Articles tagged with Myocardial Infarction
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A survey found that nearly half of people with diabetes are not using aspirin as prescribed, despite its proven benefits in reducing heart attack and stroke risk. The study highlights the need for better communication between healthcare professionals and patients, particularly those with diabetes who are at higher risk.
A study of 5,700 patients found that carriers of a specific genetic variation had a 43% higher risk of death, heart attack, or stroke. The research aims to tailor drugs to individual patients based on their genetic makeup, potentially leading to safer and more effective treatments.
Darbepoietin showed significant protection to heart tissue and improved cardiac function when administered 1-2 hours or 24 hours after an ischemic event. The findings suggest potential for quick translation into clinical trials.
The PROactive study shows ACTOS significantly reduced the recurrence of heart attacks and acute coronary syndrome in high-risk patients with type 2 diabetes. The medication demonstrated a 28 percent reduction in fatal or non-fatal heart attacks, as well as a 37 percent risk reduction in acute coronary syndrome.
A two-year study involving over 2,500 heart failure patients found that hospitals that cooperated to deliver proven care and educate patients saw lower death rates and rehospitalization rates. The project used a toolkit of standard admission orders, clinical pathways, and discharge checklists to ensure optimal care.
Researchers have discovered that stem cells derived from human heart tissue can develop into cardiospheres that express normal properties of primitive heart tissue. These cardiospheres were then grown in the laboratory and injected into mice with lab-induced heart attacks, where they migrated to damaged tissue and regenerated, improvin...
A study of 14,200 patients with type 2 diabetes found that fenofibrate reduced total CVD events by 11% due to a decrease in non-fatal heart attacks and bypass surgery. The drug was well-tolerated but associated with increased risks of pancreatitis and pulmonary embolism.
High doses of COX-2 inhibitors and other NSAIDs are associated with a higher risk of death, according to the study. Patients taking high doses of celecoxib or rofecoxib were found to be at a strikingly higher risk of death compared to those not taking NSAIDs.
Researchers found significant disparities in health status outcomes between African-Americans and whites, with blacks experiencing more angina, physical limitations, and poorer quality of life one year after an acute coronary syndrome. These disparities remained even after adjusting for hospital treatments and other factors.
A recent study found that obesity measured by waist-to-hip ratio is three times stronger than BMI in predicting the risk of heart attack. The researchers analyzed data from over 27,000 people across 52 countries and discovered a striking correlation between waist size and cardiovascular risk.
A recent study found that waist-to-hip ratio is a stronger predictor of heart attack than BMI in diverse ethnic populations. The researchers discovered that larger waist size was harmful, while larger hip size was protective, leading to substantial reassessment of obesity's importance for cardiovascular disease worldwide.
A new drug, clopidogrel, has been shown to significantly reduce deaths from heart attacks, with a 9% decrease in mortality rates compared to placebo. The treatment also resulted in a 14% reduction in repeat heart attacks during the study period, highlighting its potential to save thousands of lives each year.
A study of 11,481 childhood cancer survivors found that 20% had physical performance limitations compared to 12% of their siblings. Rehabilitation programs improved survival rates after heart attacks by reducing subsequent heart attacks by 17%.
Researchers have made a breakthrough in cardiac regeneration using bone marrow stem cells, improving left ventricular function and reducing infarct size in patients with old myocardial infarction. The therapy is safe, simple, and shows promising results, paving the way for larger trials to confirm its effectiveness.
Patients taking ASA plus dipyridamole had increased rates of myocardial infarction, but the addition of dipyridamole is rarely justified for stroke prevention. ASA remains the gold standard treatment for preventing stroke in high-risk patients.
A study found that drug-eluting stents significantly reduce the risk of restenosis in vein grafts, cutting heart attack rates by fourfold compared to bare metal stents. The treatment also decreases repeat procedures and death rates, suggesting a long-term advantage for patients with worn and diseased vein grafts.
In a randomized study, animals received injections of their own adipose stem and regenerative cells after a simulated heart attack. This approach resulted in a statistically significant reduction in perfusion defects and improved ejection fraction.
A large multicenter randomized study involving 384 patients found the CYPHER Stent to have a superior safety profile compared to intravascular brachytherapy. The study showed lower incidence of target vessel failure and major adverse cardiac events with the CYPHER Stent at nine-month follow-up.
Physicians at Providence Hospital have developed an early triage system using cell phones and ECGs to quickly transmit tracing data from paramedics in the field to emergency rooms, reducing average door-to-balloon time from 88 to 44 minutes.
