Articles tagged with Myocardial Infarction
Researchers found that carprofen pretreatment before experimental heart attack in mice impairs the resolution of acute inflammation after cardiac injury. This leads to a non-resolving inflammation characterized by an amplified CD47 marker on neutrophils, which resists clearance and triggers more inflammatory responses.
Researchers at the University of Würzburg have made a breakthrough in treating myocardial infarction, with stem cells found to exist in vascular walls and intracardiac blood vessels. These cells may be able to regenerate damaged cardiac muscle tissue in response to heart attacks.
A large Taiwanese study found that patients with sepsis are at increased risk of cardiovascular events, including stroke and heart attack, within the first 4 weeks after hospital discharge. Younger patients with sepsis aged 20 to 45 years were particularly at higher risk.
Scientists at Baker Heart and Diabetes Institute have identified plasma lipid biomarkers that improve upon traditional risk factors in predicting heart disease and stroke. The new blood test will use up to ten lipid markers to better diagnose heart disease, reclassifying patient risk and guiding treatment.
A study found that firefighters who died from cardiac arrest were more likely to have narrowed arteries, an enlarged heart, and increased wall thickness of the left ventricle. These conditions increase the risk of death from cardiac arrest, highlighting the importance of medical screening for firefighters.
A new study found that walking more can significantly lower the risk of heart failure in older women, particularly those with reduced ejection fraction. Increased physical activity was associated with a 9-10% risk reduction for heart failure and its subtypes.
Researchers found that an antioxidant called apocynin can cut plaque buildup in half and lower inflammation to pre-attack levels. This treatment could help reduce the risk of a second heart attack or stroke, particularly in mice that have experienced a first attack or stroke.
A large-scale study found that diclofenac, a common painkiller, is associated with an increased risk of major cardiovascular events such as heart attack and stroke. The study suggests that diclofenac should not be available over the counter and when prescribed, should come with a warning about its potential risks.
Researchers at Tokyo Institute of Technology developed a fluorescent protein sensor that can provide real-time information on dynamic changes in oxygen levels. The ANA sensor shows very high sensitivity in tracking changes in oxygen content.
A large study of Australian adults found that psychological distress was linked to a higher risk of heart attack and stroke. The researchers estimated that among women, high/very high psychological distress was associated with a 44 percent increased risk of stroke.
A new study suggests that a heart-healthy diet may consist of foods previously thought to be detrimental, such as dairy products and meat. The research, which analyzed data from over 218,000 people across five continents, found that consuming these foods was associated with lower risks of cardiovascular disease and death.
The VERDICT trial found that postponing invasive examination and treatment for up to 72 hours is as good as a very early approach in patients with NSTE-ACS, particularly those with high risk. This contradicts ESC guidelines on immediate versus early invasive strategies.
A new randomized trial tested a revised set of criteria for diagnosing heart attacks, but found that using these criteria did not reduce the rate of recurrent heart attacks or cardiovascular deaths. The study suggested that the revised criteria could lead to more diagnoses and treatment, but with no adverse effects on patient outcomes.
A recent study published in the New England Journal of Medicine found that lorcaserin, a weight loss drug, helped patients lose weight without increasing the incidence of heart attacks, strokes, and death from heart disease. The trial involved 12,000 overweight or obese patients at risk for cardiovascular events.
The trial found that using two arterial grafts, including internal thoracic and radial arteries, may provide better outcomes than a single graft. However, the results are not conclusive due to high rates of deviations from randomization.
Research presented at ESC Congress 2018 found that impaired mental status is associated with a doubled risk of death one year after a heart attack in elderly patients. Cognitive impairment was detected in 29% of patients and was linked to higher risks of bleeding complications, rehospitalisation, and death.
The ARRIVE study found that daily aspirin use did not reduce cardiovascular events, but participants who took aspirin had fewer heart attacks. Aspirin reduced the risk of total and nonfatal myocardial infarction in certain age groups, but increased gastrointestinal bleeding rates.
The 2018 Fourth Universal Definition of Myocardial Infarction provides clarity on diagnosing a heart attack, distinguishing between myocardial infarction and myocardial injury. Elevated troponin levels are not sufficient for diagnosis, and oxygen shortage detection via electrocardiogram is crucial.
A new study suggests that incorporating heart scans into routine care could save thousands of lives in the UK. The SCOT-HEART study found that patients who received a computed tomography angiogram (CTA) scan had a 40% lower risk of heart attack within five years.
