Research on high blood pressure and its consequences. Covers heart-failure prediction, kidney-disease models, AI detection, and cardiovascular risk.
Dr. Watts' research suggests that serotonin may play a role in lowering blood pressure, contradicting previous findings that it causes constriction. She hopes to resolve the 'serotonin puzzle' with her lecture and gather input from fellow physiologists.
A meta-analysis of previously published studies found that dieting and medication can significantly lower blood pressure in patients with hypertension. Weight loss interventions involving orlistat resulted in greater reductions in both body weight and blood pressure compared to usual care or placebo groups.
Researchers found that men with one or two hypertensive parents had higher average blood pressure and a greater risk of developing hypertension. Early-onset hypertension in both parents was associated with a significantly higher risk of developing hypertension by age 35.
A meta-analysis conducted at the University of Kentucky found Transcendental Meditation to be an effective treatment for controlling high blood pressure, with significant reductions in systolic and diastolic blood pressure.
A study published in Archives of Ophthalmology found that black patients with diagnosed and treated glaucoma have a higher risk of cardiovascular death. The research suggests that this increased risk may be due to the use of certain medications used to treat glaucoma.
A large cohort study found that male smokers who consumed more magnesium had a 15% lower risk of cerebral infarction, a type of stroke. The association was strongest in men younger than 60 years.
A study published in Neurology found that black patients are 3.5 times more likely to experience severe vision loss and nearly five times more likely to become legally blind compared to non-black patients. This increased risk may be attributed to other factors such as higher body mass index, low blood iron, and higher brain pressures.
A large-scale study published in the American Heart Association rapid access journal report found that cigarette smoking is a significant predictor of stroke in Chinese men. Researchers analyzed data from over 170,000 participants and found that smokers were 2-3 times more likely to suffer an ischemic stroke compared to never-smokers.
A phase IIa trial found that vaccination against angiotensin II reduced mean daytime blood pressure by -9.0/-4.0 mm Hg in patients with mild-to-moderate hypertension. The authors propose a few injections per year as an alternative to traditional medication, potentially improving treatment adherence.
A new study finds that smoking and high blood pressure have a synergistic effect, increasing the risk of hemorrhagic stroke. Quitting smoking and lowering blood pressure can significantly reduce this risk, as seen in a cohort of over 563,000 participants.
Researchers found an association between leptin resistance and high blood pressure in people with Bardet-Biedl syndrome, a rare genetic disorder. Leptin resistance disrupts brain signals that regulate appetite and metabolism.
A new study published in PLoS Medicine shows that individuals who drink on a regular basis have a higher systolic blood pressure due to the ALDH2 gene variant. This association indicates that alcohol intake has an effect on blood pressure, particularly for Japanese men.
Researchers studied 317 healthy teens aged 15-18 and found higher rates of albumin in the urine of black teens compared to their white counterparts, even with normal blood pressure. This suggests that kidney damage is apparent before hypertension develops in high-risk youths.
Researchers found that older Americans with high stroke risk, but without a history of stroke, experience accelerated cognitive decline. The study, conducted by the American Heart Association, analyzed data from over 17,000 participants and found that those at high risk declined twice as fast as those considered low-risk.
A new study suggests that drinking fat-free milk may offer protection against hypertension in women. Women who consumed more low-fat milk and had diets higher in calcium and vitamin D from foods tended to have a lower risk for developing high blood pressure.
Researchers have discovered a link between viral infection, particularly from the herpes group, and pregnancy-induced hypertensive disease and pre-term birth. The study found viral nucleic acid in heel-prick blood samples of 1326 newborn babies, including over 400 with cerebral palsy.
Researchers monitored 140 sleeping volunteers near London Heathrow and three major European airports, finding that aircraft noise increased systolic blood pressure by an average of 6.2 mmHg and diastolic blood pressure by 7.4 mmHg. The study's findings highlight the need to reduce night-time aircraft noise levels to protect public health.
Research finds that men who exercised regularly and had a healthy lifestyle were more likely to live to age 90. In contrast, those with smoking, obesity, or hypertension had reduced longevity. Additionally, centenarians with certain health conditions developed them at an older age tended to have better mental and physical function.
A recent study found that a small proportion of individuals with hypertension eat diets aligned with government guidelines, while many others consume unhealthy patterns. The Dietary Approaches to Stop Hypertension (DASH) trial showed that a balanced diet high in fruits and vegetables can significantly lower blood pressure.
