Research on high blood pressure and its consequences. Covers heart-failure prediction, kidney-disease models, AI detection, and cardiovascular risk.
Scientists from Max Planck Institute discover gene SLC4A5 responsible for sodium dysregulation and hypertension. The study found that a genetic defect in this gene can lead to excessive renal retention of sodium and water, resulting in abnormal blood pressure levels.
Researchers found that more than one-quarter of Canadian adults will be diagnosed with hypertension by 2012/13. Higher rates were observed in women older than 65 and in the Atlantic provinces.
A mid-pregnancy test can predict preeclampsia, a late-pregnancy disorder characterized by high blood pressure and excess protein in the urine. Women with high blood pressure during pregnancy are at increased risk of experiencing high blood pressure, kidney problems, and stroke later in life.
A study co-authored by University of Leicester expert identifies key genetic mechanisms controlling blood pressure, including two microRNAs that regulate renin hormone production. This breakthrough could lead to innovative new treatments for high blood pressure.
A new study published in Neurology found that a person's stroke risk profile can also predict their risk of developing memory and thinking problems later in life. The researchers followed 23,752 people with an average age of 64 and found that those with higher stroke risk profiles were more likely to develop cognitive problems.
A recent study by the National Institutes of Health has discovered a correlation between high blood pressure and stroke risk factors with cognitive impairment. The research, which followed over 30,000 participants, found that age, left ventricular hypertrophy, and high blood pressure were independent predictors of cognitive decline.
Research suggests a link between high blood pressure and reduced ability to recognize emotional faces and texts, potentially causing miscommunication and increased distress in social situations. This 'emotional dampening' can lead to distrust, risk-taking behavior, and worsened mental health conditions.
A study by the American Society of Nephrology found that taking blood pressure-lowering medications at bedtime improves blood pressure control and reduces the risk of heart problems. Patients who took their medications before bed had better outcomes than those who took them in the morning.
A study by Heart and Stroke Foundation researcher Dr. Robert Nolan found that e-counselling led to a twofold decrease in blood pressure levels compared to those who didn't participate, improving lifestyle and quality of life.
A UBC study found that Black Canadians with darker skin are more likely to report poor overall health compared to those with lighter skin. The study suggests that colourism can negatively affect health and highlight the importance of considering racial identity mismatches.
A new study found that middle-aged women with Restless Legs Syndrome are at a higher risk of developing high blood pressure. The study, published in the American Heart Association journal Hypertension, found that women who experienced more frequent symptoms of RLS were more likely to have high blood pressure.
Researchers at Oregon Health & Science University discovered that calcineurin inhibitors spurs the production of a natural protein in the kidney, leading to hypertension. A thiazide diuretic drug blocks this protein, reducing hypertension in mice and showing promise for transplant patients with similar issues.
A study by the University of Manitoba and the Manitoba Metis Federation found a 25% higher stroke rate among Metis compared to other Manitobans. The research identified a link between Metis-specific health issues, such as smoking, diabetes, and high blood pressure, which increase stroke risk.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found a link between shift work and increased cortisol levels. This association was discovered in individuals working shifts at a young age and may contribute to cardiovascular risk.
Research from the University of California - San Diego School of Medicine found that people with prehypertension have a 55% higher risk of experiencing a future stroke than those without. The study analyzed 12 prospective cohort studies involving over 518,000 participants and found that even high-but-normal blood pressure elevates stro...
A randomized controlled clinical study demonstrated that RESPeRATE can significantly relieve symptoms of heart failure in elderly patients. After 4 weeks of twice daily treatment sessions, patients showed a reduction in the severity of CHF measured by NYHA classification and dyspnea.
A large study found that high blood pressure is associated with a higher risk of developing cancer and dying from the disease, particularly in men. The study analyzed data on blood pressure and cancer incidence and death in over 289,000 participants.
Kidney damage allows detrimental enzymes to wreak havoc on fluid balance, causing protein in the urine, high cholesterol, and swelling. New insights reveal that plasminogen plays a role in activating the epithelial sodium channel (ENaC), leading to excessive sodium absorption and water retention.
Researchers have identified 16 new genetic variations that affect blood pressure, providing a significant step towards better diagnostics and treatment. The discovery was made using genetic data from over 200,000 Europeans and reveals new genetic risk groups to help predict the risk of strokes and heart attacks.
Research reveals that a high-salt diet and obesity trigger abnormal activation of the Rac1 protein in kidney cells, leading to increased blood pressure. This finding offers a potential new therapeutic target for treating salt-sensitive hypertension.
