Articles tagged with Myocardial Infarction
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that consuming vegetables rich in nitrite can reduce heart-muscle damage by 48% and provide protection from heart-attacks. Boosting nitrite levels in the diet could help prevent lasting heart damage or death, particularly for those at increased risk.
A small study found that diesel exhaust increases clot formation and blood platelet activity in healthy volunteers, which could lead to heart attack and stroke. Researchers measured clot formation, coagulation, and inflammatory markers after exposure to diluted diesel exhaust.
Researchers found that adding stents to clot-busting therapy after the optimal treatment window ends doesn't provide significant long-term benefits. The study, which looked at 951 patients, also revealed higher medical costs associated with delayed angioplasty.
A definitive study reveals that placing automated external defibrillators in public spaces can save up to 522 lives annually in the US and Canada. The widespread deployment of battery-powered devices has been shown to more than double survival rates among victims of sudden cardiac death.
A Mayo Clinic study reveals that over half of heart attack patients discontinue taking prescribed medications within three years. Smokers are more likely to stop taking all their medications in the short term, while those in cardiac rehabilitation programs tend to continue medication at a higher rate than non-participants.
Researchers at Mayo Clinic found no link between diabetes treatment and survival rates after a heart attack. The study, which analyzed data from over 2,700 patients, suggests that commonly used medications for managing blood sugar levels do not reduce the likelihood of survival after a heart attack.
The study found that patients who arrived at the hospital within one to two hours of onset had a 77% higher rate of receiving reperfusion therapy, compared to those who waited 11-12 hours. Delayed arrival resulted in lower rates of reperfusion therapy and poorer treatment outcomes.
A study by Johns Hopkins researchers found that only 40% of heart attack patients received recommended aspirin therapy, and 69% of pneumonia patients got recommended antibiotics, highlighting racial, geographic, and financial disparities in access to care.
The HORIZONS AMI trial demonstrated the superiority of bivalirudin over standard drug therapy in reducing net adverse clinical events by 24% and major bleeding by 40% in heart attack patients at 30 days. The study showed significant reductions in cardiac deaths, with a 27% decrease compared to standard therapy.
The AMIHOT II trial found that infusing oxygen-saturated blood into the previously blocked artery after an angioplasty procedure significantly reduced the size of the 'infarct zone', or damaged heart tissue. The study showed a 6.5% reduction in infarct zone size and no significant increase in Major Adverse Cardiac Events at 30 days.
A study of postmenopausal women found that healthy dietary patterns, moderate alcohol consumption, physical activity, a healthy weight, and not smoking were linked to a significantly reduced risk of heart attack. These behaviors, present in 5% of the population, may prevent 77% of myocardial infarctions.
Research suggests that early intervention with angioplasty improves survival and reduces the risk of heart attack in women. Women are at higher risk of bleeding complications, but this does not justify withholding life-saving procedures.
Researchers found a significant drop in blood pressure during the sleep trial, but not during resting or standing trials. This reduction occurred mostly after lights out, just before falling asleep, and may explain the lower cardiovascular mortality associated with siesta-taking.
A study published in JAMA found that chronic job strain after a first heart attack significantly increases the risk of another coronary heart disease event. The study, which included 972 participants, revealed that job strain was associated with a two-fold increase in recurrent CHD events.
A new study from Université Laval found that people who experience chronic job strain after a first heart attack double their risk of suffering from a second one. Researchers discovered that high levels of work stress increase the probability of experiencing another CHD event, even after taking into account other health factors.
Data suggests MIF may provide a target for developing therapeutics to treat West Nile Virus encephalitis. Abnormal microglial cell migration is also implicated in age-related macular degeneration, with CX3CR1-dependent accumulation linked to disease progression.
A study of 3,369 postmenopausal women found that those who experienced at least one full-blown panic attack had a four times higher risk of heart attack and nearly twice the risk of death from any cause. The findings suggest that panic attacks may be an independent risk factor for cardiovascular events.
A Brandeis study found that fewer than one in five patients receive cardiac rehabilitation services after a heart attack or coronary bypass surgery, despite its proven benefits. The use of cardiac rehab varies significantly by age, gender, and geography.
Exposure to particulate matter in mice triggers lung macrophages to produce IL-6, leading to accelerated blood clotting and thrombus formation. Targeting IL-6 may decrease the risk of heart problems caused by air pollution.
New research from Northwestern University's Feinberg School of Medicine identifies how microscopic air pollution kills people at risk. The study found that lungs inflamed by the pollution secrete a substance that causes blood to clot, raising the risk of fatal heart attacks or strokes.
