Articles tagged with Myocardial Infarction
A study in mice reveals genes and metabolic processes that could aid or hinder recovery after a heart attack, with potential targets for treatments. The research used systems biology approaches to analyze gene activity across multiple tissues, identifying common and tissue-specific responses.
Research strongly links thin and brittle bones to increased heart attack and stroke risk in women. Thinning lower spine, top thigh bone, and hip were independently associated with a heightened risk, while osteoporosis was linked to a 79% higher cardiovascular disease risk.
A new study found that women with possible heart attacks are triaged less urgently, wait longer to be seen, and undergo fewer tests than men. Women were also less likely to receive cardiac monitoring or be seen by a consultant.
A study found that psychological distress after a heart attack doubles the risk of subsequent cardiac events in younger adults. Researchers also discovered an association between inflammation and cardiovascular risk among patients experiencing high distress.
A new phone-based app facilitated more efficient hospital intakes for patients with STEMI, leading to faster treatment times and reduced damage. The average time between EMS arrival and PCI was about 11 minutes shorter among cases where the app was used.
The study analyzed over 1,600 patients with STEMI during the COVID-19 pandemic and found that those with COVID-19 positive status had higher in-hospital mortality and were less likely to receive diagnostic angiograms. Additionally, patients of minority ethnicity and with diabetes had poorer outcomes.
A new study identifies three molecules in the blood that can distinguish between heart attack and chest pain caused by other conditions. The researchers hope to develop a simple blood test for early diagnosis, which could help doctors quickly confirm or rule out a heart attack.
Recent advances in understanding atherosclerosis have shifted traditional views on who is at risk for heart attacks and strokes, highlighting the importance of HDL cholesterol, triglycerides, and inflammation. This review paper explores these changes and their implications for treatment and prevention.
Researchers found that family history of premature heart attacks, strokes, or angina poses major risks to close relatives, with shorter survival times reported among those with first-degree relatives. The study suggests a complex interplay between genetic and environmental factors in cardiovascular disease.
A University of Gothenburg study found a significant increase in heart failure and stroke cases among men under 40 in Sweden, attributed to rising obesity rates and declining physical fitness. The study monitored over 1.2 million men for 20 years, revealing a sharp decline in heart attacks despite increasing obesity.
Scientists have discovered a critical new gene, Klf1, that plays a vital role in healing damaged hearts. The gene allows heart muscle cells to divide and multiply after injury, potentially leading to complete regeneration and healing of damaged tissue.
A study published in Chinese Medical Journal identified factors that predict patients with STEMI refusing PCI, including age, history of myocardial infarction, and heart rate. The findings suggest that healthcare providers may use these predictors to improve treatment compliance and outcomes for patients with STEMI.
A study found that young adults with inflammatory conditions like psoriasis, lupus, or rheumatoid arthritis are twice as likely to experience fatal heart attacks. Researchers also discovered that patients with these conditions were less likely to be prescribed aspirin and statins after a heart attack.
A prospective cohort study found that patients who work more than 55 hours per week are at a twofold increased risk of having a second heart attack. Long working hours were associated with higher job strain and poorer lifestyle risk factors, particularly among men and younger workers.
Men with stable coronary artery disease who take Viagra live longer and have lower risk of new heart attack compared to those treated with alprostadil. The study's findings suggest a dose-dependent reduction in cardiovascular events.
Researchers found that people with schizophrenia, bipolar disorder, or major depression are more likely to die within 30 days and one year after a heart attack. The study highlights chronic health inequalities faced by those with serious mental illness and calls for urgent action to address disparities.
A mouse study finds that treatment with MCB-613 repairs heart tissue after a severe heart attack, preventing damage and scarring. The molecule decreases inflammation and increases heart function, offering hope for effective treatments to prevent heart failure.
Researchers developed a new intravascular imaging technique, ILSI, which can detect unstable coronary plaques. The technique provides a direct assessment of mechanical stability, allowing for early detection and treatment of high-risk vulnerable plaques.
A study by the European Society of Cardiology found that vital exhaustion is associated with a higher risk of myocardial infarction in men. Symptoms of vital exhaustion include excessive fatigue, demoralization, and increased irritability, particularly in individuals experiencing prolonged exposure to psychological stressors.
A study found that women are more likely to experience delayed diagnosis and misdiagnosis of chest pain, which is a key symptom of reduced blood flow to the heart. Women were also less likely to be suspected of having a heart attack than men, with lower rates of probable acute coronary syndrome in females.
A new study by scientists at Temple University identifies a promising novel therapeutic strategy targeting G protein-coupled receptor kinase 5 (GRK5) in the heart. Reducing GRK5 levels improves survival following heart attack in mice, suggesting that GRK5 inhibition may be a viable treatment option for human patients.
