Articles tagged with Hypertension
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Researchers have identified 16 new genetic variations that affect blood pressure, providing a significant step towards better diagnostics and treatment. The discovery was made using genetic data from over 200,000 Europeans and reveals new genetic risk groups to help predict the risk of strokes and heart attacks.
Blacks with prehypertension have a 35 percent greater risk of progressing to high blood pressure than whites. Lifestyle changes such as weight loss and physical activity can reduce the risk of developing high blood pressure for those with prehypertension.
Researchers identified 16 new gene regions associated with blood pressure and confirmed 12 previously discovered ones, providing insights into the genetic mechanisms of hypertension. The study's findings could lead to new therapeutic drug development and improved treatment options for individuals with high blood pressure.
Researchers identified 29 DNA sequence variations linked to blood pressure, suggesting a complex genetic regulatory mechanism. The study pooled data from over 200,000 people worldwide and found common genetic variants in individuals of Asian and African ancestry.
A new study has found that retired racing greyhounds' blood pressure increases significantly when taken to a veterinary clinic, but returns to normal at home. The 'white-coat effect' was observed in 22 greyhounds, with systolic pressures averaging 30 points higher in the hospital than at home.
A 14-year study found a significant increase in ischemic stroke hospitalizations among adolescents and young adults, with nearly one-third of patients aged 15-34 years also diagnosed with hypertension. The study highlights the need for public health initiatives to reduce risk factors for stroke among this age group.
A new study by Joe Vinson found that consuming 6-8 purple potatoes twice daily for a month reduced diastolic blood pressure by 4.3% and systolic pressure by 3.5%. The majority of subjects taking anti-hypertensive drugs still showed a significant decrease in blood pressure.
Researchers recommend low-salt diets, exercise, and weight loss as primary treatments for hypertension. Alternative options like Coenzyme Q10, potassium supplements, and devices like RESPeRATE and Zona Plus may also be effective in managing blood pressure.
Researchers found that African-American endothelial cells produce nearly 90% more microparticles during inflammation than Caucasian cells. This increased production is associated with higher levels of hypertension in individuals.
The new guideline recommends using ambulatory blood pressure monitoring to diagnose high blood pressure, which may lead to a significant reduction in the number of people misdiagnosed with hypertension. The approach is expected to be cost-effective and save money by targeting treatment at those who need it.
A UK study published in The Lancet concludes that ambulatory blood pressure monitoring is the most cost-effective way to diagnose hypertension. This method, which involves repeated measurements throughout a 24-hour period, is more accurate and correlates better with cardiovascular outcomes than traditional clinic-based methods.
Researchers found people with diabetes alone had a 35% higher risk and those with hypertension alone had a 17% higher risk. The study also showed hyperlipidemia reduced the risk by 5%. Regular eye exams are recommended for those at increased risk of glaucoma.
A new study finds that gout prevalence has risen significantly in the US adult population, affecting 8.3 million people, while hyperuricemia affects 43.3 million adults. The study suggests that managing modifiable risk factors like obesity and hypertension could help prevent further escalation of gout and hyperuricemia.
Fetal exposure to nicotine causes permanent changes in blood vessel behavior, leading to high blood pressure and cardiovascular disease in adulthood. This study provides novel information on the fetal programming underlying these risks.
Vanderbilt University researchers found that dopamine in the kidneys plays a crucial role in regulating blood pressure and life span. The study suggests that targeting the kidney dopamine system may be effective in treating hypertension and progressive kidney diseases.
Researchers have identified a protein called MYLIP as a potential new target for lowering LDL cholesterol levels, which are associated with atherosclerotic cardiovascular disease. Additionally, platinum-based drugs have been found to promote anticancer immune responses by disrupting the mechanisms used by tumors to inhibit immune cells.
Researchers have discovered that a protein in blood vessel walls plays a key role in maintaining healthy blood pressure. Malfunctioning of this protein, Kv7.4, contributes to high blood pressure and can be targeted by new treatment strategies.
Climbing the social ladder may reduce the risk of developing high blood pressure among those born into disadvantaged backgrounds. Researchers found that upwardly mobile adults had a 20% lower risk of hypertension, while those who fell further down the social ladder were at increased risk.
New research suggests that obstructive sleep apnea can cause changes in blood vessel function, reducing blood supply to the heart. Treatment with continuous positive airway pressure (CPAP) has been shown to improve blood supply and function in study participants.
Researchers at the University of Strathclyde have identified a heretofore unrecognised pathway regulating calcium activity within blood vessel smooth muscle cells. This discovery may lead to the development of new treatments for hypertension by targeting the constriction and dilation of blood vessels.
