Articles tagged with Hypertension
Researchers found that estrogen depletion exacerbates diastolic dysfunction and increases blood pressure in rats fed a high salt diet. The study suggests that estrogen may protect against hypertension and renal damage caused by excess salt intake.
A new study found that mice with high blood pressure are more susceptible to cardiac complications when taking painkillers due to a chemical imbalance between prostacyclin and thromboxane. This imbalance can lead to hypertension, enlarged hearts, and severe scarring of the heart.
Researchers found that a decline in prostacyclin led to cardiac complications, including hypertension and heart scarring, in mice prone to high blood pressure. Aspirin may protect against this damage by blocking unrestrained thromboxane actions.
A new European consensus definition of the metabolic syndrome (MetS) reveals a high prevalence, with 38% of men and 36% of women affected. The MetS is associated with increased cardiovascular mortality rates, particularly in diabetic women, highlighting gender-specific risk factors.
The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) found that newer antihypertensive drugs, such as amlodipine and perindopril, were more effective than standard diuretic or ß-blocker therapy in reducing blood pressure and preventing major cardiovascular events. The study showed a significant reduction in stroke events and fewer cas...
Half of high blood pressure patients reporting no medical care or guidance, despite 50 million adults affected. Guidelines for ER evaluation and management needed to address this issue.
A study of over 4,000 women found that taking high doses of acetaminophen and ibuprofen may increase the risk of developing high blood pressure. Women taking these painkillers were more likely to develop hypertension compared to those who didn't use them.
A study by the Framingham Heart Study found that despite increasing rates of high blood pressure with age, treatment rates for older adults remain low. Seventy-four percent of people aged 80 and older have high blood pressure, but only a minority receive treatment.
A study found that blood pressure control is suboptimal in older women with hypertension, with only 28% of women in this age group achieving controlled blood pressure. The researchers also noted that treatment rates are high, but the use of cost-effective thiazide diuretics is low.
A study found that nearly three-quarters of elderly individuals (80+ years) have hypertension, with women facing greater risks. Poor control rates were 38% among men and 23% among women, mainly due to inadequate use of combination therapy.
A study found that inhaling salt particles causes significant increases in blood pressure, putting factory workers at risk. Wearing protective gear can mitigate this effect.
Researchers at UT Southwestern discovered that WNK1 activates SGK1, leading to sodium ion channel activation and increased blood pressure. The study suggests that genetic factors may play a role in salt-sensitive hypertension., Genetic factors may contribute to hypertension in certain population groups.
Diabetics with hypertension can significantly reduce cardiovascular disease risks by taking diuretics, according to a new study. The medication has been shown to be more protective against heart failure and stroke in patients with diabetes and high blood pressure.
A recent study published in Archives of Internal Medicine found diuretics to be equally protective against fatal coronary heart disease or non-fatal heart attacks among people with diabetes. Additionally, diuretics were shown to be more effective in lowering systolic blood pressure and reducing the risk of congestive heart failure.
The American Academy of Neurology has released new guidelines for treating essential tremor, recommending medications such as propranolol and primidone to reduce limb tremors. Surgery is also an option when drug therapy is ineffective, with deep brain stimulation found to be more effective than thalamotomy in reducing tremors
The American Academy of Neurology has published a new guideline recommending medications such as propranolol, primidone, sotalol, and atenolol to treat limb and head tremors in patients with essential tremor. These medications can help manage tremors and improve daily life.
African-American patients have a higher rate of increased heart weight, or left-ventricular hypertrophy, than whites regardless of their differences in body fat and overall body composition. Elevated blood pressure is the best indicator of why African-Americans in the study had a higher rate of left-ventricular hypertrophy.
Benicar-based treatment algorithms significantly reduced mean systolic blood pressure in Stage 2 hypertensive populations. In Stage 1 patients, 89% reached the aggressive blood pressure goal of less than 130/85 mmHg.
Scientists Tiruppattur V. Ramakrishnan and Sergio Henrique Ferreira receive the first Trieste Science Prizes for their groundbreaking research in physics and biological sciences. Their work has led to significant breakthroughs in understanding quantum transport, nanoscopic systems, and the treatment of hypertension and chronic pain.
A study of 1,475 people found moderate to severe sleep apnea increases stroke risk by 3-4 times over four years. The risk is double that of other well-known factors like high blood pressure and obesity.
A new combination of irbesartan and hydrochlorothiazide reduced systolic blood pressure by an average of 21.5 points in 77% of patients, with 83% achieving acceptable diastolic blood pressure levels. The study included diverse patient groups and showed significant results.
