Articles tagged with Hypertension
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Research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2012 found that home telemonitoring with pharmacist-led support improved blood pressure control in patients with uncontrolled high blood pressure. The study, which involved 450 patients, showed a significant reduction in blo...
Researchers have discovered a new class of malaria transmission-blocking compounds that work by inhibiting bumped kinase I, blocking the parasite's infectious stage. Genetic variation is also linked to high blood pressure, with researchers finding that inhibiting renin pathway activity can return blood pressure to normal levels.
A pioneering study found that increased maternal choline intake during pregnancy can decrease children's chances of developing hypertension and diabetes. The researchers believe choline alters gene expression patterns involved in cortisol production, potentially reducing stress-related diseases.
A new study challenges traditional risk factors for contrast-induced nephrotoxicity, finding that patients with history of renal disease, hypertension, and heart disease are at greater risk. In contrast, diabetes is not a significant predictor of reduced renal function.
Researchers found that teenagers with abnormally high uric acid levels were twice as likely to have high blood pressure. Elevated uric acid persisted even after adjusting for other factors, suggesting it may be an independent driver of high blood pressure.
A new study at the University of Rochester Medical Center found that fetal growth restriction, a potential cause of stillbirth, is less common in obese pregnancies. In contrast, slow-growing babies are more prevalent among normal-weight women. The researchers suggest that missed diagnoses may not be a major concern in obese pregnancies.
A newly launched clinical trial at URMC is testing whether lower doses of an established blood pressure medication can provide the same benefits as a standard dose, potentially reducing side effects and costs. The study aims to learn how varying amounts of the medication affect patients with mild hypertension.
Researchers found that moxonidine, a second-generation anti-hypertensive drug, can improve heart function and survival without affecting blood pressure in an animal model. The study also showed the drug's beneficial effects on oxidative stress and insulin resistance.
A new Harvard report presents preliminary data showing that taxing salt products or implementing industry reductions can lead to significant reductions in cardiovascular disease deaths. The study found that these strategies could save money by reducing healthcare costs associated with hypertension and CVD events.
A 25% increase in high blood pressure screening in 19 developing countries could reduce CVD events and deaths by up to 3%. The study found that only one-third of people with high blood pressure are aware of their condition, and even fewer receive treatment.
A new study presented at the World Congress of Cardiology found that high normal blood pressure becomes less of a risk factor for incident cardiovascular disease and coronary heart disease with age. The study showed similar risks for diagnosed high blood pressure across all age groups.
The Society for Experimental Biology and Medicine (SEBM) has awarded ten young investigators for their groundbreaking research in the field of biomedical sciences. The awardees include Jie Xie and Zachary Berwick from Indiana University, who investigated human adipose-derived stem cells and coronary microvascular dysfunction respectively.
A review of 29 clinical trials found that taking an average of 500 milligrams of vitamin C daily reduced blood pressure by 3.84 millimeters of mercury in the short term. However, more research is needed to understand its implications as a treatment for high blood pressure.
A recent study published at the World Congress of Cardiology found that regular exercise significantly reduces the risk of death from cardiovascular disease in individuals with high blood pressure. The study involved over 434,000 participants and revealed a significant difference in mortality risks between physically active and inactiv...
A Swedish study found that consuming low-fat dairy products reduces the risk of stroke in adults. Low-fat dairy foods are rich in vitamins and minerals such as calcium, potassium, and vitamin D, which may help lower blood pressure and reduce the risk of ischemic stroke.
A recent study published in the European Heart Journal found that RAAS inhibitors significantly reduced all-cause and cardiovascular mortality in patients with high blood pressure. The treatment was shown to have a beneficial effect on mortality, particularly for ACE inhibitor users.
Researchers found that epigenetic mechanisms, such as reduced DNA methylation, contribute to high blood pressure and increased susceptibility to forming blood clots in pregnant women with preeclampsia. Inhibition of thromboxane synthase or dietary supplementation with folate may provide potential treatments for this condition.
Researchers found that small arteries showed signs of artery damage and reduced compliance after just six weeks on a high-fat diet, while large arteries remained unaffected. This early stage of damage may be the first step in developing high blood pressure.
Researchers found that over 68% of participants failed to take medication daily, with young men who smoke and drink alcohol being the least likely to follow treatment. High rates of hypertension remain steady in the region, contrary to Western Europe's decline.
A study found that moderate isoflavone intake can lower systolic blood pressure in young adults, with a notable benefit for African Americans. Isoflavones may help compensate for endothelial dysfunction, a condition that plays a bigger role in hypertension in African Americans.
