Articles tagged with Myocardial Infarction
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Researchers at the University of Toronto have discovered bone marrow adult stem cells play a crucial role in repairing damaged hearts. The 'SOS' distress signal mobilizes these cells to stimulate new blood vessel growth and restore heart function.
A Canadian study found that people with diabetes are up to four times more likely to have cardiovascular disease as those without it. Diabetes leads to an earlier high-risk category for CVD, with diabetic men and women being about 15 years younger than non-diabetic counterparts in the same risk group.
A 10-year study found that late career job loss significantly increases the risk of heart attacks and strokes. Individuals over 50 who lost their jobs were nearly twice as likely to experience cardiovascular events compared to those still employed.
The study found that ACTOS reduced the number of patients on insulin and mean daily insulin dose, as well as delaying need for permanent insulin use. In high-risk patients with type 2 diabetes, these results could lead to less dependence on daily insulin use.
Patients who developed heart failure had almost four times the increase in risk of death during follow-up. Implantable defibrillators increased the risk of first hospitalization for heart failure and recurrent hospitalizations by 39% and 58%, respectively.
A new study by Dr. Judith S. Hochman's group demonstrates that some patients who quickly received invasive treatment with angioplasty or open-heart surgery to bypass clogged coronary arteries survive long-term, and the superiority of this treatment is sustained over time.
Researchers at Massachusetts General Hospital developed PET/CT imaging to assess carotid plaque inflammation, identifying patients at high risk for heart attacks. This breakthrough may lead to more targeted interventions and improved patient outcomes.
A study by Yale University School of Medicine found that door-to-balloon time matters for all patients, regardless of time to presentation. The results show a significant decrease in mortality rates when patients receive rapid treatment, even if they arrive late.
The WPI team will use computational modeling, MRI scans, and histological studies to develop a detailed picture of plaque formation and rupture. This research aims to create better diagnostic tools for physicians to assess the risk of arterial plaques and choose effective treatments.
A study published in The Lancet found that patients taking aspirin and dipyridamole had fewer circulatory events compared to those on aspirin alone. This combination therapy reduced the relative risk of vascular death, stroke, or heart attack by 18%.
Researchers are testing innovative techniques to detect vulnerable coronary plaques, which cause most heart attacks. Non-invasive methods like multislice computed tomography show promise in generating colorful pictures of the coronary arteries.
Researchers identified VAMP8 and HNRPUL1 gene variants associated with increased risk of early-onset myocardial infarction. The study analyzed over 2,000 patients and found that carriers of these variants had a comparable risk to conventional risk factors such as smoking and high blood pressure.
A University of Iowa and VA study found that certificate of need programs limit the growth of high-cost medical services but do not harm patients. Hospitals with higher volume rates for certain procedures tend to perform better, suggesting a potential role for regulatory policies in ensuring quality care.
Researchers found that early myocardial enhancement defects on cardiac multidetector CT scans can predict future heart muscle viability in heart attack patients. The study's main conclusion is that these defects are valuable predictors of future myocardial viability.
A meta-analysis of randomized controlled trials found no statistically significant risk reductions from early statin therapy for total death, MI, stroke, cardiovascular death, fatal or nonfatal MI, or revascularization procedures. Serious adverse events associated with early initiation of statins are rare.
A quarter of patients who suffered a heart attack while taking Vioxx did so within the first two weeks of use, new research shows. The study found that cardiovascular risk returns to normal within one month of stopping the drug.
A new study found that patients who saw visual proof of plaque buildup after an EBT scan were more likely to comply with prescribed statin therapy, exceeding 90% compliance. The study also suggests that this method can improve overall health behaviors beyond just medication adherence.
A new compound, bis(phosphocholine)-hexane, has been designed to inhibit the effects of C-reactive protein (CRP), a protein that contributes significantly to heart attack damage. By blocking CRP's tissue-damaging effects, this potential drug may reduce mortality and scar size in patients who have experienced a heart attack.
A study by Eric D. Peterson and colleagues found that hospitals following American College of Cardiology/American Heart Association guidelines had significantly lower in-hospital death rates. Hospitals with higher guideline adherence scores showed a 10% decrease in patient mortality for every 10% increase in composite adherence.
A study of over 39,000 women found that hormone therapy reduced the risk of heart attacks by 32% for those starting treatment in their 50s. However, the risk increased in older women within the first year of treatment before it decreased after two years.
Researchers are conducting a trial to use mesenchymal stem cells (MSCs) to repair damaged heart muscle after a heart attack. The MSCs can be grown in large numbers and stored for years, allowing a single donation to treat thousands of patients.
