Articles tagged with Hypertension
A study of 1,148 hypertensive patients with type 2 diabetes found that tight blood pressure control reduced the incidence of diabetic retinopathy and visual loss by 47% over seven years. The researchers discovered a lower risk of microaneurysms and blindness in the tight BP control group compared to those with less stringent policies.
A systematic review of studies found that atenolol had no significant effect on reducing death from all causes, cardiovascular causes, or incidence of heart attack. However, it showed a trend towards reduced stroke incidence and increased mortality compared to other antihypertensive drugs.
Researchers found that populations near the equator have a functional protein for salt retention, while those in cooler climates have a mutant gene producing a dysfunctional protein. This correlation suggests a shared selective pressure and could change disease gene hunting strategies.
Studies examining prehypertension reveal a significant increase in heart disease and stroke risks among affected individuals. Prehypertension is associated with unfavorable levels of other major cardiovascular disease risk factors and contributes to a substantial burden on the healthcare system.
A study by University of Illinois Chicago researchers found that nearly 60% of American adults have elevated blood pressure, with prevalence increasing among older adults, those with lower education levels and obesity. Awareness and management of hypertension remain low, particularly among Mexican-Americans.
A study found that a mitochondrial mutation may contribute to the development of metabolic syndrome, a cluster of disorders including high blood pressure and high cholesterol. Researchers discovered the link in a four-generation family affected by hypertension, hypercholesterolemia, and other conditions.
A single genetic mutation in mitochondrial genes has been found to be associated with multiple risk factors for heart disease and stroke, including hypertension, high cholesterol, and low magnesium levels. The researchers also discovered a link between the mutation and other conditions such as hearing loss and weakened heart muscle.
A review of 136 studies found bariatric surgery to be effective in achieving significant weight loss, with an average percentage of excess weight loss of 61.2%. The procedure also showed promise in resolving or improving four obesity-related disorders: diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea.
A multi-center randomized controlled study found that 45 minutes of weekly self-treatment with RESPeRATE significantly reduces systolic blood pressure, with greater reductions in medicated and non-medicated patients. The device's effectiveness was correlated with slow breathing time, making it easy to use at home.
A study of over 150,000 women found that folate intake was associated with a lower risk of high blood pressure. The most significant effects were seen in younger women, who had a 29% lower risk of developing hypertension when consuming high amounts of folate.
A large study found that teenagers with insulin resistance are at a higher risk of developing high blood pressure as adults. Insulin resistance, a precursor to diabetes, was linked to increased systolic blood pressure and obesity in the long-term study.
African-American communities benefit from education programs that lower blood pressure readings. Researchers also found that changing sleeping positions can alter blood pressure, with stomach-lying positions leading to a significant drop in systolic blood pressure. Furthermore, impaired kidney function significantly increases the risk ...
Researchers warn of potential cardiovascular risks associated with the use of modafinil, a new alertness medication. A low-salt diet has also been shown to protect arteries in people with resistant hypertension, according to the study.
Two studies found that isometric hand-grip (IHG) exercise significantly lowered systolic blood pressure in participants with hypertension. Additionally, IHG improved carotid artery distensibility, while having no effect on peripheral arteries. The researchers suggest that these improvements may be due to enhanced endothelial function.
A 20-year study found that high blood pressure is associated with a decline in cognitive function in both younger and older adults. The research emphasizes the importance of reducing blood pressure levels in younger individuals to prevent cognitive decline.
A study led by Mount Sinai School of Medicine researchers found that imidazole-4-acetic acid-ribotide may be a primary cause of high blood pressure and a molecular link to diabetes. The molecule binds to receptors in the brain, leading to elevated blood pressure, which can also impair insulin release.
A recent study published in the Journal of Dental Education found that nearly half of patients with high blood pressure at a dental clinic had never been diagnosed. The researchers advocate for regular blood pressure screening in dental offices, which could help identify hypertension early and prevent related health issues.
Yale researchers found strong clinical evidence to support treating systolic blood pressure of at least 160 mm Hg in older adults. Treatment decisions should prioritize patient preferences and tolerance of therapy due to limited evidence on benefits.
Studies found strong evidence supporting treatment of systolic hypertension in older persons with SBP of at least 160 mm Hg. Treatment guidelines recommend thiazide diuretics and long-acting calcium channel blockers as first-line therapy for SH. Despite effectiveness, poor control of SH among patients is increasing.
A study of 4,223 individuals found that subclavian artery stenosis is a significant risk factor for hypertension. Patients with peripheral arterial disease are five times more likely to have SS.