A meta-analysis of pioglitazone treatment found a significant reduction in heart attack, stroke, and death rates among type 2 diabetes patients, with no significant increase in cardiovascular death. However, the treatment also increased the risk for serious heart failure.
A new analysis of four studies found that long-term use of Avandia increased the risk of heart attack by 42% and doubled the risk of heart failure. The study, published in JAMA, suggests that the drug may cause over 4,000 excess heart attacks and 9,000 excess cases of heart failure per year.
Researchers at Ohio State University have identified a molecule that can reverse damage and help restore blood flow to vessels constricted during a heart attack. The treatment involves delivering tetrahydrobiopterin directly to the vessels, which can improve outcomes for patients with acute coronary episodes.
Patients with depression have impaired heart rate variability recovery after acute coronary syndromes, but treatment with antidepressants improves this ability. Sertraline treatment also increased heart rate variability in depressed patients.
Patients with diabetes and acute coronary syndromes have a significantly higher risk of death at 30 days and one year compared to those without diabetes. The study found that diabetes increased the risk of death by nearly 80% at 30 days for patients with unstable angina/non-STEMI and 40% for those with STEMI.
A re-analysis of the data used in a controversial meta-analysis suggests that rosiglitazone's cardiovascular risks may not be as high as initially reported. The study finds that only prospective clinical trials can definitively establish the drug's safety.
Researchers identified a new player in the control of good cholesterol that circulates in the bloodstream and reduces heart attack risk. By manipulating levels of an enzyme called proprotein convertases, they were able to boost or reduce HDL-C levels, offering potential for therapies against heart disease.
The revised guidelines introduce changes to the initial diagnostic approach, recommending a non-invasive set of preliminary tests such as stress tests or echocardiograms. The new guidelines also emphasize the importance of more intense lipid and blood pressure control, as well as the use of anti-platelet therapy clopidogrel for at leas...
A study published in The American Journal of Medicine found that emergency angioplasty use has increased, but 10% of eligible patients are still going untreated for life-saving treatment after a heart attack. Patients without typical symptoms or from underrepresented groups are most likely to miss out on this critical care.
A new study found that emergency angioplasty treatment for heart attacks has increased dramatically over the last decade, with a notable decline in patients going without crucial care. However, 10% of eligible patients still do not receive this urgent treatment, highlighting gaps in care for certain subgroups.
Researchers demonstrate in rats that a periostin patch can stimulate heart cell regeneration and improve cardiac pumping ability. The treated rats showed improved ventricular remodeling, decreased scarring, and increased cardiomyocyte proliferation.
Two studies found that elevated nonfasting triglyceride levels are associated with an increased risk of heart attacks, ischemic heart disease, and death. The findings suggest that remnant lipoproteins play a dominant role in postprandial atherosclerosis, and may predict the risk of cardiovascular events in women.
A recent study published in the European Journal of Cardiovascular Nursing reveals that women who have suffered heart attacks experience higher rates of lingering depressive symptoms compared to their male counterparts. Women scored lower in physical and social functioning after one year, with 14.3% experiencing worsening depression.
A study suggests that taxing high-fat foods in the UK could prevent up to 3,000 heart attack and stroke deaths annually. This approach would increase salt intake instead of reducing it, leading to potential health issues.
A recent study by the University of Edinburgh found that South Asian Scots are more likely to suffer a heart attack than the rest of the Scottish population. The research, which linked census data to hospital discharge records, revealed an 80% higher incidence of heart attacks among South Asian women and a 45% higher incidence among men.
A new study found high levels of MPO to signal increased risk for heart disease nearly a decade before conventional risk factors set off alarms. Elevated MPO levels also indicate unstable plaque and may be used to detect vulnerable patients.
Researchers explored the use of autologous cells derived from bone marrow cells (BMC) to strengthen cardiac function and prevent heart attacks. The study found a significant reduction in clinical events, including death, heart attack, or revascularization, in patients who received BMC infusion compared to placebo.
Researchers will inject selected stem cells from patients' own bone marrow into their hearts during coronary bypass surgery. The goal is to prevent late scar formation and improve heart contraction, reducing the risk of congestive heart failure.
Research published in the European Heart Journal reveals obese and very obese patients have a lower risk of dying after treated for heart attacks compared to normal-weight patients. After three years of follow-up, obese patients had less than half the long-term mortality rate as normal BMI patients.
A multidisciplinary team approach has successfully treated acute heart attacks by expediting patients to specialized treatment centers within 90 minutes. This program evaluation demonstrates improved outcomes for ST-segment elevation myocardial infarction patients in Canada.