A new study finds that health care spending generates significant health benefits, with a return on investment of $1.55 to $1.94 for every dollar spent. The research demonstrates the value of estimating the impact of health care investments and challenges policymakers to consider cost-effectiveness in their decision-making.
A team of researchers has identified a potential alternative therapeutic option to COX-2 inhibitors by targeting microsomal prostaglandin E synthase-1 (mPGES-1). Inhibiting mPGES-1 suppresses PGE2 expression while augmenting PGI2 production, without affecting blood clotting or blood pressure.
A new study published in JAMA found that women are at a higher risk of developing angina, a symptom of chest pain or discomfort due to insufficient oxygen supply to the heart muscle. Women with angina and diabetes are particularly at risk of experiencing high rates of death from heart disease
Researchers found that low-dose aspirin prevents platelet clumping in both sexes, with women's platelets reacting more strongly to aspirin before treatment. The study suggests that further research is needed to determine who benefits from aspirin and under what circumstances it works.
Scientists developed research mice with ABCA1 gene mutations to study good cholesterol formation in the liver and intestines. They found that the liver produces 70-80% of HDL, while the intestines produce 20-30%, shedding new light on heart disease prevention.
Researchers found Computed Tomographic Angiography (CTA) quickly and accurately ruled out coronary artery disease in 67% of cases, reducing hospital stay by 45% and saving $300 per patient. Advanced care paramedics also improved STEMI heart attack management, reducing mortality rates from 9% to less than 2%.
A new generation of CT scanner assesses coronary artery health and cardiac anatomy in a single heartbeat, providing clear images of the heart's damage. Researchers also identified predictors of procedural success, including comorbidity and outcome after percutaneous coronary interventions.
The OASIS-6 trial evaluated fondaparinux's safety and effectiveness in patients with ST elevation myocardial infarction (STEMI). Fondaparinux prevents amplification of the coagulation system, potentially reducing death risk from heart attacks.
Researchers analyzed data from 30,324 heart attack patients treated at U.S. hospitals and found that the BNP test was primarily used on high-risk patients with congestive heart failure or older age. However, younger and seemingly healthier patients with elevated BNP levels were at a two to four times greater risk of dying in the hospital.
A pilot project by Duke University Medical Center achieved a significant reduction in 'door-to-reperfusion' time for patients with heart attacks, cutting it down to 50 minutes. The project used wireless ECG transmission from ambulance paramedics to directly link patients with cardiologists.
Researchers found that patients over 64, especially women and minorities, were less likely to be transferred to larger hospitals with revascularization capabilities. This disparity affects mortality rates, with transferred patients having a lower risk of death than those remaining at community hospitals.
Researchers conducted a randomized trial to evaluate the effectiveness of paclitaxel-eluting stents in patients with ST-segment elevation myocardial infarction (STEMI). After one year, the study found that the drug-eluting stent reduced repeat procedures by 67% compared to bare-metal stents.
A new analysis by Duke Clinical Research Institute researchers reveals that Lumbees have a significantly higher burden of cardiovascular risk factors. The study found that Lumbees who came to the hospital for heart treatment had higher rates of diabetes, hypertension, and prior history of coronary artery disease.
A study found that coffee consumption is associated with an increased risk of nonfatal heart attack among individuals with the slow CYP1A2*1F allele, which impairs caffeine metabolism. Those who drank more than 4 cups per day had a significantly higher risk compared to those who consumed less.
A new study suggests that regionalizing heart attack care, similar to trauma care, could be feasible for the US. Nearly 80% of Americans live within a 60-minute ambulance trip of an angioplasty-performing hospital, with most being able to reach one within 30 minutes.
A recent study published in Diabetes reveals that diabetes rates in the US have increased dramatically over the past decade, leading to a sharp rise in hospitalizations and deaths from coronary heart disease. As a result, progress made in reducing illnesses and deaths from this condition may be put at risk.
A Stanford-Kaiser study suggests that statins and beta-blockers can significantly reduce the risk of heart attack in patients with high blood pressure or high cholesterol. The study found that these medications were effective in reducing the risk of heart attack by more than half, even when other treatments for high cholesterol failed.
Researchers found that pre-treatment with vardenafil (Levitra) can open the mitochondrial KATP channel, providing protection against heart attack injury. The findings suggest a new utility for phosphodiesterase-5 inhibitors in cardiac protection beyond erectile dysfunction management.
A study of 17 trials found that pre-intervention drug treatment in ST-elevation heart attacks increased patient mortality and risk of non-fatal heart attacks, strokes, and bleeding. The practice is now recommended against outside of controlled trials.