A study of pregnant women with preeclampsia found elevated levels of a peptide that raises blood pressure, potentially explaining its development. The researchers hope the findings may lead to treatment for preeclampsia by targeting specific tissues.
Researchers are exploring whether electronic personal health records enhance patient involvement in managing their hypertension. A year-long study of 720 patients will compare outcomes for those using the new system with standard treatment.
A study of 7,374 participants found that those taking calcium channel blockers for high blood pressure had a lower risk of developing Parkinson's disease. The medication was shown to cut the risk by 23% compared to non-users, but not other high blood pressure medications.
A daily dose of beetroot juice can significantly reduce blood pressure, according to a study published in the American Heart Association journal Hypertension. The research reveals that dietary nitrate, found in beetroot juice, leads to decreased blood pressure by converting into nitrite and then nitric oxide.
A large-scale drug comparison trial involving 23,077 people with both high blood pressure and metabolic syndrome found that diuretics significantly reduced the risk of heart disease. Diuretics were particularly effective in reducing cardiovascular disease in black patients, who have a higher incidence of hypertension.
A study found that diuretics offer no advantages over other hypertension medications for treating metabolic syndrome, particularly in black patients. Diuretics were shown to be more beneficial than calcium channel blockers, ACE inhibitors, and alpha-blockers in preventing cardiovascular disease and kidney problems.
A new study has discovered a link between gene variations and the effectiveness of blood pressure medications. Patients with certain gene variations experienced varying results with different types of medication, suggesting that tailoring treatment to an individual's genotype may lead to more favorable outcomes.
A systematic review found sorafenib significantly increases the risk of developing hypertension, particularly high-grade hypertension. Patients receiving sorafenib require close monitoring and effective management to prevent cardiovascular complications.
Researchers at Ohio State University identified a genetic link between the profilin 1 gene and increased risk of high blood pressure in older adults. The gene affects vascular remodeling, which can lead to structural and functional changes in blood vessels, ultimately causing hypertension.
Dr. Joseph Ravenell receives $416,558 grant to study physician inertia and its impact on hypertension treatment in African-American men. The award supports his research to benefit underserved patients and decrease health disparities.
Bystolic is a once-daily medication that can be used as monotherapy or in combination with other treatments to reduce blood pressure. It selectively blocks the effects of adrenaline at the heart and vasodilates blood vessels, offering a low incidence of traditional beta blocker side effects.
Patients with subclinical Cushing syndrome experience significant clinical improvement after adrenalectomy, including improved diabetes and hypertension. The study highlights the benefits of surgery for some patients with large adrenal tumors who suffer from hormonal disorders.
Research findings suggest a significant association between high blood pressure and the development of mild cognitive impairment. Approximately 9.9 out of every 1,000 elderly individuals without dementia develop this condition yearly, with 10-12% progressing to Alzheimer's disease each year.
Researchers found that good continuous positive airway pressure (CPAP) treatment compliance significantly reduced blood pressure in patients with obstructive sleep apnea. Additionally, oral prednisolone was shown to be equally effective as intravenous administration for treating COPD exacerbations, with the latter being preferred due t...
A study found that nearly three-fourths of American adults with conditions increasing cardiovascular disease risk also have hypertension. Despite treatment, only one-third to one-half of these individuals reach their blood pressure goals.
A new study found that hypertension significantly reduces cerebral blood flow in adults with Alzheimer's disease, increasing its vulnerability to the effects of the disease. Good vascular health is crucial for brain health, and detecting and treating hypertension can help prevent or slow cognitive decline.
Researchers have developed a new drug called nitrosyl-cobinamide, a direct NO-releasing agent that could potentially treat hypertension and heart disease. The compound binds tightly to nitric oxide, forming a reversible NO donor, which may offer a safer alternative to existing treatments.
Granger received the award for his research on preeclampsia, a pregnancy-related disease affecting nearly 5-7 percent of U.S. pregnancies. He has also improved graduate education at the University of Mississippi Medical Center.
A new study finds that 92% of older adults with diabetes have at least one other major chronic condition, and nearly half have three or more. The severity and type of co-existing condition matter, decreasing patients' ability to manage their diabetes.
A recent study published in the British Medical Journal found that adults insured through Mexico's Seguro Popular program are more likely to receive antihypertensive treatment and have their blood pressure controlled than those without health insurance. Insured individuals had a 50% higher odds of receiving antihypertensive treatment, ...
Mayo Clinic researchers will study renal vascular disease caused by atherosclerosis to find new ways to diagnose and treat the condition. The study aims to develop novel imaging tools to predict, detect, and evaluate the disease, with the goal of preventing renal deterioration.