A study published in Alcoholism: Clinical & Experimental Research found that moderate drinking is associated with lower levels of stickiness in platelets, which can lead to fewer blood clots. The research, conducted on over 1,000 participants, suggests that moderate alcohol consumption may have a protective effect against cardiovascula...
A study published in The Lancet found that pioglitazone reduces the risk of cardiovascular events in patients with type 2 diabetes. The treatment group experienced fewer adverse events and a lower risk of death from heart failure compared to the placebo group.
An international study found that 21% of coronary patients continued to smoke, with younger patients and those with angina less likely to quit. The survey highlights the need for more effective smoking cessation programs, particularly among younger patients and those with lower education levels.
Researchers at Yale University found innovative approaches to ensuring rapid treatment of patients, including management techniques and flow charts. The study identified key success factors for improving quality care in hospitals, with a focus on proper organization, planning, and communication.
A new study published in the Journal of the American College of Cardiology found that hospitals using quality-improvement tactics reduced heart attack death rates by 21-26%. The effort involved a checklist to ensure patients received crucial treatments and lifestyle advice, leading to improved patient outcomes.
A study of top-performing hospitals reveals the importance of timely angioplasty treatment in heart attacks. Successful hospitals employ a range of strategies to meet the 90-minute door-to-balloon time standard, including pre-hospital ECGs and collaborative teamwork.
According to a recent review, approximately 15% of heart attack patients develop post-traumatic stress disorder (PTSD), which can lead to impairments in social functioning, vitality, and physical health. The study also identifies risk factors for PTSD in cardiovascular disease patients.
A large analysis of Medicare records suggests that aspirin is not harmful and may even lower mortality rates in patients with heart failure and coronary artery disease. However, the debate remains controversial, with some experts recommending limiting or avoiding aspirin use for these patients.
Cardiac stress testing reveals a significant association between exercise capacity and heart rate recovery with CHD mortality rates. The study found that asymptomatic individuals with below-average test scores were two to four times more likely to die from CHD within 10-20 years.
The PROactive study shows that ACTOS significantly improves cardiovascular outcomes by reducing heart attacks, strokes, and death in high-risk patients. The study found a 16% reduction in life-threatening events and significant improvements in lipid profiles, blood pressure, and insulin resistance.
A review by Devereaux and colleagues highlights the risks of non-cardiac surgery, with 500,000 to 900,000 patients experiencing cardiac events each year. The authors discuss methods for estimating risk pre-operatively and communicating these findings to clinicians.
A new study reveals that women who suffer from heart attacks are more likely to experience longer hospital delays compared to their male counterparts. The study, which analyzed data from six major hospitals in Dublin, found that women were medically assessed an average of 30 minutes after arrival, while men received medical attention i...
A study of 3779 patients found women were 20% less likely to undergo an exercise test or angiography due to suspected coronary obstruction. Despite proven coronary disease, women received less aggressive treatment and were twice as likely to die or suffer a heart attack compared to men.
Researchers from Norway found that treating patients with high doses of B vitamins after a heart attack does not prevent recurrent heart disease or stroke. In fact, high doses of B vitamins may increase the risk of cardiovascular disease, particularly among those with impaired renal function.
The article highlights the significant disparity in cardiovascular disease (CVD) knowledge and treatment among European women. Women are more likely to develop CVD ten years after men, but it is also more lethal when it occurs suddenly, such as one year after a heart attack.
A new study has shown that fondaparinux, a synthetic drug, is as effective as traditional therapy in preventing heart attacks and ischemia while reducing major bleeding risks. Patients with acute coronary syndromes who received fondaparinux had lower mortality rates at one month and six months compared to those receiving enoxaparin.
The OASIS-5/MICHELANGELO study found fondaparinux to be as effective as enoxaparin in preventing heart attacks and death at nine days after an event, but demonstrated a dramatic reduction in major bleeding. Patients also had a lower mortality rate at six months.
A new study published in the JAMA Network found that clopidogrel pretreatment significantly reduced the odds of cardiovascular death, heart attack, or stroke following PCI by 46% compared to treatment at the time of PCI. Pretreatment also resulted in a 41% reduction in cardiovascular death from randomization through 30 days.
Research by Dr Andrew Lawrence and Cameron McPherson found adolescent rats exposed to amphetamine had a more sensitised reaction when re-administered as adults, increasing the risk of heart attack. The study suggests teenage experimentation with drugs may have long-term effects on brain function.
A new study published in the American Journal of Cardiology found that early statin therapy can significantly reduce mortality and other complications in heart attack victims. Patients who received statins before or within 24 hours of hospitalization had a 54% lower risk of in-hospital mortality, compared to those not on statin therapy.
