Articles tagged with Myocardial Infarction
The PROactive study shows that ACTOS significantly improves cardiovascular outcomes by reducing heart attacks, strokes, and death in high-risk patients. The study found a 16% reduction in life-threatening events and significant improvements in lipid profiles, blood pressure, and insulin resistance.
A review by Devereaux and colleagues highlights the risks of non-cardiac surgery, with 500,000 to 900,000 patients experiencing cardiac events each year. The authors discuss methods for estimating risk pre-operatively and communicating these findings to clinicians.
The OASIS-5/MICHELANGELO study found fondaparinux to be as effective as enoxaparin in preventing heart attacks and death at nine days after an event, but demonstrated a dramatic reduction in major bleeding. Patients also had a lower mortality rate at six months.
A study of 3779 patients found women were 20% less likely to undergo an exercise test or angiography due to suspected coronary obstruction. Despite proven coronary disease, women received less aggressive treatment and were twice as likely to die or suffer a heart attack compared to men.
Researchers from Norway found that treating patients with high doses of B vitamins after a heart attack does not prevent recurrent heart disease or stroke. In fact, high doses of B vitamins may increase the risk of cardiovascular disease, particularly among those with impaired renal function.
The article highlights the significant disparity in cardiovascular disease (CVD) knowledge and treatment among European women. Women are more likely to develop CVD ten years after men, but it is also more lethal when it occurs suddenly, such as one year after a heart attack.
A new study has shown that fondaparinux, a synthetic drug, is as effective as traditional therapy in preventing heart attacks and ischemia while reducing major bleeding risks. Patients with acute coronary syndromes who received fondaparinux had lower mortality rates at one month and six months compared to those receiving enoxaparin.
A new study published in the JAMA Network found that clopidogrel pretreatment significantly reduced the odds of cardiovascular death, heart attack, or stroke following PCI by 46% compared to treatment at the time of PCI. Pretreatment also resulted in a 41% reduction in cardiovascular death from randomization through 30 days.
Research by Dr Andrew Lawrence and Cameron McPherson found adolescent rats exposed to amphetamine had a more sensitised reaction when re-administered as adults, increasing the risk of heart attack. The study suggests teenage experimentation with drugs may have long-term effects on brain function.
A new study published in the American Journal of Cardiology found that early statin therapy can significantly reduce mortality and other complications in heart attack victims. Patients who received statins before or within 24 hours of hospitalization had a 54% lower risk of in-hospital mortality, compared to those not on statin therapy.
New study finds that women and black patients with a heart attack are less likely to receive recommended treatments, including aspirin and reperfusion therapy. The researchers also found that cardiac catheterization was used less frequently in these patient groups.
Researchers at the Mayo Clinic have discovered that measuring C-reactive protein levels can help identify patients with stiffened arteries, which increases the risk of heart attack and stroke. The study suggests that suppressing low-grade inflammation may be a potential target for improving arterial health.
A new epidemiological study from the University of Pennsylvania School of Medicine found a protective relationship between non-aspirin, non-steroidal drugs (NANSAIDs) and heart attacks. The study used patient surveys instead of administrative databases, which may have skewed previous results.
A study found persistent racial and gender disparities in heart attack care, with black women having lower rates of reperfusion therapy and higher in-hospital mortality rates compared to white men. The differences were not explained by patient characteristics, raising concerns about under-treatment.
A new study finds that ethnic minorities in Scotland experience a 60-70% higher incidence of heart attacks compared to non-South Asians. Poorer socio-economic status, environmental factors, barriers to healthcare, and genetic factors contribute to these disparities.
A study by Yale University researchers found that delayed treatment for heart attacks treated outside regular hours leads to increased mortality rates. PCI therapy, which opens narrowed coronary arteries, is more effective when administered promptly, but delays result in reduced survival benefits.
A study of 372 community-dwelling older patients found that those receiving high-quality care had better survival rates than those without it. The research created a quality-of-care score based on 236 process-of-care measures, with survival improving steadily as the score increased.
Researchers followed 8527 people over 13 years to investigate the link between depression, fatigue, and cancer. Despite finding behaviors that increased cancer risk, they found no association between vital exhaustion scores and cancer risk.
A new review of the American College of Cardiology and American Heart Association guidelines aims to streamline diagnosis and treatment of acute coronary events. The goal is to provide faster treatment that may even prevent a heart attack or damage to the heart before it happens, benefiting millions of patients each year.
Researchers at Johns Hopkins Medicine have successfully treated heart attacks in animals using adult mesenchymal stem cells. The goal is to develop a widely applicable treatment to repair and reverse heart muscle damage caused by infarction.