A study found that about 21% of middle-aged Americans have both high blood pressure and high LDL-cholesterol, significantly increasing heart attack risk. The combined effect was 51 cases per 10,000 person-years, much higher than expected.
The Donald W. Reynolds Foundation has awarded UT Southwestern a $12 million grant to continue the Dallas Heart Study, which aims to develop new biotechnology and treatments for heart disease. The study has already made significant discoveries, including identifying key chemical signals that change stem cells into heart cells.
According to a recent study, approximately 65 million US adults now have hypertension, a 30% increase from the previous decade. The rise is largely due to the growing prevalence of obesity and an aging population.
A study of 154 hospitalized stroke patients found that antihypertensive therapy was used more frequently than recommended by clinical guidelines. The majority of patients experienced relative hypotension, and one in 20 developed frank hypotension.
A recent study found that nearly half of adults with hypertension also have high cholesterol, which can be treated with existing medications. However, many individuals are not receiving adequate treatment for their cholesterol problems, highlighting the need for aggressive management of both conditions to prevent cardiovascular disease.
A study of 5,115 young adults found that those who react to psychological stress with spikes in blood pressure are more likely to develop high blood pressure in their 40s. The research suggests that assessing blood pressure changes in response to stress may be a useful tool for determining future risk.
A study of 300 people found that those with more abdominal fat were four times more likely to develop hypertension. Meanwhile, a six-year study of middle-aged men found no correlation between regular aerobic exercise and reduced artery thickening.
A study of 3,140 patients found pioglitazone to lower blood pressure in both Stage I and Stage II hypertension cases. This effect could reduce cardiovascular disease risk factors in patients with type 2 diabetes.
The study found that BENICAR and Benicar HCT helped patients reach aggressive blood pressure goals, with nearly 69.3% achieving less than or equal to 130/85 mmHg after 16 weeks. Additionally, BENICAR was found to be more effective in reaching blood pressure goals compared to other ARBs like Cozaar and Diovan.
The prevalence of blood pressure control among hypertensive individuals declines with advancing age, particularly in women. According to the study, only 32% of men and 24% of women aged 80 and older had their blood pressure under control.
New guidelines from Thomas Jefferson University offer more precise classification of blood pressure in children and adolescents based on gender, age, and height. Pediatricians are encouraged to recommend diet, exercise, and weight control counseling for children with prehypertension.
A recent study found that average blood pressure levels among American children and teenagers have increased over the past two decades. The new clinical practice guidelines will provide updated recommendations for lifestyle and drug therapies to address this trend.
A study found that caffeine consumption is associated with increased systolic blood pressure in adolescents, particularly those who consume more than 100mg of caffeine per day. The researchers suggest that high caffeine intakes may be a marker for unhealthy dietary and lifestyle practices that increase the risk of hypertension.
Researchers investigate protein regulators of inflammation and hypertension, aiming to find direct cause-and-effect relationship between the two. The study could lead to new targets for treating high blood pressure, a major risk factor for heart disease.
A new study published in the American Journal of Hypertension demonstrates that 15 minutes of daily RESPeRATE treatment significantly reduces home blood pressure in both medicated and non-medicated patients. The study also shows high patient compliance, with many patients continuing treatment after the trial ended.
The study analyzed medication use patterns in 133,624 hypertensive patients in Pennsylvania and found that switching to evidence-based antihypertensive regimens could reduce costs by nearly a quarter. Adherence to these guidelines is crucial for affordability of prescription drug benefit programs.
Researchers found that black women with high blood pressure during pregnancy had the highest homocysteine levels, while white women had lower levels. The study suggests increasing folic acid intake among blacks to mitigate this risk. Homocysteine levels are influenced by diet and genetic factors.
Researchers found that exercise-induced high blood pressure may be caused by cells failing to relax and expand blood vessels. This impairment can be a common factor among various risk factors for heart disease, including aging, menopause, and diabetes.
A specific mutation in the KCNMB1 gene is associated with lower blood pressure, according to a study published in JCI. Researchers found that individuals with this mutation had lower diastolic blood pressure compared to those without it. The study suggests that targeting the beta1 subunit may have therapeutic potential for treating hyp...
A gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with a lower prevalence of diastolic hypertension. The beta1 subunit of the Ca2+-sensitive K+ channel protects against hypertension, as outlined in an accompanying commentary.
A study found that 156 inner-city black adolescents who practiced transcendental meditation twice daily for four months lowered their daytime blood pressures, with an average drop of 3.5 millimeters in systolic pressure and 3.4 millimeters in diastolic pressure.