New study finds that women and black patients with a heart attack are less likely to receive recommended treatments, including aspirin and reperfusion therapy. The researchers also found that cardiac catheterization was used less frequently in these patient groups.
Researchers at the Mayo Clinic have discovered that measuring C-reactive protein levels can help identify patients with stiffened arteries, which increases the risk of heart attack and stroke. The study suggests that suppressing low-grade inflammation may be a potential target for improving arterial health.
A new epidemiological study from the University of Pennsylvania School of Medicine found a protective relationship between non-aspirin, non-steroidal drugs (NANSAIDs) and heart attacks. The study used patient surveys instead of administrative databases, which may have skewed previous results.
A new study finds that ethnic minorities in Scotland experience a 60-70% higher incidence of heart attacks compared to non-South Asians. Poorer socio-economic status, environmental factors, barriers to healthcare, and genetic factors contribute to these disparities.
A study found persistent racial and gender disparities in heart attack care, with black women having lower rates of reperfusion therapy and higher in-hospital mortality rates compared to white men. The differences were not explained by patient characteristics, raising concerns about under-treatment.
A study by Yale University researchers found that delayed treatment for heart attacks treated outside regular hours leads to increased mortality rates. PCI therapy, which opens narrowed coronary arteries, is more effective when administered promptly, but delays result in reduced survival benefits.
A study of 372 community-dwelling older patients found that those receiving high-quality care had better survival rates than those without it. The research created a quality-of-care score based on 236 process-of-care measures, with survival improving steadily as the score increased.
Researchers followed 8527 people over 13 years to investigate the link between depression, fatigue, and cancer. Despite finding behaviors that increased cancer risk, they found no association between vital exhaustion scores and cancer risk.
A new review of the American College of Cardiology and American Heart Association guidelines aims to streamline diagnosis and treatment of acute coronary events. The goal is to provide faster treatment that may even prevent a heart attack or damage to the heart before it happens, benefiting millions of patients each year.
Researchers at Johns Hopkins Medicine have successfully treated heart attacks in animals using adult mesenchymal stem cells. The goal is to develop a widely applicable treatment to repair and reverse heart muscle damage caused by infarction.
A study of depressed heart patients found that those with low heart rate variability were nearly three times more likely to die after a heart attack. Researchers hope that treating depression and correcting heart rate variability may offer improved survival rates for these patients.
A VCU study found that low-dose oral contraceptives double the risk of cardiovascular events, such as heart attacks and strokes, among women. Women with PCOS or metabolic disorders are particularly at increased risk.
A new study called MESA Air aims to better define air pollution standards by tracking the development of atherosclerosis and cardiovascular events in 8,700 participants. The researchers will measure the effect of repeated exposure to six major air pollutants over a 10-year period.
A large study of 39,876 healthy women found no effect of vitamin E on total cancer or cardiovascular disease. However, vitamin E supplementation was associated with a reduced risk of cardiovascular deaths among all women and a decrease in heart attacks and cardiovascular deaths among women aged 65 years and older.
A study found that antidepressants reduced the risk of death and non-fatal heart attacks by 43% in depressed heart attack patients. The analysis was based on data from the Enhancing Recovery in Coronary Heart Disease clinical trial, which randomized 2,481 patients with depression or social isolation between 1996 and 1999.
A new study suggests that antidepressants can help reduce the risk of heart attacks and death among patients who have had a heart attack and are experiencing depression. The ENRICHD study found that patients taking antidepressants had a 43% lower risk of death or recurrent non-fatal heart attack, compared to those not taking them.
Researchers at UC Davis have discovered a receptor pathway for C-reactive protein, a known risk marker for heart disease. Blocking this pathway with specific antibodies reverses the detrimental effects of CRP on endothelial cells.
A study published in the Canadian Medical Association Journal found that levels of ischemia-modified albumin provided no useful information in predicting which patients with potential acute coronary syndrome would experience serious cardiac outcomes. The analysis suggests that prognosis may precede diagnosis in these cases.
A double-blind trial found that fish oil supplements did not reduce the risk of sudden death or heart attack in patients with implantable cardioverter defibrillators. Instead, patients taking fish oil were more likely to experience recurrent ventricular fibrillation events.
A recent study suggests that chest CT scans can be used to identify patients who have had a heart attack. The study found that normal heart muscle enhancement is reduced in patients who have had a recent heart attack, making it possible for radiologists to look for this sign as the first step in identifying a potential heart attack. Fu...
Researchers found tamoxifen does not lower heart attack risk in breast cancer survivors and increases risk with radiation therapy. Tamoxifen use was linked to a doubled heart attack risk among women who also received radiation therapy, regardless of the duration or dose of the drug.