Articles tagged with Obesity
A new study finds that obesity is biologically associated with an unsatisfying sex life, which can be reversed through weight loss via gastric bypass surgery. Researchers measured reproductive hormone levels and quality of life ratings in obese men before and after surgery.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that obese women have detrimental changes in their ovaries, leading to poorer reproductive outcomes. Alterations in egg development and increased inflammation may contribute to infertility, the researchers suggest.
Research by UNSW reveals oestrogen reduces energy burning after eating, resulting in more stored fat around the body. Oestrogen's role in regulating body fat has implications for dietary advice and exercise regimes during pregnancy.
Research from the University of Illinois suggests that weight-loss campaigns promoting exercise may cause people to consume more food. Viewers exposed to messages urging physical activity ate significantly more than those who saw similar messages without a fitness focus.
A University of Illinois study has found that a hormone present in fat tissue plays a key role in regulating the immune system and aiding recovery from hypoxia. Leptin triggers an increase in anti-inflammatory molecules, leading to faster recovery times in obese mice.
A new study suggests that high levels of myostatin produced by muscle tissue in extremely obese individuals may contribute to the development of insulin resistance and Type 2 diabetes. Muscle loss is a key indicator of this transition, and understanding its role in metabolism is crucial for finding effective treatments.
A study funded by NIH found that overweight adults can achieve similar weight loss on different diets with varying proportions of fat, protein, and carbohydrates. Participants lost an average of 13 pounds at six months and maintained a 9-pound loss at two years.
A specific gene called protein kinase C beta (PKC beta) plays a crucial role in the weight-gain response to a high-fat diet. Mice genetically engineered to lack PKC beta showed minimal health effects and resisted fat-induced obesity, insulin resistance, and liver damage. The study suggests that blocking this gene could be a therapeutic...
Commercial weight-loss programs create unrealistic expectations and false beliefs, highlighting the need for regulation. Governments must require accreditation of providers and supply evidence-based information for claims.
Human ancestors' large brains required high-energy diets, while modern humans consume more calories and nutrients. The imbalance between energy intake and expenditure contributes to obesity worldwide.
A study of 22,211 people found that abdominal obesity increased the risk of migraine headaches in those aged 20-55, especially in women. Losing weight around the stomach area may be beneficial for reducing migraine risk in this age group.
Researchers discovered that omega-3 fatty acids protect against liver damage and insulin resistance caused by obesity. The study found that lipids called protectins and resolvins derived from omega-3 fatty acids reduced the incidence of liver complications in obese mice, leading to improved insulin tolerance.
Researchers found that knocking out the protein tyrosine phosphatase 1B (PTP1B) gene improves cardiovascular function in genetically fat mice with diabetes. The study suggests that PTP1B contributes to insulin resistance, which can lead to impaired nitric oxide dilation and vascular remodeling. By improving fine control of blood glucos...
A new classification system aims to provide a more accurate picture of a patient's health issues, complementing body measurements. The Edmonton Obesity Staging System has five stages, from stage 0 to stage 4, and offers specific treatment approaches for each stage.
A recent study found that individuals with new diagnoses are more likely to adopt healthier habits than those without recent new diagnoses. Smokers who received at least one diagnosis had 3.2 times the odds of quitting compared to those without a diagnosis.
A new study shows that losing weight is the most effective way to reduce obstructive sleep apnea (OSA) symptoms and associated disorders. The study found that weight loss of more than 20 pounds resulted in markedly lower OSA symptoms and improvements in co-morbidities such as hypertension, high cholesterol, and diabetes.
Researchers at UNC School of Medicine identified a gene that causes obesity when mutated, affecting metabolism without impacting appetite. The study's findings provide new insights into epigenetics and open possibilities for novel pharmacologic approaches to treating obesity.
The American Dietetic Association has released an updated position statement on weight management, emphasizing sustainable and enjoyable eating practices and daily physical activity. The new statement is based on the latest research and interventions, including weight-loss surgery and behavioral interventions.
Researchers at UT Southwestern Medical Center found that mice lacking collagen VI developed 'healthy' obesity when fed a high-fat diet, without inflammation or insulin resistance. The study highlights the role of collagen VI in modulating fat-cell physiology and its potential as a target for intervention.
The European Union's decision to allow orlistat to be sold OTC may not be beneficial for the public due to its limited effect on obesity management. The drug's high cost, approximately £1.47 per day in England, adds false credibility to quick fixes, highlighting the need for long-term lifestyle changes.