A recent study found that moderate amounts of alcohol may help prevent death from cardiovascular disease (CVD) in men with hypertension. The study involved 14,125 male physicians and showed a significant reduction in CVD mortality among those who drank moderately.
A study of 4,939 elderly patients with hypertension found that home blood pressure testing was more accurate than office tests in predicting cardiovascular events. Home blood pressure testing showed a 17.2% increased risk of cardiovascular events for each 10-mm Hg increase in systolic blood pressure.
Researchers found a strong relationship between increasing blood pressure and CVD risk in women, with even borderline elevations associated with an increased risk. The study of 5,218 female health professionals showed that for each 10 mm Hg increase in systolic blood pressure, CVD risk rose by 9 percent.
Researchers found a strong correlation between obesity and high blood pressure in children aged 8-17. The prevalence of high blood pressure increased by 4.2% among overweight children, 3.5% among obese children, and 2.6% among normal-weight children over 10 years.
A study analyzing physician office data and pharmacy surveys found that the cost of high blood pressure therapy increased by $12 billion between 1990 and 2002. The primary contributors to this increase were higher prices for expensive ACE-inhibitors and ARBs, as well as a decline in diuretic prescriptions.
The study found that patients who used home blood pressure monitoring were more likely to stop taking antihypertensive drugs and had lower costs, but also had less BP control. Self-measurement helped identify white-coat hypertension, supporting a step-wise strategy for evaluating blood pressure.
Researchers found that achieving basal growth hormone levels of less than 2.5 µg/liter and glucose-suppressed GH levels of less than one µg/liter may not minimize cardiovascular risks in acromegaly patients. Instead, these patients are at increased risk for conditions like hypertension, diabetes, and osteoarthritis.
The study found that lifetime stroke risk is 21% in women at age 55, while men have a 17% risk. Blood pressure significantly increases the risk of stroke across all ages. Lifestyle changes to control blood pressure can reduce stroke risk.
Researchers found that elevated sFlt-1 levels and low PlGF levels can predict the development of preeclampsia. Women with preeclampsia also have lower VEGF levels, which may contribute to the condition's health problems.
A survey of primary care doctors found that those who favored prescribing expensive medications were more likely to provide patients with free drug samples from pharmaceutical representatives. This may lead to a bias towards prescribing more expensive options, despite their comparable effectiveness to cheaper alternatives.
Screening for proteinuria is not recommended for the general population due to high costs and false positive/negative test results. However, targeted screening for hypertensive patients aged 30+ and adults 60+, or less frequent screenings every 10 years, can be cost-effective.
A study published in The Journal of the American Medical Association found that fitness in young adulthood can significantly reduce the risk of developing high blood pressure, diabetes, and metabolic syndrome. Improving fitness levels by 50% or more can decrease these risks by as much as 50%.
A large observational study found that improving fitness in healthy young adults can significantly reduce the risk of developing high blood pressure, diabetes, and metabolic syndrome. Regular physical activity can help maintain a healthy weight and protect heart health, even after age-related changes.
A large study found a positive association between increasing levels of C-reactive protein and risk of developing hypertension. Women with higher levels of this inflammatory marker were about twice as likely to develop high blood pressure over a median follow-up period of 7.8 years.
The International Verapamil-Trandolapril Study (INVEST) found that older hypertensive patients with coronary artery disease treated with a calcium antagonist strategy or a beta-blocker had similar outcomes. The study included over 22,500 patients and followed them for an average of 2.7 years.
Researchers found that women with hypertension in the SYMPHONY trials received more and different agents to reduce blood pressure than men, yet showed no significant difference in blood pressure control. The study highlights opportunities for improving medical therapy and outcomes in women.
Researchers at the Emory Heart Center found that oral tetrahydrobiopterin can significantly lower blood pressure in patients with poorly controlled hypertension. The study showed a significant reduction in blood pressure after just three weeks of therapy, likely due to increased availability of nitric oxide and enhanced vasodilation.
The SCOPE study found a significant 42% relative risk reduction in fatal/non-fatal strokes in the Atacand group compared to the control group. The study showed that Atacand offers important clinical benefits by reducing the risk of stroke in elderly patients with isolated systolic hypertension.
Researchers found that overweight boys experience greater increases in blood pressure during stress, but their ability to restore normal pressures is impaired. In contrast, overweight girls have a more effective natural mechanism for reducing blood pressure, which may be attributed to the effects of estrogen.