnosed with GDM have a significantly increased risk of developing type 2 diabetes, ischemic heart disease, and hypertension. The study highlights the importance of targeted risk factor management to improve long-term metabolic and cardiovascular outcomes.

SourcePLOS·JournalPLOS Medicine·DateJan 16, 2018

Scientists identify a key mechanism regulating a protein required for muscle and heart function

Researchers have identified a crucial mechanism in the regulation of titin protein, a key player in skeletal muscle and heart function. The study found that disulfide bonds play a significant role in determining titin's elastic properties, and their formation can cause major changes in the protein's elasticity.

UK obesity levels among the worst in Europe -- heart disease statistics from more than 45 countries

The study reveals huge inequalities persist with heart disease accounting for over 50% of all deaths in many middle income countries, compared to less than 30% in high income countries. The UK has the highest prevalence of adult obesity in males and 2nd highest in females, and ranks joint 5th for raised blood cholesterol.

SourceQueen Mary University of London·JournalEuropean Heart Journal·DateNov 27, 2017

Price changes for seven foods could save thousands of lives per year, study says

A new study suggests that altering prices of seven dietary items could prevent an estimated 23,000 deaths per year in the US. The study found that subsidies for healthy foods and taxes on unhealthy foods could reduce deaths from stroke, diabetes, and cardiovascular disease, especially among Americans with lower socioeconomic status.