Researchers discovered a new protein, Prosaposin, that plays a crucial role in atherosclerosis. The protein has an anti-inflammatory effect, which helps slow down the disease progression.
Research highlights increased depression risk after stroke compared to heart attacks, with female stroke patients facing a higher risk. Studies found that post-stroke depression affects up to a third of stroke patients and has poorer quality of life outcomes.
Researchers at Lund University developed a new examination method using NIRS and IVUS, which identifies high-risk plaques that cannot be seen with traditional angiograms. The study found that over 14% of treated patients experienced heart disease recurrence within four years, highlighting the importance of early detection and treatment.
Research presented at the American Stroke Association International Stroke Conference 2021 found that silent heart attacks may increase stroke risk in adults 65 and older. Participants who had evidence of a silent heart attack had a 47% increased risk of developing a stroke, compared to those without a silent heart attack.
A recent study published in Circulation shows that combining genetic risk with LDL cholesterol levels can accurately predict heart attack risk. The study reveals that individuals with a high polygenic predisposition for heart attack, regardless of their LDL level, are at increased risk.
Researchers have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a heart attack. The study found that timely injection of the hydrogel resulted in less fibrosis and an increase in new blood vessels, preserving cardiomyocytes and supporting functional recovery.
A study published by the European Society of Cardiology found that individuals who do not exercise have a higher risk of dying immediately from a heart attack. Regular physical activity was associated with a lower risk of instant and 28-day fatal heart attacks, with moderate to high levels of activity showing significant benefits.
NYU College of Dentistry has been awarded a $1.9 million NIH grant to study the molecular mechanisms underlying mitochondrial permeability transition, a phenomenon that causes tissue damage during strokes and heart attacks. The research aims to develop new drugs that can protect against cell death and tissue damage.
Researchers from the Hubrecht Institute mapped the recovery of the heart after a heart attack, highlighting the importance of cardiomyocyte communication in forming scar tissue. The study provides new insights into the complex process of heart recovery, shedding light on potential therapeutic targets to improve outcomes.
A Mayo Clinic study found that age influences sex-related outcomes after a heart attack, with younger women being more likely to experience vascular complications and major bleeds. The study analyzed over 6.7 million hospitalization records and showed distinct differences in risk profiles for heart disease between men and women.
Researchers found a sharp drop in hospital admissions for heart failure and heart attacks, approaching pre-pandemic levels. The decline may be linked to fear of contracting COVID-19, warning that delays can lead to life-limiting complications or death.
A new study found that implementing an 'opt-out' pathway for cardiac rehabilitation referrals significantly increased rates, from 15% to 85%, among patients eligible for the therapy. The opt-out system leveraged technology to automate the process, making it easier for clinicians and patients.
A new study found that people with abdominal aortic calcification (AAC) have a two to four times higher risk of future cardiovascular events. The more extensive the calcium buildup, the greater the risk.
A global study found that a difference in blood pressure readings between arms is linked to increased risk of heart attack, stroke, and death. The research suggests that measuring both arms could save lives by identifying patients at significantly increased risk.
A new study from University of Alberta researchers found that women are at a 20% higher risk of dying or experiencing heart failure after a heart attack compared to men. The study examined data on over 45,000 Canadians who were hospitalized for their first heart attack between 2002 and 2016.
A study suggests that COVID-19 guidance in Sweden led to reduced exposure to heart attack triggers such as stress and intense physical activity. The proportion of patients attending emergency cardiac angiography units dropped by 38% on days when people stayed close to home, indicating a potential reduction in heart attack risks.
A team of researchers at the University of South Florida has discovered that Sesn2 protein, which protects the heart from stress, diminishes in levels over time, weakening the heart and increasing the risk of heart attack. This finding holds promise for developing new therapeutic treatments to maintain healthy cardiac function.
A study using AI to analyze abdominal CT images found that visceral fat area is independently associated with future heart attacks and strokes. The analysis, which outperformed traditional BMI measures, may lead to more accurate cardiovascular risk assessments.
A study found that lab results for adults with obesity are similar to those of their leaner counterparts, contradicting one theory behind the 'obesity paradox'. Instead, researchers suggest that unconscious bias in healthcare providers may lead to better outcomes for obese patients in critical care
Researchers analyzed data on over 45,000 patients hospitalized for their first heart attack between 2002-2016. The study found that women were older and faced more risk factors than men, which put them at a higher risk of developing heart failure after a heart attack. Women also had lower rates of prescribed medications and revasculari...
