Articles tagged with Hypertension
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Researchers have identified ten new genes associated with salt sensitivity and hypertension in rats, which may help develop a treatment regimen for hypertensive patients. The study used DNA microarrays and a global gene screening tool to analyze the genetics of salt-sensitive hypertension.
A study of 297 patients found a significant prevalence of renal artery narrowing among those with hypertension. The researchers recommend considering abdominal aortography to better define cardiovascular risk and monitor kidney function.
A genetic variant in the adducin gene has been found to be associated with a significant reduction in heart attack and stroke risk when patients take low-dose diuretics. The study found that individuals with this variant were twice as likely to avoid cardiovascular events when treated with diuretics.
A study of 643 women found that C-reactive protein (CRP) levels are an indicator of increased cardiovascular risk in people with no signs of heart disease. Regular exercise has been shown to decrease blood pressure in all groups of people, regardless of their weight or ethnicity.
A study of dialysis patients found that high pulse pressure is associated with a greater risk of death, contradicting the idea that lower blood pressure is better. Researchers analyzed over 37,000 patients and discovered that the difference between systolic and diastolic blood pressures can indicate mortality risk.
The LIFE study found that losartan prevented more cardiovascular events and deaths than atenolol, even after similar reductions in blood pressure. Additionally, a second study showed losartan's effectiveness in reducing cardiovascular risk for patients with diabetes and left ventricular hypertrophy.
Researchers have discovered genetic variations associated with high blood pressure, enabling a predictive test for hypertension risk. The test detects GRK4 protein variations linked to sodium elimination errors, significantly increasing lifetime risk.
A study of 641 older women with hypertension found that ACE inhibitor users had slower declines in walking speed and muscle strength. The results suggest that these drugs could be used to delay disability in older adults, potentially improving their quality of life.
A study published by Massachusetts General Hospital found that moderate alcohol consumption may lower the risk of developing hypertension in young women. The research, based on data from over 70,000 women aged 25 to 42, shows a J-shaped curve where light drinkers have a decreased risk compared to nondrinkers and heavier drinkers are at...
Researchers found that cocaine increases blood pressure by stimulating the heart to cause rapid heartbeat and increased cardiac output. This elevation can lead to damage of vital organs such as the heart, brain, and kidney. The study's findings may lead to new treatment strategies for cocaine-induced blood pressure elevation.
A recent NHLBI study found that 90% of middle-aged Americans are at risk of developing high blood pressure, with a significant decrease in the past 25 years due to improved treatment. Lifestyle changes such as a healthy diet, regular exercise, and moderate alcohol consumption can help reduce this risk.
Researchers investigate whether genetics are the sole cause of high blood pressure in Hispanic populations, finding that environment plays a key role. The study reveals that physical activity and reduced smoking/salt use can help prevent high blood pressure in this demographic.
Researchers have identified key genes associated with cardiac hypertrophy, hypertension, and dilated cardiomyopathy. Genetic testing is also being developed to predict susceptibility to coronary artery disease, offering new avenues for preventive medicine.
A study conducted in Harlem found that 30% of adult residents suffer from oral health problems, with those with public insurance only slightly more likely to receive care due to limited provider availability. The high rates of unemployment and lower household income may be contributing factors.
A study of 1,507 people with diabetes found that 71% are aware of their high blood pressure and 57% take medication, yet control rates remain inadequate. Effective treatment strategies are needed to address the disparities in blood pressure control among people with diabetes.
A recent NHLBI study found that the DASH diet and reducing dietary sodium can lower blood pressure in diverse populations, including those with hypertension, older adults, and younger individuals. The study's findings suggest that these lifestyle changes can benefit Americans of all ages, backgrounds, and health statuses.
A recent study found that blood pressure-lowering drugs have varying effects on heart attacks and strokes. Researchers argue that existing testing methods may not accurately reflect a drug's true effectiveness.
The ACCESS study confirms that Atacand improves outcomes for patients with acute ischaemic stroke and high blood pressure. Early treatment with Atacand reduces the risk of total mortality, cerebral complications, and cardiovascular complications by 47.5 percent.
A study by Northwestern University researchers found that men who smoke are more likely to experience erectile dysfunction due to the negative effects of smoking on blood vessels. The prevalence of erectile dysfunction in former smokers was similar to that of never-smokers, highlighting the long-term risks of tobacco use.
A study found that people with normal or high-normal blood pressure can progress to hypertension over a four-year period, positively associated with age and weight increase. The authors recommend annual screening for those with high-normal blood pressure, while normal pressure individuals may require biennial screening.
