Research on high blood pressure and its consequences. Covers heart-failure prediction, kidney-disease models, AI detection, and cardiovascular risk.
A new study suggests that higher blood pressure is associated with lower mortality in extremely frail, elderly adults. However, the same association was not found for healthier, robust older adults. The researchers used walking speed as a measure of frailty and found striking results.
Research published in PLOS ONE reveals a significant association between menopausal hormone therapy and high blood pressure in postmenopausal women. Longer use of hormone therapy was found to increase the odds of developing high blood pressure, although this risk decreased with age.
A new UC Davis study found that being overweight or obese alone is not linked to an increased risk of death in the short-term. However, severely obese individuals with diabetes or hypertension do face a higher risk of mortality, emphasizing the importance of weight loss and managing co-occurring health conditions.
A patient registry has yielded crucial data on the clinical features and outcomes of fibromuscular dysplasia (FMD), a non-inflammatory vascular disease. The study found that 91% of patients are women diagnosed in their prime of life, with an average delay in diagnosis of four years from symptom onset.
A recent study found that gout and hyperuricemia affect 8.3 million and 43.3 million Americans, respectively, with high rates of related medical disorders like hypertension, chronic kidney disease, and obesity.
A new study found that modified bariatric surgery can resolve or improve Type 2 diabetes in obese and diabetic patients, regardless of body mass index (BMI). The procedure showed high success rates in reducing blood sugar levels and eliminating insulin needs.
A study found that a high-salt diet can damage blood vessels, increasing the risk of developing hypertension. Researchers analyzed data from over 5,500 men and women and found that those consuming the most sodium were 21-86% more likely to develop high blood pressure.
Researchers at the University of Michigan Health System discovered that digoxin, a centuries-old heart drug, enhances the body's natural protection against high blood pressure and heart failure. By activating RGS proteins, digoxin may improve survival rates in patients with congestive heart failure.
A Wayne State University School of Medicine study found that 90.7% of patients with hypertension also had hidden heart disease, emphasizing the need for early detection and treatment. The study's results have significant implications for preventing cardiovascular disease in high-risk populations.
A recent study found that meditation can lower left ventricular mass in black teens with high blood pressure, reducing the risk of future cardiovascular disease. School records also showed significant behavioral improvements in the meditation group.
Researchers found that standard measures of clinical care for blood pressure are misleading and incomplete, while a new experimental measure provides a clearer picture of patients' needs. The study suggests prioritizing patients most likely to benefit from treatment.
A new study from Henry Ford Hospital found that individuals with insomnia are more likely to develop hypertension due to frequent nighttime wakings and delayed sleep latency. The research highlights the importance of addressing sleep disorders to prevent related health issues.
Researchers discovered a brain pathway regulating renal excretion of sodium and blood pressure control. Gαi2 protein levels change with dietary sodium intake, influencing blood pressure and kidney function.
Two studies examined the effectiveness of CPAP treatment in reducing cardiovascular outcomes in adults with obstructive sleep apnea (OSA). Despite finding no significant reduction in hypertension or cardiovascular events, the studies suggest that OSA may be an independent risk factor for developing new-onset hypertension.
Researchers found that hunter-gatherers like the Tsimane people in Bolivia have lower age-related increases in blood pressure and less risks of atherosclerosis. The Tsimane diet is high in fruits, vegetables, and potassium, and low in calories, salt, and alcohol. This study challenges traditional views on modernization's impact on health.
A minimally invasive procedure called renal denervation disrupts overactive sympathetic nerves, lowering blood pressure in CKD patients with hypertension. The study found no worsening of kidney function, indicating the procedure is safe for those with CKD.
A large cohort study found that history of palpitations and hypertension are significant risk factors for atrial fibrillation in both men and women. Palpitations increased the risk of AF by 62% in women and 91% in men, while hypertension doubled the risk in women and increased it by 40% in men.
A study found that narrower central retinal arteriolar equivalent (CRAE) is associated with a higher six-year incidence of any cardiovascular disease and lower extremity arterial disease. Larger retinal venular diameter, on the other hand, was linked to an increased risk of hypertension.
Research found that moderate fitness levels can lower hypertension risk by 34% for those with a parent's high blood pressure, while highly fit individuals have a 70% lower risk. The study of over 6,000 participants suggests that even realistic exercise can provide significant health benefits.
Research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2012 found that home telemonitoring with pharmacist-led support improved blood pressure control in patients with uncontrolled high blood pressure. The study, which involved 450 patients, showed a significant reduction in blo...
