Articles tagged with Hypertension
Acute ischemic stroke hospitalizations have declined among middle-aged and older individuals, but risen among those under 35, according to a study by the CDC. The rate of decline was greatest for girls aged 0-4, with a 51% decrease in hospitalizations.
A systematic review found that using a generic blood pressure and heart drug, losartan, instead of branded candesartan could save the UK National Health Service (NHS) £200 million in 2011. This is based on 2009 prescribing figures for primary care alone, with potential savings even higher.
A study published in Proceedings of the National Academy of Sciences found that low doses of losartan improved the effectiveness of two nanotherapeutic approaches against several types of cancer. Losartan normalized the abnormal extracellular matrix of tumors, allowing for better delivery and efficacy of therapies.
A new study published in BMJ found that Pay-for-Performance does not offer benefits to patients with hypertension, despite significant administrative costs. The research analyzed data from over 500,000 patients and found no impact on stroke, heart attacks, or mortality rates.
Researchers discovered that deep brain stimulation can lower blood pressure in people with difficult-to-control high blood pressure. The treatment used electrical pulses to send signals to the brain, resulting in a significant decrease in blood pressure and allowing some patients to stop taking all their blood pressure medications.
A new study suggests that a storytelling approach can help African-Americans with hypertension control their blood pressure through diet and medication adherence. The approach, which involves recognizable community members sharing positive messages, was found to be effective in improving blood pressure control among patients.
Bioactive compounds in berries, particularly anthocyanins found in blueberries, have been shown to reduce the risk of high blood pressure. Consuming at least one serving of blueberries per week can lower the risk by 10% and may contribute to hypertension prevention.
A study by UTMB researchers reveals a significant increase in hypertension prevalence among older Mexican-Americans, with higher rates among those with diabetes and obesity. The study highlights the need for targeted interventions to address these factors and improve hypertension management in this growing population.
A new study published in The Lancet shows that starting treatment with two medicines instead of one produces better and faster results, and fewer side effects. This challenges popular medical practice and could change clinical practice worldwide.
Patients with high blood pressure respond better to combination therapy from the start of treatment, with a mean reduction in systolic blood pressure of 6.5 mm Hg. After switching to combination therapy, patients who initially received monotherapy show improvement but not to the same extent as those on combination therapy from the start.
Research suggests that breathing tobacco smoke can raise the blood pressure of children as young as 4 or 5 years old. Parents who smoke are more likely to have children with high blood pressure, even after adjusting for other risk factors.
A significant increase in MMP-1, an enzyme produced in tissues under conditions of inflammation, was found in the blood vessels of women with preeclampsia, explaining edema and proteinuria. This finding also suggests a new mechanism for hypertension, with PAR1 activation potentially causing blood vessel contraction.
A new model, fullPIERS, predicts adverse maternal outcomes in pre-eclampsia with high accuracy and identifies risk categories for clinicians. The model is built on six variables and performs well in predicting outcomes within 48 hours of hospital admission.
A Washington State University study found that whey-based protein supplements can significantly reduce elevated blood pressure, resulting in a more than six-point reduction in average blood pressure. The study's findings have practical implications for personal health and the dairy industry.
A recent study has found that high blood pressure is more common among black women in the southeastern US compared to white men. The researchers analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) study and discovered significant geographic, racial, and gender differences in hypertension risk.
A recent study by Terrance Wade found that 6.5% to 8% of Canadian children have elevated blood pressure, a concern for their physical health and increased risk of heart disease as adults.
A new review suggests that excessive amounts of fructose may play a role in high blood pressure, diabetes, obesity, and chronic kidney disease. The study recommends restricting added sugars containing fructose for patients with CKD to lower the risk of these health conditions.
A study found that individuals with a common gene variant are 1.5 times more likely to have progressive kidney disease than those with other genotypes. The MYH9 variant was present in 55% of African American patients and associated with a 50% higher risk of death, ESRD, or significant drop in kidney function.
Researchers have identified a potential solution for preventing osteoporosis using potassium citrate supplements. Additionally, waist circumference measurements in children may be a better predictor of heart disease risk than body mass index. Early urine tests can also predict pregnancy complications such as pre-eclampsia.
The Symplicity HTN-2 trial shows that deactivating nerves in the kidneys using radiofrequency energy can significantly reduce blood pressure in patients with treatment-resistant hypertension. The study found a large reduction in systolic blood pressure, and the technique was applied without major complications.
