Articles tagged with Hypertension
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at Medical College of Georgia have found that deleting or mutating the gene PTP1B puts mice at risk for hypertension by interfering with an endogenous mechanism that should prevent it. The study suggests that PTP1B is a vulnerability gene, and its status could help identify individuals at risk for hypertension.
The KYOTO HEART Study found that valsartan significantly reduced the incidence of cardiovascular events, including angina pectoris and stroke/TIA, in Japanese hypertensive patients. The study showed a lower rate of primary endpoints in the valsartan arm compared to non-ARB conventional therapies.
A study led by a University of North Carolina researcher found that black patients with high blood pressure experience poorer communication with their doctors compared to white patients. The results showed that black patients had shorter office visits, less biomedical and psychosocial exchange, and less rapport building with their doct...
Researchers found that lowering heart rate with Beta-blockers can increase central aortic pressures in older individuals with high blood pressure, leading to reduced stroke prevention. The study suggests that alternative treatments may be more effective in this population.
New research finds that mortality among patients with idiopathic pulmonary arterial hypertension (IPAH) awaiting lung transplant has not decreased, despite implementation of a new allocation system. The study suggests that key prognostic indicators in IPAH are not adequately captured by the current LAS algorithm.
Research published by the American Academy of Neurology links high blood pressure to cognitive impairment in people over 45. The study found that those with high diastolic blood pressure were more likely to experience memory and thinking problems.
A new study published in Obesity and Weight Management explores the link between obesity and erectile dysfunction, finding that excess weight increases the risk of ED due to atherosclerosis-related hypertension and hormonal changes. Research shows that weight loss and increased physical activity can improve symptoms.
A recent study found carvedilol to be more effective in preventing variceal bleeding in cirrhotic patients compared to traditional treatment with variceal band ligation. The results showed that carvedilol reduced the risk of bleeding by 10% compared to VBL, while survival rates remained unchanged.
Researchers discovered a link between the anti-aging gene klotho and reduced high blood pressure, reversing kidney damage. The study shows that increasing klotho expression can lower blood pressure for at least 12 weeks and potentially prevent hypertension.
Researchers link high blood pressure to multiple sclerosis and suggest a safe, inexpensive drug lisinopril could be an effective treatment option. The study found that lisinopril controls blood pressure by blocking an enzyme that converts angiotensin's precursor into the active hormone.
Sumita B. Mitra's research on dental materials has restored millions of decayed teeth, while William E. Mickols and John Cadotte invented filters to desalinate seawater, providing fresh water for millions worldwide. Their innovations have led to significant breakthroughs in medicine and technology.
A randomized trial found that targeting systolic blood pressure below 130 mmHg reduced left ventricular hypertrophy and clinical events, compared to a target of 140 mmHg. The study suggests that lowering systolic blood pressure in nondiabetic patients with hypertension may be beneficial.
A DASH-style diet high in calcium, potassium, and magnesium, and low in sodium, was found to reduce the risk of kidney stone formation. Participants with higher scores on this dietary approach were between 40-45% less likely to develop kidney stones than those with lower scores.
A study published in The Lancet recommends inducing labor at 37 weeks for pregnant women with mild hypertensive disorders like gestational hypertension or mild pre-eclampsia. This approach reduces the risk of poor maternal outcomes, severe hypertension, HELLP syndrome, and caesarean sections.
A recent study found a strong association between sedentary behaviors like TV viewing and screen time, and elevated blood pressure in children. The researchers discovered that the risk was present even after adjusting for age, sex, height, and percentage of body fat.
A study published in Neurology found that people over 60 with high blood pressure are more likely to experience silent strokes. High blood pressure increases the risk by 60%, while white matter hyperintensities nearly double the likelihood of silent strokes.
Researchers found that centrally-acting ACE inhibitors, which cross the blood-brain barrier, may reduce inflammation and cognitive decline in patients with hypertension. These medications showed a significant association with lower rates of mental decline, particularly those taking drugs like captropril and lisinopril.
A study found that men who exercised regularly, drank moderately, didn't smoke, were not overweight, and followed a healthy diet had a lower lifetime risk of heart failure. The remaining lifetime risk was approximately 2-4% higher in men with hypertension compared to those without.
A study of 83,882 young adult women found that adopting six low-risk lifestyle factors was independently associated with lower risk of developing high blood pressure. The combination of normal BMI, daily vigorous exercise, DASH-style diet, modest alcohol intake, and folic acid supplementation resulted in an 80% lower risk of hypertension.