Research suggests that daily exposure to aircraft noise may raise blood pressure levels. People living in areas with higher average or maximum noise levels are more likely to develop hypertension.
A new NHLBI study found that high-normal blood pressure increases the risk of heart attack, stroke, and heart failure by 1.5 to 2.5 times in 10 years compared to optimal blood pressure levels. The study also showed a continuous increase in cardiovascular events with age, especially in older adults.
A meta-analysis of 27 trials involving over 136,000 people found that lowering high blood pressure is the most important effect of all drug treatments, with little difference between various drugs used. The study's results support the importance of detecting and treating raised blood pressure to prevent cardiovascular disease.
Research finds that treating high-risk older adults with hypertension is more effective at preventing cardiovascular events than those with lower risk levels. The study suggests that doctors should not hesitate to treat patients with multiple risk factors.
A large study has found that retinal blood-vessel damage is associated with an increased risk of stroke. Damage to the small blood vessels in the retina was linked to a doubling of stroke risk, regardless of age, sex, or other health factors.
A new analysis of studies shows that behavioral interventions, including counseling and training programs, can significantly improve blood pressure management. More than 4,000 participants benefited from these programs, which offered improved blood pressure control over usual care.
A recent study by UT Southwestern Medical Center has identified a significant number of undiagnosed hypertension and diabetes cases in the Dallas County population. The project aims to reduce death and disability from coronary heart disease through analysis of collected data.
A study found that depression is associated with self-reported hypertension, but this relationship does not exist when blood pressure is measured clinically. Lifestyle factors such as obesity, sedentary lifestyles, and stress are more strongly linked to high blood pressure.
Researchers have developed a new experimental drug that significantly reduces arterial pulse pressure, improving the blood vessels' ability to stretch by about 14%. The study suggests that this medication may represent a novel therapeutic approach for patients with age-related vascular stiffening and systolic hypertension.
A new drug breaks down collagen bonds in blood vessels, reducing stiffness in older individuals. This could be a treatment for high blood pressure, heart failure, and diabetes complications.
Researchers at Yale University have identified a genetic cause of high blood pressure, a condition that affects 25% of adult populations. The study found two genes that contribute to the disease, which is linked to increased salt reabsorption and diminished potassium secretion in the kidneys.
A new study published in Psychosomatic Medicine found that African-Americans who report higher levels of religious belief have lower blood pressure. The study measured blood pressure and 'religious coping' in 155 participants and found a significant relationship between the two, with African-Americans experiencing lower blood pressure.
A panel of seven renowned experts, including Henry Black and Jay Cohn, reviewed RESPeRATE's progress and results from six clinical studies. The board expressed excitement about the potential for breathing exercises to modify the cardiovascular system and further evidence of RESPeRATE's effectiveness as a non-drug option to lower high b...
A study by UB researchers found that more than half of survivors diagnosed with uncontrolled high blood pressure still had hypertension, and 46% of those with dangerously high cholesterol continued to have high levels. This highlights the need for improved secondary prevention strategies in the US population.
A study published in Ethnicity and Disease found that cocaine use and hypertension are major risk factors for brain hemorrhage in young African Americans. The researchers also discovered that the incidence of intracerebral hemorrhage is nearly 50 times higher in African Americans than in white patients.
A UCSF study reveals that uninsured patients with chronic illnesses face significant challenges in managing their conditions, including poor symptom recognition and limited access to medication. This can lead to greater illness severity and premature death. Free community clinics are crucial for addressing these disparities.
Researchers found elevated levels of endocannabinoid anandamide and CB1 receptors in cirrhotic liver samples, suggesting a novel approach for managing vasodilation and portal hypertension. Elevated levels of anandamide may also reduce blood pressure.
Distinguished leaders Bryant, Robertson, and Warfel were honored for their dedication to the American Heart Association. The organization has grown to include over 22.5 million volunteers and supporters, dedicating $337 million to research support and community programs.
Neuropathic Postural Tachycardial Syndrome (NPTS) affects approximately 500,000 people in the U.S., primarily women between 20 and 45. Researchers Dr. Giris Jacob and Dr. David Robertson found that NPTS can be caused by genetic mutations or disease after surgery, pregnancy, or inflammatory illness.
Research suggests that personality's role in high blood pressure may be less clear-cut than previously thought. The study found no evidence supporting the 'hypertensive personality hypothesis', contradicting previous findings that linked specific personality traits to hypertension. However, researchers speculate that personality may pl...