A study by researchers at UCSF found that behavioral weight-loss programs can significantly reduce urinary incontinence in overweight and obese women. Participants who lost an average of 17 pounds experienced a 47% reduction in incontinence episodes compared to those in the control group.
A six-month diet, exercise, and behavior modification program resulted in significant weight loss and reduced urinary incontinence episodes per week by nearly half. The study found that such programs can be an effective first-line treatment for overweight and obese women.
A study found that sleep apnea is strongly associated with decreased glucose metabolism and pancreatic function, independent of body fat. Another study linked chronic intermittent hypoxia from sleep apnea to liver disease progression in severely obese patients.
Researchers found significant differences in microbial composition among obese patients, gastric bypass surgery subjects, and normal-weight individuals. The study suggests that the gut microbiome plays a key role in energy harvesting, making people more susceptible to obesity.
A recent study published in the Journal of the American College of Surgeons found that morbidly obese patients are at higher risk for complications after colectomy. These complications include surgical site infections, wound openings, pulmonary embolisms and kidney failures.
A new study by UC Berkeley researchers reveals that disabling a key enzyme in fat cells allows mice to overeat without gaining weight. The enzyme, AdPLA, plays a crucial role in regulating fat metabolism and body weight, making it a promising target for obesity treatment.
The study identified six new genes associated with obesity, including TMEM18, KCTD15, and GNPDA2, which show a neural effect. These genes are active in brain cells and have been validated in multiple studies.
The UK government's three-year anti-obesity initiative has been criticized for allowing commercial sponsorships from companies like PepsiCo and Kelloggs, who contribute to the rising obesity problem. The Lancet Editorial argues that these partnerships are ill-judged and undermine the campaign's goal of behavior change.
A Dutch study published in BMC Public Health found that phone and internet counselling is effective for weight management in overweight workers. The study compared counselling via phone and e-mail with standard practice and found significant weight loss in all groups, with those in the phone group losing the most weight.
Researchers at Karolinska Institutet found that mice exposed to low temperatures develop more blood vessels in adipose tissue, leading to faster fat metabolism. This discovery offers new therapeutic avenues for obesity and metabolic diseases.
Children's researchers found that ER stress and unfolded-protein response block leptin action in the brain; chemical chaperones can re-sensitize the brain to leptin, leading to significant weight loss. Leptin-sensitizing agents may bring new hope for obesity treatment
Researchers at Baylor College of Medicine found that the COUP-TFII protein helps control fat cells and energy metabolism. Breeding mice with only one copy of the gene led to smaller fat cells and increased sensitivity to insulin, making it a potential target for diabetes treatment.
Researchers from Loyola University Health System found no significant difference between African American women in metropolitan Chicago and Nigerian women in terms of calories burned during physical activity. The study suggests that dietary intake may be more important than energy expenditure level in the rising rates of obesity.
A new study published by the American Cancer Society found that obesity may contribute to the development of ovarian cancer through a hormonal mechanism. Women who were obese had an almost 80% higher risk of ovarian cancer compared to those of normal weight, particularly in women who had never used menopausal hormone therapy.
Researchers found that obese and non-obese patients have the same overall survival rate for ovarian cancer if their chemotherapy doses are tailored to their individual body weight. The study, published in Gynecologic Oncology, challenges earlier research suggesting obesity reduces ovarian cancer survival rates.
A high-fat diet can affect circadian rhythms, leading to hormone imbalance, obesity, psychological disorders, and cancer. Fasting and a low-fat diet regulate adiponectin signaling pathways, while a high-fat diet disrupts these pathways, contributing to metabolic disorders.
A study published in Preventive Medicine found that rural Americans who regularly eat at buffets and engage in low physical activity are more likely to be obese. The research also highlights the importance of community-friendly transportation and access to healthy foods in reducing obesity rates.
A recent study by the University of Alberta found that individuals with sarcopenic obesity, a condition characterized by low lean muscle mass, had significantly reduced survival rates and poorer physical function compared to those with only obesity. This suggests that body composition may play a crucial role in cancer treatment outcomes.
The University of Illinois Chicago's ImpacTeen project will study policy and environmental factors influencing youth behaviors related to nutrition, physical activity, obesity, and tobacco use. Researchers will assess state policies, school wellness programs, and community environments to inform effective policy and decision-making.
A recent study published in the journal Risk Analysis found that eating one egg per day has a negligible impact on coronary heart disease (CHD) risk in healthy adults. The study suggests that lifestyle factors such as poor diet, smoking, and physical inactivity contribute significantly to CHD risk.
