Articles tagged with Hypertension
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A study of pregnant women with preeclampsia found elevated levels of a peptide that raises blood pressure, potentially explaining its development. The researchers hope the findings may lead to treatment for preeclampsia by targeting specific tissues.
A study of 7,374 participants found that those taking calcium channel blockers for high blood pressure had a lower risk of developing Parkinson's disease. The medication was shown to cut the risk by 23% compared to non-users, but not other high blood pressure medications.
Researchers are exploring whether electronic personal health records enhance patient involvement in managing their hypertension. A year-long study of 720 patients will compare outcomes for those using the new system with standard treatment.
A daily dose of beetroot juice can significantly reduce blood pressure, according to a study published in the American Heart Association journal Hypertension. The research reveals that dietary nitrate, found in beetroot juice, leads to decreased blood pressure by converting into nitrite and then nitric oxide.
A large-scale drug comparison trial involving 23,077 people with both high blood pressure and metabolic syndrome found that diuretics significantly reduced the risk of heart disease. Diuretics were particularly effective in reducing cardiovascular disease in black patients, who have a higher incidence of hypertension.
A study found that diuretics offer no advantages over other hypertension medications for treating metabolic syndrome, particularly in black patients. Diuretics were shown to be more beneficial than calcium channel blockers, ACE inhibitors, and alpha-blockers in preventing cardiovascular disease and kidney problems.
A new study has discovered a link between gene variations and the effectiveness of blood pressure medications. Patients with certain gene variations experienced varying results with different types of medication, suggesting that tailoring treatment to an individual's genotype may lead to more favorable outcomes.
A systematic review found sorafenib significantly increases the risk of developing hypertension, particularly high-grade hypertension. Patients receiving sorafenib require close monitoring and effective management to prevent cardiovascular complications.
Researchers at Ohio State University identified a genetic link between the profilin 1 gene and increased risk of high blood pressure in older adults. The gene affects vascular remodeling, which can lead to structural and functional changes in blood vessels, ultimately causing hypertension.
Dr. Joseph Ravenell receives $416,558 grant to study physician inertia and its impact on hypertension treatment in African-American men. The award supports his research to benefit underserved patients and decrease health disparities.
Bystolic is a once-daily medication that can be used as monotherapy or in combination with other treatments to reduce blood pressure. It selectively blocks the effects of adrenaline at the heart and vasodilates blood vessels, offering a low incidence of traditional beta blocker side effects.
Patients with subclinical Cushing syndrome experience significant clinical improvement after adrenalectomy, including improved diabetes and hypertension. The study highlights the benefits of surgery for some patients with large adrenal tumors who suffer from hormonal disorders.
Research findings suggest a significant association between high blood pressure and the development of mild cognitive impairment. Approximately 9.9 out of every 1,000 elderly individuals without dementia develop this condition yearly, with 10-12% progressing to Alzheimer's disease each year.
Researchers found that good continuous positive airway pressure (CPAP) treatment compliance significantly reduced blood pressure in patients with obstructive sleep apnea. Additionally, oral prednisolone was shown to be equally effective as intravenous administration for treating COPD exacerbations, with the latter being preferred due t...
A study found that nearly three-fourths of American adults with conditions increasing cardiovascular disease risk also have hypertension. Despite treatment, only one-third to one-half of these individuals reach their blood pressure goals.
A new study found that hypertension significantly reduces cerebral blood flow in adults with Alzheimer's disease, increasing its vulnerability to the effects of the disease. Good vascular health is crucial for brain health, and detecting and treating hypertension can help prevent or slow cognitive decline.
Researchers have developed a new drug called nitrosyl-cobinamide, a direct NO-releasing agent that could potentially treat hypertension and heart disease. The compound binds tightly to nitric oxide, forming a reversible NO donor, which may offer a safer alternative to existing treatments.
Granger received the award for his research on preeclampsia, a pregnancy-related disease affecting nearly 5-7 percent of U.S. pregnancies. He has also improved graduate education at the University of Mississippi Medical Center.
A new study finds that 92% of older adults with diabetes have at least one other major chronic condition, and nearly half have three or more. The severity and type of co-existing condition matter, decreasing patients' ability to manage their diabetes.
A recent study published in the British Medical Journal found that adults insured through Mexico's Seguro Popular program are more likely to receive antihypertensive treatment and have their blood pressure controlled than those without health insurance. Insured individuals had a 50% higher odds of receiving antihypertensive treatment, ...
