A new urine-based test has been developed to detect kidney cancer, showing promising results in early diagnosis. The test identified gene changes in the urine of patients with kidney cancer that matched those found in tumor samples, indicating its potential as a diagnostic tool.
A new CT scan technique called multi-detector CT urography (MDCTU) has been shown to detect various urinary system problems, including bladder cancer, kidney stones, and cysts. The technique is more accurate than traditional methods and may be beneficial for high-risk patients.
BAY 43-9006 shows promise as a treatment for kidney cancer, with 42% of patients experiencing tumor shrinkage. The compound targets both Raf kinase and VEGFR2, inhibiting tumor growth and angiogenesis.
A phase II trial found that 42% of patients with metastatic kidney cancer experienced at least a 25% reduction in tumor size, with 6 patients experiencing a 50% or greater response. The study's innovative design validated a new approach to phase II trial design.
Researchers found that patients with smoking-related cancers had shorter telomeres than those without cancer, and that short telomeres were associated with a greater cancer risk. Smoking status significantly influenced the effect of short telomeres on cancer risk.
Researchers report successful treatment of 50 out of 51 renal tumors using radiofrequency ablation. The therapy is particularly effective for tumors on the outer surface of the kidney due to surrounding fat insulation.
Research suggests that diet is a second leading cause of cancer, accounting for approximately 30% of cancers in developed countries. A healthy weight, restricted alcohol consumption, and a balanced diet rich in fruits, vegetables, and cereals can help reduce cancer risk.
USC researchers propose lipid peroxidation as a mechanism for renal cell carcinoma, uniting known risk factors such as obesity and high blood pressure. The process creates DNA damage that can lead to cancer mutations, increasing kidney cancer risk.
Researchers at Rotterdam University Hospital develop genetically engineered T cells to target kidney cancer. The therapy combines the cellular immune system with the humoral immune system, offering a promising treatment option for patients with metastases.
A patient who developed kidney failure after taking Chinese herbal medicine containing aristolochic acid has now been diagnosed with kidney cancer. The authors warn of the carcinogenic potential of aristolochic acid in human beings.
A Mayo Clinic study finds that less radical surgery for kidney cancer is equally effective to radical alternative and less likely to cause failure in the second kidney. Long-term survival rates between the two procedures were identical, but patients undergoing less radical surgery had a lower risk of developing renal failure.
A Phase I/II study found substantial and occasional complete regression of widespread tumors in patients with treatment-resistant metastatic renal cell carcinoma treated with blood stem cell transplants. Three patients achieved total regression, while seven showed partial regression of disease.