A new analysis found that a non-drug device-guided slow breathing treatment reduced the white-coat effect by ~80% in patients, compared to ~40% for controls. The treatment was also effective across different patient groups, including pre-hypertensives and resistant hypertensive patients.
A new study from Ohio State University found that patients taking lisinopril were more likely to have their prescriptions refilled on time if the medication came in a blister package. The researchers also noted a significant reduction in diastolic blood pressure among patients who received blister packages.
Researchers used a novel transgenic strategy to create ProC mice with low protein C levels, which spontaneously developed thrombosis and inflammation. The study found that maternal ProC is required for sustaining pregnancy, highlighting the role of protein C in development and disease.
A randomized trial of 202 participants showed a 23% reduction in all-cause mortality, a 30% reduction in cardiovascular disease mortality, and a 49% reduction in cancer mortality. The study found that Transcendental Meditation reduces risk factors for heart disease and other chronic disorders.
Older adults with mild hypertension did not experience significant reductions in blood pressure through exercise alone, according to a new study. However, those who lost fat and gained muscle showed more substantial benefits.
The ALLHAT study confirms diuretics are superior to newer drugs in lowering blood pressure and preventing complications. Diuretics were also found to be more effective in reducing high blood pressure and preventing stroke in black patients.
The ALLHAT study found that diuretics are superior to calcium channel blockers and ACE inhibitors in lowering blood pressure and preventing heart failure. Diuretics were also more effective in reducing high blood pressure and stroke in black patients, supporting the use of diuretics as first-line therapy for high blood pressure
A study of ALLHAT trial data reveals that thiazide-type diuretics are superior to ACE inhibitors and calcium channel blockers in reducing cardiovascular disease incidence and heart failure in both black and non-black patients. Diuretic-based treatment also showed reduced risk of myocardial infarction and fatal coronary heart disease.
Research found that Viagra increased fetal weights to normal values and completely prevented fetal resorption, suggesting beneficial effects on maternal uterine vascular adaptation and fetal health. The study's selective effect on the uteroplacental circulation avoids complications of antihypertensive therapy during pregnancy.
Research reveals kidneys and other systemic tissues have distinct roles in controlling blood pressure, challenging the dominant view that kidneys play a central role. The findings suggest that maximal efficacy of hypertension drugs requires complete blockade of receptors in both kidney and outside of kidney.
Researchers at the University of California, Irvine, have found that electroacupuncture can reduce elevated blood pressure by up to 50 percent in rats. The study suggests that acupuncture may be an effective complement to other medical treatments for patients with hypertension and cardiovascular diseases.
African-American stroke survivors with obesity have a higher risk of cardiovascular disease and metabolic syndrome. The study found that nearly all patients were overweight or obese, with diabetes increasing with BMI, and that class three obesity significantly increases the risk of recurrent stroke.
The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) found that a new treatment strategy for hypertension reduced the risk of strokes and heart attacks by 25% and 15%, respectively. The new strategy, combining calcium channel blocker amlodipine with angiotensin converting enzyme inhibitor perindopril, outperformed traditional therapy ...
A new algorithm calculates the ratio of three specific proteins in urine and blood to identify severe preeclampsia with high sensitivity and specificity. This approach may provide a more accurate diagnosis than current tests, which can be confusing and lead to premature birth.
Researchers found that black adolescents who practiced transcendental meditation for eight months experienced a significant improvement in the ability of their blood vessels to dilate, reducing their risk of cardiovascular disease. This finding suggests that meditation may be an effective way to prevent and treat heart disease.
A new study reveals that sleep loss significantly increases cardiovascular disease risk in alcoholics, disrupting heart rate and sympathetic catecholamine levels. Behavioral treatments may help alleviate sleep abnormalities and related physiological issues.
People with migraine are 43% more likely to be smokers and have high cholesterol, while those with aura symptoms are more likely to have high blood pressure and history of stroke or heart disease. The study suggests a shared predisposition toward both conditions.
A meta-analysis of 19 randomized trials found COX-2 inhibitors significantly associated with blood pressure elevation compared to NSAIDs and placebos. This increased risk may be clinically significant for patients at elevated cardiovascular risk, particularly in the elderly population.
Researchers have identified two genomic regions associated with hypertension in African Americans, which can help locate genes affecting the condition. The study uses a genome-wide scan to compare genetic variations between African and European populations.