Research conducted by Yale University researchers found that women with preeclampsia in previous pregnancies are at higher risk of hypertension after pregnancy. Additionally, preterm delivery, preeclampsia, and low-birth weight tend to recur and increase the risk of complications in future pregnancies.
A study found five genetic variants associated with high systolic blood pressure in African-Americans, suggesting potential new treatments. The variants were located near genes that code for proteins involved in hypertension regulation, offering hope for improved prevention and treatment options.
A study found that transforming growth factor B1 (TGF-B1) is higher in blacks compared to whites, increasing the risk of hypertension and renal disease. Higher levels of TGF-B1 are also linked to body mass index and metabolic syndrome.
Researchers found that treatment intensification can improve blood pressure control in patients with varying levels of adherence, challenging a widely held assumption. The study's lead author recommends further studies to determine the most effective management strategy for uncontrolled hypertension and suboptimal adherence.
The Hypertension and Vascular Research Center at Wake Forest University School of Medicine has received a five-year, $6.643 million grant renewal from the National Heart, Lung and Blood Institute to continue studying hypertension and vascular disease.
A new science review highlights multiple health benefits of dairy foods, including improved bone health, lower blood pressure and a reduced risk of obesity. Dairy consumption is recommended for children and adults to meet daily nutrient needs.
Several biomarkers, including CRP and N-BNP, showed minimal added benefit in predicting cardiovascular events compared to conventional risk factors. The use of these biomarkers did not result in significant improvements in reclassification of individuals to new risk categories or changes in therapy.
New research warns of increasing rates of hypertension in Latin America, which poses a mounting threat to economies if not addressed. To combat this, policymakers and healthcare providers must work together to implement core policy changes, including detection, diagnosis, treatment, and control of high blood pressure.
Researchers from Boston University compared three measures of treatment intensity in hypertension care and found that the standard-based method predicts blood pressure control most effectively. The norm-based method was not a valid predictor of blood pressure control due to its non-linear relationship with systolic blood pressure.
Research found that obese children as young as 7 years old have abnormal blood markers predicting cardiovascular disease. Simple obesity can raise risk before the metabolic syndrome develops.
A new study from UC Davis found that retirement-aged Americans in lower-status occupations tend to have higher rates of hypertension. The researchers analyzed data from over 22,000 Americans and found a strong correlation between occupation and hypertension, suggesting that job history may be an important factor in understanding the de...
A study estimates that approximately 1.68 million US men over 50 years old suffer from dry eye disease, which increases with age and is associated with high blood pressure and certain medications. The prevalence of the condition rises significantly among older men, particularly those aged 75 and above.
Researchers found that high blood pressure, excessive weight, smoking, and diabetes significantly increased the size of the heart's left ventricle over short-term (4 years) and long-term (16 years) periods. These risk factors can be directly targeted for prevention and lowering may potentially lower heart failure burden.
Middle-aged adults who sleep fewer hours are more likely to have high blood pressure and experience worsening blood pressure over time. The study, which included 578 adults, found that each hour of reduction in sleep duration was associated with a 37% increase in the odds of developing high blood pressure.
Researchers found that doctors who treat patients with complex conditions provide high-quality care, even better than expected. This suggests that pay-for-performance initiatives may not penalize healthcare providers for caring for the sickest patients.
A simplified chart created by a pediatrician can help identify children with high blood pressure, improving diagnosis rates. The revised chart uses age and gender to determine abnormal readings, reducing the need for height percentile verification.
A study comparing NFL players' health to that of other healthy young men found lower incidence of impaired fasting glucose and similar prevalence of abnormal cholesterol levels. However, NFL players had a significantly higher prevalence of high blood pressure and prehypertension compared to the general population.
A new study suggests that cytomegalovirus (CMV) is a cause of high blood pressure, a leading risk factor for heart disease, stroke and kidney disease. The virus can lead to the development of atherosclerosis, or hardening of the arteries, when coupled with other risk factors.
A new study confirms the benefits of diuretic drugs in reducing the risk of heart failure and stroke in high blood pressure patients. The research, which analyzed data from multiple clinical trials, found that diuretics work as well or better than other medications in preventing major complications of hypertension.
A Swedish study found that women who followed the Dietary Approaches to Stop Hypertension (DASH) diet had a lower risk of heart failure. The study analyzed data from 36,019 women and found that those with higher DASH scores had half the rate of heart failure compared to those with lower scores.
