A study of 4,223 individuals found that subclavian artery stenosis is a significant risk factor for hypertension. Patients with peripheral arterial disease are five times more likely to have SS.
A recent report by NIST and RTI International estimates software difficulties in the construction industry have significant financial implications. The analysis breaks down data exchange-related losses across design, construction, and operations stages, identifying barriers to improvement.
Professor Ken Donaldson proposes the creation of a new discipline, nanotoxicology, to study the potential harmful effects of nanoparticles. The importance of nanotechnology is debated, but its adverse impacts need to be studied to ensure sustainable development.
The study uses nearly 1000 SNPs to define the genetic and evolutionary types of several anthrax isolates, providing a critical step toward future detection of this potential public threat. The results also establish a model for other biothreat pathogens and common public health-related diseases.
A study published in Diabetes shows that six months treatment with Laszarin TM reduces heart size in diabetic patients and reverses heart failure. The research led by Protemix demonstrates that defective copper metabolism is implicated in the development of heart disease.
A new process, Organ Recovery Systems, preserves transplant tissues/organs at refrigerator temperatures and minimizes damage from ice crystals. This technique reduces toxicity of cryoprotectants and enables long-term storage, potentially increasing organ availability worldwide.
NASA's TOPEX/Poseidon and Jason-1 satellites offer near-real-time lake water height data for 350 of the world's largest lakes. The US Department of Agriculture uses this information to manage irrigation and forecast crop production, particularly in areas with limited access to traditional water level gauges.
A new microfluidic device developed by NIST researchers can be used to make specialty polymers in small amounts or rapidly change polymer ingredients. This allows for systematic analysis of the impact of expensive additives on material behavior, which is crucial for applications in nanotechnology and biotechnology.
The Azithromycin and Coronary Events Study (ACES) found no reduction in cardiovascular events among participants treated with azithromycin. The study suggests that Chlamydia pneumoniae may not play a significant role in the late-stage development of coronary heart disease.
The landmark PROVE IT-TIMI 22 trial found that a long-term regimen of antibiotics designed to kill Chlamydia pneumoniae does not reduce the risk of heart attacks or cardiovascular disease. Researchers recommend focusing on proven therapies like high-dose statin therapy and ACE inhibitors instead.
Researchers at McGill University have identified a new gene, beta1-integrin, that plays a crucial role in the growth and development of breast cancer. Blocking this gene's function has been shown to halt tumour proliferation and prevent tumours from growing.
The trial found that early and aggressive statin use can reduce the long-term incidence of heart attacks, death from heart attack, stroke or readmission to the hospital for a cardiac event. However, benefits only became evident longer term, with no differences in endpoints during the first four months.
Preschoolers' diets have improved with increased servings of fruits, vegetables, and dairy products, but also saw a rise in added sugar and juice intake over the past 21 years. Children with healthier diets are less likely to be sick or overweight.
The American Physiological Society (APS) has awarded over $140,000 to minority students pursuing careers in physiology. These Porter Physiology Fellows are conducting innovative research projects that aim to improve our understanding of various physiological processes.
A study published in The Journal of the American Medical Association found that treating patients with recent acute coronary syndromes with higher doses of statins soon after experiencing heart-attack symptoms leads to a reduction in subsequent death, congestive heart failure, and other cardiac events compared to delayed treatment with...
The PNNL lab will develop a 'pulmonary physiome', a web-based model that provides predictive tools to understand the impact of airborne contaminants on human health. This project aims to improve treatments for asthma and other respiratory ailments.
A mouse study has identified a potential genetic link between NPAS3 and NPAS1 genes and psychosis. The mutated mice displayed deficits consistent with schizophrenia, including impaired social interaction and startle response. Further research is needed to confirm the connection.
A DNA mutation called 8-oxoguanine can evade detection by DNA replication enzymes, allowing it to persist in the DNA strand and potentially lead to stable incorporation of a lethal mutation. This discovery sheds light on how oxidative lesions affect DNA replication and has implications for cancer risk.
The European Society of Cardiology provides recommendations for athletes with cardiovascular disease, balancing risks and benefits of competitive sport. The panel aims to inform physicians and cardiologists about safe sport activities for candidates with cardiovascular abnormalities.
