Articles tagged with Hypertension
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Researchers at Oregon State University discovered that aging blood vessels lose elasticity due to a breakdown in cellular signaling. A complex enzymatic process explains how this occurs, involving phosphorylation and ceramide synthesis. Diet rich in fruits and vegetables may help slow down this natural process.
Researchers have confirmed that veins stiffen as we age, a change that may contribute to high blood pressure. Regular exercise training may help maintain vein flexibility. The study, led by William Farquhar from the University of Delaware, recruited healthy young and older adults and monitored their blood flow.
Two editorials in the American Journal of Hypertension argue that the TROPHY study is flawed due to its unusual definition of incident hypertension. The studies caution that the treatment may not be effective in preventing the development of hypertension, and instead suggest that it could cause a slow unmasking of high blood pressure.
A new study from Harvard Medical School and Brown Medical School shows that racial disparities in care cannot be attributed to low-performing health plans. The research found that high-performing plans and low-performing plans have comparable levels of disparities in key health measures.
A study published in JAMA found that black patients in Medicare managed care health plans experience poorer treatment outcomes for common conditions like high blood pressure, diabetes, and high cholesterol. The disparity in quality of care was largely attributed to within-plan disparities rather than differences across health plans.
A recent study from Brown Medical School and Harvard Medical School found significant racial disparities in Medicare managed care plans, even among high-performing plans. Blacks were more likely to have poor control of cholesterol, blood pressure, and blood sugar levels compared to whites.
A study estimated 25% of Pakistan's population is overweight or obese, with 10% classified as obese. Lower BMI cutoff values may be needed to accurately identify conditions and healthy targets due to associated risks of hypertension and diabetes.
A recent study published by the American Heart Association found that children with high blood pressure are at risk for sleep breathing disorders. Researchers discovered that 60% of hypertensive children had sleep disordered breathing, which can lead to daytime fatigue, poor school performance, and increased blood pressure.
Researchers identified a gene mutation that regulates smooth muscle contraction and blood pressure in rats, leading to hypertension. The study may lead to improved treatments by targeting the proliferation of smooth muscle cells.
A study found that insulin resistance in early teens may predict a higher risk of developing type 2 diabetes and cardiovascular disease in adulthood. Insulin resistance was linked to increased blood pressure, high triglycerides, and low HDL cholesterol levels.
Researchers found that high blood pressure causes hearts to have lower fat metabolism, relying more on carbohydrates for energy. This shift can lead to impaired heart function and increased risk of heart failure.
A study found that drinking flavanol-rich cocoa improved blood vessel function in both young and older adults. This suggests that flavanol-rich cocoa may be a useful dietary approach for maintaining endothelial vessel function, particularly in the aging population.
A Johns Hopkins study shows that moderate exercise has no negative impact on the heart's ability to pump blood or increase in size. Exercise improves heart function and reduces abdominal fat, benefiting those who make gains in physical fitness.
A new scoring system can help determine which patients are at the lowest risk of dying after gastric bypass surgery. The system is based on five easy-to-identify patient characteristics and provides a standardized way to compare outcomes among centers performing the surgery.
A study found that increased nighttime blood pressure may be associated with a higher risk of developing congestive heart failure. Analyzing data from 951 elderly men, researchers discovered that a 9–mm Hg increase in nighttime ambulatory diastolic blood pressure and non-dipping blood pressure patterns were significant predictors of CHF.
Researchers found that healthy black girls experience a significant drop in estrogen levels during stress, leading to increased blood pressure and elevated risk of heart disease. In contrast, white teens maintain consistent estrogen levels, reducing their blood pressure response to stress.
Researchers investigate sodium channel genes to identify genetic predictors of hypertension and develop screening methods for high blood pressure in the general population. A study involving 300 healthy youth will measure sodium handling after environmental stress and analyze their genes to correlate with impaired natriuresis.
A re-examination of beta-blocker efficacy for hypertension treatment found that the risk of stroke is more significant for patients over 60 years old. In contrast, younger patients under 60 show no increased stroke risk. The meta-analysis suggests a potential shift in beta-blocker usage guidelines.
Researchers have developed a non-invasive method to detect atherosclerosis by measuring coronary blood flow, allowing for early detection and treatment of high-risk patients. The study found that elevated levels of interleukin-6 are a major determinant of coronary endothelial dysfunction in individuals with hypertension.
Researchers found that intermittent stresses like high blood pressure cause cardiac abnormalities before the heart enlarges. Exercising mice showed enlarged hearts without damage, while hypertensive mice exhibited structural and cellular changes early on.