Researchers say that GPs could do more to help obese individuals avoid surgery by implementing early stage weight management programs and using anti-obesity drugs. Patients face a post-code lottery when seeking access to specialist care, highlighting the need for improved obesity management strategies.
Researchers discovered a significant association between psoriasis and high levels of leptin, an obesity-related hormone that contributes to metabolic abnormalities. The study also found that body weight loss can decrease leptin levels and improve insulin sensitivity, potentially reducing the risk of cardiovascular diseases.
A new study found six genes linked to body mass index and obesity, with five impacting brain function. The discovery sheds light on how some people may be genetically wired to overeat, challenging societal views of obesity as a moral failing.
A study found that sugar-sweetened beverage consumption among US adults increased by 46 kilocalories per day and rose to 20% of daily calorie intake. The highest consumption was among young adults, while the elderly consumed the least.
According to the study, one in three UK adults (32.1% of men, 33.1% of women) will be obese by 2012, with a significant increase in obesity prevalence among low-income groups. The findings also highlight the economic burden of obesity, with an estimated £7.4 billion annual cost to the English economy.
Researchers found that economic incentives, such as lottery-based groups and deposit contracts, were highly effective in inducing initial weight loss. The study's results showed a significant difference in weight loss between the incentive groups and the control group.
A twin study found that identical and fraternal female twins had distinct gut microbial communities, but shared a common core set of genes that performed key functions. Obese individuals had an increased representation of bacterial genes devoted to extracting calories from food.
A five-year study found that older adults with symptoms of depression are more likely to gain abdominal fat, but not overall fat. Depression is associated with an increase in visceral fat, which may contribute to the development of diabetes and cardiovascular disease.
A recent study found that bariatric surgery leads to improvement of histopathological features of nonalcoholic fatty liver disease (NAFLD) in most patients. The risk of progression of inflammatory changes and fibrosis is minimal, with complete resolution of NAFLD reported in a majority of patients.
Research suggests that tributyltin, a persistent pollutant, affects gene activity and promotes the growth of fat storage cells in animals, potentially contributing to the obesity epidemic. The chemical's impact on retinoid X receptors, which regulate metabolism, is a recent discovery.
Research found that workers with high levels of alanine aminotransferase (ALT) and central obesity had significantly higher self-reported fatigue after work. The study suggests that objective measures such as elevated ALT and increased waist circumference are associated with work-related fatigue in apparently healthy workers.
A Penn State study found that obese rats are less sensitive to sweet tastes and prefer sweeter foods due to a weakened response to weak concentrations, leading to a vicious circle of overeating and sugar cravings. The research suggests that the brain's reward center is affected by the increased consumption of sugary foods.
Researchers discovered a molecule called NAPE that signals the brain when the stomach is full, reducing hunger. In studies with mice and rats, NAPE treatment led to significant weight loss and reduced appetite, suggesting potential for new obesity treatments.
Researchers discovered adiponectin is a metabolic link between obesity and reduced bone mineral density. Adiponectin levels were lower in obese humans and mice compared to lean controls. Higher levels of adiponectin impede bone development, leading to weaker bones and increased risk of fractures.
Researchers analyzed data from 13 prospective studies involving over half a million participants and found no link between fat, protein, or meat intake and kidney cancer. The study's findings suggest that the cause of increasing kidney cancer incidence worldwide remains unclear.
A new study finds that regular aerobic exercise significantly reduces anger expression and aggressive behavior in overweight but otherwise healthy children. The 10-15 week afterschool exercise program improved the children's ability to control their anger and aggression, according to the Pediatric Anger Expression Scale.
A non-invasive device has been shown to treat obesity and resolve diabetes in an animal model by altering complex gastrointestinal signals. The procedure resulted in a significant reduction in food intake and weight loss, as well as restoration of normal glucose metabolism.
A randomized trial involving 234 obese women found that telephone counseling and face-to-face follow-up sessions were more effective than weight loss education alone in maintaining weight loss, especially in rural communities where healthcare barriers are significant. Telephone counseling was also found to be cost-efficient.
Researchers identify COPI complex as a regulator of lipid homeostasis, finding it reduces PAT protein expression at the lipid droplet surface. This study reveals COPI's role in energy storage and shedding, with implications for treating obesity and metabolic disorders.
A review of bariatric surgery among women of reproductive age suggests that rates of adverse outcomes for mothers and newborns are lower after the procedure. Lower maternal complication rates were found in women who underwent bariatric surgery compared to those who were obese, with reduced rates of gestational diabetes and preeclampsia.