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Science News for April 1, 2005


JCI table of contents May 1, 2005

A novel vaccine against Pseudomonas aeruginosa has been successfully tested in mice, inducing antibody production and protection against the deadly bacteria. The vaccine uses a modified adenovirus vector expressing a region of the bacteria's outer membrane, which was previously recognized as a promising vaccine candidate.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateApr 1, 2005

American Thoracic Society Journal news tips for April 2005 (first issue)

A study of 752 French patients found that shorter graft ischemic times were associated with improved long-term survival after single or double lung transplantation. The median ischemic time was 240 minutes, and a cutoff time of 330 minutes was identified as best discriminating between survivors and non-survivors.

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateApr 1, 2005

Mesoamerican book wins archaeology book award

The SAA's Book Award recognizes 'Ancient Mexico & Central America' for its impact on archaeological research and understanding of Mesoamerica's cultural history. The book, written by Penn State adjunct professor Evans, is an informative and fun guide to the region.

How lupus T cells lose IL-2

Researchers found that sera from lupus patients contain antibodies that bind to T cells and suppress IL-2 production through CaMKIV. This deficiency in IL-2 contributes to the autoantibody production seen in lupus, highlighting a new understanding of how microenvironment influences defective T cell function.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateApr 1, 2005

JCI table of contents April 1, 2005

Researchers found no causative MEF2A mutations in patients with premature coronary heart disease, contradicting previous findings. The study suggests that another gene may be responsible for the heart disease, casting doubt on the role of MEF2A in CAD.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateApr 1, 2005

Highlights of the April 2005 Journal of the American Dietetic Association

A study published in the Journal of the American Dietetic Association found that mothers who consumed more fruits and vegetables were less likely to pressure their daughters into eating, resulting in less picky eating habits. The researchers also discovered that girls' consumption of fiber was significantly lower among picky eaters.

SourceAmerican Dietetic Association·JournalJournal of the American Dietetic Association·DateApr 1, 2005

New vaccine means bye-bye to bacteria in the lung

A novel genetic vaccine against Pseudomonas aeruginosa has been developed using a modified adenovirus vector expressing a region of the outer membrane called OprF. Immunization with this vaccine induces antibody production and protects mice from deadly doses of the bacteria, even after repeated exposure.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateApr 1, 2005

Purdue scientists unravel Midwest tornado formation

A Purdue University study found that many tornadoes form from 'line-shaped' storms associated with large weather fronts, particularly in the Midwest. These tornadoes are more likely to occur late at night and in colder months, challenging traditional notions of severe weather patterns.

SourcePurdue University·JournalWeather and Forecasting·DateApr 1, 2005

Climatologists discover deep-sea secret

A research team has confirmed that ocean circulation in the southern hemisphere adapts to sudden changes in the north, enabling more accurate forecasts of ocean reactions to climate change. The study reveals a mechanism linking the two hemispheres, with waters in the southern hemisphere playing an active role in sudden climate changes.