Internet-based telemedicine systems lead to more timely treatment decisions and medication adjustments for patients with high blood pressure. Patients who reported frequent blood pressure readings via a web-based portal received more appropriate pharmacotherapy and an overall reduction in cardiovascular risk.
Research found that selective serotonin re-uptake inhibitor antidepressants may increase the risk of pregnancy-induced hypertension by 60%, with one SSRI associated with an 81% increase. Women should consult their doctor if concerned, as discontinuation can lead to depressive relapses and post-partum depression.
Researchers at Cleveland Clinic discovered that corin enzyme deficiency in the uterus may be an underlying cause of pre-eclampsia. The study found that many patients with pre-eclampsia had low levels of corin and identified corin gene mutations.
A study published by the American Heart Association found that orthostatic hypotension may be associated with a higher risk of developing heart failure, particularly in individuals aged 45-55. High blood pressure was also found to contribute to this association.
A study led by UCSF researchers found that women with mild retinopathy are more likely to experience cognitive decline and related brain changes. The findings suggest retinopathy could serve as a simple eye screening tool for detecting early stages of vascular disease.
Prolonged space travel has been found to cause brain and eye abnormalities in astronauts, similar to those seen in intracranial hypertension of unknown cause. MRI scans revealed optic nerve expansion, eyeball flattening, and pituitary gland changes in astronauts exposed to microgravity for extended periods.
Research suggests that T cells play a role in stress-dependent hypertension, and that medications targeting the immune system may also help control anxiety disorders. Mice studies found that T cell deficiency led to reduced blood pressure sensitivity to stress.
A study found that consuming 2-3 small purple potatoes per day reduces blood pressure by 4% without causing weight gain. This effect is attributed to the high levels of antioxidant compounds in these potatoes, which may have similar effects to ACE-inhibitor medications.
Researchers found that systolic blood pressure above 140/90 is associated with increased risk of end-stage renal disease in patients with chronic kidney disease. The study's findings challenge current guidelines, which recommend a systolic pressure of 130/80 or lower.
A study in PLOS Medicine found that tobacco smoking and high blood pressure account for the majority of deaths among Japanese adults. Reducing exposure to these risk factors could extend life expectancy by 1.4 years, according to researchers.
A new study by NYU School of Medicine reveals that positive affirmation, combined with patient education, improves medication adherence rates among hypertensive African-Americans. The study found a 22% increase in adherence rates among participants who received the intervention.
A randomized controlled trial found that patient education plus positive-affirmation induction and self-affirmation improved medication adherence in hypertensive African-Americans compared to patient education alone. The PA group had a 42% medication adherence rate at 12 months, whereas the PE group had a 36% rate.
Researchers discovered a common mechanism regulating blood pressure in humans through a sweeping genetic analysis of a rare disease. The study identified two genes interacting to control salt and potassium balance in the kidney.
A rare kidney disease study reveals how sodium and potassium levels are moderated in the body, shedding light on hypertension and familial high blood pressure disease. Researchers identified novel mutations linked to increased sodium activity and decreased potassium activity, providing a better understanding of this inherited condition.
Researchers at Boston University School of Medicine debunked the concept that excess salt causes high blood pressure by stimulating the sympathetic nervous system to produce adrenalin, causing artery constriction. The study suggests that diuretics may not be enough to treat hypertension cases associated with renal failure and recommend...
Researchers found that delaying effective hypertension treatment for up to a year results in small-quality adjusted life expectancy loss, but longer delays cause significant damage. The study suggests patients and providers focus on diabetes self-management and lifestyle modification within the first year after diagnosis.
A new study led by Patricia Coogan found that cumulative levels of nitrogen oxides increase the risks of type 2 diabetes and hypertension in African-American women. Exposure to particulate matter also showed a significant association with increased risk, but evidence was weaker.
A new study from Northwestern University finds that a significant increase in blood pressure during middle age increases the risk of heart attack or stroke. Maintaining low blood pressure early on can reduce this risk, with those who keep their blood pressure low having a significantly lower risk.
Researchers have discovered a molecular pathway that can help reduce cardiac damage caused by an enlarged heart, a common result of hypertension or a heart attack. The pathway, activated by stretch of adult cardiac cells, promotes the release of VEGF, which protects cardiac function and keeps cells alive.
Inaccurate blood pressure measurements from faulty techniques result in misclassified patients and potentially different treatment decisions. A study published by the University of New Mexico found that 93% of patients have different blood pressure readings when using outdated versus updated guidelines.
