Articles tagged with Hypertension
A study by UT Southwestern Medical Center found that the adrenal gland hormone aldosterone increases activity in the nervous system that raises blood pressure. The research suggests that treating hypertension requires targeting not just the kidneys but also the sympathetic nervous system.
A study by the University of Leicester found that undetected high blood pressure is associated with a higher risk of dying from coronary heart disease. The research reveals that areas with greater deprivation, more smokers, and more people with diabetes have a higher mortality rate from coronary heart disease.
A new study by University of Rochester Medical Center found that children with high blood pressure are four times more likely to have cognitive problems. Among the study's 201 patients, 101 had hypertension and 18% had learning disabilities, compared to 9% among those without hypertension.
A new solar-powered device accurately measures systolic blood pressure with high accuracy, ideal for rural areas. The device costs $32 and has significant savings on battery usage, making it a promising tool to slow the rise in cardiovascular disease.
Chronic kidney disease patients who don't adhere to high blood pressure medications are more likely to have sub-optimal blood pressure control. Improving medication adherence can greatly improve outcomes for these patients.
A randomized trial involving 17 black-owned barbershops in Dallas County, Texas found that the enhanced barber-based intervention resulted in greater improvement in hypertension control. The control rate for patrons with hypertension increased from 33.8% to 53.7%, an increase of 19.9%.
A study from Cedars-Sinai Heart Institute shows that barbers can improve hypertension control in African-American men by conducting monitoring, education and physician-referral programs. The intervention resulted in 20% more patients with controlled blood pressure compared to the comparison group.
Researchers at LSU Health Sciences Center New Orleans have discovered that two brain proteins, Gαq and Gαz, act as valves to regulate vasopressin secretion and water retention in salt-sensitive hypertension. This finding may lead to new treatment options for high blood pressure, congestive heart failure, and cirrhosis of the liver.
Researchers from Florida State University found that consuming watermelon daily can improve arterial function and lower aortic blood pressure in prehypertensive individuals. The study suggests that watermelon's natural source of L-citrulline may prevent the progression from prehypertension to hypertension.
Scientists have discovered a mechanism that raises blood pressure in pre-eclampsia, a potentially deadly condition during pregnancy. Researchers found that the protein angiotensinogen is oxidised and changes shape to release the hormone angiotensin, which then raises blood pressure.
Researchers have uncovered a novel mechanism controlling blood pressure, shedding new light on the causes of pre-eclampsia. The study found a fine-tuning mechanism responsive to tissue oxygen changes, providing potential insights into prevention and treatment.
A national study found that keeping blood pressure at 130/80 mm Hg reduced the risk of disease progression by 27 percent for patients with proteinuria. However, intensive lowering of blood pressure in all African-Americans did not slow disease progression.
Research published in Occupational and Environmental Medicine found that workers exposed to loud noise at work are twice as likely to have serious heart problems as those in quiet workplaces. Workers under 50, particularly men and smokers, were at greater risk.
The Journal of the American Society of Hypertension (JASH) has been selected for inclusion in MEDLINE, a premier bibliographic database of the U.S. National Library of Medicine. JASH's scientific merit and contribution to the field have been recognized through this prestigious recognition.
Researchers have identified a protein called P450 that metabolizes arachidonic acid in blood vessel walls to create EETs, which relax blood vessels and lower blood pressure. This discovery may lead to the development of new blood pressure-lowering agents and treatments for high blood pressure.
Patients treated with terlipressin for gastrointestinal bleeding due to portal hypertension experienced a significant reduction in serum sodium concentration. The study suggests that monitoring serum sodium closely and avoiding high-sodium solutions may help prevent adverse events.
A landmark study by the University of Ottawa Heart Institute reveals that 70% of Ontario adults are either overweight or obese. The analysis also shows a strong link between high blood pressure and above normal BMI, with obesity levels increasing with age.
A new study has identified three factors linked to cognitive deficits in type 2 diabetes: high blood pressure, balance issues, and poor health reports. These factors contribute to weaker memory and slower cognitive processing in individuals with Type 2 diabetes.
A recent study suggests that aggressively treating hypertension in African Americans with kidney disease can significantly decrease the number of patients who lose kidney function and require dialysis. The study found a 25% reduction in end-stage kidney disease among those with protein in their urine.
A study of 1,000 men found that those with chronic insomnia and a short sleep duration were four times more likely to die over a 14-year period. The results suggest that public health policy should prioritize the diagnosis and treatment of chronic insomnia in men.
