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JCI early table of contents for Jan. 25, 2013

Researchers found that stress accelerates prostate cancer development in mice, while a genetic mutation in the NESP4 gene disrupts a cellular complex essential for hearing. Combining green tea extract with vardenafil enhances anti-cancer effects in a mouse model of multiple myeloma.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 25, 2013

Hypertension during pregnancy increases risk of end-stage renal disease

A study published in the Canadian Medical Association Journal found that women with hypertensive disorders during pregnancy are at higher risk of chronic kidney disease and end-stage renal disease. The study analyzed data from over 26,000 women in Taiwan and found an increased risk of end-stage renal disease among those with preeclamps...

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateJan 22, 2013

No elevated 10-year risk of heart disease for people who become ill during a large E. coli outbreak

A new study published in Canadian Medical Association Journal found no elevated 10-year risk of heart disease for people who became ill during the Walkerton E. coli O157:H7 outbreak. The study involved 898 adults who consumed polluted drinking water and monitored their cardiovascular health over time.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateNov 19, 2012

Automated calls help patients in under-developed countries manage blood pressure, U-M study finds

A University of Michigan study found that automated calls and home blood pressure monitoring can significantly reduce blood pressures and depressive symptoms among hypertensive patients in Honduras and Mexico. The program showed promising results, especially among patients with limited literacy and income.

SourceMichigan Medicine - University of Michigan·JournalTelemedicine and e-Health·DateOct 31, 2012

Soccer scores a health hat trick for hypertensive men

Research from the University of Exeter found that soccer training significantly lowered blood pressure in middle-aged men with hypertension, improving exercise capacity and reducing body fat. The study suggests that regular soccer training can be a game-changing approach to managing cardiovascular disease risk.

SourceUniversity of Exeter·JournalMedicine & Science in Sports & Exercise·DateOct 15, 2012

UI research may help build a better drug

Researchers at the University of Iowa Health Care have discovered a new biological pathway that can be targeted to eliminate or reduce severe side effects of diabetes drugs. The study identified the Cullin-3 pathway as key to blood pressure-lowering effects, potentially leading to more specific and effective treatments.

SourceUniversity of Iowa Health Care·JournalCell Metabolism·DateOct 9, 2012

Starting to snore during pregnancy could indicate risk for high blood pressure, U-M study says

A new study from the University of Michigan found that women who start snoring during pregnancy are at increased risk for developing high blood pressure and preeclampsia. The research suggests that treating underlying sleep-disordered breathing may help mitigate up to 19% of hypertensive disorders during pregnancy.

SourceMichigan Medicine - University of Michigan·JournalAmerican Journal of Obstetrics and Gynecology·DateSep 25, 2012

Hypertension not so simple

Leading hypertension specialists recommend the inclusion of ambulatory blood pressure monitoring in national health surveys to accurately detect hypertension. This advanced diagnostic method can identify mitigating factors affecting diagnosis, such as white coat hypertension and nocturnal hypertension.

SourceElsevier Health Sciences·JournalJournal of the American Society of Hypertension·DateSep 25, 2012

Blood pressure diet works, but adherence drops among African-Americans

Researchers found that African-Americans are less likely to adopt the DASH diet due to cultural differences, but altering traditional recipes can improve adherence. Significant reductions in blood pressure were seen among participants who followed the DASH diet, especially when combined with exercise and weight loss.

SourceDuke University Medical Center·JournalJournal of the Academy of Nutrition and Dietetics·DateSep 19, 2012

LifeSkills training helps teens manage anger, lower blood pressure

A 10-week LifeSkills program improved teens' ability to control anger, decreased anxiety, and lowered blood pressures, with benefits holding up at six months. The program, adapted for adolescents, teaches assertiveness, sound decision-making, and positive interactions to reduce stress and improve overall well-being.

SourceMedical College of Georgia at Augusta University·JournalTranslational Behavioral Medicine·DateSep 10, 2012

Preeclampsia poses a significant long-term health risk according to new research from Ben-Gurion U.

Preeclampsia is a significant risk factor for long-term health issues, including chronic hypertension and hospitalizations. The study, published in the Journal of Maternal-Fetal and Neonatal Medicine, found patients with preeclampsia had higher rates of chronic hypertension diagnosed after pregnancy.

SourceAmerican Associates, Ben-Gurion University of the Negev·JournalThe Journal of Maternal-Fetal & Neonatal Medicine·DateSep 4, 2012

University of Illinois professor develops tool that helps dietitians deliver info clients need and can understand

A new algorithm developed by a University of Illinois professor helps dietitians determine a client's specific knowledge gaps, enabling them to focus on what the client needs to know. This tool addresses the challenge of inadequate pre-assessment of nutrition literacy among dietitians.