A new study published by the European Society of Cardiology has investigated the major cause of heart attacks in women, finding that spontaneous coronary artery dissection (SCAD) is a leading factor. The study also identified emotional stress as a key trigger for SCAD, which can lead to narrowing, aneurysms, or tears in the arteries.
Research suggests that very high HDL cholesterol levels may increase the risk of heart attack and death, contrary to traditional views. The study found a U-shaped curve in the relationship between HDL cholesterol levels and cardiovascular risk, with both low and extremely high levels increasing the risk.
Researchers are developing a biodegradable and bioactive hydrogel material that can be injected into the heart to promote cardiac repair after a heart attack. The goal is to significantly increase stem cell recruitment, accelerate cardiac repair and improve cardiac function.
The study found that state Medicaid expansions under the Affordable Care Act led to a decline in uninsured hospitalizations for major cardiovascular events. Cardiovascular disease is a leading cause of death in the US, and this study examined the association between Medicaid expansion and changes in uninsured hospitalizations.
A new analysis found that daily e-cigarette use nearly doubles the odds of a heart attack, with dual use of e-cigarettes and conventional cigarettes increasing the risk five-fold. Quitting either product can reduce this risk.
A simple laboratory score has been developed to diagnose patients with heart attack symptoms, reducing the number of blood tests and time spent in emergency departments. The score can identify patients at risk of subsequent heart issues after discharge.
A study of 300,000 type 2 diabetes patients found that those with controlled risk factors had a significantly low risk of premature death, heart attack, and stroke. Optimizing medication, not smoking, and managing other risk factors can greatly reduce the risk.
A large international study found that individuals consuming average amounts of sodium (3-5g/day) do not face increased health risks. However, those exceeding five grams a day may experience cardiovascular events, and improving dietary quality with potassium-rich foods can mitigate this risk.
A 19-year review of nearly 582,000 heart attack cases reveals that female patients have a significantly higher survival rate when treated by women doctors. The study's findings also suggest that male doctors with more female colleagues in the ER can improve survival rates for female patients.
A study of over 500,000 observations found that female heart attack patients treated by male physicians had lower survival rates. Survival rates improved when there were more female physicians in the emergency department or when male physicians were exposed to more female patients.
A new high-sensitivity blood test for cardiac troponin has been found safe and effective in diagnosing heart attacks faster than traditional methods. The test ruled out heart attack in 30-83.8% of patients within three hours, compared to 80.4% with conventional testing.
Researchers developed a drug-delivery system that dissolves clots in minutes, limits scarring, and preserves cardiac function. The targeted treatment may improve patient outcomes by allowing for earlier treatment of heart attacks without surgical intervention.
A review published in Reviews in Endocrine and Metabolic Disorders suggests that transgender women on estrogen therapy are at increased risk for cardiovascular events. The data is unclear for transgender men, but the review highlights the need for further research on hormone therapy's effects in older populations.
A new online tool, Astro-CHARM, has been developed to predict who is at the highest risk of suffering a heart attack or stroke in the next 10 years. The calculator combines coronary artery calcium measurement with traditional risk factors like blood pressure and cholesterol.
A randomized clinical trial of 300 patients in South Korea found that antidepressant escitalopram reduced major adverse cardiac events by 13% compared to placebo. The study followed patients for about eight years, revealing a lower occurrence of cardiac events among those receiving antidepressant treatment.
A study published in the Medical Journal of Australia found that women under-treated for heart attacks die at twice the rate of men. The study adjusted for confounding factors and analyzed data from 41 hospitals across Australia, revealing significant disparities in treatment outcomes between men and women.
A study published in The BMJ found that adding sulfonylurea drugs to metformin for type 2 diabetes is associated with an increased risk of heart attack, all-cause mortality, and severe hypoglycemia. Continuing metformin when introducing sulfonylureas is safer than switching.
The risk of having a heart attack during pregnancy has increased by 25% among American women between 2002 and 2014, according to a new study. The study found that the death rate from heart attacks remains high despite advances in treating these conditions.
New research from the American Heart Association found that regular physical activity can reduce the risk of first and recurrent heart attacks, even in areas with moderate-to-high levels of traffic pollution. Moderate cycling for four or more hours per week cut the risk of recurrent heart attack by 31 percent.
Sekar Kathiresan receives the 2018 Curt Stern Award for his groundbreaking work identifying genetic factors underlying cardiovascular disease risk. His research has led to the development of medicines that mimic protective mutations, reducing heart attack risk.
Testosterone prescriptions decreased in men without a clear indication following reports of increased heart attacks and strokes associated with testosterone use. The steep decline coincided with the FDA safety bulletin, leading to a decrease in prescribed testosterone therapy in the US.