A large study led by Beth Israel Deaconess Medical Center demonstrates that following the DASH diet significantly reduces women's risk of developing heart failure. The diet, high in plant foods and low in sugar and saturated fats, also lowers blood pressure.
Researchers found that increased O-GlcNAc levels damage blood vessels by reducing nitric oxide production, increasing blood pressure and vessel contraction. This discovery could lead to new treatments targeting the O-GlcNAc pathway.
A large-scale genome-wide association study identified eight key genes associated with high blood pressure, including ATP2B1, CACNB2, and CYP17A1. The research provides new insights into blood pressure regulation and may lead to the development of novel therapeutic approaches.
Researchers at Johns Hopkins University School of Medicine identified common genetic changes associated with blood pressure and hypertension, including ATP2B1 and SH2B3. The study may lead to advances in hypertension therapy and the formation of early detection systems.
A global research collaboration has identified eight DNA regions associated with blood pressure and hypertension, six of which have never been linked to the condition before. The study found that genetic variants in these regions may hold promise for new treatments or even prevention.
A one-year study found that a computer-based system significantly lowered high blood pressure in participants, reducing systolic and diastolic pressures by an average of 11.9mmHg and 6.6mmHg, respectively. The system's regular feedback and automated alerts encouraged patients to take their medication as prescribed.
Children with high blood pressure are more likely to have learning disabilities and ADHD, with a four-fold increased risk. The study also found that hypertensive children have difficulties in goal-directed tasks and working memory.
Scientists find novel salt storage site in the skin and a gene regulator controlling blood pressure regulation. A high-salt diet leads to increased lymphatic vessels, but the process behind this storage and its relevance to human disease are not yet fully understood.
A new study found that smoking, high blood pressure, and being overweight are the leading preventable causes of death in the US, responsible for 467,000, 395,000, and 216,000 premature deaths annually. The study's findings highlight the importance of modifiable risk factors and call for increased public health efforts to address these ...
A comprehensive study estimates that smoking and high blood pressure cause nearly half of the US adults' preventable deaths. The analysis highlights the potential for targeted interventions to reduce these deadly risk factors.
A study by Luca Saba found that diabetes and hypertension are significantly related to carotid artery wall thickness, a major risk factor for heart attack and stroke. Patients with CAWT greater than 1mm in diabetes or hypertension are at increased risk of stroke.
A new study reveals that two-thirds of the racial gap in death rates among African Americans and Caucasians is due to preventable or treatable conditions. The major contributor to this disparity is conditions with effective treatments, such as stroke, diabetes, and hypertension.
A peer-reviewed journal highlights RESPeRATE's effectiveness in treating hypertension, emphasizing the importance of individualized attention and non-traditional methods. Nurse practitioners are encouraged to play a leading role in providing comprehensive care to hypertensive patients.
A University of Michigan study found that grapes lowered blood pressure and reduced signs of heart damage by altering cellular activity. The researchers suggest that the phytochemicals in grapes turned on protective genes that reduce damage to the heart muscle.
The American College of Physicians has released a guidebook and DVD to assist patients in managing high blood pressure, a condition that increases the risk of heart disease, stroke, and kidney problems. The resource provides information on causes, risk factors, and lifestyle changes to control hypertension.
Researchers Francois Abboud and Ann M. Schreihofer have unraveled how the brain regulates blood pressure and flow through communication with blood vessels. Their work has led to clinical advances, including a pacemaker-like device to lower blood pressure in hypertensive individuals.
A study of 78,061 women found that those with psoriasis were 63% more likely to develop diabetes and 17% more likely to develop hypertension than women without psoriasis. Systemic inflammation in psoriasis may be a biologically plausible explanation for the association.
Young adults who have been incarcerated are more likely to develop high blood pressure and left ventricular hypertrophy. They also face barriers to accessing regular medical care.
A new catheter-based treatment has been successfully trialled to reduce high blood pressure in patients who resist conventional drug treatments. The technique, which disrupts nerves around the kidneys, showed a large and persistent decrease in blood pressure.
A study found that sorafenib dramatically improved the condition of rats with portal hypertension, reducing new blood vessel growth and improving liver function. The results suggest that sorafenib may be an effective therapeutic agent for treating advanced portal hypertension.
A study found that chronic insomnia with short sleep duration is associated with a high risk of hypertension. Participants with severe short sleep duration had a 500% higher risk compared to those who slept more than six hours. The findings highlight the importance of diagnosis and treatment for people with insomnia.