A recent study found that immediate statin therapy in hospitalized heart attack patients significantly reduced the risk of death and additional heart attacks. The study, which involved 3,605 patients at 260 medical centers, confirms earlier findings that early statin treatment is beneficial for heart health.
Researchers from MIT and international collaborations found that different proportions of two key ingredients in ginseng promote or hinder blood vessel growth, with implications for wound healing and cancer treatment. The study highlights the need for stronger regulations on herbal drugs due to variable processing methods.
Researchers discovered over 2,200 new human-specific Alu DNA repeats not found in chimpanzees, suggesting an explosive expansion of genetic code. This finding contradicts the idea of natural selection and highlights a chemical process driving human evolution.
The study group report emphasizes the need for systematic screening by 12-lead ECG to identify hypertrophic cardiomyopathy and other lethal cardiovascular diseases. The consensus document advocates for a common European screening protocol based on 12-lead ECG to prevent sports-related sudden death.
A new study suggests that early initiation of intensive statin treatment after a heart attack may lower the risk of future cardiovascular events. The research found that participants who received high-dose simvastatin had better outcomes than those on a placebo, despite an increased risk of muscle-related side effects.
The study characterizes lymphocyte microvilli, dynamic structures that alternate between assembly and disassembly. Disrupting these receptors could lead to a less toxic form of immune suppression and prevent metastasis in cancer cells.
Scientists have created a new technique to write nanometer-scale patterns onto surfaces, extending the capabilities of dip pen nanolithography. The thermal dip pen nanolithography (tDPN) method uses solid inks and special AFM probes with built-in heaters to control ink flow, allowing for precise patterning in vacuum environments.
Temple University professor Sergio Serrano has developed new mathematical procedures to solve complex, non-linear equations of water flow in soils. These techniques will help create more accurate models for flood forecasting and contaminant propagation predictions.
Matthew Bottomley, a researcher at the European Molecular Biology Laboratory, has won the 2004 EMBO Science Writing Prize for his captivating article on bioluminescent squid. The prize of 1,500 Euro will be presented to him at the EMBO Members Meeting in October this year.
A recent study by Scott W. Allard found that the welfare-to-work system is struggling to meet the needs of growing areas of poverty, which are increasingly geographically dispersed. The mismatch between service providers and populations in need may worsen under work-first welfare policies.
A new study highlights the long-term efficacy and safety of the angina drug nifedipine GITS, showing it can be used safely for the treatment of patients with coronary disease. The trial found similar mortality rates among those receiving the medication and a placebo, but lower incidence of heart failure and coronary interventions.
A new computational method developed by Widom and colleagues allows scientists to virtually predict the formation of amorphous metals and identify potential mixtures for metallic glass production. This approach has shown promising results in generating metallic glasses with remarkable corrosion resistance, strength, and elasticity.
African-Americans and Asians are less likely to trust the public health system's response to a bioterrorist attack. The UCLA study found that only 63% of African Americans and 68% of Asians/Pacific Islanders believe the system would respond fairly.
A study by University of Washington researchers found that people are less certain about the value of their time compared to money. Consumers tend to rationalize negative experiences when paying with time, but not when using hard-earned cash.
A new Web-based template helps Internet buyers and sellers with clear privacy policies, leading to increased trust and online sales. The study found that shoppers who used the template bought products 33% more often than those presented with standard policy statements.
Researchers have developed a simulation tool to predict the microstructures that form as complex liquid mixtures cool and solidify. The model accurately predicts how impurities and process differences affect crystal formation, enabling manufacturers to design new products with improved strength and durability.
A recent study by Mayo Clinic researchers suggests that patients with minimal or no disability after 10 years of multiple sclerosis (MS) are unlikely to progress and may not need medication. However, those with higher disability scores may still experience worsening symptoms over time.
Researchers analyzed the fruit fly's circadian rhythm to understand its complex dynamic behavior and hierarchical control scheme. They found that the system's architecture determines robustness and fragility, shedding light on how disease can be a failure of a robust biological system.
Researchers at NIST have developed a new method for studying ultrathin polymers, enabling the visualization of defects and structure. The technique uses near-field scanning optical microscopy to analyze the crystal structure and strain in thin-film crystals of polystyrene.
A study found that about 21% of middle-aged Americans have both high blood pressure and high LDL-cholesterol, significantly increasing heart attack risk. The combined effect was 51 cases per 10,000 person-years, much higher than expected.