A study published by the American Academy of Neurology found that diabetes and high blood pressure can lead to cognitive decline in middle-aged people. The research, which examined 10,963 participants aged 47-70, showed a modest but statistically significant association between these conditions and cognitive abilities.
A six-year study of people aged 40-70 found that those with diabetes and high blood pressure experience greater cognitive decline compared to their healthy counterparts. The study suggests controlling hypertension and diabetes before age 60 may help preserve mental abilities later in life.
A recent NHLBI study found that reducing sodium intake, combined with either a typical U.S. diet or the DASH diet, substantially lowered blood pressure in persons with high blood pressure and those at higher than optimal blood pressure levels. The DASH-Sodium study found that lower sodium intake resulted in lower blood pressures for bo...
A study published in Archives of Internal Medicine found that unhappy marriages increase blood pressure in people with mild hypertension, while good marriages are protective. Participants who experienced marital discord had a statistically significant thickening of the heart's left ventricle after three years.
A new study found that people in unhappy relationships with mild high blood pressure experience sustained increases in blood pressure, while those in loving relationships show a decrease. The research suggests that marital distress may be a significant factor in raising blood pressure in vulnerable individuals.
Researchers found that combining a long-acting AT1-receptor blocker with an ACE inhibitor reduces blood pressure and albumin excretion in hypertensive type 2 diabetic patients. The study also showed that combined treatment is more effective than using either drug alone.
Researchers found that calcium channel blockers (CCBs) were significantly less effective at preventing heart attacks, heart failure, and cardiovascular events compared to ACE inhibitors, beta-blockers, and diuretics. The study analyzed over 27,000 patients and showed a 26% higher risk of heart attack among CCB users.
A new study found that blacks have a higher mortality rate than whites after coronary artery bypass surgery (CABG), with hypertension being a significant factor. The study suggests that blacks may be more prone to severe and frequent ventricular hypertrophy, an enlargement of the heart's chambers.
A study by American Heart Association finds that consuming heavy meals may trigger heart attacks, increasing risk by about four times within two hours. The research suggests that eating a large meal can lead to temporary rises in blood pressure and heart rate, potentially causing heart attacks or strokes.
A new study suggests that losartan, a type of hypertension medication, may improve sexual function in men with high blood pressure. After 12 weeks of treatment, 88% of hypertensive males with sexual dysfunction reported improvement in at least one area of sexuality. The drug also showed promise in improving overall quality of life.
A Johns Hopkins study found that one-third of Korean Americans have high blood pressure, with almost 75% not controlling it. The prevalence is 32%, much higher than the American rate of 24% and Korean rate of 22%. English-speaking ability directly impacts hypertension control among Korean Americans.
New research suggests angiotensin-(1-7) levels may predict and prevent preeclampsia. The hormone helps regulate high blood pressure during normal pregnancy.
The new report clarifies how to monitor and treat pregnant women with hypertension before and during pregnancy. It highlights the importance of differentiating between hypertension and preeclampsia, a condition that affects the placenta, kidney, liver, and brain, and can lead to severe complications for both mother and child.
Deleting the b1 subunit of the BK channel in mice causes high blood pressure and enlarged hearts, suggesting it as a promising target for anti-hypertension drugs. The study provides a new model for investigating the molecular basis of hypertension.
A study in mice found that genetic background influences blood-pressure response to acute alcohol exposure, with some strains experiencing increased blood pressure and others not. The findings suggest a predisposition to greater increases in blood pressure with alcohol consumption, potentially leading to hypertension.
A study by the NIH found that ACE inhibitors and beta blockers significantly reduced kidney failure risk compared to calcium channel blockers. High blood pressure management has improved stroke and heart disease risks, but kidney failure remains a concern for African Americans.
Research demonstrates that increased Akt1 function is sufficient to produce tetraploid smooth muscle cells in hypertensive or aging arteries. Cyclin B degradation is prematurely triggered in these cells, allowing for extra rounds of DNA synthesis and cell growth.
A study of 27,743 patients found that long-acting calcium channel blockers increased the risk of heart attacks and congestive heart failure by 26% and 27%, respectively. The findings suggest that alternative antihypertensive drugs like diuretics, beta-blockers, and ACE inhibitors may be more effective in preventing cardiovascular events.
The DASH diet, known for its blood pressure-lowering effects, also reduces homocysteine levels, a risk factor for heart disease. Participants on the DASH diet had lower homocysteine levels compared to those on a control diet or one rich in fruits and vegetables.
In 1975, medicinal chemists Miguel A. Ondetti and David W. Cushman designed captopril, the first of an innovative class of drugs controlling high blood pressure and heart disease.