Researchers found that cutting back on salt in teenagers' diets by just one-half teaspoon per day could reduce the number of young adults with high blood pressure by 44-63 percent. Lowering dietary salt can also have numerous benefits, including reducing incidents of coronary heart disease and strokes.
A University of Alberta study found that including pharmacists in primary care teams leads to significant drops in blood pressure among patients with Type 2 diabetes. The collaboration enables direct discussion between healthcare professionals, resulting in better medication management and reduced cardiovascular risk.
A study of 7,981 black and white adults found no link between fatal strokes and vitamin D deficiency among blacks. In contrast, whites with deficient vitamin D levels had a doubled risk of dying from a stroke compared to those with higher levels.
Researchers project a significant reduction in high blood pressure, heart disease, and stroke among adults if teenagers consume less salt each day. A study suggests that reducing sodium intake by 3 grams per day can decrease hypertension rates by 44-63% and coronary heart disease cases by 7-12%.
A study by the University of Leicester found that undetected high blood pressure is associated with a higher risk of dying from coronary heart disease. The research reveals that areas with greater deprivation, more smokers, and more people with diabetes have a higher mortality rate from coronary heart disease.
A new study by University of Rochester Medical Center found that children with high blood pressure are four times more likely to have cognitive problems. Among the study's 201 patients, 101 had hypertension and 18% had learning disabilities, compared to 9% among those without hypertension.
A study by UT Southwestern Medical Center found that the adrenal gland hormone aldosterone increases activity in the nervous system that raises blood pressure. The research suggests that treating hypertension requires targeting not just the kidneys but also the sympathetic nervous system.
A new solar-powered device accurately measures systolic blood pressure with high accuracy, ideal for rural areas. The device costs $32 and has significant savings on battery usage, making it a promising tool to slow the rise in cardiovascular disease.
Chronic kidney disease patients who don't adhere to high blood pressure medications are more likely to have sub-optimal blood pressure control. Improving medication adherence can greatly improve outcomes for these patients.
A study from Cedars-Sinai Heart Institute shows that barbers can improve hypertension control in African-American men by conducting monitoring, education and physician-referral programs. The intervention resulted in 20% more patients with controlled blood pressure compared to the comparison group.
A randomized trial involving 17 black-owned barbershops in Dallas County, Texas found that the enhanced barber-based intervention resulted in greater improvement in hypertension control. The control rate for patrons with hypertension increased from 33.8% to 53.7%, an increase of 19.9%.
Researchers at LSU Health Sciences Center New Orleans have discovered that two brain proteins, Gαq and Gαz, act as valves to regulate vasopressin secretion and water retention in salt-sensitive hypertension. This finding may lead to new treatment options for high blood pressure, congestive heart failure, and cirrhosis of the liver.
Researchers from Florida State University found that consuming watermelon daily can improve arterial function and lower aortic blood pressure in prehypertensive individuals. The study suggests that watermelon's natural source of L-citrulline may prevent the progression from prehypertension to hypertension.
Scientists have discovered a mechanism that raises blood pressure in pre-eclampsia, a potentially deadly condition during pregnancy. Researchers found that the protein angiotensinogen is oxidised and changes shape to release the hormone angiotensin, which then raises blood pressure.
Researchers have uncovered a novel mechanism controlling blood pressure, shedding new light on the causes of pre-eclampsia. The study found a fine-tuning mechanism responsive to tissue oxygen changes, providing potential insights into prevention and treatment.
A national study found that keeping blood pressure at 130/80 mm Hg reduced the risk of disease progression by 27 percent for patients with proteinuria. However, intensive lowering of blood pressure in all African-Americans did not slow disease progression.
Research published in Occupational and Environmental Medicine found that workers exposed to loud noise at work are twice as likely to have serious heart problems as those in quiet workplaces. Workers under 50, particularly men and smokers, were at greater risk.
The Journal of the American Society of Hypertension (JASH) has been selected for inclusion in MEDLINE, a premier bibliographic database of the U.S. National Library of Medicine. JASH's scientific merit and contribution to the field have been recognized through this prestigious recognition.
Researchers have identified a protein called P450 that metabolizes arachidonic acid in blood vessel walls to create EETs, which relax blood vessels and lower blood pressure. This discovery may lead to the development of new blood pressure-lowering agents and treatments for high blood pressure.
Patients treated with terlipressin for gastrointestinal bleeding due to portal hypertension experienced a significant reduction in serum sodium concentration. The study suggests that monitoring serum sodium closely and avoiding high-sodium solutions may help prevent adverse events.
