Articles tagged with Myocardial Infarction
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A subgroup of high-risk patients with complex heart disease who took ticagrelor alone had fewer episodes of bleeding and no increase in heart attacks or stroke. Ticagrelor monotherapy significantly reduced clinically relevant bleeding without increasing the risk of additional heart attacks, strokes or death.
Two NIH-funded studies find that invasive procedures like stenting and surgery provide better symptom relief but not reduced risk for heart attack and death compared to medication and lifestyle changes. The trials followed over 5,000 patients with stable ischemic heart disease for three years.
A study of patients with diabetes found that taking ticagrelor alone reduced clinically relevant bleeding compared to combining it with aspirin, without increasing the risk of additional heart attacks, strokes, or death. The results were consistent across all types of diabetes patients.
A team of researchers has developed a groundbreaking 'cardiac patch with bioink' to repair heart damage. The patch uses genetically engineered stem cells and 3D bioprinting technology to enhance vascular regeneration and improve myocardiocyte survival. The innovative method has shown promising results in treating myocardial infarction.
Using radial artery instead of saphenous vein reduces death, heart attack and repeat revascularization procedures by 23-38%. Women benefit most from this approach. Further confirmation needed through larger randomized trial.
A statistical analysis predicts that a highly purified fish oil therapy could prevent thousands of cardiovascular events each year. The study used data from the National Health and Nutrition Examination Survey and showed a 25% reduction in cardiovascular events for patients with elevated triglyceride levels.
Research presented at the American College of Cardiology's Annual Scientific Session found that mental stress may be a stronger predictor of a repeat heart attack or dying from heart disease. Among over 300 young and middle-aged individuals, those who endured myocardial ischemia with mental stress had a two-fold higher likelihood of ha...
A study found that patients who listened to music for 30 minutes a day had lower levels of anxiety and pain, as well as reduced rates of certain heart conditions. Music therapy was more effective than standard treatment alone in reducing these symptoms.
A nationwide study found that bariatric surgery significantly reduces the risk of heart attacks and strokes among obese patients. The surgery was associated with a 60% lower rate of fatal and non-fatal heart attacks and stroke, as well as significant weight loss and improved type 2 diabetes management.
Researchers have uncovered mechanisms of healing after a heart attack using human cardiopoietic cells, which restored cardiac muscle to its pre-attack state. The study found that these cells reversed two-thirds of the changes caused by a heart attack, with 85% of cellular functional categories responding favorably to treatment.
A study of over 500,000 middle-aged adults found that anticholinergic burden is associated with an increased risk of future adverse events such as falls, dementia, heart attacks, strokes, and deaths. The use of multiple medications with anticholinergic properties can have cumulative negative effects on the body.
For most people, moderate to vigorous physical activity is beneficial to overall cardiovascular health. However, intense exercise programs like marathons and triathlons can raise the risk of sudden cardiac arrest, atrial fibrillation, or heart attacks, particularly in inactive individuals with known or undiagnosed heart disease.
A study published in the Journal of the American Medical Association found that genetic tests for heart disease risk had only modest improvement over conventional testing. The test analyzed thousands of genetic variants linked to heart health but did not significantly enhance predictive power.
A study published in Circulation shows that declines in heart attacks are greatest among men, with a nearly 50% decrease between 2000 and 2014. While women also experienced a decline, their rate slowed in the last five years of the study.
A new study found that exposure to ultrafine particles in air pollution may trigger a nonfatal heart attack within hours. The research, published in Environmental Health Perspectives, analyzed data from over 5,900 patients in Germany and found stronger effects on health with particle length and surface area concentrations.
A team of bioengineers from Trinity College Dublin has developed a prototype patch that mimics the electrical signalling properties and mechanical demands of heart tissue. The patch, manufactured via melt electrowriting, withstood repeated stretching and showed good elasticity, addressing key requirements for cardiac biomaterials.
Researchers analyzed data from over 49,000 adults and found that while overall smoking rates have decreased among Americans aged 20+, the rate of stroke survivors who smoke remains steady. The study emphasizes the importance of quitting smoking for stroke survivors, citing the highly addictive nature of nicotine.
Researchers analyzed data from over 300,000 people and found that genetics significantly increases the risk of stroke and heart attack in men compared to women. The study suggests that genetic scores could be used to identify healthy middle-aged adults at higher risk and develop preventive measures.
Preliminary research found that regularly golfing can lower the risk of death among older adults. Golfing was associated with a significantly lower rate of death compared to non-golfers, likely due to its benefits such as stress reduction and regular exercise.