Researchers at Baylor College of Medicine have discovered a potential treatment for heart failure after a significant heart attack. MCB-613, a small molecule stimulator, has been shown to decrease damaging remodeling and inhibit the development of heart failure in mice.
A new study by UC San Francisco researchers found that California's Black and Hispanic communities received less benefit from regionalized heart attack care protocols. Despite improved access to PCI-capable hospitals, survival rates remained unchanged for minority groups, whereas whites in non-minority communities showed better outcomes.
A daily dose of omega-3 fatty acids failed to reduce cardiac events, including secondary heart attacks and strokes, among elderly people who survived a recent heart attack. The OMEMI Trial found no significant difference in the rate of cardiac events between the two groups after 2 years of follow-up.
Researchers found that additional imaging tests revealed hidden causes of heart damage and inflammation in 84% of women with MINOCA, a type of non-obstructive coronary artery disease. The study suggests that women are more likely to have this condition than men, and it has the potential to guide medical therapy for secondary prevention.
The ALPHEUS trial found no significant difference in periprocedural heart attack and complications between ticagrelor and clopidogrel in patients undergoing elective PCI. The study suggests that ticagrelor should be reserved for acute coronary syndrome cases, not those with stable heart conditions.
A new screening questionnaire can predict individuals at high risk of coronary artery disease, according to a Swedish study. The questionnaire uses data easily measured at home and is successfully imaged using CCTA images to examine patients' arteries for the presence of plaque.
A study published in the European Journal of Preventive Cardiology found that nearly half of type 2 diabetes patients are at very high risk of fatal events within a decade. Lifestyle advice, including quitting smoking, healthy diet and regular exercise, is recommended to prevent cardiovascular disease.
A study published by investigators at Massachusetts General Hospital reveals that patients with type 2 myocardial infarction often receive inconsistent care. The research indicates that patients evaluated by cardiologists are more likely to undergo stress tests and heart imaging exams, and have higher rates of follow-up cardiology visits.
Two studies suggest that older adults aged 70 and over with elevated LDL cholesterol levels have the highest incidence of heart attacks and cardiovascular diseases. Cholesterol-lowering therapies, including statins, are as effective at reducing cardiovascular events in this age group as they are in younger people.
Studying arterial deposits, researchers found that activated immune cells accumulated on the interior arterial wall, causing damage to the arterial lining. This discovery suggests a misguided adaptive immune response is involved in heart attacks, holding promise for personalized treatments and prevention of clinical complications.
Two studies presented at the American Heart Association's Scientific Sessions 2020 found that marijuana use is associated with a higher risk of stroke and post-procedure bleeding after PCI. However, marijuana smokers also experienced a decreased risk of acute kidney injury compared to non-users.
A study presented at the American Heart Association's Scientific Sessions 2020 found that women veterans with PTSD have a 44% higher risk of developing ischemic heart disease compared to those without PTSD. The increased risk was most prominent in younger women, especially those under 40 years old.
A new study suggests that aspirin use is most beneficial for individuals with high coronary calcium scores and a low risk of bleeding. The research found that for patients with CAC scores above 100, aspirin's benefits outweigh its risks, but this effect only applies to those with inherent low bleeding risks.
Researchers developed a cardiac patch with engineered blood vessels that improved recovery from myocardial infarction in rats and pigs. The patch promoted cardiac muscle and blood vessel growth, reducing scar tissue and inflammation.
Researchers found that weight-reduction surgery significantly reduces the risk of a second heart attack, cardiovascular event, and death among severely obese patients with a prior heart attack. Patients who underwent surgery also experienced improvements in sleep apnea, hypertension, cholesterol, and Type 2 diabetes.
A nationwide cohort study found that severely obese individuals who underwent gastric bypass or sleeve procedure had a lower risk of additional myocardial infarctions and improved survival rates. The study suggests that metabolic surgery may have a positive impact on cardiometabolic risk factors beyond weight loss.
A recent study published in the European Heart Journal - Acute Cardiovascular Care reveals that one in five high-risk patients undergoing major non-cardiac surgery will develop one or more heart complications within a year. The study found that patients are at risk for a longer period than previously thought and that measuring troponin...
Extracellular vesicles (EVs) derived from endothelial cells have been shown to revive heart cells after a heart attack and keep them functioning while deprived of oxygen. The researchers demonstrated this functionality in human tissue using a heart-on-a-chip model.
A new study published in JAMA Cardiology found that 30,000 out of every 100,000 stress tests performed each year were unnecessary for patients undergoing knee and hip replacement surgeries. Despite a decrease in overall stress testing since 2006, the study highlights the need for educational initiatives to improve the utilization of me...