Researchers recommend using multiple blood pressure readings to accurately assess control in patients with hypertension, suggesting home monitoring could improve quality of care. For suspected appendicitis, multidetector computed tomography (MDCT) is recommended as standard preoperative care due to its high sensitivity and specificity....
A study published in Archives of Pediatrics & Adolescent Medicine found that adolescent girls who followed a DASH-style diet had smaller gains in overall body mass index (BMI) over 10 years compared to those on other diets. Higher consumption of fruits, whole grains, and low-fat dairy products was associated with less weight gain.
Researchers aim to determine how vitamin D affects cardiac structure and function, vascular function, and left ventricular hypertrophy in blacks with hypertension. The study could identify vitamin D as a safe and effective therapy to stop or reverse cardiac ravages caused by high blood pressure.
A new Canadian blood pressure education program has shown promising results in reducing stroke risk by up to 40%. The program, launched in 11 primary care sites across Ontario, achieved sustained average blood pressure reductions of 6.4/3.8 mmHg after three years.
Researchers identify MKK4 enzyme as a potential therapeutic target for treating cardiac arrhythmias caused by cardiac hypertrophy, leading to sudden cardiac death in young athletes. The study reveals how the enzyme prevents arrhythmias by modifying connexin protein, ensuring synchronized heart contractions.
A recent study analyzing over 14,000 young adults found that nearly 19% have high blood pressure. The analysis contradicts previous estimates from the National Health and Nutrition Examination Survey (NHANES), which reported only 4% of adults in this age group having high blood pressure.
A new study by researchers at the University of North Carolina found that nearly 19% of young adults between 24 and 32 years old have elevated blood pressure. The study analyzed data from over 14,000 participants and found significant disparities in hypertension rates among different demographics.
A surgical procedure to remove enlarged tonsils and adenoids may reduce blood pressure in children with OSA, preventing heart damage. In a study of 115 children, adenotonsillectomy resulted in lower blood pressure levels during sleep, restored the normal nighttime dip in blood pressure, and even reduced heart size in some cases.
Researchers found improved hypertension control in Canada, with increased awareness and treatment rates among community-dwelling adults. Despite this progress, one-third of Canadians with hypertension still have uncontrolled blood pressure.
A large cohort study found a significant association between lower urinary sodium excretion and an increased risk of cardiovascular death. In contrast, higher sodium excretion was not associated with increased hypertension or cardiovascular disease complications. The study's findings challenge current recommendations on reducing salt i...
Kenji Taylor, a first-year medical student at Penn Med, has been named one of 15 Philadelphia Schweitzer Fellows for 2011-2012. He will launch the 'Cut Hypertension Program' to address hypertension in African American males through blood pressure screenings and preventive lifestyle coaching.
Tafluprost met primary endpoint in phase III study, showing comparable IOP-lowering effect to timolol. The medication achieved significant IOP reduction from baseline and demonstrated non-inferiority to existing treatments.
A new study identifies vitamin D as a potential contributor to the racial disparity in blood pressure between Blacks and Whites. The research found that low vitamin D levels were associated with elevated blood pressure readings, accounting for a quarter of the difference between the two groups.
A recent study suggests that low vitamin D levels among black people may contribute to racial differences in hypertension. The research found that nearly 61% of blacks had vitamin D levels in the lowest one-fifth of the population sample, compared to 11% of whites.
The American College of Cardiology and the American Heart Association released the first expert consensus document to help clinicians reduce hypertension risks in older adults. The guidelines recommend targeted blood pressure control measures, including medication selection, dose titration, and lifestyle changes.
Researchers found that salt intake raises blood pressure by disrupting temperature regulation in the cardiovascular system, affecting some individuals more than others. This discovery may lead to a comprehensive theory explaining most cases of high blood pressure.
Researchers found that treating vascular risk factors can help slow memory decline and reduce the risk of developing dementia. Those receiving full treatment were 39% less likely to develop Alzheimer's disease compared to those receiving no treatment.
A study reveals growing disparities in stroke death rates between European countries, with some nations experiencing a significant increase in mortality rates. The research suggests that controlling high blood pressure is crucial to addressing this public health issue.
Researchers from Wisconsin and Texas have identified two EET analogs that effectively lower blood pressure and reduce kidney injury in animal models of hypertension. The findings offer a promising avenue for the development of novel treatments for cardiovascular disease.