A new study suggests that common hypertension medications can increase blood pressure in some patients. Researchers found that measuring renin levels through a blood test could help doctors choose the most suitable treatment for their patients, reducing the need for additional medication and improving blood pressure control.
Research found that black and Hispanic kidney donors are more likely to develop hypertension, diabetes, and chronic kidney disease compared to white donors. The study highlights the need for better pre-donation counseling and post-donation follow-up to address these health disparities.
A recent study found that long-term dietary consumption of capsaicin in chili peppers can reduce blood pressure in genetically hypertensive rats by activating the TRPV1 channel and increasing nitric oxide production. This could lead to potential benefits for humans with high blood pressure.
Research suggests that both short and long sleep durations are independently associated with an increased risk of cardiovascular disease. Adults who sleep less than seven hours per day or more than nine hours per night have a higher risk of heart problems compared to those who get average sleep duration.
A large-scale study published by BGU researchers found that normal blood pressure at age 17 can predict hypertension in early adulthood, particularly in teenage boys. The study also revealed that estrogen may protect against hypertension in girls, and that monitoring weight and blood pressure is crucial for adolescents and young adults.
A new study found that patients with hypertension who monitor their blood pressure at home and adjust their medication can experience greater falls in blood pressure. The TASMINH2 trial showed significant reductions in systolic blood pressure after 6 months, with no increase in side effects.
Researchers at the University of Pittsburgh School of Medicine have identified a biochemical pathway regulating blood pressure, involving nitric oxide signaling and proteins thrombospondin-1 (TSP1) and CD47. Blocking this pathway could lead to novel blood pressure-regulating drugs.
Patients with hypertension, diabetes, and coronary artery disease who maintained systolic blood pressure at less than 130 mm Hg did not have improved cardiovascular outcomes compared to usual blood pressure control. Tight blood pressure control was actually associated with increased risk of all-cause mortality.
A study by American Society of Nephrology suggests that consuming foods with high fructose levels can increase the risk of hypertension. Researchers analyzed data from over 4,500 US adults and found a significant association between fructose consumption and elevated blood pressure.
Researchers found that consuming dark chocolate can significantly reduce systolic blood pressure by 5mmHg, comparable to 30 minutes of moderate exercise. This effect is most pronounced in individuals with high blood pressure, potentially reducing the risk of cardiovascular events by 20% over five years.
A recent NIH-supported study has discovered a novel pathway that may lead to the development of new treatments for high blood pressure. By increasing certain proteins in mouse blood vessels, researchers were able to relax the vessels and lower blood pressure, reducing damage to the kidneys compared to normal mice.
Researchers found that Smurf1 is elevated in animal models of PAH and can degrade BMP receptors, leading to excessive growth of vascular cells. This suggests Smurf1 may be an attractive therapeutic target to block disease progression.
The INTERSTROKE study found that high blood pressure, smoking, waist-to-hip ratio, diet, physical activity, lipids, diabetes mellitus, alcohol intake, stress, and depression are significantly associated with stroke. Collectively, these risk factors accounted for 90% of the global risk of stroke.
A study of 825 postmenopausal women found that those with low calcium intake were more likely to develop both osteoporosis and hypertension. Researchers suggest that a low calcium diet may be a risk factor for these conditions.
A study by Medical College of Georgia researchers found a chain of events linking excess fat to increased sodium retention and higher blood pressure. The team identified prostasin, a protease that activates the epithelial sodium channel (ENaC), which regulates salt excretion in the kidneys.
A recent study by MSU psychiatrist Dale D'Mello found that nearly half of patients hospitalized with bipolar disorder also suffer from high blood pressure. The study discovered a link between the severity of bipolar disorders and the level of mania experienced by patients with hypertension.
Hypertension control increased from 27.3% in 1988-1994 to 50.1% in 2007-2008, with blood pressure decreases among patients with hypertension. However, hypertension prevalence has not decreased in recent years and remains high at approximately 65 million individuals in the US.
A study published in Circulation found an association between sugary drink consumption and elevated blood pressure. Reducing sugar-sweetened beverage intake by just one serving per day was linked to a drop of 1.8 mm Hg in systolic pressure and 1.1 mm Hg in diastolic blood pressure over 18 months.
A study found that academic detailing increased prescribing of thiazide-type diuretics in counties with higher activity levels. The intervention led to a small increase in medication dispensing, but other factors may have blunted its impact.
A large study found that frequent doctor visits can help diabetes patients lower their high blood pressure to normal levels more quickly. Patients who visited their primary care physicians at intervals of one month or less saw a faster decline in blood pressure, with an average time to reach normal levels of just 0.7 months.
