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Science News for September 4, 2007


Income inequality associated with overnourishment and undernourishment in India

A study by Harvard T.H. Chan School of Public Health found that India's high income inequality leads to a double-disease burden, with poor individuals facing undernutrition and affluent individuals experiencing overnutrition. The risk of both conditions increases with widening income gaps between the rich and the poor.

SourceHarvard T.H. Chan School of Public Health·JournalJournal of Epidemiology and Community Health·DateSep 4, 2007

JCI table of contents: Sept. 4, 2007

Researchers found that immunosuppressive drugs suppress beta-cell regeneration in diabetic mice, raising questions about the potential of successful regenerative islet transplantation. Meanwhile, a new study demonstrated that eIF4E-specific antisense oligonucleotides reduce tumor growth without causing damage to normal tissues.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 4, 2007

Better communicators make better doctors

A study by McGill University found that physicians who score poorly on patient-physician communication skills exams are more likely to generate patient complaints. The exam's results prove its value in predicting patient complaints and could be used earlier in medical school admissions.

SourceMcGill University·JournalJAMA·DateSep 4, 2007

Unmasking DNA

Researchers Adam Woolley and Héctor Becerril develop 'DNA shadow nanolithography' using DNA molecules as nanostencils. The technique enables the creation of high-aspect-ratio trenches and nanowires with precise control over dimensions.

SourceWiley·JournalSmall·DateSep 4, 2007

Genetic background to severe urinary tract infections

Scientists at Lund University have found a genetic basis for severe urinary tract infections, suggesting a gene that regulates the immune system may be used as a risk marker. This discovery could enable early detection of susceptible individuals, potentially reducing unnecessary examinations and treatment.

SourcePLOS·JournalPLOS ONE·DateSep 4, 2007

3-D fruit fly images to benefit brain research

Researchers have created 3D images of fruit fly brains using optical projection tomography, shedding light on genetic research into Alzheimer's and other human diseases. The images allow scientists to visualize gene expression patterns and gain insights into the human brain.

SourcePLOS·JournalPLOS ONE·DateSep 4, 2007

University of Alberta researchers find new cause of blindness

Researchers at the University of Alberta have found a new cause of blindness linked to a gene that regulates pH levels in the retina. The study suggests that targeting this process could lead to potential treatments for previously unknown causes of blindness, including hereditary vitreoretinal degenerations.

SourcePLOS·JournalPLOS ONE·DateSep 4, 2007

Study examines performance-based pay for teachers

A recent study by economists at the University of Missouri-Columbia and Vanderbilt University found that linking teacher pay to student achievement results in improved student outcomes. The researchers advocate for school districts to explore performance-based systems as a potential solution to increase teacher effectiveness.

SourceUniversity of Missouri-Columbia·JournalJournal of Policy Analysis and Management·DateSep 4, 2007

Burning extra calories with a 'futile protein cycle'

Researchers found that mice with a disrupted enzyme involved in protein metabolism became slimmer despite eating more food, showing improved glucose and insulin tolerance. The study suggests a new potential weight-loss therapy by manipulating protein turnover through pharmacological means.

SourceCell Press·JournalCell Metabolism·DateSep 4, 2007

A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols

Researchers have developed a protocol for generating mice with squamous cell carcinoma, allowing them to study the disease in a controlled environment. The method involves injecting mice with DMBA and TPA, leading to tumor formation and enabling scientists to examine the role of the immune system in susceptibility to skin cancer.

SourceCold Spring Harbor Laboratory·JournalCold Spring Harbor Protocols·DateSep 4, 2007