The Experimental Biology 2011 conference showcased cutting-edge research in biochemical battle of the bulge, DNA replication, and bone health. Researchers presented findings on obesity, cancer, and gene therapy, highlighting the importance of understanding cellular processes in disease prevention.
The Rheos System, a device that regulates blood pressure like a pacemaker regulates heart rhythm, helped lower blood pressure by 33 points. This substantial drop could require up to five additional drugs to control difficult-to-treat hypertension in patients with resistant hypertension.
UT Southwestern researchers have identified a specific type of blood pressure medication that minimizes the effect of decreased blood flow and oxygen levels in muscles during exercise. This finding has implications for people with high blood pressure who may stop exercising due to fear of heart attack or stroke.
A case study reports that singing lowered a 76-year-old woman's blood pressure from 240/120 mm Hg to acceptable levels for knee replacement surgery. The patient's blood pressure remained lower after continued singing for several hours, and she was cleared for successful surgery.
Researchers used catheter-based renal denervation to treat resistant hypertension in 106 adult patients, achieving significant reductions in systolic and diastolic blood pressure after six months. The treatment has shown efficacy in lowering blood pressure and may have applicability in managing other diseases such as heart failure and ...
A third of patients with resistant hypertension were found to have 'white coat' hypertension during ambulatory monitoring. The study suggests that those with true resistant hypertension show high blood pressure at work and during the night, but their cardiovascular outcomes are better than previously thought.
Researchers examine if lowering blood pressure reduces kidney disease progression in a federally funded study. About half of the 100 patients will have their systolic pressure below 120 to measure its impact.
Researchers found that Americans experience higher rates of chronic disease and markers of disease than their English counterparts at all ages, despite the US having a higher healthcare spending. The study suggests that allocation of health care resources, lifestyle, and social conditions may play a role in the observed differences.
A study found that patrons of black-owned barbershops who received regular blood pressure measurements and encouragement from barbers were nearly nine times more likely to see a physician than those who only received hypertension literature. The intervention led to a significant increase in men controlling their hypertension, with rate...
A new blood pressure measurement device using CASP has been developed to provide more accurate readings than current methods. The device, invented by scientists at the University of Leicester and HealthSTATS International, measures pressure close to the heart, leading to better treatment decisions and patient outcomes.
A new adherence course significantly improves blood pressure management in patients with high blood pressure, reducing non-adherence rates and blood pressure levels.
The SCAST study found that candesartan did not reduce the risk of vascular death, stroke, or heart attack in patients with acute stroke and high blood pressure. In fact, it increased the risk of poor outcomes and low blood pressure-related symptoms.
Researchers found that two genetic mutations can trigger hypertension in severe cases, affecting up to one-third of patients with a common cause. The mutations affect potassium channels and aldosterone release, leading to adrenal tumor formation and severe high blood pressure.
Researchers have found a genetic cause for benign hormone-producing tumours in the adrenal gland that lead to high blood pressure. The mutation affects a potassium channel, resulting in excessive aldosterone production and elevated blood pressure.
Acute ischemic stroke hospitalizations have declined among middle-aged and older individuals, but risen among those under 35, according to a study by the CDC. The rate of decline was greatest for girls aged 0-4, with a 51% decrease in hospitalizations.
A recent study published by the American Heart Association found that consuming diet soda daily can increase the risk of vascular events by 61% compared to non-soda drinkers. High salt intake, independent of hypertension, was also linked to a doubled risk of ischemic strokes.
A systematic review found that using a generic blood pressure and heart drug, losartan, instead of branded candesartan could save the UK National Health Service (NHS) £200 million in 2011. This is based on 2009 prescribing figures for primary care alone, with potential savings even higher.
A study published in Proceedings of the National Academy of Sciences found that low doses of losartan improved the effectiveness of two nanotherapeutic approaches against several types of cancer. Losartan normalized the abnormal extracellular matrix of tumors, allowing for better delivery and efficacy of therapies.
A new study published in BMJ found that Pay-for-Performance does not offer benefits to patients with hypertension, despite significant administrative costs. The research analyzed data from over 500,000 patients and found no impact on stroke, heart attacks, or mortality rates.
Researchers discovered that deep brain stimulation can lower blood pressure in people with difficult-to-control high blood pressure. The treatment used electrical pulses to send signals to the brain, resulting in a significant decrease in blood pressure and allowing some patients to stop taking all their blood pressure medications.
A new study suggests that a storytelling approach can help African-Americans with hypertension control their blood pressure through diet and medication adherence. The approach, which involves recognizable community members sharing positive messages, was found to be effective in improving blood pressure control among patients.