Mayo Clinic researchers will study renal vascular disease caused by atherosclerosis to find new ways to diagnose and treat the condition. The study aims to develop novel imaging tools to predict, detect, and evaluate the disease, with the goal of preventing renal deterioration.
A new vaccine targeting angiotensin II has shown promising results in reducing blood pressure in a small study. The vaccine produced strong antibody responses and significantly lowered systolic and diastolic blood pressures in patients with mild-to-moderate high blood pressure.
The estimated prevalence of chronic kidney disease in US adults has increased from 10% to 13%, driven by rising diabetes and hypertension rates. The prevalence of earlier stages of CKD accounts for most individuals with the condition, highlighting the need for cardiovascular risk factor management.
A five-year study of electronic health records from 15 VA hospitals found significant variations in high blood pressure return-to-normal rates between winter and summer. The average difference was 7.76 percent, suggesting that seasonal factors such as weight gain and exercise may influence blood pressure.
Researchers found that people with high blood pressure or atrial fibrillation progress more rapidly with Alzheimer's disease. Treating these conditions may also slow memory loss in AD patients.
A study published in Neurology found that people with high blood pressure and chest pains lose their memories faster than those without these conditions. Vascular factors such as high blood pressure and irregular heartbeats were associated with a more rapid decline in cognitive tests.
A simplified step-care protocol for treating high blood pressure was more effective than guidelines-based practice in helping people reduce their blood pressure. The Simplified Treatment Intervention to Control Hypertension (STITCH) trial found that 65% of patients reached the target blood pressure level with STITCH-care, compared to 5...
Kenneth E. Bernstein identified key components of blood pressure control and was awarded the American Heart Association's Basic Research Prize for his work. His discoveries have led to a major approach in treating hypertension, coronary artery disease, heart failure, and diabetic nephropathy.
Dr. Paul K. Whelton has been awarded the American Heart Association's Population Research Prize for his pioneering work in documenting the burden of cardiovascular diseases. His research has provided vital data on hypertension and its impact on populations worldwide.
Researchers found that PAD prevalence increased from 3.7% to 4.6% among asymptomatic adults aged 40-70 between 1999-2004. The study suggests a link between rising obesity, diabetes, hypertension, and smoking rates, emphasizing the importance of screening for PAD in asymptomatic patients.
A large-scale study has found no significant increase in cardiovascular risk for living kidney donors, but higher rates of high blood pressure were detected. The study analyzed data from 1,278 patients and compared them to 6,369 healthy adults.
A study by UNC researchers concludes that people over 60 with high blood pressure are less likely to receive lifestyle modification advice from their doctors compared to younger groups. Despite this, most patients remember receiving some type of advice on making healthier choices to lower their blood pressure.
Researchers at OHSU have identified the WNK kinase protein complex as a master switch that regulates blood pressure. The study reveals how this complex modulates salt and potassium balance in the kidney, raising or lowering blood pressure depending on its functioning.
A study published in the American Journal of Preventive Medicine found a positive correlation between TV time and the severity of obesity in children. The researchers determined that children watching more than 2 hours of TV per day were 2.5-3.3 times more likely to have hypertension compared to those watching less than 2 hours.
Researchers found that African-American college students reported poorer sleep quality, slept less time, and took longer to fall asleep compared to whites. These findings suggest that ethnic differences in sleep quality may be linked to higher blood pressure risk and 'blood pressure dipping',
The REVEAL Registry aims to provide reliable information on PAH demographics, clinical course, and management. Researchers found that most patients experience a significant delay between symptom onset and diagnosis, with up to 3-year delays in some cases.
Men who consume more whole grain breakfast cereals have a lower risk of heart failure. The study found that participants with higher cereal intake had a significantly reduced risk of heart failure compared to those who didn't eat any cereal.
Obese Medicaid patients undergoing Roux-en-Y gastric bypass surgery were more likely to return to work, with 37% working after surgery compared to 6% of non-surgical controls. Resolution of comorbid conditions post-surgery was a key factor in return to work.
Researchers have found that ultra-low-dose aspirin can normalize platelet-endothelial cell alterations and bleeding time in rats with portal hypertension. This effect is mediated by Cyclooxygenase 2 inhibition, a finding that could have implications for treating this debilitating condition.
A study of 38,000 female health professionals found that women with hypertension have a three-fold risk of developing type 2 diabetes compared to those with optimal blood pressure levels. Obesity is also a strong and independent risk factor for the development of type 2 diabetes.
