Research on high blood pressure and its consequences. Covers heart-failure prediction, kidney-disease models, AI detection, and cardiovascular risk.
A protein long thought secondary to stressors like hypertension is actually a primary regulator according to researchers. Knocking out GSK-3alpha causes significant hypertrophy in mice models. The findings also suggest GSK-3alpha as a positive regulator of the beta-adrenergic system, potentially helping failing hearts pump better.
A new study from Johns Hopkins Medicine suggests that young athletes should undergo both EKG and echocardiogram screenings to detect early signs of life-threatening heart defects. Abnormal findings were discovered in 36 athletes, highlighting the importance of comprehensive screening programs.
A study found that one-third of children with CKD have masked hypertension, which increases the risk of left ventricular hypertrophy and heart disease. Children with masked hypertension are four times more likely to develop LVH, highlighting the need for regular blood pressure monitoring outside the clinic.
A prospective study found obesity and hypertension to be independent predictors of left atrial enlargement, increasing the risk of atrial fibrillation, stroke, and death. Obesity was associated with greater increases in left atrial volume and incidence of LAE compared to hypertension.
A special issue of a medical journal examines Latino health disparities, including chronic diseases like hypertension and diabetes. It also highlights the lack of access to primary care services and patient-centered medical homes among Latinos.
Researchers at Thomas Jefferson University have received $3.9 million in Challenge grant funds to tackle specific scientific and health research challenges in biomedical and behavioral sciences. Drs. Flemming Forsberg, Laura N. Gitlin, Maurizio Pacifici, and Scott Waldman will study portal venous pressure, depression treatment, Heredit...
Research suggests that high blood pressure and inflammatory markers are more prevalent in middle age among individuals with a family history of Alzheimer's disease. The study also found that these risk factors cluster within families, highlighting the potential for early interventions to prevent late-onset Alzheimer's disease.
Researchers at the University of Warwick have identified central obesity, high blood pressure, and high blood sugar as the most dangerous combination of health factors for developing metabolic syndrome. This combination can increase the risk of heart attack by doubling it and mortality rates by three times.
A diet high in fructose increases the risk of developing high blood pressure. Studies found that consuming more than 74 grams per day of fructose led to a higher risk of hypertension, with significant associations seen across various blood pressure levels.
The Systolic Blood Pressure Intervention Trial (SPRINT) aims to determine whether maintaining blood pressure levels below current recommendations reduces cardiovascular and kidney disease risk. The nine-year trial will enroll over 7,500 participants aged 55+ with high systolic blood pressure.
A study by University of Rochester Medical Center evaluates the cost effectiveness of an experimental blood pressure device called Rheos. The research suggests that Rheos can be a cost-effective treatment for individuals with drug-resistant hypertension, especially those with extremely high blood pressure or diabetes.
Research found a higher incidence of chronic rhinosinusitis among patients with other chronic diseases, particularly asthma. The study suggests that some chronic diseases may share common mechanisms of how they arise or progress, highlighting the need for further investigation into the relationship between CRS and other conditions.
Research found that premenopausal women with vitamin D deficiency were three times more likely to develop systolic hypertension 15 years later. Vitamin D has a well-established role in bone health, and deficiency may also increase cancer risk and immune function problems.
A five-year study at Penn State will analyze hypertension in humans and laboratory conditions, shedding light on potential therapeutic strategies for people with essential hypertension. The study aims to understand how hypertension affects the body's cardiovascular system and its impact on individuals.
Excessive sodium consumption linked to high blood pressure, cardiovascular disease, and various cancers. A population-wide reduction in sodium intake could prevent significant cardiovascular events.
A new endothelin type A antagonist, darusentan, provides significant reduction in blood pressure for patients with treatment-resistant hypertension. The study shows that darusentan is generally well-tolerated, but fluid retention is a main adverse effect.
A new study estimates that reducing Americans' average intake of sodium to recommended levels could save the nation $18 billion annually in avoided health care costs. Meeting national sodium guidelines could also eliminate 11 million cases of high blood pressure nationally and extend thousands of lives each year.
Research suggests that living close to noisy roads increases the risk of developing hypertension and cardiovascular diseases. The study found modest exposure effects at lower noise levels, but more marked effects among younger and middle-aged populations.
A new study by the University of Florida combines socio-cultural and genetic data to reveal health disparities between different groups. The research suggests that social classification is a better predictor of disease status than genetic ancestry.
The KYOTO HEART Study found that valsartan significantly reduced the incidence of cardiovascular events, including angina pectoris and stroke/TIA, in Japanese hypertensive patients. The study showed a lower rate of primary endpoints in the valsartan arm compared to non-ARB conventional therapies.