A study using RESPeRATE, a device-guided paced breathing system, found significant reductions in blood pressure and peripheral resistance in hypertensive patients. The treatment group showed a greater systolic BP reduction correlated with the total time spent in slow breathing.
The Canadian Institutes of Health Research has invested $900,000 over five years to fund the first Canadian Chair in Hypertension Prevention and Control. Dr. Norm Campbell will lead a multi-faceted approach to primary prevention and treatment of hypertension.
The World Hypertension League is calling for better awareness of high blood pressure patients reaching the internationally-recognised goal of 140/90mmHg or lower. Despite this, around 50-70% of people with high blood pressure worldwide remain above this goal, leaving them at significant risk of cardiovascular disease.
A study at Mayo Clinic found that patients treated with shock wave therapy for kidney stones were at higher risk of developing diabetes and hypertension, with risks nearly four times and one-and-a-half times respectively. The researchers believe the association may be due to damage inflicted on the pancreas or scarring in the kidneys.
Researchers have identified novel drug therapies, including endothelin antagonists and prostacyclin, that improve quality and quantity of life for patients with PAH. These treatments offer hope for patients who previously faced lung transplantation.
Researchers found that each year of treatment reduced the risk of developing dementia by about 3 percent. Long-term hypertension can damage brain blood vessels, but this study suggests benefits for cognitive function with proper treatment.
Scientists used RNA interference to block a mineralocorticoid receptor, which signals the body to absorb sodium and water into the bloodstream. The treatment kept blood pressure from worsening but did not eliminate it, and significantly reduced kidney damage in rats.
A study published in Annals of Internal Medicine found that participants who made multiple lifestyle changes, such as improving their diet and increasing physical activity, had a greater reduction in high blood pressure than those who did not make any changes. The intervention group that followed the DASH eating plan saw the most signi...
A recent study found that diabetes care has improved over the past decade, but two in five people with diabetes still have poor control of cholesterol and blood pressure. Lifestyle changes can significantly reduce the risk of heart disease for those with mild hypertension.
Research finds that short sleep duration is associated with a higher risk of developing hypertension, particularly among middle-aged adults. The study analyzed data from over 4,800 participants and found that those who slept for five or fewer hours per night had a 24% chance of developing high blood pressure.
A recent study by the American Heart Association found that people who slept for five or fewer hours per night were more likely to develop hypertension than those who slept seven or eight hours. This association was observed even after controlling for other risk factors, such as obesity and physical activity.
A study found that sleep apnea treatment improved the shape and pumping action of the heart, reducing high blood pressure and daytime sleepiness. Treatment with continuous positive airway pressure (CPAP) devices also reduced cardiovascular risks and improved overall health outcomes in patients.
A University of Chicago study found that lonely individuals have significantly higher blood pressures than non-lonely people, even after accounting for other factors. The researchers discovered a strong link between loneliness and increased blood pressure in aging adults, with the greatest differences observed among older participants.
A study by WHO found that haemorrhage was the leading cause of maternal death in Africa and Asia, while high blood pressure was responsible for most maternal deaths in Latin America and the Caribbean. The review highlights the need for increased emphasis on programs to prevent and treat postpartum haemorrhage.
A recent study by UC Davis researchers found that grape seed extract can significantly reduce blood pressure in individuals with metabolic syndrome. The one-month study involved 24 patients, who experienced an average drop of 12 millimeters in systolic and 8 millimeters in diastolic blood pressure.
The study found that patients with extreme obesity who underwent gastric bypass surgery experienced significant reductions in blood pressure. The majority of these patients were able to reduce or eliminate their blood pressure medications after surgery, while those with normal blood pressure showed no significant changes.
A study of 347 patients who underwent bariatric surgery between 1992 and 2001 found a significant reduction in blood pressure 18 months post-surgery. Systolic and diastolic blood pressures decreased, with those without hypertension or taking antihypertensive medications experiencing smaller drops.
A four-year study of over 800 patients with pre-hypertension found that treatment with candesartan cilexetil significantly reduced the risk of developing hypertension. The study suggests that early intervention may be an effective way to prevent the disease's progression.
The Trial of Preventing Hypertension study found that early treatment with candesartan reduced the risk of developing hypertension in patients with high normal blood pressure. The study showed a significant benefit from preventive therapy, but lifestyle modification had little effect on public health.
Research shows that high-risk hypertensive patients are frequently prescribed antihypertensive therapy but rarely receive concomitant statin therapy. Despite the potential to significantly reduce cardiovascular risk, over half of these patients do not receive cholesterol-lowering statins during their first year of treatment.