A pharmacist-led home blood pressure monitoring program supported by the American Heart Association's Heart 360 website improved blood pressure control for patients with uncontrolled hypertension. The program, which used online tools and clinical pharmacy specialists to adjust medications based on proven protocols, resulted in a signif...
Researchers developed an experimental rat model that mimics the plexiform lesion in pulmonary arterial hypertension (PAH), a life-threatening problem. The model is expected to reveal detailed cellular and molecular mechanisms of severe PAH.
A study by Dr. Ferran Barbé Illa found that CPAP usage can reduce the incidence of cardiovascular events and hypertension in non-sleepy patients with obstructive sleep apnea (OSA). The risk of cardiovascular event decline was observed in patients who used CPAP for at least four hours a night.
A clinical panel recommends that patients' blood pressure should be closely monitored and controlled before starting angiogenesis inhibitors for cancer treatment. Treating a patient's hypertension before treatment begins and maintaining blood pressure below 140/90 mmHg can help control this side effect.
Researchers found that anti-inflammatory drugs can preserve kidney function in hypertensive rats by regulating blood pressure on tiny filters called glomeruli. The study aims to understand how kidneys autoregulate pressure and explore the role of inflammatory factors in arteriole dysregulation.
A study found that individuals with fluctuating blood pressure, in addition to high blood pressure, are at a higher risk of cerebrovascular disease. Fluctuations in blood pressure were associated with an increased risk of cerebrovascular disease, even among those with normal blood pressure.
A study of 2,500 patient records found that medical staff fails to check a child's blood pressure nearly half the time and often misses elevated readings. The consequences are missed development of hypertension and its serious consequences.
Patients with hypertension who excrete slightly increased amounts of protein in the urine, known as microalbuminuria, have an elevated risk of developing heart and kidney problems. Microalbuminuria is associated with a higher risk of chronic kidney disease and cardiovascular complications in non-diabetic patients with hypertension.
Scientists sequenced the genome of the spontaneously hypertensive rat to understand causes of human hypertension. The study identified 788 genes mutated in SHR, including those related to ion transport and immunological processes, which may be causally associated with the disease.
Researchers found that African American boys have higher levels of angiotensin II, a hormone that contributes to high blood pressure, while African American girls have lower levels of protective angiotensin (1-7). These findings suggest that changes in hormone metabolism may occur before blood pressure changes, potentially leading to p...
Researchers investigated the role of Heat Shock Protein-90 (HSP-90) in neural vasoregulation and portal hypertension. They found that HSP-90 is essential for nNOS-mediated vasodilation, a significant finding with potential implications for clinical trials targeting portal hypertension.
Researchers found that dark chocolate reduced damage to blood vessels in cirrhotic patients and lowered blood pressure. In contrast, white chocolate had no beneficial effects on portal hypertension.
A recent NIH study found that vitamin C and E supplements starting in early pregnancy do not reduce the risk of hypertensive disorders and their complications. The supplements did not show any significant difference in preeclampsia or other pregnancy-related hypertension complications, contradicting earlier small studies.
Researchers found an inverse association between high systolic blood pressure and mortality risk, with those having high BP having a favorable prognosis. Patients with higher systolic BP had lower mortality rates compared to those with lower BP levels.
A new study found a direct link between chronic loneliness and increased blood pressure over four years, independent of age and other factors. Even modest levels of loneliness can lead to significant increases in blood pressure.
LCZ696, a new dual-action drug, has been shown to provide significantly greater reductions in blood pressure than the established ARB valsartan. The drug's dual mechanism of action, blocking both angiotensin II and neprilysin, may offer superior benefits for treating hypertension and heart failure.
Researchers at Georgetown University Medical Center found that female sex chromosomes, not just hormones, help regulate blood pressure. Male mice with female sex chromosomes experience hypertension seen in postmenopausal women.
Researchers found that lowering systolic blood pressure below 115 can increase cardiovascular risk for patients with diabetes and coronary artery disease. This new data challenges traditional guidelines recommending lower blood pressure levels as better.
A research team at Oregon Health & Science University has discovered that nitric oxide is a powerful regulator of brain-derived neurotrophic factor (BDNF), a molecule involved in the development and function of the nervous system. This finding could play a significant role in preventing and treating high blood pressure.
A study suggests that variability in blood pressure can be a strong predictor of stroke and other cardiovascular events, independent of mean blood pressure. The researchers found that patients with the most variation in systolic blood pressure were six times more likely to have a stroke.