Researchers found that a combined treatment with rapamycin and Gleevec significantly reduced splanchnic neovascularization and portal pressure in rats with established portal hypertension. The combination treatment was more effective than using either drug alone, suggesting a potential new approach for treating human patients.
A study of California adults with high blood pressure found that nearly half do not take medication, despite seeing a doctor. Regular doctor visits significantly improve medication adherence in those who do take pills.
Researchers found that 50% of overweight, hypertensive adults achieved normal body weight and blood pressure after six months of treatment with a reduced-calorie diet. This suggests that blood pressure may be secondary to body weight rather than essential hypertension in these patients.
Researchers found that people with high blood pressure require more coordinated brain blood flow to perform memory tasks, even after treatment. This increased coordination was observed in the four areas of the brain involved in memory: thalamus, posterior parietal, prefrontal area, and hippocampus.
A study by USC researchers found that a storyline on ER about teen obesity and healthy eating habits positively impacted viewers' attitudes and behaviors, with men showing the strongest effects. The study highlights the potential of entertainment television as a medium for health communication.
Researchers identified single nucleotide polymorphisms (SNPs) in the adducin 2 gene that influence blood pressure regulation among people with hypertension. The study found associations between SNPs and differential responses to different antihypertensive drugs, highlighting potential for tailored treatment regimens.
Studies have shown that hypertension awareness, treatment, and control are lower among Hispanics compared to non-Hispanics. However, a recent study found that Hispanic men and women responded as well or better than non-Hispanics when treated aggressively with medication. At four years, blood pressure was controlled in 72% of Hispanic w...
A new study published in Annals of Internal Medicine found that preventing or reducing left ventricular hypertrophy (LVH) decreases the risk of heart failure in high-blood-pressure patients. The study, led by Dr. Peter Okin, demonstrated a significant reduction in heart failure risk among patients with reduced LVH levels.
A meta-analysis of 21 studies found that being moderately overweight increases heart disease risk by 32%, while obesity raises it by 81%. Excess weight is linked to increased blood pressure and cholesterol levels, accounting for 45% of the increased risk.
Researchers found that N-acetylcysteine can form a molecule that tricks the body into thinking it has an oxygen shortage, leading to pulmonary arterial hypertension. The discovery opens up new possibilities for treating PAH and highlights the need to monitor patients using NAC.
A study by Temple University researcher Kathleen Black identifies warning signs of pregnancy-induced hypertension, including increased stress levels, which can indicate worsening conditions. Women experiencing headaches, dizziness, frequent vomiting and malaise should call their physician immediately.
A study found that only about one in four children with hypertension had been previously diagnosed, highlighting the need for improved diagnosis and treatment strategies
Researchers identified EP1 as a key factor in blood pressure regulation and found that inhibiting it can reduce hypertension. Targeting this receptor subtype may be a viable approach to treating high blood pressure.
A recent study found that exercise did not lower aldosterone levels in African Americans, a hormone linked to hypertension. Despite this, researchers believe exercise still has potential benefits for reducing blood pressure. The study's findings highlight the complexity of understanding hypertension in African Americans.
The Lancet Editorial warns that hypertension's increasing burden will largely stem from poor lifestyles, with a staggering 90% risk of developing the condition in developed countries. Effective treatments exist, yet many patients misbelieve they can 'cure' hypertension and stop medication when their blood pressure falls.
Researchers found that impaired energy production in heart muscle may underlie heart failure in some hypertensive patients. A protein called estrogen-related receptor alpha (ERR alpha) helps the heart keep up with energy-draining conditions like high blood pressure.
Researchers found genomic determinants underlying alcohol and tobacco use on chromosomes 1, 3, and 4. A common locus for both was discovered on chromosome 1, with a linked area for smoking also present. The study suggests sex-specific genetic factors may contribute to the observed sex differences in alcohol and tobacco use rates.
Researchers identified distinct genetic factors for blood pressure regulation in males and females, shedding light on gender-based disparities in cardiovascular health. The study's findings suggest that genetic diagnostic and therapeutic indices for hypertension must consider gender differences.
Researchers have found that grape seed polyphenols reduce salt-sensitive hypertension in young rats, while soy polyphenols protect against hypertension in estrogen-depleted/ovariectomized rats. Kudzu root extract also blunts blood pressure rise and improves glucose tolerance in animal models of insulin resistance.
Researchers found that less than a third of treatment guidelines are based on high-quality evidence, highlighting the need for transparent grading systems. The study concludes that clinicians should be aware of this limitation and apply guideline recommendations appropriately to individual patients.