A study of depressed heart patients found that those with low heart rate variability were nearly three times more likely to die after a heart attack. Researchers hope that treating depression and correcting heart rate variability may offer improved survival rates for these patients.
A VCU study found that low-dose oral contraceptives double the risk of cardiovascular events, such as heart attacks and strokes, among women. Women with PCOS or metabolic disorders are particularly at increased risk.
A new study called MESA Air aims to better define air pollution standards by tracking the development of atherosclerosis and cardiovascular events in 8,700 participants. The researchers will measure the effect of repeated exposure to six major air pollutants over a 10-year period.
A large study of 39,876 healthy women found no effect of vitamin E on total cancer or cardiovascular disease. However, vitamin E supplementation was associated with a reduced risk of cardiovascular deaths among all women and a decrease in heart attacks and cardiovascular deaths among women aged 65 years and older.
A new study suggests that antidepressants can help reduce the risk of heart attacks and death among patients who have had a heart attack and are experiencing depression. The ENRICHD study found that patients taking antidepressants had a 43% lower risk of death or recurrent non-fatal heart attack, compared to those not taking them.
A study found that antidepressants reduced the risk of death and non-fatal heart attacks by 43% in depressed heart attack patients. The analysis was based on data from the Enhancing Recovery in Coronary Heart Disease clinical trial, which randomized 2,481 patients with depression or social isolation between 1996 and 1999.
Researchers at UC Davis have discovered a receptor pathway for C-reactive protein, a known risk marker for heart disease. Blocking this pathway with specific antibodies reverses the detrimental effects of CRP on endothelial cells.
A study published in the Canadian Medical Association Journal found that levels of ischemia-modified albumin provided no useful information in predicting which patients with potential acute coronary syndrome would experience serious cardiac outcomes. The analysis suggests that prognosis may precede diagnosis in these cases.
A double-blind trial found that fish oil supplements did not reduce the risk of sudden death or heart attack in patients with implantable cardioverter defibrillators. Instead, patients taking fish oil were more likely to experience recurrent ventricular fibrillation events.
A recent study suggests that chest CT scans can be used to identify patients who have had a heart attack. The study found that normal heart muscle enhancement is reduced in patients who have had a recent heart attack, making it possible for radiologists to look for this sign as the first step in identifying a potential heart attack. Fu...
Researchers found tamoxifen does not lower heart attack risk in breast cancer survivors and increases risk with radiation therapy. Tamoxifen use was linked to a doubled heart attack risk among women who also received radiation therapy, regardless of the duration or dose of the drug.
The study found that levels of biomarkers linked to arterial inflammation and heart attack risk decreased after taking the drug DG-031. The drug reduced production of leukotriene B4 by 26 percent and myeloperoxidase by 12 percent, suggesting a potential reduction in cardiovascular events.
Researchers found that morphine increased mortality rates by 6.8% compared to nitroglycerin, even after adjusting for clinical risk. The study calls for a randomized clinical trial to confirm the findings and advises cardiologists to prioritize nitroglycerin treatment.
A new study found that computerized risk stratification tools, like ACI-TIPI, may not accurately diagnose heart attacks in patients from different ethnicities. The researchers compared the tool's performance in a mixed-race US population and an Asian population in Singapore.
A recent US study found no benefit from treating C. pneumoniae bacteria with an antibiotic in reducing the risk of heart attack or improving overall cardiac outcomes. The Azithromycin coronary events study (ACES) assigned over 4,000 participants to receive either antibiotics or a placebo for one year.
A new study found that antibiotic treatment with azithromycin did not reduce the risk of heart attacks, unstable angina, or other cardiac events. The study enrolled over 4,000 participants and followed them for nearly four years, with no significant difference in outcomes between those receiving antibiotics and placebo.
Researchers at Monash University have developed a new class of drugs that stop the formation of blood clots without increasing bleeding risk, offering a safer alternative to aspirin. The PI 3-kinase inhibitors may prove vital in treating heart attack and stroke patients, with promising results from animal studies and phase I trials.
A new study found that low concentrations of sodium nitrite prevent cell death in the hearts and livers of mice undergoing experimental heart attack and liver injury. The potent protective effect reduced dead tissue by 67% compared to control animals given nitrate.
A recent study has found that patients who received incorrect doses of fibrinolytic agents were more likely to have underlying health conditions, such as lower systolic blood pressure and body weight. These findings suggest that adverse outcomes from blood clot therapy may be due to patient characteristics rather than dosing errors.