US testosterone prescriptions dropped significantly following reports linking use to cardiovascular events. Between 2013-2016, new users saw a 62% decrease, while established users saw a 48% drop, according to the University of Texas Medical Branch at Galveston study.
A new study found that post-traumatic stress disorder (PTSD) in blue-collar workers who responded to the World Trade Center plane attack on September 11, 2001, may increase their risk of heart attack and stroke. The study, published in Circulation: Cardiovascular Quality and Outcomes Journal, included over 6,800 non-firefighter workers...
Researchers have identified how a new treatment in mice can regenerate the heart after a heart attack by promoting growth of lymphatic vessels and clearing immune cells. This approach showed significant reduction in damaged heart muscle and improved recovery of pumping function.
Researchers at the University of Virginia Health System have discovered a link between sensitivity to an allergen in red meat and increased plaque buildup in heart arteries. This allergy, spread by tick bites, may increase the risk of heart attacks and stroke, highlighting the need for further clinical studies.
Researchers found that patients who couldn't resume work after a heart attack experienced lower quality of life, increased depression, and financial difficulties. The study suggests targeting patients at high risk of not returning to work for targeted interventions.
A new study from MIT and Harvard University introduces the 'Therepi' device, which attaches directly to damaged heart tissue to deliver multiple therapies. The device addresses issues with current drug delivery methods, providing a non-invasive solution for treating heart disease.
Researchers found that a type of immune cell called B cell lymphocytes are responsible for damaging inflammation in the heart after a heart attack. Pirfenidone, an approved lung drug, was shown to effectively reduce this inflammation and protect the heart from further damage.
Research found that major heart attacks were more deadly in the coldest six months of the year compared to the warmer months. The risk of dying within 30 days of a severe heart attack was nearly 50% higher in winter.
A new study from Karolinska Institutet found that patients diagnosed with high-sensitivity troponin test had a lower risk of future heart attacks, with no difference in mortality one year after the heart attack. The test also led to more coronary angiography and balloon angioplasty procedures.
A new blood test using cardiac myosin-binding protein C (cMyC) can rapidly rule out heart attacks in more people than the standard troponin test, freeing up hospital bed space and resources. The test is sensitive enough to give an almost immediate diagnosis, which could save hundreds of thousands of pounds per UK hospital every year.
A new Collaborative Research Center will investigate complex interactions between platelets and inflammatory processes. The project aims to develop novel treatment concepts for diseases associated with platelet dysfunction, such as stroke and acute respiratory failure.
Researchers have discovered that a compound found in green tea can break up potentially dangerous protein plaques in the blood vessels, which can reduce the flow of blood to the heart and brain. This discovery could lead to new medicines to treat heart attack and stroke.
A University of Alberta study found that nearly six per cent of patients have a heart attack without any blockage in the arteries, with five per cent experiencing another heart attack or death within one year. Patients with MINOCA are twice as likely to be female and require more aggressive preventive treatment.
Adults with severe eczema are at a higher risk of cardiovascular problems, including heart attacks and strokes. The study found that patients with severe eczema had a 20-70% increased risk of major cardiovascular events compared to those without eczema.
A new gene therapy approach has shown dramatic reduction of post-infarction arrhythmias in mice by electrically coupling non-excitable cells to undamaged heart cells. The treatment involves introducing a single gene, Connexin43, which bridges the conduction block in damaged hearts.
Researchers found a significant increase in hospitalizations for aortic dissection and ST-Elevation Myocardial Infarctions (STEMI) during winter months. The studies, presented at the SCAI 2018 Scientific Sessions, used the Nationwide Inpatient Sample database to analyze seasonal variations in cardiac-related hospitalizations.
A new study reveals that treating psoriasis with biologic therapy can significantly reduce coronary plaque. The research found that the treatments not only decreased plaque volume but also reduced inflammation, leading to fewer characteristics prone to rupture and cause a heart attack over time.
A recent study published by the European Society of Cardiology found that becoming more physically active after a myocardial infarction halves the risk of dying within four years. The research involved over 22,000 patients and showed that levels of physical activity were reported 6-10 weeks and 12 months after the heart attack.
Researchers found that divorce and low socioeconomic status are associated with a higher risk of recurrent heart events. Patients with higher education levels and household income had lower risks, suggesting marriage may be protective against recurrence.
A new study from the University of Iowa found that statins can save thousands of additional lives when used in people with higher levels of LDL cholesterol. The analysis of 34 previous studies involving over 270,000 participants showed that statins were more likely to reduce death risk at LDL levels of 100 mg/dl or greater.