A study led by a University of North Carolina researcher found that black patients with high blood pressure experience poorer communication with their doctors compared to white patients. The results showed that black patients had shorter office visits, less biomedical and psychosocial exchange, and less rapport building with their doct...
Researchers at Medical College of Georgia have found that deleting or mutating the gene PTP1B puts mice at risk for hypertension by interfering with an endogenous mechanism that should prevent it. The study suggests that PTP1B is a vulnerability gene, and its status could help identify individuals at risk for hypertension.
Researchers found that lowering heart rate with Beta-blockers can increase central aortic pressures in older individuals with high blood pressure, leading to reduced stroke prevention. The study suggests that alternative treatments may be more effective in this population.
Research published by the American Academy of Neurology links high blood pressure to cognitive impairment in people over 45. The study found that those with high diastolic blood pressure were more likely to experience memory and thinking problems.
A new study published in Obesity and Weight Management explores the link between obesity and erectile dysfunction, finding that excess weight increases the risk of ED due to atherosclerosis-related hypertension and hormonal changes. Research shows that weight loss and increased physical activity can improve symptoms.
New research finds that mortality among patients with idiopathic pulmonary arterial hypertension (IPAH) awaiting lung transplant has not decreased, despite implementation of a new allocation system. The study suggests that key prognostic indicators in IPAH are not adequately captured by the current LAS algorithm.
A recent study found carvedilol to be more effective in preventing variceal bleeding in cirrhotic patients compared to traditional treatment with variceal band ligation. The results showed that carvedilol reduced the risk of bleeding by 10% compared to VBL, while survival rates remained unchanged.
Researchers discovered a link between the anti-aging gene klotho and reduced high blood pressure, reversing kidney damage. The study shows that increasing klotho expression can lower blood pressure for at least 12 weeks and potentially prevent hypertension.
Researchers link high blood pressure to multiple sclerosis and suggest a safe, inexpensive drug lisinopril could be an effective treatment option. The study found that lisinopril controls blood pressure by blocking an enzyme that converts angiotensin's precursor into the active hormone.
Sumita B. Mitra's research on dental materials has restored millions of decayed teeth, while William E. Mickols and John Cadotte invented filters to desalinate seawater, providing fresh water for millions worldwide. Their innovations have led to significant breakthroughs in medicine and technology.
A DASH-style diet high in calcium, potassium, and magnesium, and low in sodium, was found to reduce the risk of kidney stone formation. Participants with higher scores on this dietary approach were between 40-45% less likely to develop kidney stones than those with lower scores.
A randomized trial found that targeting systolic blood pressure below 130 mmHg reduced left ventricular hypertrophy and clinical events, compared to a target of 140 mmHg. The study suggests that lowering systolic blood pressure in nondiabetic patients with hypertension may be beneficial.
A study published in The Lancet recommends inducing labor at 37 weeks for pregnant women with mild hypertensive disorders like gestational hypertension or mild pre-eclampsia. This approach reduces the risk of poor maternal outcomes, severe hypertension, HELLP syndrome, and caesarean sections.
A recent study found a strong association between sedentary behaviors like TV viewing and screen time, and elevated blood pressure in children. The researchers discovered that the risk was present even after adjusting for age, sex, height, and percentage of body fat.
A study published in Neurology found that people over 60 with high blood pressure are more likely to experience silent strokes. High blood pressure increases the risk by 60%, while white matter hyperintensities nearly double the likelihood of silent strokes.
Researchers found that centrally-acting ACE inhibitors, which cross the blood-brain barrier, may reduce inflammation and cognitive decline in patients with hypertension. These medications showed a significant association with lower rates of mental decline, particularly those taking drugs like captropril and lisinopril.
A study found that men who exercised regularly, drank moderately, didn't smoke, were not overweight, and followed a healthy diet had a lower lifetime risk of heart failure. The remaining lifetime risk was approximately 2-4% higher in men with hypertension compared to those without.
A study of 83,882 young adult women found that adopting six low-risk lifestyle factors was independently associated with lower risk of developing high blood pressure. The combination of normal BMI, daily vigorous exercise, DASH-style diet, modest alcohol intake, and folic acid supplementation resulted in an 80% lower risk of hypertension.
Research conducted by Yale University researchers found that women with preeclampsia in previous pregnancies are at higher risk of hypertension after pregnancy. Additionally, preterm delivery, preeclampsia, and low-birth weight tend to recur and increase the risk of complications in future pregnancies.
