A new study published in the JAMA Network found that clopidogrel pretreatment significantly reduced the odds of cardiovascular death, heart attack, or stroke following PCI by 46% compared to treatment at the time of PCI. Pretreatment also resulted in a 41% reduction in cardiovascular death from randomization through 30 days.
Researchers have discovered the closest living descendant of the extinct giant deer, a species that once roamed the UK. The fallow deer was found to share key characteristics with the ancient animal, including flattened antlers and similar skull and teeth features.
SourceUniversity College London·JournalNature·DateSep 4, 2005
The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) found that newer antihypertensive drugs, such as amlodipine and perindopril, were more effective than standard diuretic or ß-blocker therapy in reducing blood pressure and preventing major cardiovascular events. The study showed a significant reduction in stroke events and fewer cas...
SourceThe Lancet_DELETED·JournalThe Lancet·DateSep 4, 2005
Scientists at EMBL and IRB-PCB found that disrupted genes in stem cells can lead to deadly tumors. The study shows that specific molecules control cell division and differentiation, and their disruption can result in cancer.
SourceEuropean Molecular Biology Laboratory·JournalNature Genetics·DateSep 4, 2005
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Melanoma cells can efficiently spread due to reactivation of dormant Slug gene, which enables swift travel through the body. This discovery sheds light on why melanoma metastasizes at an earlier stage than other cancers.
SourceWhitehead Institute for Biomedical Research·JournalNature Genetics·DateSep 4, 2005
A study by Professor Peter Openshaw suggests a link between reduced childhood infections and increased asthma prevalence, highlighting the importance of early exposure to dirt. The 'hygiene hypothesis' proposes that a lack of environmental factors can lead to immune system imbalances, making individuals more susceptible to diseases.
Researchers found that most human embryonic stem cell lines exhibit gross genetic changes after a year to three years of growth in the lab. These changes can affect chromosome numbers, gene expression, and mitochondrial DNA sequences. The study highlights the need for close monitoring and further investigation into the effects of these...
SourceJohns Hopkins Medicine·JournalNature Genetics·DateSep 4, 2005