A new salt substitute with high potassium content significantly reduced blood pressure in rural Northern China, comparable to single-drug therapy. The study suggests that a population-wide switch to this salt substitute could prevent hundreds of thousands of serious vascular events annually.
A four-year study of 772 people with pre-hypertension found that early blood pressure treatment can postpone true hypertension by 15.6%. The study suggests that drug treatment interrupted blood-vessel processes that raise blood pressure, reducing the risk of heart disease and stroke.
A large randomized trial of over 8,300 women with low dietary calcium found that calcium supplements significantly reduced severe preeclampsia, gestational hypertension, and preterm delivery. Calcium supplementation also led to a lower risk of maternal and neonatal morbidity and mortality.
Researchers at Tohoku University discovered that adding rice bran to the diets of hypertensive rats lowered their systolic blood pressure by about 20 percent and inhibited angiotensin-1 converting enzyme. The study also found that rice bran significantly lowered levels of a marker called 8-OHdG, indicating reduced oxidative stress.
A new genetic test has been developed with a 78% accuracy in predicting individuals with low renin levels and salt sensitivity. The test is based on the number of variations found in salt-regulating genes, with more gene variants associated with bigger health problems.
Researchers examined treatment to maintain blood pressure in patients with orthostatic hypotension (OH) caused by a neurological disease. Pyridostigmine bromide, approved for other uses, showed promise in improving symptoms and reducing standing blood pressure. The medication was found to be beneficial with minimal side effects.
A new study has found that high blood pressure and kidney disease increase the risk for heart disease and stroke in older Americans. Patients with moderate chronic kidney disease had a 38% greater chance of developing heart disease than those with normal kidney function.
Researchers at Yale University have developed a novel proteomic analysis method to diagnose and monitor preeclampsia. The study identified specific fragments of albumin and serpina-1 as characteristic biomarkers for the condition.
A new public information campaign is launched to educate patients and doctors about the benefits of diuretics in controlling hypertension. The campaign aims to reduce serious illnesses such as heart attacks, strokes, and kidney failure by promoting lifestyle changes and diuretic use.
The ALLHAT study found that diuretics are more beneficial than calcium channel blockers, ACE inhibitors, or alpha blockers as initial treatment to lower blood pressure. Diuretics are well-tolerated with few side effects, making them a cost-effective choice for first-line blood pressure treatment.
A recent study by Dr. Luisa Borrell at Columbia University's Mailman School of Public Health reveals a racial disparity in hypertension among Hispanics, suggesting that being Black within this ethnic group is associated with the highest prevalence of high blood pressure. The research highlights the importance of addressing health inequ...
A recent study suggests that U.S. Hispanics have lower rates of high blood pressure than non-Hispanics, but this advantage disappears when race is accounted for. The research found that black Hispanics exhibit the highest prevalence of hypertension, regardless of their ethnicity.
A study of 76 men found that those taking impotency drugs like Viagra and Cialis were more likely to develop optic nerve damage. Patients with pre-existing heart disease or high blood pressure also showed a higher risk.
A four-year study of designer rats with high blood pressure and healthy counterparts has identified candidate genes that may contribute to cardiovascular disease. The online database TREX is now available to researchers worldwide, offering an unprecedented amount of data to mine.
A study analyzing data from the INTERMAP study found a significant association between higher vegetable protein intake and lower blood pressure levels. The researchers suggest that amino acids in vegetable proteins may play a role in this effect, and other dietary components like magnesium may also contribute.
Exercise has been shown to delay the onset of heart failure and improve survivability in rats with spontaneously hypertensive heart failure. The study also found that low-intensity exercise suppressed many physiological changes associated with CHF, including alterations in myosin heavy chain isoform expression and cardiac cell morphology.
Researchers found that uncontrolled high blood pressure significantly worsens verbal fluency and short-term memory in older men. The study suggests that controlling hypertension can help mitigate age-related cognitive declines and may even be beneficial for cognition.
A recent study published in the American Journal of Clinical Nutrition found that consuming skimmed milk products can significantly reduce the risk of hypertension by 50%. The research, which followed 6,000 people over two years, revealed no association between whole milk consumption and hypertension risk. These findings contribute to ...
A study of 5,700 patients found that carriers of a specific genetic variation had a 43% higher risk of death, heart attack, or stroke. The research aims to tailor drugs to individual patients based on their genetic makeup, potentially leading to safer and more effective treatments.
A new study from Johns Hopkins Medicine finds that alagebrium reduces stiffening in arteries by 37% and improves endothelial function by 102%. The drug works by breaking down advanced glycation endproducts, which contribute to arterial aging. The results suggest a potential new therapy for reducing cardiovascular disease in the elderly.