Researchers have discovered a new class of malaria transmission-blocking compounds that work by inhibiting bumped kinase I, blocking the parasite's infectious stage. Genetic variation is also linked to high blood pressure, with researchers finding that inhibiting renin pathway activity can return blood pressure to normal levels.
A pioneering study found that increased maternal choline intake during pregnancy can decrease children's chances of developing hypertension and diabetes. The researchers believe choline alters gene expression patterns involved in cortisol production, potentially reducing stress-related diseases.
A new study challenges traditional risk factors for contrast-induced nephrotoxicity, finding that patients with history of renal disease, hypertension, and heart disease are at greater risk. In contrast, diabetes is not a significant predictor of reduced renal function.
Researchers found that teenagers with abnormally high uric acid levels were twice as likely to have high blood pressure. Elevated uric acid persisted even after adjusting for other factors, suggesting it may be an independent driver of high blood pressure.
A new study at the University of Rochester Medical Center found that fetal growth restriction, a potential cause of stillbirth, is less common in obese pregnancies. In contrast, slow-growing babies are more prevalent among normal-weight women. The researchers suggest that missed diagnoses may not be a major concern in obese pregnancies.
A newly launched clinical trial at URMC is testing whether lower doses of an established blood pressure medication can provide the same benefits as a standard dose, potentially reducing side effects and costs. The study aims to learn how varying amounts of the medication affect patients with mild hypertension.
Researchers found that moxonidine, a second-generation anti-hypertensive drug, can improve heart function and survival without affecting blood pressure in an animal model. The study also showed the drug's beneficial effects on oxidative stress and insulin resistance.
A new Harvard report presents preliminary data showing that taxing salt products or implementing industry reductions can lead to significant reductions in cardiovascular disease deaths. The study found that these strategies could save money by reducing healthcare costs associated with hypertension and CVD events.
A 25% increase in high blood pressure screening in 19 developing countries could reduce CVD events and deaths by up to 3%. The study found that only one-third of people with high blood pressure are aware of their condition, and even fewer receive treatment.
The Society for Experimental Biology and Medicine (SEBM) has awarded ten young investigators for their groundbreaking research in the field of biomedical sciences. The awardees include Jie Xie and Zachary Berwick from Indiana University, who investigated human adipose-derived stem cells and coronary microvascular dysfunction respectively.
A new study presented at the World Congress of Cardiology found that high normal blood pressure becomes less of a risk factor for incident cardiovascular disease and coronary heart disease with age. The study showed similar risks for diagnosed high blood pressure across all age groups.
A Swedish study found that consuming low-fat dairy products reduces the risk of stroke in adults. Low-fat dairy foods are rich in vitamins and minerals such as calcium, potassium, and vitamin D, which may help lower blood pressure and reduce the risk of ischemic stroke.
A review of 29 clinical trials found that taking an average of 500 milligrams of vitamin C daily reduced blood pressure by 3.84 millimeters of mercury in the short term. However, more research is needed to understand its implications as a treatment for high blood pressure.
A recent study published at the World Congress of Cardiology found that regular exercise significantly reduces the risk of death from cardiovascular disease in individuals with high blood pressure. The study involved over 434,000 participants and revealed a significant difference in mortality risks between physically active and inactiv...
A recent study published in the European Heart Journal found that RAAS inhibitors significantly reduced all-cause and cardiovascular mortality in patients with high blood pressure. The treatment was shown to have a beneficial effect on mortality, particularly for ACE inhibitor users.
Researchers found that epigenetic mechanisms, such as reduced DNA methylation, contribute to high blood pressure and increased susceptibility to forming blood clots in pregnant women with preeclampsia. Inhibition of thromboxane synthase or dietary supplementation with folate may provide potential treatments for this condition.
Researchers found that small arteries showed signs of artery damage and reduced compliance after just six weeks on a high-fat diet, while large arteries remained unaffected. This early stage of damage may be the first step in developing high blood pressure.
Researchers found that over 68% of participants failed to take medication daily, with young men who smoke and drink alcohol being the least likely to follow treatment. High rates of hypertension remain steady in the region, contrary to Western Europe's decline.
A study found that moderate isoflavone intake can lower systolic blood pressure in young adults, with a notable benefit for African Americans. Isoflavones may help compensate for endothelial dysfunction, a condition that plays a bigger role in hypertension in African Americans.
Internet-based telemedicine systems lead to more timely treatment decisions and medication adjustments for patients with high blood pressure. Patients who reported frequent blood pressure readings via a web-based portal received more appropriate pharmacotherapy and an overall reduction in cardiovascular risk.