A study analyzing ASSENT-2 clinical trial data found no significant association between small dosing errors and increased mortality rates among heart attack patients. However, patients with certain factors such as advanced age, female gender, and lower blood pressure were more likely to experience adverse events.
Researchers found a strong association between high levels of C. pneumoniae antibodies and the occurrence of heart attacks in young men. The study suggests that C. pneumoniae may play a role in the pathogenesis of heart disease, but further research is needed to confirm the link.
The study found that women who received stents experienced a significant reduction in major adverse cardiac events and death rates compared to those treated with balloon angioplasty. Stenting was also shown to decrease the need for re-intervention, a critical factor contributing to higher mortality risk in women.
A new study from Rice University found no independent relationship between Lp(a) levels and coronary calcium in either whites or African-Americans, suggesting an unknown mechanism may be at work. The study used a large multiethnic dataset of Dallas County residents to examine the link between Lp(a) and heart-attack risk.
Researchers at Cincinnati Children's Hospital Medical Center discovered that blocking cyclophilin D protects the heart from injury due to loss of blood flow. A class of drugs already exists that blocks cyclophilin D and has been shown to protect against stroke in animal models.
A study used optical coherence tomography (OCT) to visualize coronary arteries and identify vulnerable plaques in cardiac patients. The technology revealed that heart attack and acute coronary syndrome patients had more lipid and thinner fibrous caps than stable angina patients.
The Hopkins team is conducting a Phase I study to test the safety of injecting donor adult stem cells into patients who have recently suffered a heart attack. The study aims to determine if the stem cells can repair damage to the heart muscle and restore its function.
A review of studies published in Psychosomatic Medicine found that physically fit people have a reduced risk of heart attacks, while inactive cardiac patients who engage in vigorous activity are at higher risk. Strong emotions and stress can also trigger heart attacks in vulnerable individuals.
The new guidelines emphasize the importance of timely thrombolysis and PCI, with a focus on reducing delays in treatment. They also highlight the benefits of primary PCI over thrombolysis in certain situations.
Yale researchers question the feasibility of regionalized heart attack care in the US, citing differences in healthcare systems and clinical accuracy. They estimate that transferring over 500,000 patients could be necessary for access to interventional treatments.
A study published in Heart found that antidepressants may explain the increased risk of heart attack associated with their use. Patients who recently started antidepressants were twice as likely to have a heart attack within seven days compared to those who hadn't taken the medication before.
A new study published in Heart found that individuals with giant cell arteritis (GCA) have a significantly higher risk of cardiovascular disease compared to healthy adults. The prevalence of GCA is estimated at one per every 500 seniors, and patients with this condition are more than twice as likely to experience heart attacks or strokes.
A new study found that emergency use of clopidogrel could reduce the risk of death and repeat heart attacks by up to 10%, without increasing serious bleeds. However, early treatment with metoprolol may increase the risk of cardiac shock, and its benefits tend to cancel out those of clopidogrel.
The Women's Health Study found that low-dose aspirin lowered the incidence of a first major cardiovascular event by 9 percent, with a statistically significant difference in stroke prevention. For women aged 65 and older, the risk was reduced by 26 percent, but the benefits must be weighed against the risk of internal bleeding.
Researchers found a significant association between depression and ventricular tachycardia, a precursor to sudden cardiac death, in hospitalized heart attack patients. The risk of ventricular tachycardia increased with increased levels of depression.
A recent study published in JAMA found that distal microcirculatory protection devices used during angioplasty procedures in heart attacks failed to improve patient outcomes. Despite successfully removing debris from arteries, the treatment did not reduce major adverse cardiac events or affect ST segment normalization.
Researchers confirm Vioxx increased cardiovascular risk by nearly doubling events, including heart attacks and strokes, in patients with recurrent colon polyps. The trial was stopped early due to safety concerns.
Researchers at Johns Hopkins Medicine have discovered 'broken heart' syndrome, a condition where emotional stress triggers severe but reversible heart muscle weakness. The study found that patients experienced rapid improvement in heart function within days and complete recovery within two weeks.
Researchers found that rheumatoid arthritis patients are three times more likely to have been hospitalized for an acute heart attack during the two years before diagnosis. They were also twice as likely to experience unrecognized heart attacks and sudden cardiac deaths after diagnosis.
Researchers have discovered a single human stem cell population derived from the bone marrow that can regenerate myocardium after myocardial infarction. This breakthrough has significant implications for treating heart failure and major morbidity associated with myocardial infarction.
A study by McGill University researchers found that COX-2 inhibitors like Vioxx increase the risk of heart attack by 24% in users who have not previously suffered a heart attack. Aspirin use can help mitigate this risk, but only in those taking low doses of Vioxx.