A study found that paying hospitals extra money for following treatment guidelines didn't improve patient outcomes. However, providing hospitals with the necessary information to improve care did lead to better results.
A study found that only 32% of adults possess minimal medical knowledge of serious health conditions, despite higher education or personal experience not providing significant improvement. This lack of awareness poses a risk to early detection and treatment outcomes, as well as public health costs and behavior.
Women who drink in moderation have a significantly lower risk of heart attack compared to abstainers, with daily drinkers experiencing the most benefits. Moderate drinking reduces heart attack risk regardless of beverage preference or pattern.
A new study has found that sleep apnea significantly increases the risk of heart attack or death over a period of four to five years. Researchers followed 1,123 patients with sleep apnea for five years and found that those with more severe symptoms were at higher risk of developing heart disease.
A study found that diabetic patients who continued long-term clopidogrel therapy had lower rates of heart attack and death compared to those who discontinued the medication, regardless of stent type. Long-term clopidogrel therapy was particularly beneficial in reducing mortality risk with bare metal stents.
A study by Society for Cardiovascular Angiography and Interventions (SCAI) uses wireless technology to transmit ECGs from paramedics' smartphones to cardiologists, allowing for faster treatment of heart attacks. The system has cut the door-to-balloon time in half, improving patient care.
A study of over 8,000 British government workers found that unfair treatment increased the risk of a heart attack or angina, with those in the highest category being 55% more likely to have serious heart disease. Women and lower-income individuals were also disproportionately affected.
Pretreatment with high-dose clopidogrel (600 mg or more) reduces the risk of cardiac death or nonfatal heart attack by 50% during hospitalization and within 30 days after PCI. The study found no increase in major or minor bleeding, regardless of dose.
Experts disagree on the criticality of a 90-minute door-to-balloon time in heart attack treatment. Dr. Eric R. Bates believes that timely balloon inflation is crucial for better outcomes, while Dr. Timothy D. Henry argues that an arbitrary deadline may be counterproductive in some cases.
Young women with heart disease often experience atypical symptoms such as jaw pain, sweating, and shortness of breath. These individuals are twice as likely to die in the hospital compared to similarly aged men, highlighting the need for prompt medical attention and increased awareness of risk factors.
Two studies reveal that off-label and untested use of drug-coated stents is common in US practice, associated with higher ischemic complication rates and worse short-term outcomes. The studies found that approximately half of all use of drug-eluting stents occurs in off-label or untested settings.
A University of Kentucky study finds that doses higher than a baby aspirin may not prevent cardiovascular events and increase bleeding risk. The research suggests that using the minimum effective dose of 75-81 mg may be optimal for most patients.
A randomized trial found that angioplasty significantly reduced long-term cardiac events compared to intensive drug therapy among heart attack survivors with silent ischemia. The study followed 201 patients for an average of 10.2 years, revealing a persistent benefit of PCI.
A common genetic variation on chromosome 9p21 is linked to a substantial increase in risk for heart attack, with individuals carrying the variation having a 1.64-fold greater risk of suffering a heart attack. The study found that approximately 21 percent of individuals of European descent carry two copies of the genetic variation.
Researchers found a significant decline in death rates and heart failure among patients with severe heart attacks, with reductions of 4.5% and 11%, respectively. The study also showed improvements in stroke and further heart attack risk.
A new international study found that patients who received modern treatments after a heart attack or severe chest pain had significantly lower death rates, stroke risks, and heart failure. The study shows improved outcomes due to increased use of guideline-based treatments such as drugs, tests, and procedures.
Recent changes in treatment guidelines for acute coronary syndromes have been associated with reductions in heart failure, stroke, and death rates. The use of pharmacological medications increased over time, while primary PCI rates rose by 37 percentage points.
Researchers found HIV-infected patients had a higher incidence of heart attacks and major cardiovascular risk factors compared to noninfected patients. The study's findings indicate that HIV-infected individuals should be assessed for cardiovascular risks and that strategies to modify those risks are urgently needed.
A study published in JAMA found that ranolazine is safe but ineffective in reducing major cardiovascular events, such as death or heart attack, in patients with acute coronary syndromes. The medication showed a reduced risk of recurrent ischemia, but failed to improve overall cardiovascular outcomes.
The FDA has added 'black box' warnings to all prescription and over-the-counter pain relievers, despite evidence showing naproxen is safe. This decision ignores the risk differences between nonsteroidal anti-inflammatory drugs, with Voltaren carrying the highest risk of heart attack.