Blacks with prehypertension have a 35 percent greater risk of progressing to high blood pressure than whites. Lifestyle changes such as weight loss and physical activity can reduce the risk of developing high blood pressure for those with prehypertension.
Researchers identified 29 DNA sequence variations linked to blood pressure, suggesting a complex genetic regulatory mechanism. The study pooled data from over 200,000 people worldwide and found common genetic variants in individuals of Asian and African ancestry.
Researchers identified 16 new gene regions associated with blood pressure and confirmed 12 previously discovered ones, providing insights into the genetic mechanisms of hypertension. The study's findings could lead to new therapeutic drug development and improved treatment options for individuals with high blood pressure.
A new study has found that retired racing greyhounds' blood pressure increases significantly when taken to a veterinary clinic, but returns to normal at home. The 'white-coat effect' was observed in 22 greyhounds, with systolic pressures averaging 30 points higher in the hospital than at home.
A 14-year study found a significant increase in ischemic stroke hospitalizations among adolescents and young adults, with nearly one-third of patients aged 15-34 years also diagnosed with hypertension. The study highlights the need for public health initiatives to reduce risk factors for stroke among this age group.
A new study by Joe Vinson found that consuming 6-8 purple potatoes twice daily for a month reduced diastolic blood pressure by 4.3% and systolic pressure by 3.5%. The majority of subjects taking anti-hypertensive drugs still showed a significant decrease in blood pressure.
Researchers recommend low-salt diets, exercise, and weight loss as primary treatments for hypertension. Alternative options like Coenzyme Q10, potassium supplements, and devices like RESPeRATE and Zona Plus may also be effective in managing blood pressure.
Researchers found that African-American endothelial cells produce nearly 90% more microparticles during inflammation than Caucasian cells. This increased production is associated with higher levels of hypertension in individuals.
A UK study published in The Lancet concludes that ambulatory blood pressure monitoring is the most cost-effective way to diagnose hypertension. This method, which involves repeated measurements throughout a 24-hour period, is more accurate and correlates better with cardiovascular outcomes than traditional clinic-based methods.
The new guideline recommends using ambulatory blood pressure monitoring to diagnose high blood pressure, which may lead to a significant reduction in the number of people misdiagnosed with hypertension. The approach is expected to be cost-effective and save money by targeting treatment at those who need it.
Researchers found people with diabetes alone had a 35% higher risk and those with hypertension alone had a 17% higher risk. The study also showed hyperlipidemia reduced the risk by 5%. Regular eye exams are recommended for those at increased risk of glaucoma.
A new study finds that gout prevalence has risen significantly in the US adult population, affecting 8.3 million people, while hyperuricemia affects 43.3 million adults. The study suggests that managing modifiable risk factors like obesity and hypertension could help prevent further escalation of gout and hyperuricemia.
Fetal exposure to nicotine causes permanent changes in blood vessel behavior, leading to high blood pressure and cardiovascular disease in adulthood. This study provides novel information on the fetal programming underlying these risks.
Vanderbilt University researchers found that dopamine in the kidneys plays a crucial role in regulating blood pressure and life span. The study suggests that targeting the kidney dopamine system may be effective in treating hypertension and progressive kidney diseases.
Researchers have identified a protein called MYLIP as a potential new target for lowering LDL cholesterol levels, which are associated with atherosclerotic cardiovascular disease. Additionally, platinum-based drugs have been found to promote anticancer immune responses by disrupting the mechanisms used by tumors to inhibit immune cells.
Researchers have discovered that a protein in blood vessel walls plays a key role in maintaining healthy blood pressure. Malfunctioning of this protein, Kv7.4, contributes to high blood pressure and can be targeted by new treatment strategies.
Climbing the social ladder may reduce the risk of developing high blood pressure among those born into disadvantaged backgrounds. Researchers found that upwardly mobile adults had a 20% lower risk of hypertension, while those who fell further down the social ladder were at increased risk.
New research suggests that obstructive sleep apnea can cause changes in blood vessel function, reducing blood supply to the heart. Treatment with continuous positive airway pressure (CPAP) has been shown to improve blood supply and function in study participants.
Researchers at the University of Strathclyde have identified a heretofore unrecognised pathway regulating calcium activity within blood vessel smooth muscle cells. This discovery may lead to the development of new treatments for hypertension by targeting the constriction and dilation of blood vessels.
Researchers recommend using multiple blood pressure readings to accurately assess control in patients with hypertension, suggesting home monitoring could improve quality of care. For suspected appendicitis, multidetector computed tomography (MDCT) is recommended as standard preoperative care due to its high sensitivity and specificity....