A Dutch study published in European Heart Journal reveals that 43% of total heart attacks had been clinically unrecognised. Women are more likely to have atypical symptoms and may be less likely for their symptoms to be recognized by doctors.
A large clinical trial found that estrogen therapy did not significantly reduce the risk of coronary heart disease in postmenopausal women. However, there was a suggestion of lower risk in women aged 50-59 years, and fewer cases of revascularization and combined endpoints were reported among those taking estrogen.
Men are more likely to drive themselves to hospital during a heart attack, taking an average of 2.8 hours compared to 14 hours for women. Women often wait longer for treatment and face higher risks from complications.
A study by University of Alberta researchers found that fine particulate matter from pollution causes cardiovascular problems in rats with obesity and insulin resistance. The findings suggest a significant public health risk for vulnerable populations, particularly those living near areas burning coal or diesel exhaust.
Researchers at the University of Houston have developed a new software tool that can detect 'inflamed plaque' in blood vessels, highlighting areas prone to future rupture and blockage. This technology will provide doctors with an early detection method to reduce fatalities due to unpredictable heart attacks.
A new meta-analysis of over 95,000 patients found that aspirin significantly reduces cardiovascular events in both men and women. However, the major reasons for this risk reduction differ between the sexes, with aspirin lowering the risk of heart attacks in men and stroke in women.
A sex-specific meta-analysis of aspirin therapy found that it reduced cardiovascular events by 12% in women and 14% in men. However, it increased the risk of major bleeding events in both sexes. The study suggests that aspirin should be considered for primary prevention in both men and women with preexisting cardiovascular disease.
A study of 76 men found that those taking impotency drugs like Viagra and Cialis were more likely to develop optic nerve damage. Patients with pre-existing heart disease or high blood pressure also showed a higher risk.
Patients receiving emergency angioplasty at highly specialized hospitals have lower risk of death and faster treatment compared to those at less specialized institutions. This study found that hospitals with higher rates of emergency angioplasties perform better, despite the number of procedures not being a key factor in patient survival.
The American College of Cardiology has introduced Clinical Performance Measures to ensure eligible patients receive proven therapies, including aspirin prescription and cholesterol-lowering therapy. By implementing these measures, physicians and hospitals can improve healthcare quality and prepare for the future.
A recent study published in JAMA found that administering L-arginine to patients following a first ST-segment elevation myocardial infarction (STEMI) does not reduce vascular stiffness or improve ejection fraction. In fact, the study suggests that older patients taking L-arginine may be at an increased risk of death after a heart attack.
Researchers found that women have a similar risk of overall mortality and sudden cardiac death following a heart attack as men. ICD therapy reduced mortality risk in both genders, with benefits estimated at 43% for women and 34% for men, according to the re-analysis of the MADIT II study.
Researchers discovered that macrophages secreting a specific enzyme trigger the rupture of unstable plaques in arteries, leading to cardiovascular events. The study suggests targeting this enzyme may help stabilize precarious plaques and reduce the risk of heart attacks and strokes.
Researchers identified a significant increase in stroke risk after heart attack, with risks remaining high for up to three years. The study highlights the importance of monitoring patients and implementing preventative measures such as medication adherence, smoking cessation, and healthy lifestyle habits.
A study of 2,160 people who had heart attacks found a high risk of stroke in the first month after the heart attacks. Hospital care at home was shown to be feasible and cost-effective, with patients receiving similar quality of care as those hospitalized.
A study published in the American Journal of Medicine found that women with similar levels of heart disease as men reported milder symptoms and perceived their disease as severe less often. Researchers suggest this may contribute to differences in heart care delivery between genders.
A study of 4,975 patients found that short-term NSAID use does not increase the risk of heart attack. Long-term NSAID use, particularly for over a year, may slightly raise this risk. The findings also suggest individual NSAIDs have varying cardiovascular effects.
A major study by the European Society of Cardiology links chronic noise exposure to an increased risk of heart attacks, particularly in men and women under 70. The study found that general environmental noise increased risk by nearly 50% for men and three-fold for women, while workplace noise levels affected men's risk but not women's.
A study found that individuals with the shortest delays had a greater probability of experiencing the largest number of symptoms, including sweating, which may prompt them to seek treatment early. Those with longer delays had moderate probability of experiencing chest pain and shortness of breath
A study analyzing follow-up data from the SYNERGY trial found that enoxaparin and unfractionated heparin had similar death or nonfatal MI rates at six months, but mortality at one year was similar. Patients with high-risk ACS features remain at risk for continued adverse cardiac morbidity and mortality.