The estimated prevalence of chronic kidney disease in US adults has increased from 10% to 13%, driven by rising diabetes and hypertension rates. The prevalence of earlier stages of CKD accounts for most individuals with the condition, highlighting the need for cardiovascular risk factor management.
A new vaccine targeting angiotensin II has shown promising results in reducing blood pressure in a small study. The vaccine produced strong antibody responses and significantly lowered systolic and diastolic blood pressures in patients with mild-to-moderate high blood pressure.
Researchers found that people with high blood pressure or atrial fibrillation progress more rapidly with Alzheimer's disease. Treating these conditions may also slow memory loss in AD patients.
A study published in Neurology found that people with high blood pressure and chest pains lose their memories faster than those without these conditions. Vascular factors such as high blood pressure and irregular heartbeats were associated with a more rapid decline in cognitive tests.
A simplified step-care protocol for treating high blood pressure was more effective than guidelines-based practice in helping people reduce their blood pressure. The Simplified Treatment Intervention to Control Hypertension (STITCH) trial found that 65% of patients reached the target blood pressure level with STITCH-care, compared to 5...
A five-year study of electronic health records from 15 VA hospitals found significant variations in high blood pressure return-to-normal rates between winter and summer. The average difference was 7.76 percent, suggesting that seasonal factors such as weight gain and exercise may influence blood pressure.
Dr. Paul K. Whelton has been awarded the American Heart Association's Population Research Prize for his pioneering work in documenting the burden of cardiovascular diseases. His research has provided vital data on hypertension and its impact on populations worldwide.
Researchers found that PAD prevalence increased from 3.7% to 4.6% among asymptomatic adults aged 40-70 between 1999-2004. The study suggests a link between rising obesity, diabetes, hypertension, and smoking rates, emphasizing the importance of screening for PAD in asymptomatic patients.
Kenneth E. Bernstein identified key components of blood pressure control and was awarded the American Heart Association's Basic Research Prize for his work. His discoveries have led to a major approach in treating hypertension, coronary artery disease, heart failure, and diabetic nephropathy.
A large-scale study has found no significant increase in cardiovascular risk for living kidney donors, but higher rates of high blood pressure were detected. The study analyzed data from 1,278 patients and compared them to 6,369 healthy adults.
A study by UNC researchers concludes that people over 60 with high blood pressure are less likely to receive lifestyle modification advice from their doctors compared to younger groups. Despite this, most patients remember receiving some type of advice on making healthier choices to lower their blood pressure.
Researchers at OHSU have identified the WNK kinase protein complex as a master switch that regulates blood pressure. The study reveals how this complex modulates salt and potassium balance in the kidney, raising or lowering blood pressure depending on its functioning.
A study published in the American Journal of Preventive Medicine found a positive correlation between TV time and the severity of obesity in children. The researchers determined that children watching more than 2 hours of TV per day were 2.5-3.3 times more likely to have hypertension compared to those watching less than 2 hours.
Researchers found that African-American college students reported poorer sleep quality, slept less time, and took longer to fall asleep compared to whites. These findings suggest that ethnic differences in sleep quality may be linked to higher blood pressure risk and 'blood pressure dipping',
The REVEAL Registry aims to provide reliable information on PAH demographics, clinical course, and management. Researchers found that most patients experience a significant delay between symptom onset and diagnosis, with up to 3-year delays in some cases.
Men who consume more whole grain breakfast cereals have a lower risk of heart failure. The study found that participants with higher cereal intake had a significantly reduced risk of heart failure compared to those who didn't eat any cereal.
Obese Medicaid patients undergoing Roux-en-Y gastric bypass surgery were more likely to return to work, with 37% working after surgery compared to 6% of non-surgical controls. Resolution of comorbid conditions post-surgery was a key factor in return to work.
Researchers have found that ultra-low-dose aspirin can normalize platelet-endothelial cell alterations and bleeding time in rats with portal hypertension. This effect is mediated by Cyclooxygenase 2 inhibition, a finding that could have implications for treating this debilitating condition.
A study of 38,000 female health professionals found that women with hypertension have a three-fold risk of developing type 2 diabetes compared to those with optimal blood pressure levels. Obesity is also a strong and independent risk factor for the development of type 2 diabetes.
Researchers found that a combined treatment with rapamycin and Gleevec significantly reduced splanchnic neovascularization and portal pressure in rats with established portal hypertension. The combination treatment was more effective than using either drug alone, suggesting a potential new approach for treating human patients.