A study published in Archives of Pediatrics & Adolescent Medicine found that adolescent girls who followed a DASH-style diet had smaller gains in overall body mass index (BMI) over 10 years compared to those on other diets. Higher consumption of fruits, whole grains, and low-fat dairy products was associated with less weight gain.
Researchers aim to determine how vitamin D affects cardiac structure and function, vascular function, and left ventricular hypertrophy in blacks with hypertension. The study could identify vitamin D as a safe and effective therapy to stop or reverse cardiac ravages caused by high blood pressure.
A new Canadian blood pressure education program has shown promising results in reducing stroke risk by up to 40%. The program, launched in 11 primary care sites across Ontario, achieved sustained average blood pressure reductions of 6.4/3.8 mmHg after three years.
Researchers identify MKK4 enzyme as a potential therapeutic target for treating cardiac arrhythmias caused by cardiac hypertrophy, leading to sudden cardiac death in young athletes. The study reveals how the enzyme prevents arrhythmias by modifying connexin protein, ensuring synchronized heart contractions.
A recent study analyzing over 14,000 young adults found that nearly 19% have high blood pressure. The analysis contradicts previous estimates from the National Health and Nutrition Examination Survey (NHANES), which reported only 4% of adults in this age group having high blood pressure.
A new study by researchers at the University of North Carolina found that nearly 19% of young adults between 24 and 32 years old have elevated blood pressure. The study analyzed data from over 14,000 participants and found significant disparities in hypertension rates among different demographics.
Researchers found improved hypertension control in Canada, with increased awareness and treatment rates among community-dwelling adults. Despite this progress, one-third of Canadians with hypertension still have uncontrolled blood pressure.
A surgical procedure to remove enlarged tonsils and adenoids may reduce blood pressure in children with OSA, preventing heart damage. In a study of 115 children, adenotonsillectomy resulted in lower blood pressure levels during sleep, restored the normal nighttime dip in blood pressure, and even reduced heart size in some cases.
A large cohort study found a significant association between lower urinary sodium excretion and an increased risk of cardiovascular death. In contrast, higher sodium excretion was not associated with increased hypertension or cardiovascular disease complications. The study's findings challenge current recommendations on reducing salt i...
Tafluprost met primary endpoint in phase III study, showing comparable IOP-lowering effect to timolol. The medication achieved significant IOP reduction from baseline and demonstrated non-inferiority to existing treatments.
Kenji Taylor, a first-year medical student at Penn Med, has been named one of 15 Philadelphia Schweitzer Fellows for 2011-2012. He will launch the 'Cut Hypertension Program' to address hypertension in African American males through blood pressure screenings and preventive lifestyle coaching.
A recent study suggests that low vitamin D levels among black people may contribute to racial differences in hypertension. The research found that nearly 61% of blacks had vitamin D levels in the lowest one-fifth of the population sample, compared to 11% of whites.
A new study identifies vitamin D as a potential contributor to the racial disparity in blood pressure between Blacks and Whites. The research found that low vitamin D levels were associated with elevated blood pressure readings, accounting for a quarter of the difference between the two groups.
The American College of Cardiology and the American Heart Association released the first expert consensus document to help clinicians reduce hypertension risks in older adults. The guidelines recommend targeted blood pressure control measures, including medication selection, dose titration, and lifestyle changes.
Researchers found that salt intake raises blood pressure by disrupting temperature regulation in the cardiovascular system, affecting some individuals more than others. This discovery may lead to a comprehensive theory explaining most cases of high blood pressure.
Researchers found that treating vascular risk factors can help slow memory decline and reduce the risk of developing dementia. Those receiving full treatment were 39% less likely to develop Alzheimer's disease compared to those receiving no treatment.
A study reveals growing disparities in stroke death rates between European countries, with some nations experiencing a significant increase in mortality rates. The research suggests that controlling high blood pressure is crucial to addressing this public health issue.
Researchers from Wisconsin and Texas have identified two EET analogs that effectively lower blood pressure and reduce kidney injury in animal models of hypertension. The findings offer a promising avenue for the development of novel treatments for cardiovascular disease.
The Experimental Biology 2011 conference showcased cutting-edge research in biochemical battle of the bulge, DNA replication, and bone health. Researchers presented findings on obesity, cancer, and gene therapy, highlighting the importance of understanding cellular processes in disease prevention.
The Rheos System, a device that regulates blood pressure like a pacemaker regulates heart rhythm, helped lower blood pressure by 33 points. This substantial drop could require up to five additional drugs to control difficult-to-treat hypertension in patients with resistant hypertension.