A study found five genetic variants associated with high systolic blood pressure in African-Americans, suggesting potential new treatments. The variants were located near genes that code for proteins involved in hypertension regulation, offering hope for improved prevention and treatment options.
A study found that transforming growth factor B1 (TGF-B1) is higher in blacks compared to whites, increasing the risk of hypertension and renal disease. Higher levels of TGF-B1 are also linked to body mass index and metabolic syndrome.
Researchers found that treatment intensification can improve blood pressure control in patients with varying levels of adherence, challenging a widely held assumption. The study's lead author recommends further studies to determine the most effective management strategy for uncontrolled hypertension and suboptimal adherence.
The Hypertension and Vascular Research Center at Wake Forest University School of Medicine has received a five-year, $6.643 million grant renewal from the National Heart, Lung and Blood Institute to continue studying hypertension and vascular disease.
A new science review highlights multiple health benefits of dairy foods, including improved bone health, lower blood pressure and a reduced risk of obesity. Dairy consumption is recommended for children and adults to meet daily nutrient needs.
Several biomarkers, including CRP and N-BNP, showed minimal added benefit in predicting cardiovascular events compared to conventional risk factors. The use of these biomarkers did not result in significant improvements in reclassification of individuals to new risk categories or changes in therapy.
New research warns of increasing rates of hypertension in Latin America, which poses a mounting threat to economies if not addressed. To combat this, policymakers and healthcare providers must work together to implement core policy changes, including detection, diagnosis, treatment, and control of high blood pressure.
Researchers from Boston University compared three measures of treatment intensity in hypertension care and found that the standard-based method predicts blood pressure control most effectively. The norm-based method was not a valid predictor of blood pressure control due to its non-linear relationship with systolic blood pressure.
Research found that obese children as young as 7 years old have abnormal blood markers predicting cardiovascular disease. Simple obesity can raise risk before the metabolic syndrome develops.
A new study from UC Davis found that retirement-aged Americans in lower-status occupations tend to have higher rates of hypertension. The researchers analyzed data from over 22,000 Americans and found a strong correlation between occupation and hypertension, suggesting that job history may be an important factor in understanding the de...
Middle-aged adults who sleep fewer hours are more likely to have high blood pressure and experience worsening blood pressure over time. The study, which included 578 adults, found that each hour of reduction in sleep duration was associated with a 37% increase in the odds of developing high blood pressure.
A study estimates that approximately 1.68 million US men over 50 years old suffer from dry eye disease, which increases with age and is associated with high blood pressure and certain medications. The prevalence of the condition rises significantly among older men, particularly those aged 75 and above.
Researchers found that high blood pressure, excessive weight, smoking, and diabetes significantly increased the size of the heart's left ventricle over short-term (4 years) and long-term (16 years) periods. These risk factors can be directly targeted for prevention and lowering may potentially lower heart failure burden.
Researchers found that doctors who treat patients with complex conditions provide high-quality care, even better than expected. This suggests that pay-for-performance initiatives may not penalize healthcare providers for caring for the sickest patients.
A study comparing NFL players' health to that of other healthy young men found lower incidence of impaired fasting glucose and similar prevalence of abnormal cholesterol levels. However, NFL players had a significantly higher prevalence of high blood pressure and prehypertension compared to the general population.
A simplified chart created by a pediatrician can help identify children with high blood pressure, improving diagnosis rates. The revised chart uses age and gender to determine abnormal readings, reducing the need for height percentile verification.
A new study suggests that cytomegalovirus (CMV) is a cause of high blood pressure, a leading risk factor for heart disease, stroke and kidney disease. The virus can lead to the development of atherosclerosis, or hardening of the arteries, when coupled with other risk factors.
A new study confirms the benefits of diuretic drugs in reducing the risk of heart failure and stroke in high blood pressure patients. The research, which analyzed data from multiple clinical trials, found that diuretics work as well or better than other medications in preventing major complications of hypertension.
A large study led by Beth Israel Deaconess Medical Center demonstrates that following the DASH diet significantly reduces women's risk of developing heart failure. The diet, high in plant foods and low in sugar and saturated fats, also lowers blood pressure.
Researchers found that increased O-GlcNAc levels damage blood vessels by reducing nitric oxide production, increasing blood pressure and vessel contraction. This discovery could lead to new treatments targeting the O-GlcNAc pathway.
A Swedish study found that women who followed the Dietary Approaches to Stop Hypertension (DASH) diet had a lower risk of heart failure. The study analyzed data from 36,019 women and found that those with higher DASH scores had half the rate of heart failure compared to those with lower scores.