Researchers at Oxford University have found a protein called Plexin D1 that detects disturbances in blood flow and triggers inflammation and plaque formation, leading to serious health problems. The discovery offers new hope for developing treatments to block plaques before they form.
Researchers at University of Oxford have identified a new target for repairing the heart after a heart attack by modulating the immune response. Macrophages play a key role in forming cardiac scars, and modifying their behavior could lead to more efficient repair and potentially avoid heart failure.
Researchers will analyze a database of anonymized GP consultations and medical records to identify shared characteristics among patients with undiagnosed chest pain who later experience a heart attack or stroke. The study's findings could inform GPs about warning signs, enabling early intervention and potentially preventing many cases.
Researchers have invented a Trojan Horse nanoparticle that selectively targets and eats away at plaque-causing cells, reducing plaque size and stabilizing it. This approach shows promise as a potential treatment for atherosclerosis, the leading cause of death in the US.
A large study of over 22,000 patients after a first heart attack found that abdominal obesity is independently associated with fatal and non-fatal heart attacks and strokes. Waist circumference was a stronger marker of recurrent events than overall obesity in men, while women had a U-shaped relationship between waist circumference and ...
A recent study published in the Journal of the American College of Cardiology found that approximately 2 million adults in the US who have cardiovascular disease currently use or have used marijuana. The review also reveals that cannabinoids can interact with drugs used to treat heart disease, increasing the risk of adverse effects.
A new radiotracer, 68Ga-FAPI-04 PET, can effectively image fibroblast activation after myocardial infarction, identifying a time window during which cardiac fibrosis can be prevented. This technology may aid in the clinical management of patients after a heart attack.
A new study has shown that a protein therapy called rhPDGF-AB can improve the quality of scar tissue after a heart attack, leading to the formation of new blood vessels and reduced rates of dangerous heart arrhythmia. The treatment has increased survival rates in animal models and holds promise for improving patient outcomes.
A new study by Oxford University Press USA reveals that machine learning can predict long-term risks of heart attack and cardiac death. The research used machine learning to assess cardiovascular risk factors in subjects, aligning accurately with actual events over a 15-year period.
A new national study found that walking and cycling to work were associated with a significant reduction in heart attacks. For women who walked to work, there was an associated 1.7% reduction in heart attacks the following year, while men who cycled to work experienced the same decrease.
A study published by the American Heart Association found that low-dose aspirin did not reduce the risk of a fatal heart attack among African Americans, unlike in white populations. The study used data from over 65,000 participants and suggested genetic differences and poor control of other risk factors may contribute to this result.
A $1 million international study aims to develop a new therapeutic treatment for people who have suffered heart attacks with extensive cardiac damage. The project, led by UniSA Professor Janna Morrison, explores whether changing the expression of a specific molecule can repair cardiac damage.
A new study suggests that taking aspirin daily to prevent a heart attack or stroke may no longer be recommended for adults without a history of these events. The study found that the potential benefits of aspirin are similar to its potential harms for most people, highlighting the need for personalized advice from doctors.
Researchers found that mice lacking an inflammation resolution sensor developed spontaneous obesity, heart disease, and shortened lifespan, indicating impaired inflammation resolution. This study sheds light on the sensor's integrative role in managing cardiometabolic health and inflammation-resolution processes.
Research reveals that only one LDL subclass causes significant damage, while others are harmless. Accurate diagnosis using LDL subclass composition could improve cardiovascular disease rates.
A study found striking disparities in in-hospital care and mortality between homeless and non-homeless adults hospitalized for urgent cardiovascular conditions. Homeless patients were significantly less likely to receive important diagnostic or therapeutic procedures and generally had higher in-hospital death rates compared to non-home...
Preliminary research found that men who maintained high levels of moderate to vigorous physical activity both before and after their heart attacks were 39% less likely to die from any cause. Regular physical activity after a heart attack is associated with better survival, even in older adults.
Patients who underwent metabolic surgery had a lower risk of developing systolic heart failure and dying from recurrent myocardial infarction compared to those without surgery. The study found significant cardiovascular benefits of metabolic surgery, emphasizing its potential as part of the treatment plan for patients with severe obesi...
Chronic kidney disease patients are at an increased risk of heart attacks, congestive heart failure, stroke, and other adverse cardiovascular events. The study found that chronic kidney disease is associated with a 95% higher risk of heart attack during the follow-up period.
A new blood test increased diagnoses of women with heart attacks by 42%, but the gender gap in treatment remains. Women were 50% less likely to receive recommended treatments after a heart attack diagnosis.
Researchers at Université de Genève and University of Lyon identified deoxydihydroceramide as the molecule causing tissue necrosis. Inhibiting its synthesis reduced tissue damage by 30% in mice, suggesting a new model for treating heart attacks and strokes.