A recent study has found that nearly a third of children with sickle cell disease have suffered silent strokes, highlighting the need to identify early signs of anemia and high blood pressure. Researchers believe anemia is the key factor contributing to these risk silent strokes.
Scientists from Max Planck Institute discover gene SLC4A5 responsible for sodium dysregulation and hypertension. The study found that a genetic defect in this gene can lead to excessive renal retention of sodium and water, resulting in abnormal blood pressure levels.
Researchers found that more than one-quarter of Canadian adults will be diagnosed with hypertension by 2012/13. Higher rates were observed in women older than 65 and in the Atlantic provinces.
A mid-pregnancy test can predict preeclampsia, a late-pregnancy disorder characterized by high blood pressure and excess protein in the urine. Women with high blood pressure during pregnancy are at increased risk of experiencing high blood pressure, kidney problems, and stroke later in life.
A study co-authored by University of Leicester expert identifies key genetic mechanisms controlling blood pressure, including two microRNAs that regulate renin hormone production. This breakthrough could lead to innovative new treatments for high blood pressure.
A recent study by the National Institutes of Health has discovered a correlation between high blood pressure and stroke risk factors with cognitive impairment. The research, which followed over 30,000 participants, found that age, left ventricular hypertrophy, and high blood pressure were independent predictors of cognitive decline.
A new study published in Neurology found that a person's stroke risk profile can also predict their risk of developing memory and thinking problems later in life. The researchers followed 23,752 people with an average age of 64 and found that those with higher stroke risk profiles were more likely to develop cognitive problems.
Research suggests a link between high blood pressure and reduced ability to recognize emotional faces and texts, potentially causing miscommunication and increased distress in social situations. This 'emotional dampening' can lead to distrust, risk-taking behavior, and worsened mental health conditions.
A study by the American Society of Nephrology found that taking blood pressure-lowering medications at bedtime improves blood pressure control and reduces the risk of heart problems. Patients who took their medications before bed had better outcomes than those who took them in the morning.
A study by Heart and Stroke Foundation researcher Dr. Robert Nolan found that e-counselling led to a twofold decrease in blood pressure levels compared to those who didn't participate, improving lifestyle and quality of life.
A UBC study found that Black Canadians with darker skin are more likely to report poor overall health compared to those with lighter skin. The study suggests that colourism can negatively affect health and highlight the importance of considering racial identity mismatches.
A new study found that middle-aged women with Restless Legs Syndrome are at a higher risk of developing high blood pressure. The study, published in the American Heart Association journal Hypertension, found that women who experienced more frequent symptoms of RLS were more likely to have high blood pressure.
Researchers at Oregon Health & Science University discovered that calcineurin inhibitors spurs the production of a natural protein in the kidney, leading to hypertension. A thiazide diuretic drug blocks this protein, reducing hypertension in mice and showing promise for transplant patients with similar issues.
A study by the University of Manitoba and the Manitoba Metis Federation found a 25% higher stroke rate among Metis compared to other Manitobans. The research identified a link between Metis-specific health issues, such as smoking, diabetes, and high blood pressure, which increase stroke risk.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found a link between shift work and increased cortisol levels. This association was discovered in individuals working shifts at a young age and may contribute to cardiovascular risk.
A randomized controlled clinical study demonstrated that RESPeRATE can significantly relieve symptoms of heart failure in elderly patients. After 4 weeks of twice daily treatment sessions, patients showed a reduction in the severity of CHF measured by NYHA classification and dyspnea.
Research from the University of California - San Diego School of Medicine found that people with prehypertension have a 55% higher risk of experiencing a future stroke than those without. The study analyzed 12 prospective cohort studies involving over 518,000 participants and found that even high-but-normal blood pressure elevates stro...
A large study found that high blood pressure is associated with a higher risk of developing cancer and dying from the disease, particularly in men. The study analyzed data on blood pressure and cancer incidence and death in over 289,000 participants.
Kidney damage allows detrimental enzymes to wreak havoc on fluid balance, causing protein in the urine, high cholesterol, and swelling. New insights reveal that plasminogen plays a role in activating the epithelial sodium channel (ENaC), leading to excessive sodium absorption and water retention.
Research reveals that a high-salt diet and obesity trigger abnormal activation of the Rac1 protein in kidney cells, leading to increased blood pressure. This finding offers a potential new therapeutic target for treating salt-sensitive hypertension.