Research found that selective serotonin re-uptake inhibitor antidepressants may increase the risk of pregnancy-induced hypertension by 60%, with one SSRI associated with an 81% increase. Women should consult their doctor if concerned, as discontinuation can lead to depressive relapses and post-partum depression.
Researchers at Cleveland Clinic discovered that corin enzyme deficiency in the uterus may be an underlying cause of pre-eclampsia. The study found that many patients with pre-eclampsia had low levels of corin and identified corin gene mutations.
A study published by the American Heart Association found that orthostatic hypotension may be associated with a higher risk of developing heart failure, particularly in individuals aged 45-55. High blood pressure was also found to contribute to this association.
A study led by UCSF researchers found that women with mild retinopathy are more likely to experience cognitive decline and related brain changes. The findings suggest retinopathy could serve as a simple eye screening tool for detecting early stages of vascular disease.
Prolonged space travel has been found to cause brain and eye abnormalities in astronauts, similar to those seen in intracranial hypertension of unknown cause. MRI scans revealed optic nerve expansion, eyeball flattening, and pituitary gland changes in astronauts exposed to microgravity for extended periods.
Research suggests that T cells play a role in stress-dependent hypertension, and that medications targeting the immune system may also help control anxiety disorders. Mice studies found that T cell deficiency led to reduced blood pressure sensitivity to stress.
A study found that consuming 2-3 small purple potatoes per day reduces blood pressure by 4% without causing weight gain. This effect is attributed to the high levels of antioxidant compounds in these potatoes, which may have similar effects to ACE-inhibitor medications.
Researchers found that systolic blood pressure above 140/90 is associated with increased risk of end-stage renal disease in patients with chronic kidney disease. The study's findings challenge current guidelines, which recommend a systolic pressure of 130/80 or lower.
A study in PLOS Medicine found that tobacco smoking and high blood pressure account for the majority of deaths among Japanese adults. Reducing exposure to these risk factors could extend life expectancy by 1.4 years, according to researchers.
A randomized controlled trial found that patient education plus positive-affirmation induction and self-affirmation improved medication adherence in hypertensive African-Americans compared to patient education alone. The PA group had a 42% medication adherence rate at 12 months, whereas the PE group had a 36% rate.
A new study by NYU School of Medicine reveals that positive affirmation, combined with patient education, improves medication adherence rates among hypertensive African-Americans. The study found a 22% increase in adherence rates among participants who received the intervention.
A rare kidney disease study reveals how sodium and potassium levels are moderated in the body, shedding light on hypertension and familial high blood pressure disease. Researchers identified novel mutations linked to increased sodium activity and decreased potassium activity, providing a better understanding of this inherited condition.
Researchers discovered a common mechanism regulating blood pressure in humans through a sweeping genetic analysis of a rare disease. The study identified two genes interacting to control salt and potassium balance in the kidney.
Researchers at Boston University School of Medicine debunked the concept that excess salt causes high blood pressure by stimulating the sympathetic nervous system to produce adrenalin, causing artery constriction. The study suggests that diuretics may not be enough to treat hypertension cases associated with renal failure and recommend...
Researchers found that delaying effective hypertension treatment for up to a year results in small-quality adjusted life expectancy loss, but longer delays cause significant damage. The study suggests patients and providers focus on diabetes self-management and lifestyle modification within the first year after diagnosis.
A new study led by Patricia Coogan found that cumulative levels of nitrogen oxides increase the risks of type 2 diabetes and hypertension in African-American women. Exposure to particulate matter also showed a significant association with increased risk, but evidence was weaker.
A new study from Northwestern University finds that a significant increase in blood pressure during middle age increases the risk of heart attack or stroke. Maintaining low blood pressure early on can reduce this risk, with those who keep their blood pressure low having a significantly lower risk.
Researchers have discovered a molecular pathway that can help reduce cardiac damage caused by an enlarged heart, a common result of hypertension or a heart attack. The pathway, activated by stretch of adult cardiac cells, promotes the release of VEGF, which protects cardiac function and keeps cells alive.
Inaccurate blood pressure measurements from faulty techniques result in misclassified patients and potentially different treatment decisions. A study published by the University of New Mexico found that 93% of patients have different blood pressure readings when using outdated versus updated guidelines.
A recent study has found that nearly a third of children with sickle cell disease have suffered silent strokes, highlighting the need to identify early signs of anemia and high blood pressure. Researchers believe anemia is the key factor contributing to these risk silent strokes.