A new study finds that dog owners have a lower risk of death from heart attacks and strokes, with significant reductions in mortality rates for those living alone or with a partner. Dog ownership is associated with increased physical activity, decreased depression, and reduced social isolation.
New research warns Canadians against taking daily aspirin for primary prevention due to increased risk of major internal bleeding and potential increase in cancer deaths. Experts recommend alternative preventive measures such as smoking cessation, exercise, blood pressure tracking, and considering the Mediterranean diet.
A recent international trial showed that patients requiring emergency heart attack treatment also benefit from further intervention to reduce the risk of future heart attacks. The study found that additional stenting for significant narrowings in other untreated arteries significantly reduces the risk of future heart attacks and death.
A new study based on SWAN data shows that frequent and persistent menopausal hot flashes are associated with a higher risk of heart problems. The study found that hot flashes at the beginning of the transition doubled the risk of clinical CVD events, while persistent hot flashes over 20 years increased the risk by 80%.
A recent study published in Nature Communications found that a circular RNA called circFndc3b plays a critical role in tissue repair after a heart attack. The RNA acts like a 'sponge' to bind harmful molecules, preventing cell death and promoting vascular growth, which aids the repair process.
Researchers at Vanderbilt University have developed an antibody to target cadherin-11, a major contributor to inflammation in cardiac fibrosis. The study shows that the antibody can fine-tune inflammation and reduce scarring, leading to improved cardiac function.
Researchers at Temple University Health System have identified a new target regulating mitochondria during stress, which could lead to a new approach to treating conditions such as heart failure, heart attack, stroke, and neurodegeneration. The discovery highlights the role of MCUB in mitigating calcium overload in injured heart tissue.
Researchers discovered that border zone cells in humans and mice develop a gene program that helps them survive a heart attack. This response is crucial for long-term recovery of the heart, but further research is needed to induce this response in humans.
A pre-clinical study published in Redox Biology reveals that vitamin E may help preserve heart function after a heart attack by reducing inflammation and oxidative stress. The findings suggest that vitamin E could be an effective and inexpensive therapy for patients with heart attacks, providing new hope for cardiovascular health.
A new study by researchers at Uppsala University found that attending Sweden's 'Heart School' program significantly lowers mortality risk for patients with a first heart attack. The program focuses on lifestyle-related risks and teaches patients the importance of healthy habits.
Researchers will examine biomarkers and chemicals in thirdhand smoke to understand its impact on cardiovascular health. The five-year study aims to design better therapies for thirdhand smoke-induced cardiovascular disease.
A new NIH-funded study found that hospital emergency room closures can adversely affect health outcomes for heart attack patients at neighboring hospitals. Conversely, when a new emergency department opens, health outcomes for those patients improve.
A new study projects a cost-effective polypill to be the standard of care for secondary prevention of cardiovascular disease, offering excellent clinical and health economic returns on investment. The polypill is expected to save lives and money by reducing medication burden and increasing patient adherence.
Researchers developed a 'fat fingerprint' using machine learning to identify inflammation, scarring, and changes to blood vessels. The new biomarker can predict heart attacks with higher accuracy than current tools.
A study of nearly 1.7 million 18-year-old boys found that higher body mass index (BMI) is linked to a greater risk of heart attack before age 65. The research suggests that monitoring BMI during puberty and preventing obesity with healthy eating and physical activity may help reduce this risk.
A new study of nearly half a million people found that sleeping between 6 and 9 hours nightly can cut the risk of heart attack by up to 18% for those with genetic predisposition. Sleeping too little or too much also boosts heart attack risk, with optimal sleep duration being critical for overall heart health.
A new study comparing heart attack care in Sweden and the UK found that patients in Sweden had lower mortality rates for both STEMI and NSTEMI forms of heart attacks. The results suggest improved outcomes due to increased use of invasive treatments and recommended medications in Sweden.
A new study published in the New England Journal of Medicine shows that opening all clogged arteries after a serious heart attack leads to a 26% reduction in patient risk of dying or having a recurrent heart attack. This approach also shows no major downside to additional procedures.
The European Society of Cardiology recommends reducing air pollution and environmental noise to minimize heart attack and stroke risk. Lifestyle changes, such as quitting smoking, eating a balanced diet, and exercising regularly, are also emphasized.
A study found that bacteria in coronary plaques were pro-inflammatory, whereas gut bacteria were diverse and varied. Patients with acute coronary syndrome had different gut microbiota compared to those with stable angina. The research suggests a possible role for microbes in plaque destabilization and heart attack onset.