Alcohol contributes significantly to global health, with 4% of the global burden attributed to it. Raising prices and reducing availability can lower consumption and mortality rates. However, ineffective policies hinder progress in controlling excessive drinking.
Recent studies on COX-2 inhibitors have found that celecoxib may not increase blood pressure, while rofecoxib does, and that these drugs are safe for patients with type 2 diabetes. However, patients taking warfarin with COX-2 inhibitors or NSAIDs have an increased risk of upper gastrointestinal hemorrhage.
A large multiethnic cohort study found that midlife cardiovascular risk factors, such as diabetes and high cholesterol, are strongly linked to an increased risk of dementia in later life. The study also suggests that treating these risk factors may reduce the risk for dementia.
A recent Stanford study has identified a link between genetic differences in African-Americans and an increased risk of hypertension. The research, which analyzed the genetic profiles of over 270 individuals, suggests that specific genes in regions near chromosomes 6 and 21 may contribute to high blood pressure risk in African-Americans.
Researchers at Johns Hopkins Medicine found that sildenafil can treat enlarged hearts by blocking the breakdown of cyclic GMP, a key molecule involved in heart stress. The study showed significant improvements in heart function, including increased contractility and cardiac output, even after hypertrophy had developed.
A recent study published in JAMA found that higher folate intake is associated with a decreased risk of hypertension in women. Younger and older women who consumed at least 1,000 micrograms of total folate daily had a lower risk of developing hypertension.
The global prevalence of high blood pressure is expected to increase from a quarter to a third by 2025, totaling over 1 billion adults. Developing countries are projected to bear the brunt of this increase, with three-quarters of the world's population with high blood pressure in these regions.
A new study published in Nutrition Reviews finds that a vegetarian diet can lower blood pressure and reduce the risk of stroke, heart attack, and kidney failure. By analyzing 80 scientific studies, researchers found that individual patients experience blood pressure-lowering effects from a plant-based diet.
A recent study published in BMC Medicine reveals that environmental factors are a major contributor to higher blood pressure among African Americans, contradicting the long-held assumption of a genetic predisposition. The research found significant variations in hypertension rates across different populations worldwide.
A study of 2,609 participants found that drinking outside of meals significantly increases the risk of hypertension. The research also showed that the volume of alcohol consumed played a more important role in the relationship between drinking and high blood pressure than how often a person drank.
Researchers found that diuretics plus calcium channel blockers doubled CVD death risk compared to diuretics plus beta-blockers. Monotherapy with calcium channel blockers also increased CVD death risk by 55%.
A study found that exposure to anger, negative emotions, or sudden changes in body position can increase the risk of stroke by up to 14 times within two hours. The study examined 200 people with ischemic strokes and found a link between these triggers and stroke, potentially offering new avenues for prevention and intervention.
Researchers found that bosentan treatment led to significant improvements in clinical and hemodynamic parameters of severe pulmonary arterial hypertension. A simpler method to determine optimal CPAP pressure for treating obstructive sleep apnea was also developed, showing improved results with auto-adjusted devices. Molecular methods w...
A novel AT2R gene transfer approach has been shown to prevent hypertension-related enlarged heart, cardiac fibrosis. The study found that the procedure prevented the heart from enlarging and prevented thickening of the ventricular walls.
A Medical College of Georgia study found that individuals with higher lean body mass can better regulate their blood pressure in response to stress. This is because fitness allows the body to efficiently excrete sodium, which helps lower blood pressure back to normal.
A new study reveals that obesity is tied to an increased risk for numerous health conditions, including life-threatening diseases like heart failure and serious illnesses like high blood pressure. The research also found a correlation between excess weight and various health complaints that reduce quality of life.
A positive family history of stroke increases young women's risk of both blocked and ruptured vessel strokes. High blood pressure and smoking are also strong predictors of rupture-risk, while diabetes and lack of exercise contribute to blockage-risk.
A University of Toronto study identifies immigration, lack of partner support, and readiness for hospital discharge as factors increasing new mothers' risk of developing depressive symptoms. Early detection can lead to early intervention and improved maternal and child outcomes.
Researchers found that masked hypertension, a blood pressure condition where patients have lower office readings but higher 24-hour averages, poses an independent risk for target organ damage. Emotion-cognitive variables play a significant role in how patients appraise the seriousness of their heart attack symptoms.
Researchers identified Gq signaling pathway as crucial in hypertension, finding that inhibiting this pathway could lead to new therapies for high blood pressure patients taking multiple drugs.