A landmark study by the University of Ottawa Heart Institute reveals that 70% of Ontario adults are either overweight or obese. The analysis also shows a strong link between high blood pressure and above normal BMI, with obesity levels increasing with age.
A recent study suggests that aggressively treating hypertension in African Americans with kidney disease can significantly decrease the number of patients who lose kidney function and require dialysis. The study found a 25% reduction in end-stage kidney disease among those with protein in their urine.
A study of 1,000 men found that those with chronic insomnia and a short sleep duration were four times more likely to die over a 14-year period. The results suggest that public health policy should prioritize the diagnosis and treatment of chronic insomnia in men.
A new study has identified three factors linked to cognitive deficits in type 2 diabetes: high blood pressure, balance issues, and poor health reports. These factors contribute to weaker memory and slower cognitive processing in individuals with Type 2 diabetes.
Research found that black and Hispanic kidney donors are more likely to develop hypertension, diabetes, and chronic kidney disease compared to white donors. The study highlights the need for better pre-donation counseling and post-donation follow-up to address these health disparities.
A new study suggests that common hypertension medications can increase blood pressure in some patients. Researchers found that measuring renin levels through a blood test could help doctors choose the most suitable treatment for their patients, reducing the need for additional medication and improving blood pressure control.
A recent study found that long-term dietary consumption of capsaicin in chili peppers can reduce blood pressure in genetically hypertensive rats by activating the TRPV1 channel and increasing nitric oxide production. This could lead to potential benefits for humans with high blood pressure.
Research suggests that both short and long sleep durations are independently associated with an increased risk of cardiovascular disease. Adults who sleep less than seven hours per day or more than nine hours per night have a higher risk of heart problems compared to those who get average sleep duration.
A large-scale study published by BGU researchers found that normal blood pressure at age 17 can predict hypertension in early adulthood, particularly in teenage boys. The study also revealed that estrogen may protect against hypertension in girls, and that monitoring weight and blood pressure is crucial for adolescents and young adults.
Researchers at the University of Pittsburgh School of Medicine have identified a biochemical pathway regulating blood pressure, involving nitric oxide signaling and proteins thrombospondin-1 (TSP1) and CD47. Blocking this pathway could lead to novel blood pressure-regulating drugs.
A new study found that patients with hypertension who monitor their blood pressure at home and adjust their medication can experience greater falls in blood pressure. The TASMINH2 trial showed significant reductions in systolic blood pressure after 6 months, with no increase in side effects.
Patients with hypertension, diabetes, and coronary artery disease who maintained systolic blood pressure at less than 130 mm Hg did not have improved cardiovascular outcomes compared to usual blood pressure control. Tight blood pressure control was actually associated with increased risk of all-cause mortality.
A study by American Society of Nephrology suggests that consuming foods with high fructose levels can increase the risk of hypertension. Researchers analyzed data from over 4,500 US adults and found a significant association between fructose consumption and elevated blood pressure.
Researchers found that consuming dark chocolate can significantly reduce systolic blood pressure by 5mmHg, comparable to 30 minutes of moderate exercise. This effect is most pronounced in individuals with high blood pressure, potentially reducing the risk of cardiovascular events by 20% over five years.
A recent NIH-supported study has discovered a novel pathway that may lead to the development of new treatments for high blood pressure. By increasing certain proteins in mouse blood vessels, researchers were able to relax the vessels and lower blood pressure, reducing damage to the kidneys compared to normal mice.
Researchers found that Smurf1 is elevated in animal models of PAH and can degrade BMP receptors, leading to excessive growth of vascular cells. This suggests Smurf1 may be an attractive therapeutic target to block disease progression.
The INTERSTROKE study found that high blood pressure, smoking, waist-to-hip ratio, diet, physical activity, lipids, diabetes mellitus, alcohol intake, stress, and depression are significantly associated with stroke. Collectively, these risk factors accounted for 90% of the global risk of stroke.
A study of 825 postmenopausal women found that those with low calcium intake were more likely to develop both osteoporosis and hypertension. Researchers suggest that a low calcium diet may be a risk factor for these conditions.
A study by Medical College of Georgia researchers found a chain of events linking excess fat to increased sodium retention and higher blood pressure. The team identified prostasin, a protease that activates the epithelial sodium channel (ENaC), which regulates salt excretion in the kidneys.
A recent study by MSU psychiatrist Dale D'Mello found that nearly half of patients hospitalized with bipolar disorder also suffer from high blood pressure. The study discovered a link between the severity of bipolar disorders and the level of mania experienced by patients with hypertension.